JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2017
·Vol. 22
·期 4
·973-981
·
IF 2.316
Niu Xiaohui,Mo Zunli,Gao Huhu,Wang Ruijuan,Li Zhenliang,Meng Shujuan,Guo Ruibin
A novel electrochemical chiral sensor was reported for recognizing tryptophan enantiomers based on multi-walled carbon nanotubes functionalized by 3,4,9,10-perylenetetracarboxylic acid binding with the l -lysine (MWCNTs-PTCA-PLL) via electropolymerization. The electrochemical behaviors of the proposed sensors were then characterized by cyclic voltammetry (CV). Differential pulse voltammetries (DPVs) were applied to investigate the stereoselective recognition of tryptophan (Trp) enantiomers. d -Trp and l -Trp showed different responses in DPVs, and a larger selectivity was obtained from d -Trp. pH level and the effect of the incubation time on the chiral recognition were also investigated for optimizing experimental parameters. In addition, the results of analyzing percentage composition revealed this sensor was able to determine the enantiomeric mixtures. The novel strategy with high stability, good sensitivity, and selective characteristics had opened up a new avenue to recognize Trp enantiomers.
✓ 已验证
产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Yidan Liang,Bo Han,Xiaokang Lu,Yuqi Zhang,Ji-Jiang Wang
Lysine (Lys) and arginine (Arg) play a crucial role in the human diets, medical diagnostics, and functional biomaterial synthesis. The imbalance of intake for these two amino acids causes various diseases. Although many analytical techniques have been reported for the detection of amino acids, there are still some issues such as the need for bulky instruments, professional operators, sensitivity to be improved, and real-time detection. Here, a novel colorimetric-fluorimetric probe based on a terphenyl derivative (TPT) has been synthesized for the precise detection of Lys and Arg. In the EtOH-H 2 O solution of TPT, the NH 2 group at the chain end of Lys/Arg undergoes a nucleophilic addition reaction with C N groups of benzothiazole groups of the probe TPT, which breaks the initial long-conjugated system of the probe molecule. As a result, blue shifts can be observed for both UV–vis absorption spectra and fluorescence spectra, accompanying with color changes of the TPT solution. The UV–vis absorption peak of TPT solution shifts from ∼410 nm to ∼325 nm, and the solution color changes from light-yellow to colorless. The fluorescence emission shifts from ∼580 nm to ∼470 nm and the bright-yellow TPT solution changes to blue under the irradiation of 365 nm UV light. For colorimetric method, the limits of detection (LoD) are 0.82 μM and 0.90 μM for Lys and Arg, respectively. For fluorimetric method, they are 2.02 nM and 1.62 nM for Lys and Arg, respectively. In addition, TPT has good selectivity and anti-interference for Lys and Arg. The synthesized probe TPT has been successfully used for the precise detection of Lys and Arg in drugs and for fluorescence imaging of living cells. This work demonstrates that terphenyl-based derivatives are promising organic probes for the detection of Lys and Arg, providing a new way for designing other amino acids probes.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Foods
·
2025
·Vol. 14
·期 14
·2437
·
IF 5.1
Yongtai Wu,Bei Hu,Yuxin Wen,Zuowei Xiao,Lin Li,Xia Zhang,Zhenhui Zhang,Bing Li
Soy sauce (SS) is one of the most popular condiments in the world. However, Nε-carboxymethyl-lysine (CML) and 5-hydroxymethylfurfural (5-HMF), harmful Maillard reaction products, are present in SS. Worse still, their primary sources in SS production remain unclear, and their contents increase during the consumption of heated SS. In this study, CML and 5-HMF were simultaneously monitored, and thermal treatment and the addition of natural product were used to simultaneously reduce their contents during SS production and consumption. During SS production, CML and 5-HMF primarily originated from the raw materials used in SS production, Maillard reactions during fermentation, and the addition of food additives. Also, CML and 5-HMF were simultaneously found in commercial light soy sauce, dark soy sauce, and infant SS, and thermal treatment could increase their contents. Fortunately, additional thermal treatment of semi-finished SS (especially raw sauce and rude light SS) and appropriate concentrations of (−)-epicatechin (100 μM) and ascorbic acid (5 μM), respectively, added to SS for direct and heated consumption, could simultaneously reduce the CML and 5-HMF contents. This study highlights the presence of CML and 5-HMF in SS and proposes practical methods to simultaneously minimize their contents during production and consumption.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TRIBOLOGY INTERNATIONAL
·
2025
·
IF 6.9
Yongfeng Yang,Rui Zhang,Shaowen Dong,Xiaoyang Ma,Xiaotao Li,Jinjin Li
To extend tool life and improve machining quality, this study proposes the use of amino acids as lubricant additives to lubricate the cemented carbide/steel cutting interface. The results showed that Poly-L-lysine (PLL) as an additive in ethylene glycol induced macroscopic liquid superlubricity, achieving a remarkably low coefficient of friction (COF) of 0.006, which further decreased to 0.0007 after 4 h, even under high contact pressures of 796 MPa. The achievement of superlubricity resulted from tribofilm generation, with the combined action of this film and the liquid phase effectively reducing frictional pair contact. The PLL additive induced friction reduction and wear resistance may facilitate breakthroughs in advanced cutting fluid formulations for industrial machining and manufacturing processes.
