Advances in Materials Science and Engineering
·
2022
·Vol. 2022
·期 1
·7408284
·
IF 2.098
Zhenhao Wei,Yufan Ji,Yiping Huang,Jingjing Huang,Yunguo Huang,Changhai Yue,Junzhou Li,Mingwei Tang,Yunfang Liu,Hanfei Liu,Hao Zhu,Kai Zhu,Fan Yang,Xuedong Zhu
Zinc (Zn) and cerium (Ce) modified hierarchical ZSM-5 (HZ) catalysts were prepared by incipient wetness impregnation, and their catalytic performances in methanol to aromatics reaction were evaluated in a fixed-bed reactor operating at 400°C under 0.1 MPa and WHSV of 1.0 h −1 . The structure, acidity, and state of Zn species of the Zn/Ce modified HZ catalysts were investigated via several characterization techniques, including XRD, NH 3 -TPD, H 2 -TPR, nitrogen adsorption, and XPS. The results showed that the aromatization activity of 2 wt% Zn-modified HZ (2% Zn/HZ) could be significantly enhanced by loading 0.6 wt% Ce, which was mainly attributed to the increase in surface ZnOH + species. Moreover, it was found that Ce inhibited pore blockage caused by Zn. Consequently, compared to 2% Zn/HZ, 2% Zn-0.6% Ce/HZ exhibited higher aromatic selectivity and longer catalyst lifetime.
研究领域:
催化化学
·
材料科学
✓ 已验证
DOI
高影响因子
Reaction Chemistry & Engineering
·
2025
·
IF 3.1
Wei Qi,Yuqi Chen,Liangzhi Li,Xin Ju,Hongwei Chen,Lishi Yan
The catalytic conversion of fructose to 5-hydroxymethylfurfural (5-HMF) in ternary deep eutectic solvent (DES)/methyl isobutyl ketone (MIBK) biphasic system at mild temperatures (50~70 ℃) was investigated in this work. The ternary DES consists of choline chloride (ChCl), benzene sulfonic acid (BSA) and ethylene glycol (EG) were physiochemical characterized by FT-IR and 1H NMR. The ternary DES(ChCl-BSA-EG)/MIBK biphasic system (ChCl/BSA/EG=2:1:1) resulted in 82.0% 5-HMF yield and 96.2% corresponding selectivity at 60 °C for 2 h. The kinetic analysis further revealed that the rate constant of fructose dehydration (k1) was much higher than the rate constant of 5-HMF conversion (k2). The calculated ratio of k1/k2 was 16.1. The proposed reaction mechanism suggested that the synergetic effect of the three components of ternary DES facilitates the elimination of water molecules from fructose and the formation of 5-HMF, while the MIBK extraction phase suppress the byproducts of 5-HMF as well. The present work provides a green and sustainable pathway for 5-HMF production with high yield and high selectivity at mild temperatures.
研究领域:
化学工程
·
绿色化学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2015
·
IF 3.391
Zhenhua Zhang,Yueyu Zou,Taigang Wu,Caihuan Huang,Kehan Pei,Guangwen Zhang,Xiaohua Lin,Weibin Bai,Shiyi Ou
Chlorogenic acid (CGA) is a phenolic acid that ubiquitously exists in fruits. This work aims to investigate whether and how CGA influences HMF formation during heating fructose alone, or with an amino acid. The results showed that that CGA increased 5-hydroxymethylfurfural (HMF) formation. At pH 5.5 and 7.0, the addition of 5.0 μmol/ml CGA increased HMF formation by 49.4% and 25.2%, respectively when heating fructose alone, and by 9.0% and 16.7%, respectively when heating fructose with aspartic acid. CGA significantly increased HMF formation by promoting 3-deoxosone formation, and its conversion to HMF by inhibiting HMF elimination, especially in the Maillard reaction system. A comparison of the catalytic capacity of CGA with its six analogous compounds showed that both its di-hydroxyphenyl and carboxyl groups function in increasing HMF formation.
