JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2025
·Vol. 36
·期 3
·1-12
·
IF 2.8
Wang Zhenxing,Luo Qingsong,Huang Yiheng,Chen Yan,Wang Yimu,Feng Changhao
The sensitive and rapid detection of n-butanol gas is crucial for ensuring industrial safety, environmental protection, and biological health. In this study, we employed electrospinning to fabricate a series of CuBi 2 O 4 nanofibers and nanotubes, followed by thorough characterization and analysis of their structural and functional features using XRD, FE-SEM, TEM, and XPS techniques. The gas-sensing performance demonstrates that CuBi 2 O 4 nanotubes (CBO-500) exhibit an exceptionally rapid response to n-butanol, highlighting their potential for use in high-sensitivity n-butanol sensors. The sensor exhibited a response of 12.30–10 ppm n-butanol at 150 °C, with a rapid response time of 2 s and a recovery time of 41 s. Furthermore, the sensors based on CBO-500 nanotubes exhibited excellent selective. In addition, this study elucidates the underlying mechanisms responsible for the gas-sensing properties of CuBi 2 O 4 nanotubes toward n-butanol.
研究领域:
材料科学
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环境科学
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传感器技术
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产品关联
DOI
高影响因子
Polymers
·
2015
·Vol. 7
·期 9
·1850-1870
·
IF 3.681
Jiaojiao Xu,Beihua Xu,Dan Shou,Xiaojing Xia,Ying Hu
Chronic intracellular infections caused by drug-resistant pathogens pose a challenge to the treatment of chronic osteomyelitis. Such treatment requires an intracellular delivery system for the sustained release of antibiotics such as vancomycin (VCM), which is an antibiotic of last resort used against many clinically resistant bacteria. In this work, we report VCM-loadedN-trimethyl chitosan (TMC) nanoparticles and their potential application for drug delivery. The results showed that the prepared nanoparticles were predominantly spherical in shape with an average particle diameter of 220 nm, a positive zeta potential, and a loading efficiency of 73.65% ± 1.83%. Furthermore, their drug release profile followed the Higuchi model for sustained release, with non-Fickian diffusion. Over a 24-h period, 6.51% ± 0.58% of the drug within the optimized nanoparticles was released.In vitrocytology showed that osteoblasts (OBs) exhibited higher alkaline phosphatase activity (ALP) after exposure to TMC nanoparticle material. Furthermore, TMC nanoparticles increased the uptake of water-soluble quantum dots (QDs) by OBs, and both nanoparticles and VCM/TMC mixtures improved OB proliferative activity. We also investigated the minimum inhibitory concentration (MIC, 60 μg/mL), half maximal inhibitory concentration (IC50, 48.47 μg/mL), diameter of inhibition zone (DIZ, 1.050 cm), and turbidimetric (TB) assay of nanoparticles. All data demonstrated that VCM/TMC nanoparticles had excellent antibacterial activity against the Gram-positive bacteriumStaphylococcus aureus. These findings suggest that VCM-loaded TMC nanoparticles have good potential for the sustained delivery of antibiotics to bone infections.Keywords:vancomycin (VCM);N-trimethyl chitosan (TMC);intracellular infections;nanoparticles
研究领域:
药学
·
生物医学工程
·
微生物学
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产品关联
DOI
高影响因子
JOURNAL OF POWER SOURCES
·
2025
·
IF 7.9
Huiying Cheng,Jingchang Sun,Siwen Liu,Furong Cao,Liuting Shan,Zijiang Yang,Xiaofan Cui,Jiaxu Zhao,Zhen Qiao,Qiuju Feng
Low-grade heat (<100 °C) is abundant and ubiquitous in the environment, and the recovery of low-grade heat energy will be of great significance for the energy supply and the improvement of the environment. Low-cost and effective technologies for transforming low-grade heat into electricity are urgently needed. Thermocell (TEC) based on REDOX couples has become a promising technology for low-grade heat harvesting due to its advantages of low cost, scalability, and intrinsic high thermopower. To enhance its performance, different types of TECs need to incorporate various additives into the REDOX couples. However, there is currently no identical additive that effectively enhances the performance of both P-type and N-type TECs. In this paper, carboxylated chitosan is used as an identical additive, resulting in an increase in the Seebeck coefficient of P-type and N-type TECs by 115.33 % and 53.25 %, respectively. Furthermore, we introduce a novel sandwich-structured packing technique featuring a configuration of Metal/PET film/Carbon felt (MPC) for TEC. This approach effectively reduces both the cost and weight of the TEC, while the MPC structure further enhances their performance. The TEC can be scaled up to power electrical devices. Our achievement provides an effective strategy for harvesting low-grade heat energy.
