Scientific Reports
·
2024
·Vol. 14
·期 1
·1-11
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IF 3.8
Cai Xiao-Shi,Jiang Hao,Xiao Jie,Yan Xiangmin,Xie Penggui,Yu Wenjie,Lv Wen-fa,Wang Jun,Meng Xiangyu,Chen Cheng-zhen,Zhang Mingjun,Zhang Yang,Yuan Bao,Zhang Jia-Bao
It is important to study the bacteria that cause endometritis to identify effective therapeutic drugs for dairy cows. In this study, 20% oxytetracycline was used to treat Holstein cows (n = 6) with severe endometritis. Additional 10 Holstein cows (5 for healthy cows, 5 for cows with mild endometritis) were also selected. At the same time, changes in bacterial communities were monitored by high-throughput sequencing. The results show that Escherichia coli, Staphylococcus aureus and other common pathogenic bacteria could be detected by traditional methods in cows both with and without endometritis. However, 16S sequencing results show that changes in the abundance of these bacteria were not significant. Endometritis is often caused by mixed infections in the uterus. Oxytetracycline did not completely remove existing bacteria. However, oxytetracycline could effectively inhibit endometritis and had a significant inhibitory effect on the genera Bacteroides , Trueperella , Peptoniphilus , Parvimonas , Porphyromonas , and Fusobacterium but had no significant inhibitory effect on the bacterial genera Marinospirillum , Erysipelothrix , and Enteractinococcus . During oxytetracycline treatment, the cell motility, endocrine system, exogenous system, glycan biosynthesis and metabolism, lipid metabolism, metabolism of terpenoids, polyketides, cofactors and vitamins, signal transduction, and transport and catabolism pathways were affected.
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JOURNAL OF FLUORESCENCE
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2024
·
IF 2.6
Liu Jiali,Li Chen,Zhang Shen,Wei Xiao,Gao Yue,Wang Fei,Yan Mengwei,Wang Jiaqi,Zhang Yuhui
In recent years, perovskite quantum dots (PQDs) have successfully attracted widespread attention due to their excellent optical properties. However, the instability and toxicity problems of perovskite quantum dots are the main obstacles limiting their applications. In this work, bismuth-based perovskite quantum dots were synthesized by a ligand-assisted reprecipitation method, based on which a novel boric acid-functionalized bismuth-based non-toxic perovskite quantum dots fluorescent sensor (Cs 3 Bi 2 Br 9 -APBA) that can be stabilized in the ethanol phase was prepared by a boron affinity technique. Based on the covalent binding interaction of Cs 3 Bi 2 Br 9 -APBA with oxytetracycline (OTC), a highly selective and sensitive method for the detection of OTC was developed, which effectively solved the problems of poor stability and toxicity in the application of perovskite quantum dots. Under the optimal conditions, the fluorescence intensity of the synthesized Cs 3 Bi 2 Br 9 -APBA was linear with the concentration range of 0.1 ∼ 18 µM OTC, and the detection limit could reach 0.0802 µM. The fluorescence detection mechanism was explored and analyzed by spectral overlap analysis, suppression efficiency study of observed and corrected fluorescence, and fluorescence lifetime decay curve fitting, the mechanism of OTC detection by Cs 3 Bi 2 Br 9 -APBA was identified as the inner filter effect (IFE). In addition, the sensor successfully realized the quantitative detection of trace OTC in the environment, and our study provides a new idea for the preparation of green perovskite materials with high stability and selectivity.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2024
·
IF 5.8
Xiao Wei,Yue Gao,Shen Zhang,Aixia Chen,Jiali Liu,Fei Wang,Ilhem Kerboua,Mengwei Yan,Jiaqi Wang,Yuhui Zhang
In this work, a non-toxic bismuth-based perovskite quantum dot fluorescent nanocomposite (Cs 3 Bi 2 Br 9 @SiO 2 -MIPs) was constructed for the detection of trace oxytetracycline (OTC) in the ethanol phase, which solves the toxicity problem of perovskite quantum dots and realises the application of non-toxic perovskite quantum dots in analysis and detection, the combination boronate affinity effect and molecularly imprinted technology enables highly selective detection of the Cs 3 Bi 2 Br 9 @SiO 2 -MIPs. The basic structure and optical properties of Cs 3 Bi 2 Br 9 @SiO 2 -MIPs were characterized by various characterization methods, and the optimal detection conditions and fluorescence detection ability of Cs 3 Bi 2 Br 9 @SiO 2 -MIPs for OTC were determined. Under the optimal conditions, the Cs 3 Bi 2 Br 9 @SiO 2 -MIPs had a good linear relationship with OTC in the concentration range of 0.8 ∼ 130 μM, and the detection limit was 0.32 μM. Furthermore, the fluorescence detection mechanism of the Cs 3 Bi 2 Br 9 @SiO 2 -MIPs was investigated in detail, which ultimately revealed that the detection mechanism was a synergistic effect of inner filter effect and fluorescence resonance energy transfer. The Cs 3 Bi 2 Br 9 @SiO 2 -MIPs was successfully applied to the detection of trace OTC in real samples. This work provides a new idea for the construction of environmentally friendly and highly selective perovskite quantum dot fluorescent nanocomposite.