研究领域:
食品科学
·
化学
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Jinghua Wang,Hongyou Cui,Jiangang Wang,Zhihe Li,Ming Wang,Weiming Yi
Conversion of glucose to 5-hydromethyl furfural (HMF) and levulinic acid (LA) was systematically investigated in LiCl·3H 2 O without additional catalyst. Based on the experimental investigations by using glucose, fructose and HMF as the reaction substrate separately, corresponding reaction kinetics in LiCl·3H 2 O were modelled by first-order assumption. Kinetic analysis demonstrates that high temperature favors the formation of LA, while low temperature facilitates to selectively form humins. To achieve high LA yield, at least a temperature of 140 °C is required. Without additional catalyst converting glucose to LA in LiCl·3H 2 O, humins was predominantly derived from glucose and HMF, and glucose isomerization is the reaction rate-determining step. The activation energies of the main reactions are 160.96 kJ/mol (glucose to HMF), 139.20 kJ/mol (fructose to HMF), and 71.81–76.48 kJ/mol (HMF to LA) respectively. The activation energies for humins formation were 23.45 kJ/mol from glucose, 49.54 kJ/mol from fructose, and 42.15–65.85 kJ/mol from HMF, respectively. It is verified that LiCl·3H 2 O, as compared to aqueous medium, is an excellent reaction medium for converting glucose to LA as it can provide the active centers for fructose to HMF reaction and HMF to LA reaction, but lack of highly efficient Lewis acid for glucose isomerization. With the addition of Lewis acid (such as AlCl 3 and FeCl 3 ), as high as 83.4% of LA yield can be obtained respectively when directly converting glucose, with the total selectivities of LA and HMF of 95%.
研究领域:
生物化学
·
催化化学
✓ 已验证
DOI
高影响因子
JOURNAL OF CHEMICAL RESEARCH
·
2017
·
IF 0.646
Da-Hua Shi,Hui-Long Zhu,Yu-Wei Liu,Zong-Ming Tang,Chen Lu,Xiao-Dong Ma,Xiao-Kai Song,Wei-Wei Liu,Tong Dong,Meng-Qiu Song
Three novel 5-benzyl-1,3,4-thiadiazole derivatives were synthesised starting from phenylacetic acid derivatives. These compounds were characterised by NMR, HRMS and single-crystal X-ray diffraction analysis. 2-Pyrrolidyl-5-[2-(4-bromophenyl)methyl]-1,3,4-thiadiazole showed moderate acetylcholinesterase-inhibition activity with a 50% inhibitory concentration value of 33.16 μM. 2-Pyrrolidyl-5-[2-(4-bromophenyl)methyl]-1,3,4-thiadiazole and acetylcholinesterase docking was demonstrated using the Molecular Operating Environment program.
研究领域:
药物化学
·
神经生物学
·
有机化学
✓ 已验证
DOI
高影响因子
ACS Applied Bio Materials
·
2022
·
IF 0
Chun-Xia Zhang,Hong-Wei Li,Renwen Zhang,Zhongyuan Ren,Yuqing Wu
In the present work, cytidine 5′-monophosphate capped gold nanoclusters (AuNCs@CMP) are reported as a catalyst for redox reactions, which show both oxidase- and excellent peroxidase-like activity. When employing 3,3′,5,5′-tetramethylbenzidine (TMB) as a substrate in the presence of hydrogen peroxide (H2O2), the maximum velocity (Vmax) was 175 × 10–8 M s–1in vitro. Besides, the AuNCs@CMP exhibited high catalytic activity for reactive oxygen species (ROS) generation with H2O2. Particularly, they also displayed excellent catalytic activity for ROS generation in tumor cells, being activated and promoted by the tumor microenvironment (TME). Consequently, the AuNCs@CMP show an excellent antitumor effect on HeLa and SW480 cells as assayed by flow cytometry. The antitumor mechanism of AuNCs@CMP was attributed to the high ROS generation based on the specific environments of the TME. Therefore, the present study provides TME-adaptive AuNCs@CMP with excellent mimetic peroxidase activity, producing significant ROS to kill the tumor cells in TME.