研究领域:
能源材料
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环境科学
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产品关联
DOI
高影响因子
CELLULOSE
·
2024
·Vol. 31
·期 8
·5263-5280
·
IF 4.9
Han Qiuxia,Xu Yanmeng,Zhao Qian,Wang Shiwei,Zhang Chunzhe,Zhang Qiang,Wang Fei,Bai Yu,Chen Yong
The study reports a tactic for superior antibacterial performance on cotton via synergism of complementary functionalities of quaternary ammonium salt and malonylurea-based N -chloramine combined in a silane. Knoevenagel Condensation between 4-(chloromethyl)benzaldehyde and malonylurea formed a product whose chloromethyl group was used to quaternize tertiary amine of N , N -dimethylethanolamine. The O − H of the quaternization product was subsequently alcoholyzed with Si − H of trimethoxysilane. The methoxysilyl groups of the alcoholysis silane were hydrolyzed to silanol ones that condensed with either their own kind or hydroxy groups of cellulose to polymerize into a crosslinked polysiloxane finishing on cotton. Upon chlorination of malonylurea-based N − H bonds, each repeating unit of the polysiloxane has one quaternary ammonium salt and two imide N -chloramine sites. Antibacterial assays against Staphylococcus aureus and Escherichia coli proved that the synergism of quaternary ammonium salt and N -chloramine, a higher efficacy and a broader spectrum arising from their complementary elimination mechanisms and physiochemical features. Biocidal stability and rechargeability of the polysiloxane finishing were both promising due to the robust and hydrophobicity of silicone backbone and the sturdy cyclic N -chloramine. This research presented a general approach for generation of super biocidability on substrates that can react with hydroxy group using silanes to carry complementary functionalities. Graphical abstract
研究领域:
材料科学
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纺织工程
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生物医学
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DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
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2015
·Vol. 132
·期 43
·
IF 1.768
Xiaoqin Chen,Zuliang Liu,Weiwei Cao,Chunyan Yong,Xiaodong Xing
A viable method for coating of cellulose fiber with quaternarized N-halamine is reported in this article. The use of quaternary ammonium salt group in combination with N-halamine group can reinforce the antibacterial activity. The chemical structure of as-synthesized N-halamine precursor 4-(Bromo-acetic acid methylester)-4-ethyl-2- oxazolidinone (BEO) was characterized by 1 H-NMR. The cellulose fibers were characterized by Fourier transform infrared spectra and X-ray photoelectron spectra. The spectra data confirmed that the quaternarized N-halamine-grafted cellulose fibers were successfully obtained. The antibacterial properties of functional fibers were challenged with both Gram positive and Gram negative bacteria. The antibacterial tests and showed that the as-prepared antibacterial cellulose fibers exhibited powerful and rapid bactericidal performance against both Gram negative E. coli and Gram positive S. aureus . © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132 , 42702.
研究领域:
材料科学
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微生物学
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产品关联
DOI
高影响因子
FUEL
·
2016
·
IF 3.611
Erjiang Hu,Hongzhen Tian,Xinyi Zhang,Xiaotian Li,Zuohua Huang
N -butanol is a promising alternative fuel for automobile whose explosion characteristics should be a major focus before widely used. Unfortunately, limit researches focusing on its explosion characteristics have been launched until now. In this study, the effects of n -butanol addition on the explosive characteristics of iso-octane-air mixtures with various concentrations and initial pressures and temperatures were experimentally investigated and analysed on the basis of combustion pressure history. The explosion pressure p exp and the maximum explosion pressure p max , the maximum rate of pressure rise ( d p / d t ) max , the deflagration index K G , and combustion duration t c as well as flame development period t d , were examined. Results show that with the increase of n -butanol blending ratio, explosion pressure does not change, while explosion duration is decreased, so the maximum rate of pressure rise is increased. It was found that pressure curves of rich mixtures oscillate in the vicinity of pressure peak at elevated pressures, and the pressure oscillation greatly shortens the explosion duration and increases the maximum rate of pressure rise. In addition, with the increase of n -butanol blending ratio, the pressure oscillation intensity is decreased.
