EUROPEAN POLYMER JOURNAL
·
2026
·
IF 6.8
Yudong Hou,Xiaocong Deng,Chao Ma,Sheng-chao Huang,Cuifen Lu
This study reports the synthesis of a novel flame retardant (TDOPO) via a one-pot nucleophilic addition reaction, in which 3,4-Dihydroxybenzaldehyde (PH) was grafted onto 9,10-dihydro-9-oxa-10-phosphaphenanthrene 10-oxide (DOPO) at different oxidation states. The chemical structure of TDOPO was confirmed by Fourier Transform Infrared Spectroscopy (FTIR) and Nuclear Magnetic Resonance (NMR).The effects of TDOPO dosage on the flame retardancy, thermal properties, and mechanical properties of epoxy resin (EP) composites were systematically investigated and compared with those of pure epoxy resin. At a TDOPO content of 10 wt% (EP/TDOPO10), the epoxy resin composite achieved a Limiting Oxygen Index (LOI) of 33.6% and a UL-94V-0 rating, demonstrating outstanding flame retardancy. Cone calorimeter tests revealed that, compared to pure epoxy resin, the EP/TDOPO10 composite exhibited reductions of 41.0%, 18.6%, and 20.4% in peak heat release rate (PHRR), total heat release (THR), and total smoke production (TSP), respectively. These improvements are attributed to the abundant hydroxyl groups in the resorcinol structure, which promote the formation of a denser and more continuous char layer. Additionally, the phosphorus element in TDOPO catalyzes char formation, leading to a phosphorus-rich three-dimensional network char layer in the condensed phase during combustion. The substantial char residue effectively impedes heat and oxygen transfer to the underlying polymer matrix. Thus, this flame retardant imparts superior flame retardancy and mechanical properties to epoxy resins, positioning it as a promising candidate for developing functional thermoset flame retardants.
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高影响因子
BIOMACROMOLECULES
·
2026
·Vol. 27
·期 8
·5491-5504
·
IF 5.9
Liu Sihao,Zhang Chengyu,Chen Zhenyu,Chang Heng,Qi Wei,Wang Yuefei,Su Rongxin
Diabetic skin injury is a serious clinical challenge
due to impaired
healing and infection. Here, we developed a sandcastle worm-inspired
hydrogel featuring a phosphate–catechol–amine synergistic
network based on a poly(acrylic acid- co -acrylamide)
network, functionalized with dopamine-grafted cellulose nanofibers
(DA-PCNF) and quaternized chitosan (QCS), to accelerate diabetic wound
healing. The hydrogel exhibits strong tissue adhesion (78.82 ±
2.55 kPa) and broad-spectrum antibacterial activity (99.67% killing
of Escherichia coli and 99.55% killing
of Staphylococcus aureus in vitro). More importantly,
it exhibits pH-responsive swelling and adhesion behaviors, maintaining
robust adhesion under mildly acidic wound conditions while attenuating
adhesion under neutral conditions to facilitate atraumatic dressing
removal. Antioxidant assays indicated that the hydrogel exhibits scavenging
activity against various free radicals with efficiencies ranging from
30% to 40%, attributable to the catechol groups. In vivo application
of the hydrogel to infected diabetic wounds significantly accelerated
healing (99.82%, on day 12 after Pseudomonas aeruginosa -infected wound formation), with reduced inflammation and enhanced
tissue regeneration. These findings demonstrate that the catechol–nanocellulose/chitosan
polymeric hydrogel effectively overcomes adhesion, infection, and
oxidative stress barriers in diabetic wound healing, making it a promising
candidate for difficult-to-heal chronic ulcers.
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高影响因子
BIOMATERIALS
·
2014
·
IF 8.312
Hongzhi Qiao,Minjie Sun,Zhigui Su,Ying Xie,Minglei Chen,Li Zong,Yahan Gao,Huipeng Li,Jianping Qi,Qun Zhao,Xiaochen Gu,Qineng Ping
Renal fibrosis is a common progressive kidney disease, and there is a lack of efficient treatment for the condition. In this study, we designed a kidney-specific nanocomplex by forming coordination-driven assembly from catechol-derived low molecular weight chitosan (HCA-Chi), metal ions and active drug molecules. The coordination activities of various metals and ligands, cytotoxicity, immunogenicity and biodistribution of HCA-Chi were investigated. Autofluorescent doxorubicin (DOX) was selected to fabricate HCA-Chi-Cu-DOX ternary nanocomplex for investigating cellular uptake behavior, transmembrane and targeting properties. The nanodevice demonstrated satisfactory stability under normal physiological conditions and pH-responsive drug release in acidic environments. Uptake of HCA-Chi-Cu-DOX by HK-2 cells was dependent on exposure time, concentration, and temperature, and was inhibited by blockers of megalin receptor. Tissue distribution showed that HCA-Chi-Cu-DOX nanocomplex was specifically accumulated in kidney with a renal relative uptake rate ( r e ) of 25.6. When active anti-fibrosis compound emodin was installed in HCA-Chi-Zn-emodin and intravenously injected to the ureter obstructed mice, obvious attenuation of fibrotic progression was exhibited. It was concluded that HCA-Chi coordination-driven nanocomplex showed special renal targeting capacity and could be utilized to develop drug delivery systems for treating renal fibrosis.
