LWT-FOOD SCIENCE AND TECHNOLOGY
·
2025
·
IF 6.6
Lihua Zhang,Yuli Ning,Yingying Xin,Yinjiao Wei,Xinfang Liu,Bakht Ramin Shah,Xiaofan Zhang,Wei Xu
This study investigates the effects and underlying mechanisms of freeze-thawing on the mechanical properties of Pickering emulsion gels composed of konjac glucomannan/κ-carrageenan (KGM/CRG) induced by K 2 CO 3 . The results showed that as the number of freeze-thaw cycles increased, syneresis and water loss during the squeezing of the gels significantly rose, while their shear strength gradually increased. After two freeze-thaw cycles, the gel exhibited maximum hardness. Microstructural analysis revealed that ice crystals disrupted the original gel network, leading to the aggregation of oil droplets and the dissipation of water. During freezing, the crystallization of water enhanced interactions among polysaccharide molecules, resulting in a more robust and denser KGM-CRG network. X-ray diffraction analysis confirmed an increase in the crystallinity of the gel following freeze-thaw cycle treatment. Furthermore, compared to fresh samples, the freeze-thawed emulsion gels displayed higher storage and loss modulus. These findings suggest that Pickering emulsion gels show increased mechanical properties after treatment. Additionally, this study illustrated the potential mechanisms by which freeze-thaw treatment modifies the microstructure of Pickering emulsion gels and influences their gel properties, providing a theoretical foundation for the design of emulsion-gel foods through freeze-thaw cycle treatment.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Irfan Ijaz,Aysha Bukhari,Ezaz Gilani,Ammara Nazir,Hina Zain,Attia Shaheen,Mohammed Rafi Shaik,Mujeeb Khan,Mohamed E. Assal
A rising quantity of drugs has been discharged into the aquatic environment, posing a substantial hazard to public health. In the current work, a novel hydrogel (i.Carr@Bent@PTC), comprised of iota-carrageenan, bentonite, and 4-phenyl-3-thiosemicarbazide, was successfully prepared. The introduction of 4-phenyl-3-thiosemicarbazide and bentonite in iota-carrageenan significantly increased the mechanical strength of iota-carrageenan hydrogel and improved its degree of swelling, which can be attributed to the hydrophilic properties of PTC and Bent. The recorded contact angle was 70.8°, 59.1°, 53.9°, and 34.6° for pristine i.Carr, i.Carr@Bent, and i.Carr@Bent@PTC, respectively. The low contact angle measurement of the Bent and PTC loaded-i.Carr hydrogel was attributed to the hydrophilic Bent and PTC. The ternary i.Carr@Bent@PTC hydrogel demonstrated broad pH adaptability and excellent adsorption capacities for sulfamethoxazole (SMX) and losartan potassium (LP), i.e., 467.61 mg. g −1 and 274.43 mg. g −1 at 298.15 K, respectively. The pseudo-first-order (PSO) model provided a better fit for the adsorption kinetics . The adsorption of SMX and LP can be better explained by employing the Sips and Langmuir isotherm models. As revealed by XPS and FTIR investigations, π-π stacking, complexation, electrostatic interaction , and hydrogen bonding were primarily involved in the adsorption mechanisms.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Xin Liu,Jingkun Zhao,Kai Xia,Tao Liu,Jiakun Zhang,Xiaodong Zhang
Future food packaging trends are shifting toward degradable and even edible materials developed from natural polysaccharides, in order to reduce the pollution caused by synthetic polymers. In this article, a series of dispersion systems of agar (AG), κ-carrageenan (KC), cellulose nanofiber (CNF), as well as their composite systems were systematically prepared, and their corresponding physicochemical properties and application in food packaging film were investigated. The results showed that the intermolecular interactions between AG and KC molecules led to the formation of AG double helix, AG/KC double helix, and KC double helix in AG/KC composite system. Then the double helix structures interleaved with each other during the further cooling process, and new aggregate structures should be formed. Similar phenomena occurred in AG/CNF and KC/CNF composite systems. The optimum preparation technology of Ca 2+ -AG/KC/CNF edible nanocomposite film was obtained by preliminary single-factor experiment and response surface methodology (RSM). Compared with pure polysaccharide films, two-component composite films, and some plastic films, the prepared nanocomposite film possessed excellent optical properties, mechanical properties, good thermal stability and freshness retention performance. The results showed that the new Ca 2+ -AG/KC/CNF edible nanocomposite film had great potential for food packaging application.