研究领域:
能源科学
·
化学工程
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产品关联
DOI
高影响因子
BIOMACROMOLECULES
·
2021
·
IF 6.988
Botuo Zheng,Songyi Xu,Xufeng Ni,Jun Ling
Polymerization of N-substituted glycine N-thiocarboxyanhydrides (NNTAs) is a promising pathway to prepare functional polypeptoids benefiting from their tolerance to nucleophilic impurities. However, controlled NNTA polymerization is hard to achieve in amide polar solvents, including N,N-dimethylacetamide (DMAc), N,N-dimethylformamide (DMF), and N-methyl pyrrolidone (NMP), the only aprotic solvents for many biomacromolecules and polypeptoids. In the present work, we successfully achieve controlled NNTA polymerization in amide polar solvents by adding acetic acid as a promoter. The promotion is applied to the polymerization of sarcosine NTA, N-ethyl glycine NTA, and N-butyl glycine NTA. DMAc, DMF, and NMP are suitable solvents to prepare polypeptoids with designable molecular weights and low dispersities (1.06–1.21). The polysarcosines with high molecular weights are prepared up to 35.2 kg/mol. A kinetic investigation quantitatively reveals that the presence of acetic acid not only accelerates the polymerization, but also suppresses H2S-catalyzed decomposition of NNTAs by decreasing the concentration of H2S dissolved in polar solvents. Benzoic acid is also able to promote the polymerization, while trifluoroacetic acid, phosphoric acid, and phenol are not appropriate promoters. The moderate acidity of acids is essential. l-Methionine, l-tryptophan, and l-phenylalanine, which are dissolved in DMF, initiate the controlled polymerization of sarcosine-NTA in the presence of acetic acid and introduce functional end groups to polysarcosines quantitatively. In DMAc, hydrophilic vancomycin is grafted by poly(N-butyl glycine). The amphiphilic product dissolves in dichloromethane and stabilizes water-in-oil emulsion.
研究领域:
高分子化学
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材料科学
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生物技术
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DOI
高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2011
·
IF 2.546
Lei Li,Xiaoying Du,Jianping Deng,Wantai Yang
Optically active macroporous poly( N -isopropylacrylamide) (PNIPAM) hydrogels were synthesized via free radical copolymerization of NIPAM, helical macromonomer, and cross-linker N , N ′-methylenebisacrylamide. The helical macromonomer not only contained catechol groups but also vinyl groups in side chains. Polyethylene glycols were used as pore-forming agent to give rise to macroporous structures in the optically active hydrogels. The hydrogels were characterized by FT-IR, SEM, DSC , swelling ratio and circular dichroism spectra analyses and exhibited the expected optical activity and macroporous architectures. The chiral resolution tests demonstrated the preferential adsorption of the hydrogels towards d -tryptophan and d -phenylalanine in the corresponding two amino acid enantiomers .
研究领域:
材料科学
·
高分子化学
·
生物化学
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DOI
高影响因子
MONATSHEFTE FUR CHEMIE
·
2023
·Vol. 154
·期 10
·1189-1195
·
IF 1.8
Wang Peng,Shi Huibing,Feng Baolin,Zhao Deming,Wu Haigang
The Ru-catalyzed highly selective alkoxycarbonylation of allenes with aliphatic alcohols (also as solvent) allow to produce useful α , β -unsaturated esters in good to excellent yields at 70 °C. Efficient regioselectivity could be controlled in the presence of N-ligands while the P-ligands had no influence on the conversion of substrates and the chemo/regioselectivity of target products. By involving N-ligand 4,7-dimethyl-1,10-phenanthroline in the catalytic system, α , β -unsaturated esters were obtained with high conversion and chemo/regioselectivity (conversion up to 99%, chemical selectivity up to 99%, regioselectivity of branched ester/linear ester up to 89/11). Graphical abstract
研究领域:
有机化学
·
催化化学
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DOI
高影响因子
CHROMATOGRAPHIA
·
2025
·
IF 1.3
Lou Doudou,Zhu Yuan,Fan Jingke,Fan Lin,Zhu Qingfu,Lu Yihong,Zhao Shuqiang
N-glycosylation heterogeneity has a significant impact on the clinical safety, efficacy, pharmacokinetics (PK), and pharmacodynamics of monoclonal antibody (mAb) drugs, thus becoming a critical quality attribute (CQA) of great concern. In the registration quality standards for bevacizumab produced by different manufacturers, either lacking supervision of N-glycosylation or the detection methods and criteria vary greatly among manufacturers, leading to compromised comparability of results. Besides, the existing quality control system pays insufficient attention to the correlation between glyco-relevant physicochemical properties and glycosylated modification. In this study, a standardized hydrophilic interaction liquid chromatography-fluorescence detection (HILIC-FLD) N-glycan profiling method was developed, which had been proven to be more time-saving and easier to operate and was used for the parallel analysis of N-glycan profiles in bevacizumab products provided by 8 different manufacturers. We also paid attention to the glycosylation-related CQAs including charge heterogeneity, isoelectric point, non-glycosylated heavy chain (NGHC) and aggregates. Results revealed obvious difference in N-glycosylation, NGHC and aggregates among manufacturers. Among all the mAbs, the abundance of major glycoforms showed similar order yet the percentage of the same glycoform varies greatly. In summary, the standardized method could offer a reliable, efficient and practical approach for the parallel analysis and comparison of glycosylation and related CQA heterogeneity among manufacturers, providing a reference for more effective quality control of mAb drugs.