研究领域:
药学
·
纳米技术
·
生物医学工程
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PubMed
高影响因子
Journal of Materials Chemistry A
·
2025
·
IF 9.5
Jianfeng Hu,Huiya Cheng
A challenge in metal protection is developing anti-corrosion materials that possess both high adsorption capacity and intelligent responsiveness. To overcome the limitations of traditional corrosion inhibitors, a novel pH-responsive corrosion inhibitor (PDT@ZIF-90) was developed through a multi-step strategy. Specifically, the catechol-modified polymer–TiO2 hybrid (PDT) was synthesized through Schiff base reactions, which demonstrated dense adsorption on Q235 carbon steel through Fe–N/O coordination. Subsequent ZIF-90-mediated in situ encapsulation enabled precise payload integration of the PDT corrosion inhibitor. UV-vis characterization confirmed that the PDT@ZIF-90 composite system enables pH-triggered intelligent release of the active corrosion inhibitor component under acidic conditions (pH < 6). Electrochemical tests revealed a 95.2% inhibition efficiency for 200 ppm PDT@ZIF-90 in 3.5 wt% NaCl. This dual-functional strategy offers a scalable paradigm for self-adaptive anticorrosion materials suitable for Q235 carbon steel in marine and energy infrastructure applications.
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高影响因子
APPLIED SURFACE SCIENCE
·
2017
·
IF 3.387
Hui Mao,Meihong Liu,Zhenqian Cao,Chunguang Ji,Ying Sun,Daliang Liu,Shuyao Wu,Yu Zhang,Xi-Ming Song
Novel poly(4-vinylphenylboronic acid) (P4VPBA) functionalized polypyrrole/graphene oxide (PPy/GO) nanosheets , which combined the advantages of GO, PPy and PBA groups, were successfully prepared by a simple polymerization of 4-vinylphenylboronic acid (4VPBA) on the surface of pre-treated PPy/GO containing vinyl groups. Because of the synergistic effects of GO with excellent 2D structures and large surface area, PPy with good electronic conductivity and PBA with high recognition capability, P4VPBA/PPy/GO modified glassy carbon electrode presented excellent electrochemical sensing capabilities toward catechol (CC) and hydroquinone (HQ) with good stability, high sensitivity and selectivity, especially giving a large anodic peak potential difference between CC and HQ enough to well distinguish and simultaneously determine the two dihydroxybenzene isomers in their mixture. It is found that PBA groups on the surface of P4VPBA/PPy/GO nanosheets played an essential role for the discrimination and simultaneous electrochemical determination of CC and HQ, which may be due to the selective formation of stable cyclic esters by the covalent interaction between PBA groups and related molecules with a cis -diol in an alkaline aqueous solution. Therefore, P4VPBA/PPy/GO nanosheets can act as a good electrode material for building a steady electrochemical sensor for detecting the two dihydroxybenzene isomers with high sensitivity and selectivity.
研究领域:
材料科学
·
分析化学
·
环境科学
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Jianning Yu,Xiaotao Yang,Peijia Li,Enfeng Yang,Haitao Deng,Guoliang Liu,Xiangdong Yang,Shende Zhai,Lu Zhang,Yining Wu,Dezhao Hao,Caili Dai,Ye Tian,Lei Jiang
Superspreading occurs when the liquid-surface interaction becomes sufficiently strong to overcome the liquid's surface tension, as evidenced by a contact angle approaching 0°. Conventional superspreading relies on complex designed artificial or biological surfaces, or external stimuli, which renders it challenging to exert its efficacy in common scenarios. Herein, inspired by mussel adhesion to rocks, we introduced a strategy utilizing catechol-based compounds that demonstrate strong silicate binding in saline environments, effectively modulating liquid-liquid-solid wettability at the molecular scale. Under mildly basic conditions, catechol induces a stable hydrated layer on the silicate surface, increasing the surface charge and facilitating the dewetting of oil during spreading. The strong interaction between catechol and silicon overcomes the van der Waals forces between silicate and crude oil, enabling efficient oil displacement. Moreover, we demonstrate that polyphenol-treated surfaces perform better in high-salinity environments, where surfactants lose effectiveness due to agglomeration caused by calcium ion. In contrast, polyphenol-based composite agents achieve a 70 % crude oil recovery in oil sand separation and a 90 % recovery in core flooding tests. The study demonstrates the potential of polyphenol‑silicon complexation for cost-effective, scalable superspreading applications in oil recovery and contamination management, highlighting its robust salt tolerance and promising industrial relevance.