✓ 已验证
产品关联
DOI
高影响因子
Animal Nutrition
·
2022
·
IF 5.285
Chizhu Ding,Xiang Chen,Xiaoyu Chen,Yue Liu,Menglin Xia,Ziyi He,Qinshu Kang,Xianghua Yan
Lysine is one of the essential amino acids and plays a vital role in the growth, development and health of pigs. Blood lysine concentration is a direct indication of lysine status; however, current methods can not satisfy the demands for rapid and on-site lysine concentration measurement of swine serum. Here, we developed blue-emissive nitrogen-doped carbon dots as a fluorescence probe for the determination of lysine with high fluorescence quantum yield, stability, sensitivity and specificity. The carbon dots were entrapped within hydrogel microstructures to fabricate microfluidic chips for rapid assay for lysine quantification. We further developed an imaging attachment to integrate the microfluidic chip and a smartphone into a portable point-of-care testing platform. This platform requires only 3 μL sample and has a linear detection range of 25 to 300 μmol/L with a limit of detection less than 16 μmol/L, which covers the normal range of lysine concentration in swine serum. We tested lysine concentration in swine serum using this platform with high accuracy, low sample consumption, and within 3 min. Together, these results may provide a rapid and portable platform for dynamic monitoring of swine lysine status and contribute to precise feed formula modulation with low-protein diet strategy.
研究领域:
生物化学
·
分析化学
·
畜牧学
✓ 已验证
DOI
PubMed
高影响因子
ENERGY & FUELS
·
2018
·
IF 3.024
Wei Li,Shujing Wen,Li Shen,Yuchi Zhang,Cheng Sun,Sujing Li
In this work, the aqueous solutions of 1-hydroxyethyl-3-methylimidazolium lysine ([C2OHmim][Lys]) and methyldiethanolamine (MDEA) were developed to obtain an efficient absorbent for CO2 capture. The absorption performance, regeneration performance, reaction mechanism, and kinetic study of the blends were investigated. It was found that, for the blended absorbents, a molar ratio of 8:2 of MDEA/[C2OHmim][Lys] was the optimum ratio based on the absorption rate, absorption capacity, and other factors. The CO2 absorption capacity of the blends is 0.75 mol of CO2/mol of ionic liquid, and the absorption rate was higher than that of the aqueous MDEA solution. The regeneration efficiency of the blends was 93% after the third absorption generation cycle, which was higher than the aqueous solutions of 1 mol/L MDEA (88%) or 1 mol/L [C2OHmim][Lys] (88%) under the same conditions, indicating a better regeneration performance of the blends. The reaction mechanism and kinetic study of the CO2 absorption into the blends were investigated by 13C nuclear magnetic resonance and a double stirred-cell absorber, respectively. [C2OHmim][Lys] in aqueous solution first formed carbamate with CO2, and the next step was hydrolysis of MDEA and partial carbamate, with the production of bicarbonate. It also found that the influence of the temperature in the CO2 absorption was different in the two steps. Also, [C2OHmim][Lys] could promote the hydration reaction of MDEA and CO2 according to the chemical mechanism and kinetic study. The kinetic region was considered to be a fast pseudo-first-order reaction, and the activation energy of the blends was 40.0 kJ mol–1.