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Gels
·
2025
·Vol. 11
·期 12
·961
·
IF 5.3
Weifeng Chen,Guanchen Wu,Lanlan Zhang,Lihua Zhang,Bakht Ramin Shah,Wei Xu
The paper explored the impact of sodium caseinate (CAS) emulsion on the freeze–thaw stability of konjac glucomannan (KGM)/κ-carrageenan (KC) composite gels. It found that the emulsion and KGM both increased the viscoelasticity of the composite gel, giving it a greater elastic stress. Emulsion addition enhanced the water-holding capacity (WHC) of the KC gel from 72.36% to 89.34%. KGM addition further improved WHC to 97.54%. The hardness of the emulsion KGM/KC gel reached 9.35 N, while the values were essentially not affected by freeze–thaw. This study shows that CAS emulsion, especially under the regulation of KGM and KC, can improve the freeze–thaw stability of the gel system. The results show that emulsion has great potential in regulating the physical and textural properties of multiphase gels. The emulsion coupling method could effectively enhance the freeze–thaw stability of gels, which may provide a new strategy for the development of frozen multiphase gel foods.
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Frontiers in Nutrition
·
2025
·
IF 5.1
Jinpeng Gong,Yuhan Zhang,Tao Jie,Tao Huang,Yupeng Ma,Hao Chen,Jing Gan,Junbo Ge
Osteoporosis is a widespread skeletal disorder associated with reduced bone formation and increased fracture risk. Peptide-based therapeutics offer demonstrate anabolic potential for osteoporosis management but are limited by instability and rapid clearance. In this study, a dual-network hydrogel composed of fish gelatin (FG) and κ-carrageenan (κ-CG) was developed as a biocompatible carrier for a soybean-derived osteogenic peptide (SOP). The FG/κ-CG system exhibited provided mechanical integrity, hydration balance, and thermal stability, thereby enabling sustained peptide protection and controlled release. In a glucocorticoid-induced zebrafish osteoporosis model, oral administration of the SOP-loaded gel effectively restored bone mineralization to a level comparable with alendronate treatment. These findings suggest that the FG/κ-CG-SOP hydrogel provides a stable and bioactive platform for osteogenic peptide delivery and represents a promising nutritional or therapeutic approach for osteoporosis management.
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Biomedical Physics & Engineering Express
·
2025
·Vol. 11
·期 4
·045008
·
IF 1.6
Yinjian Hua,Jun Zeng,Sai He,Yuzhe Zhang,Longtai Wang,Linrong Xiao,Guohua Jiang
In this study, isosorbide mononitrate (ISMN)-loaded liposomes (ISMN-LNPs) were encapsulated within an injectable composite hydrogel that consisted of κ-Carrageenan (κ-Car), hyaluronic acid (HA), and tannic acid (TA). The fabricated composite hydrogel exhibited exceptional reactive oxygen species (ROS) scavenging capabilities to enhance cell migration. Upon injection of the ISMN-LNP-loaded composite hydrogel into the injured hearts of rats, significant improvements in cardiac function could be observed after treatment. Furthermore, Masson's staining results revealed that the injectable hydrogel system reduced myocardial infarct size and increased left ventricular wall thickness post-myocardial infarction. Immunofluorescence staining results indicated the upregulating expression of vascular hemophilic factor (VWF) and α-actinin, suggesting that the injectable hydrogel system to promote vascular proliferation and enhance cardiac systolic and diastolic function following myocardial infarction.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2021
·
IF 6.953
Qian Zhang,Luping Gu,Yujie Su,Cuihua Chang,Yanjun Yang,Junhua Li
The aim of the present study was to develop soy protein isolate (SPI) and κ-carrageenan (KC) composite hydrogels as a delivery system for hydrophilic compounds. The pigment of monascus yellow was used as a model. A systematic study was performed to characterize the rheological, textural, microstructural properties and in vitro digestion release profile of monascus yellow of the composite gels. The results of power law modeling, electrophoresis patterns and fourier transform infrared spectroscopy (FTIR) confirmed that non-covalent interactions were involved in the formation of SPI/KC composite hydrogels. Compared to pure κ-carrageenan hydrogels, the incorporation of SPI could promote the formation of tougher, more uniform and compact composite gels with sustained-release property. In addition, the release behaviors of monascus yellow entrapped in the hydrogel network can be well described by the Ritger-Peppas mathematical model. Overall, our study provided a promising strategy to enhance the sustained release performance of hydrogels in digestive conditions.