研究领域:
材料科学
·
化学工程
·
环境科学
·
石油工程
·
表面化学
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
Pengwen Xie,Feifei Mu,Jérome Chauvin,Serge Cosnier,Xue-Ji Zhang,Dan Shan
Redox-programmable mediators enable context-adaptive signal transduction in electrochemical biosensors. We report a π-conjugated Schiff-base mediator (PT) formed by condensing thionine with 1,10-phenanthroline-2,9-dicarbaldehyde; the phenothiazine donor and phenanthroline acceptor create a rigid, electronically delocalized scaffold. PT switches function with potential and enzymatic context: (i) an oxygen-reduction electrocatalyst at −0.6 V following a two-electron pathway; (ii) a redox relay in a polyphenol oxidase (PPO) sensor at −0.1 V, mediating o -benzoquinone–electrode transfer and achieving a 9.79 nM LOD; and (iii) a conductive matrix for laccase at + 0.23 V that preserves O 2 turnover, affording high selectivity and a wide linear range (1 μM-3 mM; LOD = 821 nM). Mechanistic data confirm that the applied bias and enzyme identity dictate PT’s operative role, evidencing molecular-level adaptability. This π-engineered framework provides a general route to tunable electron mediation and multi-mode catechol sensing across electrocatalytic and enzymatic interfaces.
研究领域:
分析化学
·
生物传感器
·
电化学
·
分子生物学
·
纳米材料
·
环境监测
·
临床诊断
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高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2018
·
IF 3.412
Ting-tiao Pan,Da-Wen Sun,Jitendra Paliwal,Hongbin Pu,Qingyi Wei
Rapid and accurate measurement of polyphenol oxidase (PPO) activity is important in the food industry as PPOs play a vital role in catalyzing enzymatic reactions. The aim of this study was to develop surface-enhanced Raman scattering (SERS) approach for accurate determination of PPO activity in fruit and vegetables using the reduction in SERS intensity of catechol in reaction medium. Within a certain catechol concentration, when a purified PPO solution was analyzed, the reduction in SERS intensity (ΔI) was linear to PPO activity (Ec) in a wide range of 500–50 000 U/L, and a linear regression equation of log ΔI/Δt = 0.6223 log Ec + 0.8072, with a correlation coefficient of 0.9689 and a limit of detection of 224.65 U/L, was obtained. The method was used for detecting PPO activity in apple and potato samples, and the results were compared with those obtained from colorimetric assay, which demonstrated that the proposed method could be successfully used for detecting PPO activity in food samples.
研究领域:
食品科学
·
分析化学
·
酶学
·
农业生物化学
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高影响因子
POLYMERS FOR ADVANCED TECHNOLOGIES
·
2026
·Vol. 37
·期 9
·e70722
·
IF 3.8
Heng Quan,Yatong Tian,Chuanghui Ma,Zengfeng Wei,Lijie Ni,Sakil Mahmud
Inspired by the adhesive chemistry of mussel foot proteins, two catechol-functionalized polyamine chain extenders (NCA1 and NCA2) were synthesized via reductive amination and incorporated into zwitterionic waterborne polyurethane (WPUIP) systems for enhancing the wet rubbing fastness of denim fabrics. Structural characterization confirmed the successful synthesis of the chain extenders and their incorporation into the polyurethane backbone. The resulting emulsions exhibited excellent colloidal stability, maintaining stability over a pH range of 3–9, with particle sizes ranging from 73.37 to 278.36 nm and zeta potentials up to 42.17 mV. The introduction of catechol moieties improved thermal stability and surface hydrophobicity, while the enhanced wet rubbing performance was consistent with stronger catechol-mediated interfacial interactions. Denim fabrics treated with WPUIP displayed significantly enhanced wet rubbing fastness, increasing from < Grade 1 for untreated fabric to Grade 3–4, while maintaining dry rubbing fastness at Grade 4–5. Moreover, a maximum water contact angle of 152.5° was achieved, indicating excellent hydrophobicity. The synergistic integration of catechol-inspired adhesion and zwitterionic stabilization provides an effective strategy for developing high-performance textile fixing agents with broad process adaptability.
