BIOMEDICINE & PHARMACOTHERAPY
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2021
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IF 6.53
Yi-yu Liang,Kun-wei Li,Feng-jv Niu,Ying Li,Hao-cheng Wei,Yun-lei Dai,Yun-yu Wang,Chang-zheng Zhou,Xin-huan Wan
Objective To investigate the antiviral effect of Salvia plebeia R. Br. polysaccharides (SPP) against RSV and underlying mechanisms. Methods SPP was extracted via alcohol-precipitation method and extract was separated into various fractions using ultrafiltration method. The polysaccharide content was determined using UV-Vis. Antiviral effect of SPP and fractions was measured using MTT method and Reed-Muench method. Sixty Balb/c mice were randomly divided into 6 groups, and received either Ribavirin or SPP. Their body weight and food intake were recorded every day throughout the experiment period. The lung index inhibition ratio and pulmonary virus titer were determined followed by the histological analysis of lungs. Furthermore, time-of-addition and effective stage analysis were carried out to determine the mechanism of action. The TLR-3 and TLR-4 levels in the lungs were determined using qRT-PCR. The levels of IFN-γ, IL-2 and TNF-α in serum were determined using ELISA. Results The SPP content is 4.396%. SPP has shown a good anti-RSV effect both in vitro (TI = 123.041) and in vivo models. The antiviral activity of fractions with molecular weight ≥ 10,000 is found to possess more potent antiviral activity than other fractions. SPP inhibits the RSV proliferation and reduces the lung lesions induced by RSV. The mechanism of action involves the inhibition of TLR-3 and TLR-4 in lungs, up-regulation of IFN-γ and IL-2, and down-regulation of TNF-α in serum. It is also shown to improve the body’s immune function. Conclusion SPP has a potential to treat diseases caused by RSV.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
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2019
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IF 8.355
Xinfeng Chen,Congming Sun,Yang Liu,Long Yu,Kui Zhang,Abdullah M. Asiri,Hadi M. Marwani,Hua Tan,Yuejie Ai,Xiangke Wang,Suhua Wang
As a new family of fluorescent materials, all inorganic perovskite quantum dots (PQDs) CsPbX 3 (Cl, Br, I) have attracted rising attention due to their intrinsic optical superiorities and potential applications in various fields. This work takes advantage of the bright fluorescence of PQDs and the strong electrophilic properties of picric acid (PA) to construct an analytical method for sensitive and selective discrimination of PA against other nitroaromatic explosives, and the limit of detection is as low as 0.8 nM. The quenching mechanism was elucidated as the formation of electrostatic complex and the electron transfer between PA and PQDs. To facilitate visual and on-site detection, the CsPbBr 3 PQDs were printed onto microfiltration membrane by inkjet printing to fabricate test papers for rapid and on-site detections of explosive and pollutant PA, showing a great research prospect in the detection of ultratrace PA at different sites.
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JOURNAL OF CATALYSIS
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2016
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IF 7.354
Haoran Yuan,Xiang Fang,Qiyi Ma,Jianyong Mao,Kexian Chen,Zhirong Chen,Haoran Li
The mechanism for aerobic oxidation of methylaromatic compounds using Co(CH 3 COO) 2 –Mn(CH 3 COO) 2 –KBr was further studied. The experimental results suggested that the intermediates (aromatic alcohols) are unexpectedly inert to direct oxidation via Co–Mn–Br catalysts under moderate conditions. In addition, it is found that both aromatic and aliphatic alcohols can inhibit the oxidation of the substrates and other intermediates (aromatic esters, aromatic aldehydes). UV–vis spectra indicated that oxidation from Co(II) to Co(III) would be interrupted in the presence of a given amount of alcohol. A plausible mechanism was also proposed. The intermediates analyzed by LC–MS and control experiments showed that aromatic alcohols prefer to undergo esterification rather than being directly oxidized as described in previous studies, and aromatic acetates are subsequently oxidized to corresponding aldehydes. According to the new mechanism, a strategy of highly selectively synthesizing aromatic alcohols and aldehydes from corresponding methylaromatic compounds was designed. The selectivities of aromatic alcohols and aldehydes could also be tuned by the added amount of CH 3 COOK.
