INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2012
·
IF 2.237
Jianhua Guo,Renxiang Ruan,Ying Zhang
Phenolic compounds in bio-oil are not stable and difficult to be upgraded to ideal fuels. In this study, simulated bio-oil as well as phenolic compounds separated from bio-oil by glycerol-assisted distillation were hydrotreated by Ru/SBA-15 catalyst and completely converted into C3 to C10 alcohols at mild conditions, which could be a feasible way to transfer the phenolic compounds in bio-oil or other real systems from lignin decomposition into high heating-value liquid fuel or fuel additives. The stability of the Ru/SBA-15 catalyst was also investigated. It was found that Ru/SBA-15 was stable with phenolic compounds in the simulated bio-oil but not in a real one.
研究领域:
能源生物学
·
催化化学
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DOI
高影响因子
ENVIRONMENTAL TECHNOLOGY
·
2025
·
IF 2
Chunyun Gu,Jiayi An,Shuyu Liu,Feng Xiong,Wei Zhou,Liting Tian,Yuruo Wan,Qian Wu,Jie Ma
Oxidants used in the ISCO technology usually require activation by activators to degrade contaminants. However, this study investigated degradation of 15 typical halogenated hydrocarbons by five common ISCO oxidants (PS, PMS, H2O2, KMnO4, SPC) without activation in both pure water and real groundwater. Unactivated PS could degrade 14 halogenated hydrocarbons, excluding tetrachloromethane. Unactivated KMnO4 could degrade chlorinated alkenes. Unactivated SPC could degrade 1,1,2,2-tetrachloroethane by a base-promoted second-order elimination reaction. PMS, H2O2, and SPC could be activated by the natural matrix constituents in groundwater, enabling them to degrade some halogenated hydrocarbons. Among the 15 halogenated hydrocarbons studied, only tetrachloromethane cannot be degraded by any oxidant due to its carbon being in its highest oxidation state. The experimental data in the pure water indicate that the overall degradation rate of unactivated PS for chlorinated alkanes increased with increases in the number of chlorine substituents. The degradation rate of unactivated PS for halogenated hydrocarbons decreased with increases in the carbon chain length. Chlorinated alkenes are more easily degraded than chlorinated alkanes while chlorinated alkanes are more readily degraded than brominated alkanes. The degradation rate of unactivated KMnO4 for chlorinated alkenes decreased with increases in the number of chlorine substituents and decreased with increases in the carbon chain length. Overal, results of this study show that unactivated ISCO is a promising and environmentally friendly in-situ remediation technology that may be a good candidate for the remediation of contaminated sites by halogenated hydrocarbons.
研究领域:
环境科学
·
化学工程
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DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2026
·
IF 6.6
Le Yu,Hong Li,Zhaoyi Xu,Shourong Zheng,Tao Long,Wang Lei
Ultrafine Pd nanoparticles were stabilized on aminopropyl-functionalized SBA-15. • The catalyst enabled efficient FA decomposition and TCE hydrochlorination. • Successful TCE removal was achieved through FA-driven catalytic hydrogenation. Trichloroethylene (TCE), a persistent and highly toxic groundwater contaminant, demands efficient remediation strategies. Formic acid (FA, HCOOH)-assisted catalytic hydrodechlorination (HDC) is a promising approach for TCE removal, with Pd-based catalysts exhibiting excellent activity for both FA dehydrogenation and C-Cl bond hydrogenation. This study investigates an amino-functionalized SBA-15-supported Pd catalyst (Pd/SBA-15-NH 2 ) for TCE degradation in the FA-driven hydrogenation system. TEM and XPS characterization showed that the amino groups significantly enhance Pd dispersion and stabilize positively charged Pd δ+ species, furthermore in-situ DRIFTs tests conclusively confirmed that HCOO* species serve as the key intermediates in the FA dehydrogenation process, DFT study also showed Pd/SBA-15-NH 2 have lower free energy and thus improve the activity of FA dehydrogenation. Kinetic analysis confirmed a pseudo-first-order pathway with an TOF of 208.6 h −1 and apparent activation energy of 46.6 kJ/mol. Under optimized conditions (pH = 5.6, 25 °C), the catalyst achieved 100% TCE conversion in 120 min with a initial activity of 0.072 mM/(g min). Meanwhile, ethane (C 2 H 6 ) as the dominant reaction product, indicating that TCE degradation proceeds via a one-step rather than dechlorination mechanism. These findings provide valuable insights for catalytic dichlorination mechanism for chlorinated ethenes, while highlighting the theoretical foundation for the development of high-performance, noble metal-based catalysts in environmental applications. Download: Download high-res image (107KB) Download: Download full-size image
