Foods
·
2023
·Vol. 12
·期 5
·951
·
IF 5.2
Xinxin Ding,Xiaoping Li,Qiling Cai,Zhen Ma,Tian Ren,Xinzhong Hu
This study examined the effect of calcium hydroxide (Ca(OH)2, 0.6%,w/w) on structural, physicochemical and in vitro digestibility properties of the complexed system of Tartary buckwheat starch (TBS) and rutin (10%,w/w). The pre-gelatinization and co-gelatinization methods were also compared. SEM results showed that the presence of Ca(OH)2promoted the connection and further strengthened the pore wall of the three-dimensional network structure of the gelatinized and retrograded TBS-rutin complex, indicating the complex possessed a more stable structure with the presence of Ca(OH)2, which were also confirmed by the results of textural analysis and TGA. Additionally, Ca(OH)2reduced relative crystallinity (RC), degree of order (DO) and enthalpy, inhibiting their increase during storage, thereby retarding the regeneration of the TBS-rutin complex. A higher storage modulus (G′) value was observed in the complexes when Ca(OH)2was added. Results of in vitro digestion revealed that Ca(OH)2retarded the hydrolysis of the complex, resulting in an increase in values in slow-digestible starch and resistant starch (RS). Compared with pre-gelatinization, the complex process prepared with the co-gelatinization method presented lower RC, DO, enthalpy, and higher RS. The present work indicates the potential beneficial effect of Ca(OH)2during the preparation of starch-polyphenol complex and would be helpful to reveal the mechanism of Ca(OH)2on improving the quality of rutin riched Tartary buckwheat products.Keywords:Tartary buckwheat;starch-rutin complex;calcium hydroxide;pre-gelatinization;co-gelatinization;physicochemical properties;digestibility
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高影响因子
MICROCHIMICA ACTA
·
2018
·Vol. 185
·期 9
·1-10
·
IF 5.705
Liu Chaoqiao,Huang Jianzhi,Wang Lishi
The authors describe a method for electrochemical synthesis of a nanocomposite consisting of carboxylated multi-walled carbon nanotubes, polythionine and platinum nanoparticles (denoted as cMWCNT@pTh@Pt). The composite was placed on a glassy carbon electrode (GCE) to obtain a sensor for simultaneous determination of myricetin and rutin by differential pulse voltammetry, with typical peak voltages of 0.16 and 0.34 V (vs. SCE). Under optimal conditions, the modified GCE has a linear response in the range of 0.01–15 μM myricetin concentration range, and a 3 nM lower detection limit. For rutin, the data are 0.01–15 μM and 1.7 nM, respectively. The sensor is selective, stable and reproducible. It was successfully applied to the simultaneous determination of myricetin and rutin in spiked juice samples, and satisfactory results were obtained.
A nanocomposite consists of carboxy multi-walled carbon nanotube (cMWCNT), polythionine (pTh) and platinum nanoparticles (Pt) was presented for the simultaneous determination of myricetin and rutin. The nanocomposite shows excellent electrochemical determination performances based on a synergistic effect among cMWCNT, pTh and Pt.
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高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2021
·
IF 5.279
Ningning Zhao,Junpeng Xing,Zhong Zheng,Zifeng Pi,Fengrui Song,Zhiqiang Liu,Shu Liu
The boronate affinity-based oriented and double-shelled surface molecularly imprinted polymers on 96-well microplates (BDMIPs) were designed and applied to high-specific and high-throughput pharmacokinetic (PK) study of rutin and its metabolites from rat plasma without concentration and redissolution. It integrated the advantages of covalent effects-based boronate affinity, noncovalent effects of ethylene imine polymer (PEI) dendrimer, multiple cavities-based double-shelled layers, and multiparallel wells-based 96-well microplates. Furthermore, ultrahigh-performance liquid chromatography triple quadrupole tandem mass spectrometry (UHPLC–MS/MS) was used to accurately quantify targets. It showed lower limits of detection (LODs) up to 100-fold than the conventional method. And PKs of rutin and trace isoquercetin (IQC) were first reported at the same time. The platform can provide a fast, simple, low-cost, high-selective, high-effective, and high-throughput methodological reference for analysis of large-scale samples in the fields of agriculture and food.