研究领域:
纳米医学
·
肿瘤学
·
催化
·
生物化学
✓ 已验证
DOI
PubMed
JOURNAL OF HAZARDOUS MATERIALS
·
2024
·
IF 12.2
Zuhao Chen,Yongyou Hu,Guanglei Qiu,Donghui Liang,Jianhua Cheng,Yuancai Chen,Xiaoqiang Zhu,Guobin Wang,Jieyun Xie
The effects of antibiotics, such as tetracycline, sulfamethoxazole, and ciprofloxacin, on functional microorganisms are of significant concern in wastewater treatment. This study observed that Acinetobacter indicus CZH-5 has a limited capacity to remove nitrogen and phosphorus using antibiotics (5 mg/L) as the sole carbon source. When sodium acetate was supplied (carbon/nitrogen ratio = 7), the average removal efficiencies of ammonia-N, total nitrogen, and orthophosphate-P increased to 52.46 %, 51.95 %, and 92.43 %, respectively. The average removal efficiencies of antibiotics were 84.85 % for tetracycline, 39.32 % for sulfamethoxazole, 18.85 % for ciprofloxacin, and 23.24 % for their mixtures. Increasing the carbon/nitrogen ratio to 20 further improved the average removal efficiencies to 72.61 % for total nitrogen and 97.62 % for orthophosphate-P (5 mg/L antibiotics). Additionally, the growth rate and pollutant removal by CZH-5 were unaffected by the presence of 0.1–1 mg/L antibiotics. Transcriptomic analysis revealed that the promoted translation of aceE , aarA , and gltA genes provided ATP and proton -motive forces. The nitrogen metabolism and polyphosphate genes were also affected. The expression of acetate kinase, dehydrogenase, flavin mononucleotide enzymes, and cytochrome P450 contributed to antibiotic degradation. Intermediate metabolites were investigated to determine the reaction pathways.
研究领域:
环境微生物学
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废水处理工程
·
分子生物学
✓ 已验证
DOI
高影响因子
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
·
2017
·
IF 3.471
Yunwu Zheng,Fei Wang,Xiaoqin Yang,Yuanbo Huang,Can Liu,Zhifeng Zheng,Jiyou Gu
The main objective of this work was to study aromatics production via the catalytic pyrolysis upgrading of biomass using metal-loaded modified H-ZSM-5. M-ZSM-5 catalysts were prepared through the impregnation method with Zn, Ga, Ni, Co, Mg and Cu. The prepared M-ZSM-5 catalysts were evaluated by x-ray diffraction, thermal desorption spectroscopy and scanning electron microscopy. The properties, composition and product distribution of bio-oil were also analysed. Results showed that the M-ZSM-5 catalysts yielded a higher amount of non-condensable gas at the expense of the liquid yields. The Ga-ZSM-5 catalysts produced the highest yields of bio-oil (25.76 wt%), but the lowest amount of coke (22.08 wt%) compared with the unmodified ZSM-5 catalyst (33.38 wt%). The content of the single-ring aromatics prepared by using the Zn-ZSM-5 catalysts was the highest at 90.28 wt%, whereas that of the polycyclic aromatic hydrocarbon prepared by the Ni-ZSM-5 catalysts was the highest at 31.36 wt%. Moreover, the selectivity of the single-ring aromatic hydrocarbons, such as C7 and C8, were significantly affected by the use of the M-ZSM-5 catalysts. The Zn-ZSM-5 catalysts were the most selective for toluene and xylenes with contents of 36.52 wt% and 35.32 wt%, respectively, whereas the Co-based catalysts were the most selective for indene. The Ni-based catalysts can obviously improve the selectivities of benzene production and C10+ polycyclic aromatic hydrocarbons. Zn-ZSM-5 was the most effective catalyst that can be used in the production of aromatic hydrocarbons.