研究领域:
化学工程
·
环境科学
✓ 已验证
DOI
高影响因子
BIOMATERIALS
·
2014
·
IF 8.312
Dong Ma,Qian-Ming Lin,Li-Ming Zhang,Yuan-Yuan Liang,Wei Xue
The co-delivery of drug and gene has become the primary strategy in cancer and other disease therapy. To co-deliver hydrophobic drug and functional gene efficiently into tumor cells, a star-shaped copolymer (PP-PLLD-Arg) with a photochemical internalization effect consisting of a porphyrin (PP) core and arginine-functionalized poly( l -lysine) dendron (PLLD-Arg) arms has been designed, and used to co-deliver docetaxel (DOC) and MMP-9 shRNA plasmid for nasopharyngeal cancer therapy. It was found that PP-PLLD-Arg/MMP-9 nanocomplex showed the photo-enhanced gene transfection efficiency in vitro , and could mediate a significant reduce of MMP-9 protein expression in HNE-1 cells. For co-delivery analysis, the obtained PP-PLLD-Arg/DOC/MMP-9 complexes could induce a more significant apoptosis than DOC or MMP-9 used only, and decreased invasive capacity of HNE-1 cells. Moreover, the star-shaped copolymer exhibited better blood compatibility and lower cytotoxicity compared to PEI-25k in the hemolysis and MTT assays , and also showed a good biocompatibility in vivo . Therefore, PP-PLLD-Arg with suited irradiation is a promising non-toxic and photo-inducible effective drug and gene delivery strategy, which should be encouraged in tumor therapy.
研究领域:
药学
·
生物医学工程
·
癌症研究
✓ 已验证
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
·
2020
·
IF 1.431
Yudong Gao
A glassy carbon electrode (GCE) modified with simultaneous electropolymerisation of L-lysine (L-lys) and β-cyclodextrin (β-CD) film (P-β-CD-L-lys/GCE) is proposed as a novel electrochemical platform for the detection of pymetrozine. The electrochemical activity of P-β-CD-L-lys/GCE towards pymetrozine was investigated using cyclic voltammetry experiments in 0.1 M H2SO4. The potential utility of the sensor was demonstrated by applying it to the analytical determination of pymetrozine concentration using linear sweep voltammetry. The linear in the range of 4.0 × 10−8 to 1.0 × 10−6 mol L−1. The detection limit of pymetrozine was found to be 1.3 × 10−8 mol L−1 (S/N = 3). Using this method, we successfully got satisfactory results of pymetrozine in real sample analysis. This work promoted the potential applications of amino acid materials and β-cyclodextrin in environmental analytical chemistry.
研究领域:
环境科学
·
分析化学
✓ 已验证
DOI
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2022
·
IF 6.056
Yungang Cao,Zhaorui Li,Baoling Li,Xin Fan,Miaomiao Liu,Jing Zhao
Protein oxidation, a common quality deterioration in muscle foods, could change the physicochemical characteristics and processability of the meat proteins. The present study focused on the effects of sodium pyrophosphate (PP, 1 mM), Lysine (Lys, 5 mM) and their combination (1 mM PP + 5 mM Lys) on the changes in structure and gelling properties of oxidized myofibrillar protein (Ox-MP). Treatment with the additives modified protein structures, reduced the average particle diameter (d 3,2 and d 4,3 ), restored the gelling behavior of Ox-MP, and remarkably improved the water holding capacity and breaking strength of heat-induced protein gels. The combination of PP and Lys showed a synergistic effect and resulted in the optimal enhancement of Ox-MP gel properties. Specifically, the set gel exhibited a fine, homogeneous and compact microstructure and a breaking strength 4-fold that of Ox-MP. Therefore, a combination of PP and Lys is recommended for aerated meat processing to maintain or enhance the MP gelling potential.