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高影响因子
CARBON
·
2018
·
IF 7.082
Huiyu Li,Yuan Xu,Li Zhao,Jie Ding,Mengyang Chen,Guangrui Chen,Yi Li,Lan Ding
The solid-phase pyrolysis method is widely used in the synthesis of fluorescent carbon dots (CDs) because of its large scale and solvent-saving advantages. However, CDs are inclined to agglomerate during the synthesis process, resulting in low quantum yield (QY) and inhomogeneous distribution of particle sizes. Here, a simple and effective solid dispersion surface pyrolysis method was used for the synthesis of tiny-carbon dots (T-CDs) with a high QY. Multi-walled carbon nanotubes (MWCNTs) were used as a support and 2-( N -morpholino)ethanesulfonic acid (MES) as a precursor. MES was uniformly dispersed on the surface of MWCNTs by hydrogen bonding and π-π interactions. Due to the excellent thermal conductivity and rigidity of MWCNTs, the precursor is carbonized without agglomeration. Compared with the CDs obtained by the direct pyrolysis method without the use of a solid support, the particle size of the T-CDs is small (0.69 ± 0.14 nm) and the QY increased from 17.8 to 42.8%. It is anticipated that this method will lead to the improvement of the QY of CDs. Applications of the T-CDs included fluorescence detection of rutin in pharmaceuticals, human urine, and human serum samples, and determination of Al 3+ in tap water samples.
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高影响因子
Surfaces and Interfaces
·
2023
·
IF 6.2
Yulin Xu,Zhiqiang Xu,Congcong Chen,Weihao Ye,Baoyan Guo,Jiemin Qiu,Jianle Zhuang,Chaofan Hu,Bingfu Lei,Guangqi Hu,Yingliang Liu
In this paper, a kind of novel fully UV absorbing carbon dots (R-CDs) were prepared as UV absorbers by a one-step hydrothermal method using natural renewable rutin as raw material. R-CDs can achieve multifunctional applications under acid-base amphoteric conditions. Under acidic conditions, R-CDs have high absorption efficiency (over 98%) in the whole ultraviolet region (200–400 nm) which have wider UV absorption range than commercial water-soluble organic UV absorbers (BP-4) and are almost completely transmitted in the visible light region. The UV absorption mechanism of R-CDs be investigated to the UV absorption systems of degradable cellulose coating (CMC) and the R-CDs@CMC coating was applied to prevent UV leakage of the 395UV chip. Under alkaline conditions, R-CDs remain fully UV absorbing and good absorption stability, but BP-4 loses its function as a UV absorber. Finally, R-CDs was applied to the UV absorption and anti-blue light systems of PU . The R-CDs@PU are more effective than commercially available anti-blue light lenses. At present, the preparation process of R-CDs is simple and rutin is a natural renewable energy source. So, R-CDs have the potential to become a new generation of water-soluble UV absorbers and be applied to prevent blue light.
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高影响因子
ANALYTICAL LETTERS
·
2021
·
IF 2.329
Ping-Rong Zhou,Zhang-Feng Tang,Ke-Su Wei,Ya Wan,Yu-Meng Gao,Yan-Mei Liang,Xiu-Fang Yan,Jun Bin,Chao Kang
Ultraviolet-visible absorption spectrometry is used for the determination of many inorganic, organic, and biological species. However, poor selectivity limits its applications for quantitative analysis in complex mixtures. In this work, its mathematical selectivity was explored using trilinear decomposition on spectral-pH measurements for the selective determination of two flavonoids in three Chinese herbal medicines. Through introducing a pH mode, second-order spectral pH data were constructed per sample. By using trilinear decomposition on the calibration and prediction samples, the rutin signals were extracted from lonicerae japonicae flos, perillae folium, and perillae fructus samples, respectively. Novel second-order calibration was developed for interference-free determination of rutin in these medicines followed by univariate regression of the decomposed intensity versus concentration. The predicted 95% confidence intervals for the concentration of rutin in these samples were 5.19 ± 0.16, 5.81 ± 0.10, and 7.00 ± 0.36 μg mL−1, respectively. These results were validated by high performance liquid chromatography (HPLC). Similarly, interference-free determination of isorhamnetin was achieved in these materials. By increasing the selectivity of ultraviolet-visible spectroscopy with trilinear decomposition, the requirements for sample preparation and chemical separation are reduced. The developed spectral pH second-order calibration allows direct analysis of complex samples by ultraviolet-visible absorption spectrometry due to the mathematical selectivity.