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JOURNAL OF FOOD SCIENCE
·
2021
·Vol. 87
·期 1
·302-311
·
IF 3.167
Yi-Nan Du,Shan Xue,Jia-Nan Yan,Xin-Yu Jiang,Hai-Tao Wu
The objective of this study was to investigate the properties of ternary composite gel of scallop ( Patinopecten yessoensis ) protein hydrolysates (SMGHs)/κ-carrageenan (KC)/xanthan gum (XG). The rheological properties, moisture-distribution, molecular structure, and microstructure of SMGNs/KC/XG gels were analyzed. The results showed that the G ′ value, melting temperature, and water holding capacity of SMGHs/KC/XG were higher than those of SMGHs, SMGHs/KC, and SMGHs/XG. FTIR spectrum showed the generation of hydrogen bonds between SMGHs and KC/XG, and the carboxylic acid group of XG interacts with SMGHs. Moreover, the cryo-SEM results showed that SMGHs/KC/XG exhibited a tighter, smoother, and more aggregated microstructure than those of SMGHs, SMGHs/KC, and SMGHs/XG. These results indicate that the gel and microstructural properties of SMGHs are significantly improved by addition of KC and XG, and SMGHs/KC/XG has potential to be used as functional hydrogels for food, pharmaceutical, and biomedical applications. Practical Application Scallop ( Patinopecten yessoensis ) male gonads are rich in protein and usually regarded as byproducts during adductor processing. Because of its gelation properties, scallop male gonads have potential to be used as functional hydrogels for food. The SMGHs/KC/XG ternary composite gel showed excellent gel properties, which would be potentially applied in delivery system in food and biological fields. Further study is undergoing to apply SMGHs/KC/XG to embed bioactive compounds, such as curcumin and β-carotene.
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FOOD CHEMISTRY
·
2026
·
IF 10.4
Yin-Yin Lv,Tian-Qi Zhou,Xian-Hao Zhang,Miao-Miao Luo,Yi-Nan Du,Ce Wang,Bin Lai,Da-Ming Fan,Na-Na Zhang,Heng Jiang,Jia-Nan Yan,Hai-Tao Wu
Composite gels were constructed by sea bass powder (SBP) and κ-Carrageenan (κ-C). • κ-C improved the shear resistance of SBP/κ-C composite gels under LAOS. • The SBP/κ-C composite systems can be classified as level 4–6 food. • The introduction of κ-C enhanced water retention ability and network density of SBP. • Hydrogen bonds and hydrophobic interactions dominate the combination of SBP/κ-C composite gels. The effect of κ-carrageenan (κ-C, 2–6 mg/mL) on the gelling properties of sea bass powder (SBP) were investigated. Adding κ-C increased storage modulus of SBP by 10- to 61-folds and raised the sol-gel transition temperature. Nonlinear rheological analysis characterized the SBP/κ-C gels by weak strain overshoot and intracycle shear thinning behavior. According to the International Dysphagia Diet Standardization Initiative (IDDSI) framework, the SBP/κ-C gels were classified as level 4–6 foods. Moreover, the T 23 relaxation time of the SBP/κ-C gels migrated from 666.99 ms to 554.27 ms. Correspondingly, the network structures of SBP became denser and uniform after adding κ-C. In addition, a blue shift in hydroxyl bands confirmed the formation of hydrogen bonds between SBP and κ-C. Adding κ-C increased the proportions of β-sheets and random coil, but sacrificed the α-helix part of SBP. These results provided a theoretical basis for the development of marine-derived soft gel-based foods. Download: Download high-res image (427KB) Download: Download full-size image
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2023
·Vol. 30
·期 17
·49301-49313
·
IF 5.8
Abd El-Monaem Eman M.,Eltaweil Abdelazeem S.,El-Subruiti Gehan M.,Mohy-Eldin Mohamed S.,Omer Ahmed M.