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DOI
高影响因子
Cell Reports Medicine
·
2025
·
IF 10.6
Huifang Wang,Liuhai Zheng,Chuanbin Yang,Lin Jia,Runhua Zhou,Hongda Liu,Yafang Dong,Xiaolong Xu,Guangwei Shi,Jialu Yang,Yang Li,Haitao Yuan,Jinpeng Cen,Guiming Zhang,Le Yu,Tianqi Guo,Haibo Jiang,Yawei Liu,Xijun Wang,Zhijie Li,Jigang Wang
T cell inadequacy or exhaustion often causes the failure of immune checkpoint blockade (ICB)-based immunotherapy. Interleukin-15 (IL-15) has been used to prime the tumor microenvironment (TME) to boost the efficiency of immunotherapy. However, its clinical application is hindered by systemic toxicity and low intratumoral concentrations. Here, we engineer the probiotic Escherichia coli Nissle 1917 to deliver IL-15 and croconium dye, enabling the TME-responsive release of IL-15 and amplifying the antitumor effect through photothermal therapy. This promotes the recruitment of antigen-presenting cells and T cells and the expansion of T/natural killer cells induced by IL-15. Consequently, it halts the tumor growth and induces systemic memory T cell production. This approach combined with ICBs generates prominent synergistic effects across various immune-hot and immune-cold tumors. This study provides a strategy for targeted delivery of cytokines, demonstrating its high potential for TME reprogramming when combined with immunogenic cell death inducers.
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DOI
PubMed
高影响因子
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2022
·Vol. 38
·期 6
·1504-1511
·
IF 2.726
He Kai,Liu Shijia,Zhao Guiyan,Qin Yucai,Bi Yanfeng,Song Lijuan
A series of Ni-W catalysts supported on mesoporous SBA-15 with different Ni:W ratios(Ni x W/SBA-15, Ni-5%, x =1, 10, 50) was prepared and fully characterized by powder X-ray diffraction(PXRD), Brunner-Emmet-Teller(BET), transmission electronic microscopy(TEM), H 2 -temperature programmed reduction(H 2 -TPR), and X-ray photoelectron spectroscopy(XPS). High-resolution TEM images, XPS measurements, H 2 -TPR experiments coupled with PXRD results determined the evolution of Ni and W species. It is found that a trace amount of W from H 2 WO 4 can significantly improve Ni dispersion on SBA-15 (Ni 50 W/SBA-15) with Ni 0 and non-stoichiometric WO x species as small as ca . 3.6 nm. The prepared Ni x W/SBA-15 was utilized for CO 2 hydrogenation, which showed that a higher W content restrained the CO 2 hydrogenation while a lower W ratio promoted both conversion rate and selectivity for methane compared with Ni/SBA-15. The Ni 50 W/SBA-15 catalyst showed the best performance with a 93.3% CO 2 conversion rate and 99.7% selectivity for methane at 400 o C under 0.1 MPa and maintained ca . 97% initial performance for 24 h. Tracking product evolution experiments by in-situ Fourier transform infrared spectrascopy(FTIR) indicated that a small amount of W can modify the surface of Ni particles by geometric coverage and electronic modification, which facilitates the adsorption of the CO intermedia and results in the formation of CH 4 . This work provides a new clue to fabricating efficient CO 2 conversion bimetallic materials.
研究领域:
催化化学
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环境化学
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材料科学
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能量转换
·
二氧化碳利用
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DOI
高影响因子
Journal of Materials Chemistry A
·
2013
·Vol. 1
·期 9
·3171-3176
·
IF 0
Jian Zhi,Sheng Deng,Yuxuan Zhang,Youfu Wang,Aiguo Hu
A three dimensional porous carbon nanomembrane (CNM), silica-supported CNM (SS-CNM), is developed by formation of a self-assembled monolayer of an enediyne compound on the surface of mesoporous silica (SBA-15) followed by Bergman cyclization and carbonization. The SS-CNM is applied as a conductive support for the electroactive material Co3O4 to fabricate advanced supercapacitors. A large fraction of Co3O4 clusters (66% of total weight) are impregnated in the SS-CNM host to form regularly packed nanorods with diameters of 7 nm. The specific capacitance of the supercapacitor electrode material reaches 1086 F g−1 (1645 F g−1 based on Co3O4) with aqueous electrolyte. This extraordinary high performance of the electrode material is attributed to the unique pore structure of the SS-CNM support that enhances the use of active material and shortens the transport path of ions and electrons.