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高影响因子
Toxins
·
2024
·Vol. 16
·期 3
·121
·
IF 3.9
Hira Sayed,Qiongqiong Zhang,Yu Tang,Yanan Wang,Yongpeng Guo,Jianyun Zhang,Cheng Ji,Qiugang Ma,Lihong Zhao
Zearalenone (ZEN) is a non-steroidal estrogenic mycotoxin found in many agricultural products and can cause reproductive disorders, mainly affecting spermatogenesis in male animals. Rutin (RUT) is a natural flavonoid compound recognized for its significant antioxidant, anti-inflammatory and estrogenic properties. The present study aimed to determine the protective role of RUT against ZEN-induced reproductive toxicity in male mice. Twenty-four adult Kunming male mice were divided into four groups: control, RUT (500 mg/kg RUT), ZEN (10 mg/kg ZEN), ZEN + RUT (500 mg/kg RUT + 10 mg/kg ZEN), with six replicates per treatment. The results indicated that RUT mitigated ZEN-induced disruption in spermatogenic cell arrangement, decreased spermatozoa count, and increased sperm mortality in the testes. RUT significantly restored ZEN-induced reduction in T, FSH, LH, and E2 serum levels. Moreover, RUT mitigated ZEN-induced apoptosis by increasing the mRNA expression level ofbcl-2, decreasing the mRNA expression level ofkiss1-r, and decreasing the protein expression level of caspase 8 in reproductive tissues. These findings indicate the protective role of RUT against ZEN-induced reproductive toxicity in male mice by regulating gonadotropin and testosterone secretions to maintain normal spermatogenesis via the HPG axis, which may provide a new application direction for RUT as a therapeutic agent to mitigate ZEN-induced reproductive toxicity.
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高影响因子
Foods
·
2023
·Vol. 12
·期 12
·2302
·
IF 5.2
Yuanfei Li,Huadi Mei,Yanchen Liu,Zhenming Li,Hammad Qamar,Miao Yu,Xianyong Ma
Consumer demand for tasty and quality meat has been quickly increasing. This study investigated how dietary supplemented rutin affects meat quality, muscle fatty acid profile, and antioxidant capacity in the Chinese indigenous Qingyuan partridge chicken. A cohort of 180 healthy 119-day-old chickens was subjected to a randomized assignment into three groups, identified as the control, R200, and R400 groups, with respective supplementation of 0, 200, and 400 mg/kg of rutin. The results revealed insignificance in growth performance, namely, average daily gain, average daily feed intake, and feed-to-gain ratio, across the various treatment groups (p> 0.05). Nevertheless, dietary rutin supplementation increased (p< 0.05) breast muscle yield and intramuscular fat content in breast muscle and decreased (p< 0.05) drip loss in breast muscle. Rutin supplementation increased (p< 0.05) the content of high-density lipoprotein but decreased (p< 0.05) the contents of glucose, triglyceride, and total cholesterol in serum. Rutin supplementation increased (p< 0.05) the levels of DHA (C22:6n-3), total polyunsaturated fatty acids (PUFAs),n-3 PUFAs, decanoic acid (C10:0), the activity of Δ5 + Δ6 (22:6 (n− 3)/18:3 (n− 3)), and the ratio of PUFA/SFA in breast muscle but decreased (p< 0.05) the level of palmitoleic acid (C16:1n-7), the ratio ofn-6/n-3 PUFAs, and the activity of Δ9 (16:1 (n− 7)/16:0). Rutin treatment also reduced (p< 0.05) the contents of malondialdehyde in serum and breast muscle, and increased (p< 0.05) the catalase activity and total antioxidant capacity in serum and breast muscle and the activity of total superoxide dismutase in serum. Additionally, rutin supplementation downregulated the expression ofAMPKαand upregulated the expression ofPPARG,FADS1,FAS,ELOVL7,NRF2,andCATin breast muscle (p< 0.05). Convincingly, the results revealed that rutin supplementation improved meat quality, fatty acid profiles, especiallyn-3 PUFAs, and the antioxidant capacity of Qingyuan partridge chickens.Keywords:rutin supplementation;antioxidant capacity;fatty acid profile;lipid metabolism;meat quality;Chinese yellow-feathered broiler;Qingyuan partridge chickens