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高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2026
·
IF 4.6
Liwen Qu,Hongying Liu,Jia Li,Yinghui Li,Xiangxiang Peng,Lihua Li,Lingao Yi
Ternary composite interface of gold nanoparticles, l -serine and molecularly imprinted polymer modified microelectrode was electrochemically fabricated. • A dual-template molecularly imprinted electrochemical sensor was constructed for the simultaneous detection of HQ and CC. • Molecular imprinting technology can achieve high selectivity for the analyte. • The platform shows potential application in pharmacology, diagnostics and electrophysiology, in-vivo and in-real. • This explore should open an access to integrate with Chinese acupuncture. Catechol (CC) and hydroquinone (HQ), typical toxic phenolic pollutants in industrial effluents, pose risks to ecosystems and human health, demanding rapid, accurate detection. Inspired by traditional Chinese acupuncture, This study developed a molecularly imprinted electrochemical sensor using acupuncture needle (ANE) as substrates. Gold nanoparticles (AuNPs) were electrodeposited on ANE for enhanced conductivity, l -Serine electropolymerized to strengthen recognition, and a melamine-based dual-template molecularly imprinted polymer (MIP) layer constructed as the sensing interface. The sensor was characterized via cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM), and elemental mapping techniques . It showed outstanding selectivity for HQ and CC, with a linear response of 0.1–1000 μM and detection limits of 0.021 μM (HQ) and 0.027 μM (CC), outperforming most reported sensors. In lake water analysis, it exhibited robust anti-interference, stability (RSD < 3.48%), and recoveries of 94.46%–105.6% (HQ) and 98.37%–106.08% (CC). This work integrates traditional Chinese acupuncture wisdom with modern molecular imprinting technology, providing an innovative, cost-effective strategy for on-site environmental monitoring of phenolic pollutants.
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高影响因子
MICROCHIMICA ACTA
·
2011
·Vol. 174
·期 1
·123-130
·
IF 2.578
Li Xinchun,Pan Jianbin,Yang Fan,Feng Jun,Mo Jinyuan,Chen Zuanguang
We report on a simple amperometric detector for use in microchip capillary electrophoresis. A disposable syringe serves as the electrode holder that is fixed at the outlet of the separation channel. A carbon paste electrode is used to detect dopamine (DA) and catechol (CA) after electrophoretic separation. The two model analytes were well separated within 60 s. The response is linear in the concentration range from 4 to 500 μM, and the detection limit is 1.2 μM for DA (S/N = 3:1). The relative standard deviations of the inter-run and inter-electrode peak currents, respectively, are 2.8% and 5.7% for DA, and 3.9% and 6.5% for CA. Favorable column efficiency (expressed by the theoretical plate number which is 5.3 × 104 m -1 for DA) is achieved. The method was successfully applied to the separation and detection of 3-aminophenol (3-AP) in an injection powder containing sodium 4-aminosalicylate. The detection limit of 3-AP is as low as 1.7 μM, which meets the demand of the impurity test. The facile assembly allows convenient replacement of working electrodes and improves the longevity of the microanalytical system.
Voltammetric behaviors of 3-AP and 4-AS at carbon paste electrode (CPE), and microchip electrophoresis-amperometry with CPE for the two analytes.
研究领域:
分析化学
·
电化学
·
微流控
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高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2017
·
IF 3.012
Lu Zhao,Jing Yu,Shuzhen Yue,Lixue Zhang,Zonghua Wang,Pengran Guo,Qingyun Liu
The fabrication of nickel oxide/carbon nanotube (NiO/CNT) nanocomposites by atomic layer deposition (ALD) and their electrochemical performances for sensing hydroquinone (HQ) and catechol (CC) were investigated. NiO nanopaticles with a size of ~ 4.9 nm formed by ALD were highly dispersed on the wall of pristine CNT. Then, the prepared NiO/CNT nanocomposites were used to modify glassy carbon electrode (NiO/CNT/GCE) for electrochemical detection , which presented enhanced electrochemical performances towards detecting HQ and CC. Not only were the redox peak currents of HQ and CC greatly enhanced, but also the oxidization peaks of the both phenolic isomers could be well separated. Under the optimized conditions, the current responses are linear for HQ and CC in the range of 10–500 μM and 10–400 μM, with detection limit of 2.5 μM (S/N = 3) for both compounds.
研究领域:
材料科学
·
分析化学
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高影响因子
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