研究领域:
材料科学
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储能
·
纳米技术
·
电化学
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DOI
Royal Society Open Science
·
2022
·Vol. 9
·期 9
·
IF 3.653
Haijun Cheng,Chang Yu,Hongyun Wang,Xiongmin Liu,Li Ma,Fang Lai
It has been a challenge to synthesize macrolide musk in excellent yields with high purity. KF-La/γ-Al2O3 catalyst was prepared from a highly basic mesoporous framework using a mild method. The prepared KF-La/γ-Al2O3 catalyst was employed for the synthesis of cyclopentadecanolide from methyl 15-hydroxypentadecanoate. The morphology and structure of prepared catalysts were characterized using XRD, TG-DTG, SEM, EDX, TEM, BET and CO2-TPD. The results revealed that the K3AlF6 and LaOF are produced on the surface of KF-La/γ-Al2O3, and LaO can promote the dispersion of KF on the surface of Al2O3. Catalysts pore size main distribution ranges between 10 and 30 nm, the maximum CO2 desorption temperature is 715°C when the La loading is 25%. Because F− ion has a higher electronegativity than O2− ion, the KF-promoted metal oxide (Al2O3 or/and La2O3) contained more strong basic sites, compared with that of the corresponding metal oxide. The yield of cyclopentadecanolide obtained at 0.5 g KF-25La/γ-Al2O3 catalyst and a reaction temperature of 190°C for 7 h were 58.50%, and the content after reactive distillation is 98.8%. The KF-La/γ-Al2O3 catalyst has a larger pore size and basic strength, which is more conducive to the macrolactonization of long-chain hydroxy ester.
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PubMed
高影响因子
EUROPEAN JOURNAL OF PHARMACOLOGY
·
2022
·
IF 5.195
Yi-sheng Zeng,Jian Peng,Xiao-fang Gao,Dong Tian,Wei Zhan,Jin Liu,Xiao-jun Hu,Sheng Huang,Shu-ting Tian,Lan Qiu,Ai-ling Liang,Fu-yu Wang,Ren-han Dong,Bing Guang,Tai Yang
As a key mediator of cell death and inflammation, receptor-interacting protein kinase 1 (RIPK1) responds to a broad set of inflammatory and pro-death stimuli in human diseases. Inhibitors targeting RIPK1 are being investigated for the treatment of a wide range of human diseases, including ulcerative colitis . In the present study, we designed, synthesized, and investigated the anti-necroptosis and RIPK1-inhibition effects of SZ-15—a symmetrical high-molecular-weight (>500 Da) compound. SZ-15 effectively inhibited necroptosis in U937 and HT-29 cells at concentrations of 1 nM and 10 nM, respectively, and SZ-15 at a concentration of 10 nM almost completely blocked RIPK1, RIPK3, and mixed-lineage kinase domain-like (MLKL) protein phosphorylation induced by necrosis inducers. SZ-15 suppressed the pro-necroptosis function of RIPK1 by downregulating the mRNA expression of pro-inflammatory cytokines, including tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6. The activities of SZ-15 were effectively restricted to the gut: The percent recovery of the parent form of SZ-15 in mouse feces was 85.75%. Nevertheless, SZ-15 was effectively absorbed and detected in colon tissues after 1 h at a concentration of 3335 ± 868 ng/g, indicating that membrane permeability was maintained. SZ-15 alleviated dextran sulfate sodium (DSS)-induced ulcerative colitis in vivo by decreasing TNF-α, IL-1β, IL-22, and IL-6 mRNA expression in colonic tissues. Our preclinical study describes a novel gut-restricted RIPK1 inhibitor that shows great potential for use in the clinical treatment of ulcerative colitis.
