Nature Communications
·
2024
·Vol. 15
·期 1
·1-11
·
IF 14.7
Huang Jiangfeng,Xue Liang,Huang Yin,Jiang Yanchen,Wu Ping,Fan Xiulin,Zhu Junwu
LiMn 2 O 4 (LMO) is an attractive positive electrode material for aqueous lithium-ion batteries (ALIBs), but its inferior cycle performance limits the practical application. The degradation mechanism of LMO in ALIBs is still unclear, resulting in inability to predictably improve its structural stability. The electrode/electrolyte interface is believed to play an important role in electrode degradation. However, the interactions of the water-containing electrode/electrolyte interface of LMO are underexplored. In this work, we demonstrate the insertion of H 3 O + into LMO during cycling in aqueous electrolyte and elucidate the paradoxical effects of H 3 O + . The crystal H 3 O + enhances the structural stability of LMO by forming a gradient Mn 4+ -rich protective shell, but an excess amount of crystal H 3 O + leads to poor Li + conductivity, resulting in rapid capacity fading. Combining electrochemical analyses, structural characterizations, and first-principles calculations, we reveal the intercalation of H 3 O + into LMO and its associated mechanism on the structural evolution of LMO. Furthermore, we regulate the crystal H 3 O + content in LMO by modifying the hydrogen bond networks of aqueous electrolyte to restrict H 2 O molecule activity. This approach utilizes an appropriate amount of crystal H 3 O + to enhance the structural stability of LMO while maintaining sufficient Li + diffusion.
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JOURNAL OF NANOBIOTECHNOLOGY
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2024
·Vol. 22
·期 1
·1-16
·
IF 10.6
Qi Ji,Zhang Long,Ren Zhongyu,Yuan Yi,Yu Jiahao,Zhang Yining,Gu Linbo,Wang Xu,Wang Yan,Xu Haoyue,Yu Rutong,Zhou Xiuping
Background The Hippo pathway is a conserved tumour suppressor signalling pathway, and its dysregulation is often associated with abnormal cell growth and tumorigenesis. We previously revealed that the transcriptional coactivator Yes-associated protein (YAP), the key effector of the Hippo pathway, is a molecular target for glioblastoma (GBM), the most common malignant brain tumour. Inhibiting YAP with small interfering RNA (siYAP) or the specific inhibitor verteporfin (VP) can diminish GBM growth to a certain degree. Results In this study, to enhance the anti-GBM effect of siYAP and VP, we designed stepwise-targeting and hypoxia-responsive liposomes (AMVY@NPs), which encapsulate hypoxia-responsive polymetronidazole-coated VP and DOTAP adsorbed siYAP, with angiopep-2 (A2) modification on the surface. AMVY@NPs exhibited excellent blood‒brain barrier crossing, GBM targeting, and hypoxia-responsive and efficient siYAP and VP release properties. By inhibiting the expression and function of YAP, AMVY@NPs synergistically inhibited both the growth and stemness of GBM in vitro. Moreover, AMVY@NPs strongly inhibited the growth of orthotopic U87 xenografts and improved the survival of tumour-bearing mice without adverse effects. Conclusion Specific targeting of YAP with stepwise-targeting and hypoxia-responsive liposome AMVY@NPs carrying siYAP and VP efficiently inhibited GBM progression. This study provides a valuable drug delivery platform and creative insights for molecular targeted treatment of GBM in the future.