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Journal of Water Process Engineering
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2024
·
IF 6.3
Yajie Wen,Jiabin Zhou,Lin He,Dan Liu
In this study, manganese from the cathodes for waste batteries (WBCs) was recovered by hydrometallurgical method as a raw material for the peroxymonosulfate (PMS) activator MnCO 3 , which was successfully synthesized by a simple and environmentally friendly process. MnCO 3 had a good degradation properties for oxytetracycline hydrochloride (OTC-HCl). Under the best conditions through the BoxBehnken Design (BBD), the MnCO 3 /PMS system effectively decomposed 91.3 % of OTC-HCl (initial concentration of 60 mg/L), and the Total Organic Carbon (TOC) removal rate was 63.6 % within just 10 min. Moreover, the system exhibits effectiveness over a wide pH range, with its degradation rate remaining largely unaffected by the presence of inorganic anions. Reactive species, including sulfate radicals (SO 4 ·− ), hydroxyl radicals (･OH), superoxide radicals (O 2 ·− ), and singlet oxygen ( 1 O 2 ), are generated by the degradation system. A series of experiments and characterizations demonstrated that 1 O 2 plays a significant role in the degradation system. This study paves the way for the recycling of spent zinc‐manganese batteries and establishes an efficient multi-mechanism degradation system for treating recalcitrant organic wastewater.
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Journal of Materials Chemistry A
·
2017
·Vol. 5
·期 36
·19378-19389
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IF 8.867
Yingpan Song,Fenghe Duan,Shuai Zhang,Jia-Yue Tian,Zhihong Zhang,Zhuo-Wei Wang,Chun-Sen Liu,Wen-Ming Xu,Miao Du
A series of nanocomposites comprised of iron oxide and mesoporous carbon (denoted as Fe3O4@mC) were derived from an Fe(II)-based metal–organic framework (525-MOF) by calcining at different temperatures. The advantages of chemical functionality, strong bioaffinity, and high stability of the Fe3O4@mC can be combined with the high specific surface area of 525-MOF leading to the formation of Fe3O4@mC nanocomposites as a scaffold for oxytetracycline (OTC) aptamer strands. The use of Fe3O4@mC nanocomposites reveals high OTC detection efficiency. The nanocomposite calcined at 900 °C (denoted as Fe3O4@mC900) is found to be the best candidate toward high-sensitivity and high-selectivity detection of OTC because of its excellent functionality, nanostructural properties, and high electrochemical performance. Accordingly, the Fe3O4@mC900-based electrochemical aptasensor displays high sensitivity with a low detection limit of 0.027 pg mL−1 within a broad linear range of OTC concentration from 0.005 to 1.0 ng mL−1. The aptasensor also exhibits high selectivity, reproducibility, stability, regenerability, and applicability in milk samples. All of these results indicate that the Fe3O4@mC nanocomposites that originated from 525-MOF can be applied in the fields of trace and fast antibiotic determination.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2024
·
IF 9.4
Yingxue Zhang,Mengmeng Wang,Dongyun Chen,Najun Li,Qingfeng Xu,Hua Li,Jianmei Lu
Antibiotics are refractory degradable organic pollutants that present a significant hazard to water environments. In this work, a ternary composite (KB/BMO-GO) comprising of graphene oxide (GO), Bi 2 MoO 6 (BMO), and a cross-linked benzene polymer (KB) was synthesized and applied to promote the synergistic adsorption-photocatalytic degradation of the refractory pollutant, oxytetracycline (OTC). The inclusion of GO and KB in the composite enhanced the OTC adsorption performance of the catalysts, and the construction of Z-scheme heterojunction promoted the photogenerated charge separation efficiency and broadened the range of light absorption, thereby enhancing the photocatalytic performance. Moreover, we compared the performance of catalysts loaded with different mass ratios of KB (x% KB/BMO-GO). Among them, the 15 % KB/BMO-GO catalyst sample had the best OTC degradation performance. Specifically, 15 % KB/BMO-GO could adsorb 69.7 % of OTC in 30 min, reaching an OTC degradation rate of 93.3 % under visible light irradiation. h + and 1 O 2 are the main active substances in the photocatalytic process. In addition, the catalysts are acid-alkali and salt-resistant, as well as good reusability. This study provides a valuable reference for the preparation of highly efficient photocatalysts for synergistic adsorption-photodegradation processes.