研究领域:
生物化学
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药物分析
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分子生物学
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产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2023
·
IF 9.9
Yuanrong Zhang,Shuaitao Li,Xun Hu,Yanfen Fang,Ran Duan,Qifeng Chen
The construction of heterointerface in photocatalyst is an efficient approach to boost the separation and utilization efficiency of charge carriers, which is challenging and crucial in photocatalysis. Here, the construction of melon-structured carbon nitride/ N -doped WO 3 (MCN/NW x ) heterojunction photocatalyst was achieved by a method of prealcoholysis combined with thermal polymerization, where N -doping of WO 3 was achieved in-situ in the formation of heterojunction. The promoted charge separation efficiency was realized through the charge transfer from the conduction band of N -doped WO 3 to the valence band of the MCN. Density functional theory calculation results showed that the formation of the W–N heteroatom-interface led to the increase of density of states at the heterointerface and decrease of the band gap. The MCN/NW x nanocomposite featured a metallic band structure of the nanocomposite photocatalysts, resulting in the enhanced photocatalytic activity . The photocatalytic hydrogen evolution activity of the MCN/NW 2 was enhanced about 2.5 times than that of MCN. This research provides a novel insight into the construction of a novel heteroatom-junction that boosts the separation efficiency of charge carriers, and thereby improves the photocatalytic activity.
研究领域:
材料科学
·
能源科学
✓ 已验证
DOI
高影响因子
POLYMER
·
2025
·
IF 4.5
Xiaoqiang Xue,Yangjing Chen,Xuepei Miao,Jian Liu,Yi Ding,Yuheng Zhang,Yunkai Sun,Wenyan Huang,Qimin Jiang,Hongting Pu
Environmentally sensitive polymer materials exhibit diverse properties due to their ability to respond to external environmental changes such as light, temperature, pH, and et al. These responses lead to corresponding alterations in their structure or state, resulting in unexpected performance. In this study, azo pyridine groups were introduced into the end groups and side chains of PNIPAM to synthesize two distinct polymer structures (PNIPAM-AZO and P (NIPAM- co -PAZO- co -OEGMA). This integration enables the polymers to respond to multiple stimuli, including temperature, light, pH, and gas (CO 2 ). A comprehensive investigation of the properties of these multi-responsive polymer materials was conducted. The findings reveal that the presence of azo pyridine units enables both polymers to modulate the (lower critical solution temperature) LCST of PNIPAM through UV, pH, and CO 2 , with a maximum temperature adjustment of 13 °C when CO 2 is introduced. This modulation range is influenced by the azo pyridine content in the polymer. Notably, when azo pyridine is present only at the polymer end group, the maximum LCST regulation range is limited to 3 °C. Moreover, the LCST of the two polymers can also be adjusted by pH. In the presence of carbonate ions, the protonation of azo pyridine by carbonic acid increases the solubility of the polymer and enhances the LCST. Introducing argon gas removes CO 2 , thereby restoring the polymer's solubility and LCST to their neutral condition levels. By alternately introducing CO 2 and argon gas, the LCST of the polymer exhibits cyclic changes.
研究领域:
材料科学
·
高分子化学
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产品关联
DOI
高影响因子
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