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JOURNAL OF POWER SOURCES
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2024
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IF 8.1
Jiangxin Wang,Xiutao Liu,Chunkun Lin,Kaixin Zhang,Kuanhong Mei,Youhao Yang,Huibin Shi,Zizhu Wang,Yu Zhang,Shuo Li
The integrated design of solar energy conversion and storage systems has attracted increasing attention, and non-spontaneous redox reactions driven by dual photoelectrodes provide a potential solution to this issue. This study presents a solar rechargeable flow battery (SRFB) that combines dual photoelectrodes (BiVO 4 or Mo–BiVO 4 as photoanode, polyterthiophene (pTTh) as photocathode) with cost-effective redox pairs (Fe 3+ /Fe 2+ and Br 3 − /Br − ). The system charges under simulated solar illumination (100 mW∙cm −2 , AM 1.5G) and releases stored energy controllably as electrical energy. Research indicates the Mo–BiVO 4 photoanode and pTTh photocathode achieve an open-circuit voltage of 0.34 V and a short-circuit current density of 0.38 mA cm −2 . Using a specially designed Fe 3+ /Fe 2+ -Br 3 − /Br − (Fe–Br) SRFB device made via 3D printing, a charging photocurrent of approximately 1.9 mA cm −2 is attained. In constant current discharge tests, an initial discharge voltage of 0.23 V is observed at 0.1 mA∙cm −2 within the 10 discharge cycles, demonstrating system stability and offering a viable solution for low-cost, large-scale solar energy storage and conversion.
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ACS Applied Materials & Interfaces
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2017
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IF 7.504
Huiwen Liu,Zhennan Wu,Hang Gao,Jieren Shao,Haoyang Zou,Dong Yao,Yi Liu,Hao Zhang,Bai Yang
CsPbX3 (X = Cl, Br, I) nanocrystals (NCs) are competitive emitting materials for illumination and display because of their outstanding photophysical properties. However, the conventional synthetic approaches suffer from low yields, complex procedures, and toxic chemicals. In this work, we demonstrate a one-step microwave-assisted approach to prepare CsPbX3 NCs. The homogeneous heating and rapid temperature increment of microwave preparation facilitate the growth of CsPbX3 NCs, producing the NCs with high photoluminescence quantum yields up to 90%, narrow emission full-width at half-maximum, and emission color tunable from blue to red. By optimizing the preparation conditions of the microwave-assisted approach, CsPbX3 NCs with cation- and halide anion-controlled emission properties, tunable reaction rate, and enhanced stability are prepared. Light-emitting diode (LED) prototypes are further fabricated by employing the as-prepared CsPbX3 NCs as the color conversion materials on commercially available 365 nm GaN LED chips.
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Molecular Catalysis
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2024
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IF 3.9
Na Wei,Lin Liu,Jia-Qi Chu,Ting Fang,Zheng-Bo Han,Zhen Zhao
Metal-organic frameworks (MOFs) are widely studied for cycloaddition of CO 2 as a heterogeneous catalyst, because of their potential Lewis acidic sites and adjustable porous structure. However, most of them exhibit good catalytic performance need the assistance of nucleophilic co-catalysts. Herein, a novel MOFs and porous organic polymers (POPs) hybrid catalyst, core-shell ZIF-67@PDB-Br, is constructed by a convenient synthetic strategy, which possesses abundant Lewis acidic sites, imidazole cations and nucleophilic centers and shows robust chemical and thermal stability. This material demonstrates high-efficient catalytic activities and recyclability in the cycloaddition of CO 2 and propylene oxide without co-catalysts, the conversion and selectivity can reach 94.1 % and 99.0 %, respectively (100 °C, 1.0 MPa CO 2 pressure). Furthermore, the effects of the temperature, pressure, amount of catalyst and thickness of POPs shell on the catalytic activity were investigated. This study provides a viable direction for the development of synergistic heterogeneous catalysts for fixation of CO 2 without co-catalysts.
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Nano Energy
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2025
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IF 17.1
Jiangxin Wang,Yuancheng Zhong,Xu Zhang,Xianfeng Xu,Minmin Liu,Kuanhong Mei,Kaixin Zhang,Weiguo Xu,Shuo Li
The efficient integration of photovoltaic conversion and energy storage technologies is critical to overcoming constraints in solar energy utilization. Solar rechargeable flow batteries (SRFBs) integrate solar energy conversion and storage via photoelectrode-driven redox processes, enabling economically viable pathways for sustainable solar energy storage. However, SRFB development faces limitations of thermodynamic voltage ceilings imposed by photoelectrode/redox couple energy level mismatches and the long-term durability of photoelectrodes. In this study, a PANI/BiVO 4 (PBVO) photoelectrode was fabricated, effectively preventing direct contact between BiVO 4 (BVO) and the electrolyte, thereby suppressing the photocorrosion issues. Meanwhile, [Fe(CN) 6 ] 3- /[Fe(CN) 6 ] 4- and Br - /Br 3- (Fe-Br) redox pairs with high redox reversibility were used in the SRFB system. The designed PBVO Fe-Br SRFB achieved ultra-long stability and a sustained photocurrent for up to 50 h. Furthermore, the effectiveness of the charge transfer pathway in the PBVO electrode within the Fe-Br SRFB was verified, providing insights into the design of SRFBs.