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BRAZILIAN JOURNAL OF CHEMICAL ENGINEERING
·
2025
·
IF 1.5
Xiao Yongbo,Gao Yanjiao,Bai Fan,Xiao Jing
Waterborne antibiotics endanger ecological and human health, necessitating efficient treatment. The non-homogeneous catalyst ferrous sulfide (FeS) is readily available and environmentally friendly, capable of effectively activating periodate (PI) to degrade the antibiotic pollutant oxytetracycline (OTC) in water. Therefore, this study systematically investigates the degradation effect of OTC in the FeS/PI system. Through a three-factor (pH, FeS, PI) three-level (–1,0,1) response surface methodology optimization, the optimal reaction conditions were determined as pH 11.07, FeS 1.516 g/L, and PI 1.932 mM, achieving 83.26% OTC degradation efficiency with 39.7% mineralization rate under these conditions. Mechanistic investigations revealed: (1) singlet oxygen ( 1 O 2 ) and superoxide radicals (O 2 •− ) were identified as the primary reactive species (according to radical quenching experiments); (2) LC-MS analysis proposed three potential degradation pathways for OTC; (3) wheat seed germination tests demonstrated the ecological safety of degradation products. The system’s performance could be further enhanced through auxiliary measures: (1) UV irradiation achieved complete degradation; (2) temperature increase (20–50 °C) improved degradation efficiency by 6.76%; (3) ultrasonic treatment provided 0.9% enhancement. Interference resistance tests showed: (1) low concentrations of Cl − (< 10 mM) and HCO 3 − (< 5 mM) promoted the reaction; (2) NO 3 − , SO 4 2− , and humic acid (HA) exhibited negligible effects. Notably, FeS catalyst maintained excellent stability with only 6.6% decrease in OTC conversion rate after five wash-dry-reuse cycles. This technology offers multiple advantages including low energy consumption (ultralow activation energy), high efficiency (potential for complete degradation), and environmental friendliness (no secondary pollution), providing an innovative solution for practical antibiotic wastewater treatment.
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JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 36
·17247-17264
·
IF 4.682
Zhou Dong,Hu Shuyu,Xie Chen,Xu Shiqing,Xu Jing,Li Rong,Hu Pengfei
The room-temperature mechanochemical synthesis method was employed to fabricate the AgCl@Ag-NPs and AgCl@AgNPs/TiO 2 composite photocatalysts efficiently. The polyethylene glycol 400 was introduced to adjust the microstructure and layout of nanoparticles to form a large number of heterojunctions or even heterojunction chains between Ag-NPs and AgCl/TiO 2 . The surface plasmon resonance effect of metallic silver nanoparticle extends the absorption spectrum of composite to the visible region. And the metal–semiconductor heterojunction configuration enables the effective separation of electron–hole pairs to endow them strong catalytic activity for degradation of oxytetracycline under man-made natural light irradiation and, meanwhile, suppresses the bleaching of AgCl to give them good microstructural stability and photocatalytic reusability. In the process of photodegradation of oxytetracycline, AgCl@AgNPs/TiO 2 showed the higher catalytic efficiency through fuller synergy compared to AgCl@AgNPs. This work lays out a green degradation strategy for antibiotics in the ecological environment. Graphical abstract
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CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Wei Ma,Binghua Yao,Wen Zhang,Yangqing He,Yan Yu,Jinfen Niu
A novel piezocatalytic active membrane based on mixed matrix of exfoliated multi-flaw MoS 2 (E-MoS 2 ) nanosheets and polyvinylidene fluoride (PVDF) was synthesized by electrospinning technique. The composition and structure of the obtained E-MoS 2 /PVDF electrospun fiber membranes (EFMs) were characterized via FESEM, HR-TEM, XRD, FTIR and XPS techniques. The piezocatalytic activity of the EFMs was evaluated by the degradation of antibiotic oxytetracycline (OTC) under ultrasonic irradiation in the dark. The 10.0 wt% E-MoS 2 /PVDF EFMs exhibited superior OTC degradation efficiency of 93.08% within 24 min with pseudo-first-order kinetic constant ( k ) of 0.09124 min −1 , which was 21.1 times higher than that of the pure PVDF EFMs. The superior performance was attributed to the synergetic effect of the embedded E-MoS 2 nanosheets and a high proportion of PVDF β -phase (94.1%) to effectively improve the piezoelectric property of composite. In addition, the ultrathin multi-flaw structure of E-MoS 2 provided abundant catalytic active edge sites and increased the surface charge density, promoting the generation of more ∙OH and ∙O 2 – radicals to degrade OTC pollutants. The degradation intermediates of OTC over 10 wt% E-MoS 2 /PVDF EFMs were detected by HPLC–MS and two main degradation pathways were reasonably proposed. The piezocatalytic activity of 10 wt% E-MoS 2 /PVDF EFMs remained stable after five consecutive cycles. This study is meaningful for exploring the composite membrane piezocatalysts for largescale applications in wastewater treatment.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2021
·
IF 8.128
Jin Qin,Shangshi Ye,Kai Yan,Jingdong Zhang
A visible light-driven photoelectrocatalytic system was constructed based on Bi/Bi 2 O 3 /TiO 2 nanotubes (NTs) to treat wastewater containing oxytetracycline and Cu 2+ mixed pollutants. The surface morphology , crystal phase, elemental composition , light absorption property and photoelectrochemical activity of the synthesized Bi/Bi 2 O 3 /TiO 2 NTs were investigated. The composite film , Bi/Bi 2 O 3 /TiO 2 NTs was used for the photoelectrochemical removal of oxytetracycline, and it had excellent visible light photoelectrocatalytic performance. Under optimal conditions, the composite film was simultaneously used to remove coexisting oxytetracycline-Cu 2+ . The study results show that the reduction of Cu 2+ on cathode was promoted by oxytetracycline while the degradation of oxytetracycline on photoanode was slightly suppressed by Cu 2+ . Also, possible photoelectrocatalytic degradation pathways for oxytetracycline-Cu 2+ were analyzed by HPLC-MS.