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高影响因子
MICROCHIMICA ACTA
·
2011
·Vol. 173
·期 3
·337-345
·
IF 2.578
Yin Huanshun,Zhou Yunlei,Cui Lin,Liu Tao,Ju Peng,Zhu Lusheng,Ai Shiyun
The electrochemical behavior of rutin was investigated in pH 6.0 buffer solution using a glassy carbon electrode coated with graphene nanosheets, chitosan and a poly (amidoamine) dendrimer in pH 6.0 buffer solution. The results indicate that the modified electrode displays electrochemical redox activity towards rutin, and that the oxidation peak current of rutin increases significantly compared to that at other electrodes. The amount of immobilized graphene and dendrimer, pH value, scan rate, accumulation time and accumulation potential were optimized. The kinetic parameters, charge transfer coefficient, transfer electron number, proton transfer number, standard rate constant, were calculated. Under the optimized conditions, the oxidation peak current is proportional to the concentration of rutin in the range between 0.001 and 2.0 μmol L −1 ( R = 0.9991). The detection limit is 0.6 nmol L −1 (at S/N = 3). The electrode exhibits satisfactory selectivity and reproducibility and was applied to the determination of rutin in pharmaceutical preparations, spiked human serum, and traditional Chinese medicine, with recoveries between 97.2 and 104.67%.
1. Preparation of graphene nanosheets and PAMAM modified glassy carbon electrode. 2. Graphene nanosheets and PAMAM improve the electrochemical redox of rutin. 3. The prepared electrode determines rutine with high sensitivity and selectivity. 4. The developed method can determine rutin in pharmaceutical formulations, human serum, and traditional Chinese medicine.
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高影响因子
MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 7
·1-13
·
IF 5.3
Wang Yuefan,Chen Yinzhi,Zhou Yuhe,Wang Yilin,Wu Yingjie,Xie Yixi,Zhao Pengcheng,Hu Xiayi,Fei Junjie
Rutin extracted from natural plants has important medical value, so developing accurate and sensitive quantitative detection methods is one of the most important tasks. In this work, HKUST-1@GN/MoO 3 -Ppy NWs were utilized to develop a high-performance rutin electrochemical sensor in virtue of its high conductivity and electrocatalytic activity. The morphology, crystal structure, and chemical element composition of the fabricated sensor composites were characterized by SEM, TEM, XPS, and XRD. Electrochemical techniques including EIS, CV, and DPV were used to investigate the electrocatalytic properties of the prepared materials. The electrochemical test conditions were optimized to achieve efficient detection of rutin. The 2-electron 2-proton mechanism, consisting of several rapid and sequential phases, is postulated to occur during rutin oxidation. The results show that HKUST-1@GN/MoO 3 -Ppy NWs have the characteristics of large specific surface area, excellent conductivity, and outstanding electrocatalytic ability. There is a significant linear relationship between rutin concentration and the oxidation peak current of DPV. The linear range is 0.50–2000 nM, and the limit of detection is 0.27 nM (S/N = 3). In addition, the prepared electrode has been confirmed to be useful for rutin analysis in orange juice. Graphical Abstract
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高影响因子
危险品化学品经营许可证（带存储）