Water pollution is a dreadful affair that has incessantly aggravated, exposing our planet to danger. In particular, the persistent nitro aromatic compound like nitrophenols causes anxiety to the researchers due to their hazardous impacts, excessive usage, and removal difficulty. For this purpose, a novel multi-featured composite was constructed based on κ-Carrageenan (κ-Carr), MOF (MIL-125(Ti)), and magnetic Fe 3 O 4 for efficient adsorptive removal of o-nitrophenol (o-NP). Interestingly, BET measurements revealed the high surface area of Fe 3 O 4 -κ-Carr/MIL-125(Ti) of about 163.27 m 2 /g, while VSM showed its excellent magnetic property (20.34 emu/g). The comparison study pointed out the synergistic effect between Fe 3 O 4 , κ-Carr, and MIL-125(Ti), forming a composite with an excellent adsorption performance toward o-NP. The adsorption data obeyed pseudo-second-order kinetic model, and Freundlich isotherm model was better fitted than Langmuir and Temkin. Furthermore, Langmuir verified the supreme adsorption capacity of o-NP onto Fe 3 O 4 -κ-Carr/MIL-125(Ti) since the computed q max reached 320.26 mg/g at pH 6 and 25 °C. Furthermore, the XPS results postulated that the adsorption mechanism pf o-NP proceeded via H-bonding, π - π interaction, and electron donor–acceptor interactions. Interestingly, Fe 3 O 4 -κ-Carr/MIL-125(Ti) composite retained good adsorption characteristics after reusing for five cycles, suggesting its viable applicability as an efficient, renewable, and easy-separable adsorbent for removing nitro aromatic pollutants.
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JOURNAL OF FOOD BIOCHEMISTRY
·
2022
·Vol. 46
·期 12
·e14460
·
IF 3.654
Jing Guo,Jian-Kai Tang,Bai-Fang Wang,Wen-Rui Yan,Ting Li,Xue-Jian Guo,Lei Zhang,Tao Wang,Qian-Yun Sun,Li-Wei Zhang
Forsythia suspensa (Thunb.) Vahl (Oleaceae) leaves are valuable sources of phillygenin. This study aimed to isolate phillygenin from F. suspensa leaves and examine its analgesic and anti-inflammatory effects. Phillygenin was successfully extracted and isolated from F. suspensa leaves after fermentation. Phillygenin significantly reduced the number of writhing induced by acetic acid, prolonged the latency period in the hot plate test, and inhibited the xylene-induced ear edema and carrageenan-induced paw edema in mice. IL-6, TNF-α, IL-1β, NO, and PGE 2 levels in the carrageenan-induced paw edema were notably reduced after pretreatment with phillygenin. Phillygenin significantly decreased the iNOS and COX-2 protein expressions and the IκB-α and NF-κB p65 phosphorylation. This study demonstrated that phillygenin is a potential therapeutic candidate for managing pain and inflammation-mediated disorders. The study contributes to the comprehensive development and utilization of F. suspensa leaves for economic and health care. Practical applications Phillygenin is one of the major active ingredients in Forsythia suspensa . But the content of phillygenin in F. suspensa is very low which limits its application. Phillygenin has potential pharmacological activity and anti-inflammatory properties. However, the potential effects of phillygenin on analgesic activity have not been clarified. Furthermore, the data on its anti-inflammatory activity in vivo are relatively limited. This study evaluated the analgesic activity for the first time and the acute anti-inflammatory effect of phillygenin from F. suspensa leaves by fermentation, which indicated phillygenin is a potential therapeutic candidate for managing pain and inflammation-mediated disorders.
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JOURNAL OF POLYMERS AND THE ENVIRONMENT
·
2021
·Vol. 30
·期 3
·1001-1011
·
IF 3.667
Wang Fen,Duo Tongtong,Wang Yongxin,Xiao Zhihong,Xu Airong,Liu Rukuan
In this work, a novel PEI/CG composite was fabricated via a facile one-step strategy at ambient conditions using biodegradable and highly absorbent κ -carrageenan (CG) as a matrix, polyethyleneimine (PEI) as a functional component and poly(ethylene glycol) diglycidyl ether (PGDE) for cross-linking PEI/CG. Systematic investigations were carried out to determine the optimal PEI/CG mass ratio, PGDE/PEI mass ratio and the total concentration of CG and PEI in CG/PEI/PGDE/5 wt% NaOH solution. Batch adsorption experiments have been achieved to investigate the effects of different parameters including solution pH, adsorbent dose, initial Cu 2+ concentration, solution temperature and contact time on the adsorption performance of the composite towards Cu 2+ . Interestingly, the PEI/CG composite showed efficient Cu 2+ adsorption performance. Furthermore, adsorption kinetics, thermodynamics and isotherms have also been investigated to reveal Cu 2+ adsorption behavior and mechanism by the composite during the Cu 2+ adsorption process. In addition, the PEI/CG composite after Cu 2+ adsorption was also investigated with FT-IR and EDS technique to estimate adsorbed Cu 2+ onto the composite. This work opened up new horizons for the fabrication of novel PEI composite with practical application using a facile one-step fabrication strategy.
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