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TALANTA
·
2025
·
IF 6.1
Mengting Liu,Zuncai Gu,Lu Qian,Kawtar Ettayri,Tao Deng,Chenhao Zhang,Jing Qian,Xingyi Huang,Chengquan Wang
Oxytetracycline (OTC), a broad class of antibacterial medication, has been widely utilized in poultry husbandry and fish farming. However, the presence of OTC residues in the food has become a matter of great concern. These residues have the potential to induce the emergence and spread of bacterial resistance, which can have far-reaching consequences for public health. In this work, we focused on the comparison of the quenching efficiency of UiO-66 and its amino group-modified counterpart UiO-66-NH 2 , towards the fluorescence of nitrogen-doped graphene quantum dots (NGQDs) labeled aptamer (NGQDs-apt). It was found that UiO-66-NH 2 demonstrated a more potent fluorescence quenching ability towards NGQDs-apt, as high as 98.8 %, compared to 69.7 % for UiO-66 without amino functionalization. This enhanced performance is attributed to the improved interaction between the amino groups on UiO-66-NH 2 and the NGQDs-apt, facilitating more effective electron transfer. Consequently, UiO-66-NH 2 was selected as the optimal quencher for the development of a highly sensitive aptasensor. This aptasensor demonstrates a quantitative detection range for OTC spanning from 0.001 to 200 μM with an exceptionally low detection limit of 0.25 nM, showing simplicity, accuracy, stability and great potential for antibiotic residue detection in food samples. This work addresses the urgent need to develop reliable methods for detecting OTC residues in food due to the potential of OTC to trigger bacterial resistance, which is crucial for food safety and public health.
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Journal of Water Process Engineering
·
2025
·
IF 6.7
Qiwen Chen,Zhixiang Tan,Shengxian Cao,Gaili Ke,Liuchun Chen,Yiwen Yang,Tao Han,Shan Yang,Kun Liu,Huichao He
In the treatment of antibiotic-containing wastewater, the influence of temperature on heterogeneous advanced oxidation processes (AOPs) efficiency is often overlooked, hindering practical guidance for cold conditions. Herein, spinel CoFe 2 O 4 nanoparticles were studied as catalysts to activate HCO 3 − /H 2 O 2 (BAP), persulfate (PMS) and peracetic acid (PAA) for oxytetracycline (OTC) degradation at different temperatures, respectively. The apparent activation energy of OTC degradation in CoFe 2 O 4 /PMS, CoFe 2 O 4 /BAP and CoFe 2 O 4 /PAA system was 28.18, 21.02 and 41.17 kJ mol −1 , respectively, showing temperature dependent feature. Three CoFe 2 O 4 -catalyzed AOPs' activity was proportional to temperature. At 5 ± 1.5 °C and 15 ± 1.5 °C, three CoFe 2 O 4 -catalyzed AOPs' efficiency in OTC degradation was unsatisfactory. Under visible light LED irradiation, three CoFe 2 O 4 -catalyzed AOPs' activity for OTC degradation at low temperatures was significantly improved, through making use the photothermal property of spinel CoFe 2 O 4 to rise temperature and accelerate reactions. The degradation of OTC in three CoFe 2 O 4 -catalyzed AOPs was initiated by typical reactive species that be mainly produced from CoFe 2 O 4 activating BAP (•OH, 1 O 2 , O 2 •- , CO 3 •- ), PMS (O 2 •- , •OH, 1 O 2 , SO 4 •- ) or PAA ( 1 O 2 , •OH).
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危险品化学品经营许可证（带存储）