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PubMed
高影响因子
CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2017
·
IF 1.174
Tianhan Zhu,Hua Song,Xueya Dai,Hualin Song
The Al-doped Ni 2 P/Al-SBA-15 catalyst with high hydrodeoxygenation (HDO) activity was synthesized by temperature programmed reduction at a relatively low reduction temperature of 400 °C. The as-prepared catalyst was characterized by X-ray diffraction (XRD), H 2 temperature-programmed reduction (H 2 -TPR), X-ray photoelectron spectroscopy (XPS), transmission electron microscope (TEM), NH 3 temperature programmed desorption (NH 3 -TPD), N 2 adsorption–desorption and CO uptake. The effect of Al on benzofuran (BF) HDO performance was investigated. The result indicates that the incorporation of Al into the SBA-15 support can promote the formation of much uniform, smaller, highly dispersed Ni 2 P particles on the catalyst. The Al also contributes to suppress the enrichment of P and promote more exposed Ni sites on the surface. In addition, the incorporation of Al can enhance the acid strength. The total deoxygenated product yield over Ni 2 P/Al-SBA-15 reached 90.3%, which is an increase of 19.4%, when compared with that found for Ni 2 P/SBA-15 (70.9%).
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高影响因子
Reaction Chemistry & Engineering
·
2020
·Vol. 5
·期 9
·1833-1844
·
IF 3.441
Guochao Yang,Lingtao Wang,Haoxi Jiang
Upgrading bio-ethanol into high value chemicals is an important issue in biomass conversion, and conversion of ethanol into butadiene is one of the most feasible methods. Here Zr-incorporating mesoporous SBA-15 (Zr–SBA-15) materials with different Si/Zr ratios were successfully synthesized by a one-pot method and were employed as catalysts for the conversion of the ethanol (EtOH)–acetaldehyde (AcH) mixture to butadiene. The textural structure and acidity of Zr–SBA-15 were investigated by using XRD, N2 adsorption, TEM, FT-IR, UV-vis, XPS, NH3-TPD and Py-IR, and the results of these characterizations indicated the mesoporosity of Zr–SBA-15 and confirmed the incorporation of Zr into the framework. Zr–O–Si bonds were formed by the incorporation and exhibited Lewis acidity predominantly. The influence of the Si/Zr ratio and reaction conditions (temperature, EtOH/AcH ratio and WHSV) showed that a suitable Si/Zr ratio was needed to balance the butadiene selectivity, by-product selectivity and total conversion. Amongst the prepared catalysts, Zr–SBA-15-20 achieved the best butadiene selectivity of 74.0% at a relatively low temperature (275 °C). The good catalytic performance could be attributed to the homogeneous dispersion of Zr species and Zr–O–Si bond generated by Zr incorporation. Furthermore, EtOH-TPD and AcH-TPD experiments proved the essential role of acetaldehyde addition and the well-accepted reaction pathway.
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高影响因子
MICROPOROUS AND MESOPOROUS MATERIALS
·
2020
·
IF 4.551
Yue Zhang,Li Wang,Nan Wang,Guohua Gao,Zhiyong Pan,Baoning Zong
Monodispersed mesoporous SBA-15 silica was synthesized by adding n -decane to conventional synthesis recipe. Pd catalysts for 2-alkyl-anthraquinone hydrogenation were then prepared on the as-synthesized SBA-15 and characterized by scanning and transmission electron micrographs, X-ray diffraction, XPS spectroscopy and N 2 adsorption-desorption. At the molar ratio of n -decane to P123 (C10/P123) ranging between 120 and 240, monodispersed SBA-15, together with the shortened length of pore channels, expanded size of mesopores and decreased proportion of micropores could be obtained. The Pd catalyst on SBA-15 synthesized with 240 in C10/P123 exhibited the superior catalytic performance. The initial hydrogenation rate of 2-ethyl-, tert-butyl- and amyl-anthraquinone increases by approximately 300%, 183% and 150% compared with that on SBA-15 synthesized using a recipe without n -decane, with the selectivity to active anthraquinone of >99%.
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高影响因子
POLYMER BULLETIN
·
2020
·Vol. 78
·期 10
·5741-5753
·
IF 2.014
Yue Longlong,Xie Qian,Yang Yifeng,Li Jing,Li Xiancai
The preparation of a lanthanum ion-imprinted polymer is described via surface ion imprinting, with polyethyleneimine as the functional monomer and SBA-15 as the matrix material. Its structure was characterized and analyzed, and static adsorption experiments were carried out to determine the best experimental conditions for the adsorption of lanthanum ions. The effects of initial concentration, temperature, adsorption time and pH on the adsorption of lanthanum ion surface-imprinted polymer were investigated. In addition, the regeneration performance of La(III)-IIP-PEI/SBA-15 on lanthanum ion was studied and showed that La(III)-IIP-PEI/SBA-15 has strong specific recognition ability and high reuse performance.
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高影响因子
危险品化学品经营许可证（带存储）