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APPLIED CATALYSIS B-ENVIRONMENTAL
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2022
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IF 24.319
Xiao Yu,Mengyi Shi,Yixuan Fan,Lixia Yang,Jie Zhang,Wei Liu,Weili Dai,Shuqu Zhang,Lei Zhou,Xubiao Luo,Shenglian Luo
Mn 2 O 3 is an exceptional earth-abundant mineral that has been extensively applied in catalytic oxidation because of the strong redox couples like Mn 3+ /Mn 2+ and Mn 4+ /Mn 3+ exposed on Mn 2 O 3 surface. Herein, the catalytic activity of Mn 2 O 3 in photothermal degradation of toluene was regulated by halogens including F - , Cl -, and Br - . As the electronegativity ordered in F (3.98) > O (3.44) > Cl (3.16) > Br (2.96), F - doped Mn 2 O 3 overperforms Cl - doped and Br - doped Mn 2 O 3 in decomposing toluene. DFT theoretical calculation illustrates that F - attracts the shared electrons from Mn to itself, the deviated charge center stretches the adjacent Mn-O bonds and boosts the generation of abundant oxygen vacancies, helping to strengthen the catalytic activity of Mn 2 O 3 . Conversely, Mn-O bonds are shortened by Cl - and Br - that have lower electronegativity than O. The multiple electrons circling Cl - and Br - push Mn towards O and squeeze Mn-O bonds, resulting in the formation of passivated Mn 2 O 3 . In conjunction with Mn redox couples and oxygen vacancies, 99% of 400 ppm toluene can be eliminated by F - doped Mn 2 O 3 , corresponding mineralization rate is high up to 95.8%.
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INORGANIC CHEMISTRY COMMUNICATIONS
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2025
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IF 5.4
Jianwei Dao,Liang Yang,Zhihao Jiang,Zihao Han,Tiqin Wei
Narrow-band red inorganic phosphors excited by near-ultraviolet (n-UV) light have significant application potential in the manufacture of white light-emitting diodes (LEDs) with high R9 index. Novel near-UV-excitable Eu 3+ doped K 3 Ca 2 (SO 4 ) 3 × (X = F, Cl, Br) halosulphate phosphors were synthesized via high-temperature solid-state reaction method. By modifying the non-activating ions in the host matrix, the luminescence properties of Eu 3+ were effectively enhanced across various matrices, thereby optimizing the performance of this series of phosphors. As-prepared phosphors can be activated under 397 nm excitation and emit red light at 619 nm, corresponding to 5 D 0 → 7 F 2 transitions of Eu 3+ . Optimization of the doping concentration revealed that the optimal Eu 3+ concentration for different host matrices is 0.13. Notably, the K 3 Ca 2 (SO 4 ) 3 F host matrix doped with Eu 3+ exhibits stronger emission intensity and better performance. The K 3 Ca 2 (SO 4 ) 3 F:0.13Eu 3+ phosphor exhibited long fluorescence lifetime of 0.42 ms and high color purity of 92.25 %. The emission intensity of K 3 Ca 2 (SO 4 ) 3 F:0.13Eu 3+ at 423 K can retain 89.5 % of its value at room temperature. A white LEDs device was fabricated by mixing and encapsulating K 3 Ca 2 (SO 4 ) 3 F:0.13Eu 3+ phosphor with commercial BaMgAl 10 O 17 :Eu 2+ blue and (Ba, Sr) 2 SiO 4 :Eu 2+ green phosphors onto 397 nm n-UV InGaN chip. The device emits bright white light and exhibits high color rendering index (Ra = 79.9, R9 = 86.5) and a suitable correlated color temperature (CCT = 5915 K) at 50 mA drive current. The results suggest that this work provides new assistance in achieving high color rendering white LEDs excited by n-UV light.