研究领域:
能源化学
·
催化材料科学
✓ 已验证
DOI
高影响因子
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
·
2025
·
IF 3.3
Ma Shutian,Shi Zhuang,Yang Yi,Zhang Jinglin,Zou Hongyu,Diao Enjie,Zhang Liming
Solo-bulb black garlics (SBBG) are novel foods rich in nutritional and functional ingredients. However, certain process contaminants formed during thermal processing of SBBG raise safety concerns. This study investigated the formations of 5-hydroxymethyl-2-furfural (5-HMF) and acrylamide, as well as the browning degree of SBBG during a 12-day aging period. Both 5-HMF and acrylamide contents exhibited exponential increases, with their formations well simulated by pseudo-first-order kinetic models. 5-HMF formation showed a significant positive correlation with fructose content ( p < 0.05), while acrylamide formation was strongly associated with asparagine content ( p < 0.01). Browning degree correlated significantly with acrylamide accumulation and asparagine content ( p < 0.01), but not with 5-HMF ( p > 0.05). These results indicate that fructose and asparagine accumulations play critical roles on 5-HMF and acrylamide formations in SBBG, respectively, and acrylamide accumulation promotes SBBG browning. Notably, acrylamide level in SBBG exceeded those reported in some commonly consumed foods, which is a concern considering the daily consumption of this food.
研究领域:
食品科学
·
营养学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIORESOURCE TECHNOLOGY
·
2019
·
IF 6.669
Caidi Jin,Ming Yang,Shuang E,Jianglong Liu,Shen Zhang,Xiaoliang Zhang,Kuichuan Sheng,Ximing Zhang
One-step fractionation with concentrated formic acid at elevated temperatures with short retention time was investigated for corn stover valorization. Crude pulp (CP) with high purity of cellulose and FA-lignin (FAL) with high guaiacyl content were fractionated through one-step mild pretreatment. Formylation reaction on both CP and FAL fractions occurred during the pretreatment and improved the hydrophobicity and thermal stability of CPs and FALs. The presence of formyl group on CPs significantly inhibited the enzymatic hydrolysis efficiency for sugar production, however, the formylated cellulose showed super high reactivity and selectivity for HMF production through catalysis by maleic acid and aluminum chloride in acetonitrile-water co-solvent system. In addition, the fractionated FAL fraction exhibited a loose structure which is prominent for its further catalytic conversion into chemicals and energy.
研究领域:
生物化学
·
可再生资源工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED CATALYSIS A-GENERAL
·
2018
·
IF 4.521
Jingjie Cao,Mingwei Ma,Jinchan Liu,Yongquan Yang,Hui Liu,Xingliang Xu,Jiahui Huang,Huijuan Yue,Ge Tian,Shouhua Feng
Aluminum ion-exchanged Ca-montmorillonite with different concentrations of aluminum ion were prepared and applied in the conversion of carbohydrates to 5-hydroxymethylfurfural (HMF). It was found that two types of acid sites were present in the catalyst, Lewis acid sites for isomerization of glucose and Brønsted acid sites for dehydration of fructose. With Al-mont-10 as catalyst, the yield of HMF converted from glucose was 80.4% in a biphase system (THF: NaCl solution) at 180 °C for 2.5 h. Further, the catalyst also shows excellent catalytic performance in the conversion of starch and inulin, and the yield of HMF reached 60.1% and 81.6% under identical conditions, respectively.
研究领域:
化学工程
·
催化科学
✓ 已验证
DOI
高影响因子
BIOORGANIC CHEMISTRY
·
2021
·
IF 5.275
Fang Guo,Tao Xia,Ping Xiao,Qingyue Wang,Zhitong Deng,Wang Zhang,Guowang Diao
Pillar[5]arene complexes of the naturally occurring compound bisdemethoxycurcumin (BDMC) were acquired for improving the water solubility and stability of BDMC. As a family member of curcuminoid compounds, BDMC has many interesting therapeutic properties. However, its low aqueous solubility and stability resulted in poor availability and restricted the clinical efficacy. Pillar[5]arenes with hydrophilic ends and a hydrophobic cavity could include with BDMC based on size matching. The synthesized hydrazide-pillar[5]arene (HP5A) and BDMC had a strong host–guest interaction with a 1:1 binding stoichiometry. Furthermore, the HP5A ⊃ BDMC complex could self-assemble into well-defined fibers in water/ethanol solution. This supramolecular complex worked well in vitro for inhibiting the proliferation of hepatoma carcinoma cells HepG2. Remarkably, this method of complexation with pillar[5]arenes visibly reduced the undesirable side effects on normal cells without weakening the anti-cancer activity of the drugs. We expected that the obtained host–guest complex and fibrous assembly would provide a promising platform for delivering drugs with low water solubility.
研究领域:
药物化学
·
肿瘤学
·
超分子化学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）