研究领域:
食品科学
·
生物化学
✓ 已验证
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2020
·
IF 3.594
Sizhe Zhang,Yimeng Geng,Nengsheng Ye,Yuhong Xiang
The residue of gentamicin (GEN) in food is a serious threat to human health. Therefore, it is urgent to develop a simple and highly sensitive method for effectively detecting GEN in food. In this study we proposed a lysine-functionalized gold nanoparticles (AuNPs) colorimetric sensor to detect GEN simply and quickly. The detection mechanism as follows: The interaction between lysine and AuNPs causes lysine to adsorb on the surface of AuNPs. After the addition of GEN, the strong hydrogen bond between GEN and lysine promotes the aggregation of AuNPs. The color of AuNPs changed from wine red to blue, which produced obvious color change. UV–vis spectrometer was used to detect it. The results showed that the colorimetric sensor had high selectivity and sensitivity for the detection of GEN, and the linear range and limit of detection were 5–60 nM and 1.22 nM, respectively. In addition, this method has been successfully applied to the quantitative detection of GEN in milk, and the accuracy and recovery were satisfied.
研究领域:
分析化学
·
食品安全
·
纳米技术
✓ 已验证
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2026
·
IF 6.7
Mingtao Hu,Ying Wang,Beibei Zhang,Fei Jin,Hongliang Ge,Jiabing Dai,Feng Gao,Qiong Wu
Achieving a broad effective absorption bandwidth at an ultrathin matching thickness remains a central challenge in the design of microwave absorbing materials. Herein, to the best of our knowledge, an amino-acid-mediated molecular regulation strategy is introduced for the first time into conductive textile/LDH microwave absorber design. L -lysine is employed as a molecular regulator to modulate the nucleation and growth of NiCo-LDH nanoarrays on flexible conductive carbon cloth, leading to the formation of denser and more uniform vertically aligned nanoarrays from the initially loose and disordered deposits. The optimized 1.0Lys sample achieves a minimum reflection loss of −25.0 dB at 17.2 GHz with an ultrathin matching thickness of only 1.00 mm and delivers a broad effective absorption bandwidth of 4.24 GHz at 1.09 mm, demonstrating that strong and broadband absorption are realized under ultrathin matching conditions. The enhanced absorption originates from the synergistic effects of L -lysine-regulated dense nanoarrays, abundant heterogeneous interfaces, molecule-related polar groups, high-frequency dielectric attenuation, and improved impedance matching. In addition, CST-based radar cross section simulations reveal effective high-frequency scattering suppression under different observation angles, highlighting its potential applicability in complex electromagnetic environments. This work provides a previously unexplored amino-acid-mediated molecular regulation route for designing flexible microwave absorbers with broad effective absorption bandwidths at ultrathin matching thicknesses.
✓ 已验证
产品关联
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2026
·
IF 5.8
Min Hu,Yi Liu,Jing Cao,Sha Zhou,Xiaoyu Ma
In this study, lysine (Lys) was used as an electrolyte additive for lead acid batteries (LABs), with pure lead foil replacing the conventional negative grid to regulate electrode-electrolyte interface reactions. The lysine molecule significantly enhanced the solubility of PbSO 4 by binding with Pb 2+ ions and promoted the diffusion of electrolyte into the electrode plate. This finally increased electrode redox activity, reduced plate resistance, and effectively suppressed irreversible sulfation in the battery. The HRPSoC cycle life of the battery extended to 12,588 cycles at a lysine concentration of 0.03 mol·L -1 , representing a 3.9-fold increase compared to the blank battery (without electrolyte additive). The hydrogen evolution current density at -1.6 V potential decreased from 0.0210 A·g -1 to 0.0073 A·g -1 as determined by linear sweep voltammetry (LSV). Through comparing the effects of other amino acids with same amino/carboxyl functional groups but different alkyl chain lengths on battery performance, the relationship between lysine's functional group composition and its enhancement of lead-acid battery performance was investigated, further revealing its mechanism of action. Results indicate that the alkyl chain length of amino acids inversely correlates with the enhancement of lead-acid battery cycle life at identical electrolyte additive concentrations. Shorter alkyl chains significantly suppress irreversible sulfation in batteries, which promotes the conversion between lead sulfate and lead.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）