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Frontiers in Pharmacology
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2022
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IF 5.988
Dong Zhen,Tang Shu-sheng,Ma Xiao-lan,Tan Bin,Tang Zhao-shan,Li Chang-hong,Yang Zi-hui,Zeng Jian-guo
The protopine alkaloids are widely distributed within the opium poppy family and have a wide range of pharmacological effects. MPTA is a product of the protopine total alkaloids extracted from the Macleaya cordata (Willd.) R. Br. Previously, we reported good anti-inflammatory activity of MPTA as well as oral acute and sub-chronic toxicity studies in rats. In order to perform a systematic toxicological safety assessment of MPTA, oral acute toxicity, genotoxicity (bone marrow cell chromosome aberration test, sperm abnormality test, bone marrow cell micronucleus test, and rat teratogenicity test), and chronic toxicity in mice were performed in this study. In the oral acute toxicity test, the LD50 in ICR mice was 481.99 mg/kg, with 95% confidence limits ranging from 404.27 to 574.70 mg/kg. All three mutagenicity tests tested negative in the range of 60.25–241.00 mg/kg. The results of the teratogenicity test in rats showed no reproductive or embryonic developmental toxicity at only 7.53 mg/kg, which can be considered as a no observed effect level (NOEL) for the teratogenicity test. Therefore, MPTA is safe for use at the doses tested, but attention should be paid to the potential risk to pregnant animals and the safety evaluation and toxicity mechanisms in target animals should be further investigated.
研究领域:
毒理学
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药理学
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遗传学
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JOURNAL OF CHEMICAL AND ENGINEERING DATA
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2019
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IF 2.298
Yongmei Xuan,Xianyu Ding,Neng Gao,Yaqi Ding,Xin Meng,Guangming Chen
1-Ethyl-3-methylimidazolium chlorine ([Emim]Cl) and 1-ethyl-3-methylimidazolium bromide ([Emim]Br) as an additive to working fluid [lithium bromide aqueous solution (H2O/LiBr) and lithium chloride aqueous solution (H2O/LiCl)] of absorption cycles were proposed. The vapor pressure of H2O + LiCl + [Emim]Cl (mass ratio LiCl/[Emim]Cl = 2) in the temperature from 314.79 to 435.48 K, H2O + LiCl + [Emim]Br (mass ratio LiCl/[Emim]Br = 2) in the temperature from 317.62 to 431.27 K, and H2O + LiBr + [Emim]Cl (mass ratio LiBr/[Emim]Cl = 2) in the temperature from 303.10 to 409.91 K was measured by the boiling point method. The mass fractions of the absorbent were from 0.30 to 0.60. The experimental data were regressed using the Antoine-type equation, and the average absolute relative deviation (AARD %) between the experimental data and calculated values of three systems was 0.44, 0.51, and 0.54%. Compared with that of the previously reported ionic liquids, ([Emim]Ac) as an absorbent for LiBr + H2O, vapor pressure of these four systems follows the order LiCl + [Emim]Cl + H2O < LiCl + [Emim]Br + H2O < LiBr + [Emim]Cl + H2O < LiBr + [Emim]Ac + H2O. The proposed ternary systems have better water affinity and can be promising alternative working fluids in the absorption cooling system.
研究领域:
化学工程
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热力学
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高影响因子
ACS Applied Materials & Interfaces
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2025
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IF 8.2
Yuhuan Lin,Jiayi Li,Jiayu Zheng,Jun Shao,Ming Wu,Yulin Liu,Ziqiao Wu,Jiandong Fan,Wenzhe Li
Cesium-based all-inorganic lead-halide perovskites CsPbX3 (X = I, Br, Cl) have emerged as highly promising optoelectronic materials with a wide bandgap, which are commonly utilized in tandem solar cells. However, the I–Br hybrid CsPbI3–xBrx perovskites still face stability issues such as halide segregation-induced phase transition and decomposition under ultraviolet or high-temperature conditions. We synthesize a series of single crystals DMAPbI3–xBrx (x = 0.1, 0.15, 0.2, 0.3, 0.6), featuring an I–Br ordered distribution. By introducing the crystal intermediate into the perovskite precursor, we successfully obtained high-quality CsPbI3–xBrx thin films, exhibiting high stabilities and low trap state density. The formation kinetics of the high-quality perovskite thin films are in situ studied and the possible reaction mechanisms are proposed. Benefiting from this approach, the solar cells have an improved photoelectric conversion efficiency and significantly enhanced thermal stability. This method is proven to be feasible and innovatively offers a new strategy for the continuous development of mixed-halide perovskite solar cells.
研究领域:
材料科学
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光伏技术
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钙钛矿太阳能电池
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晶体工程
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光电子学
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