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Tungsten
·
2025
·
IF 11.2
Shi Xue-Chao,Wang Yi-Mei,Hou Shu-Xian,Yang Guo-Qiang,Liu Xin-Xin,Ge Jun,Gui Lin,Zhang Wei-Wei,Kaoutar Chaldi,Li Shu-Jie,Wang Jun,Ge Fei
Waterborne microbial contamination represents a significant global environmental challenge. Microorganisms can induce water pollution, precipitating infectious disease outbreaks and posing a substantial threat to human health. Currently, the excessive use of conventional antibiotics has resulted in the emergence of bacterial resistance, posing a challenge to the design and development of antimicrobial agents with high antibacterial efficacy in diverse water such as rivers, lakes, and wastewater from microbiology laboratories. Bimetallic nanomaterials, that amalgamate the distinctive characteristics of diverse metals, are garnering attention due to their synergistic properties. In this study, PVP-FeMo 2 S 3 (PVP: Polyvinylpyrrolidone) and PVP-ZnMo 2 S 3 nanocrystals were synthesized by a high-temperature reaction. The prepared nanocrystals exhibited excellent biocompatibility, regular morphology, long-term stability, and remarkable antibacterial effects. The bacterial biofilms could be eradicated by the combination of photothermal (PTT) and photodynamic synergistic effects of PVP-FeMo 2 S 3 and PVP-ZnMo 2 S 3 nanocrystals. PVP-ZnMo 2 S 3 nanocrystals exhibited enhanced PTT conversion efficiency for water treatment. Remarkably, even after 20 cycles of recycling, PVP-ZnMo 2 S 3 retained substantial antibacterial efficacy. The excellent biosafety of PVP-ZnMo 2 S 3 further guarantees the safety of water quality post-treatment. Thus, PVP-ZnMo 2 S 3 bimetallic nanocrystals can serve as a novel antimicrobial agent for the treatment of microbial contamination in water. This study offers a potential strategy to mitigate secondary water pollution and prevent the development of drug resistance among pathogenic microorganisms.
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ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
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2024
·
IF 2.6
Li Fen,Yu Xuemin,Xu Jicai,Di Mohan,Song Hongzan,Run Mingtao
In order to prepare white fluorescent emitting materials, poly(ethylene glycol succinate- co -2,5-furandicarboxylic acid ethylene glycol ester) (PESF) blue fluorescent copolyester was prepared by melt polycondensation, and an orange fluorescent copolyester was prepared by introducing 1,6,7,12-tetrachloro-3,4,9,10-perylene tetracarboxylic acid dianhydride, as one of the fluorescent units, into the molecular chain of poly(butylene glycol isophthalate- co -butylene glycol terephthalate)(PBIT). 4,4-dicyclohexylmethane diisocyanate (HMDI) was used as a chain extender for linking PESF and PBIT to obtain the white fluorescent copolyester. The results showed that introducing 2,5-furandicarboxylic acid (FDCA) into the molecular chain of aliphatic polyesters can significantly enhance the blue fluorescence intensity of the PESF copolyesters, and white-light emission with CIE coordinates of (0.31, 0.35) and (0.30, 0.34) was achieved for the copolyester by varying the content of in the PESF and the copolymerization ratio of PESF and PBIT. In addition, by adjusting the magnitude of the excitation wavelength, it is possible to achieve the fine-tuning of the light color of the white copolyester in a certain region, e.g., the CIE coordinates at 350 nm excitation are (0.32, 0.35). The white copolyester displayed high thermal decomposition temperature about 350 o C, remarkably increased elongation at break above 300%, relatively high tensile strength up to 33.2 MPa; therefore, these performance advantages make enhance their potential for applications.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2024
·
IF 3.8
Zhang Shuang,Jiang Yunhao,Lei Wenli,Zhai Yueming,Liu Juejing,Lyu Xingyi,Li Tao,Guo Xiaofeng,Zhao Yuanmeng,Shan Changsheng,Niu Li
The development of cost-effective and highly efficient electrocatalysts is critical to help electrochemical non-enzymatic sensors achieve high performance. Here, a new class of catalyst, Ru single atoms confined on Cu nanotubes as a single-atom alloy (Ru 1 Cu NTs), with a unique electronic structure and property, was developed to construct a novel electrochemical non-enzymatic glucose sensor for the first time. The Ru 1 Cu NTs with a diameter of about 24.0 nm showed a much lower oxidation potential (0.38 V) and 9.0-fold higher response (66.5 μA) current than Cu nanowires (Cu NWs, oxidation potential 0.47 V and current 7.4 μA) for glucose electrocatalysis. Moreover, as an electrochemical non-enzymatic glucose sensor, Ru 1 Cu NTs not only exhibited twofold higher sensitivity (54.9 μA mM −1 cm −2 ) and wider linear range (0.5–8 mM) than Cu NWs, but also showed a low detection limit (5.0 μM), excellent selectivity, and great stability. According to theoretical calculation results, the outstanding catalytic and sensing performance of Ru 1 Cu NTs could be ascribed to the upshift of the d-band center that helped promote glucose adsorption. This work presents a new avenue for developing highly active catalysts for electrochemical non-enzymatic sensors. Graphical Abstract
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JOURNAL OF SOLUTION CHEMISTRY
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2024
·
IF 1.4
Li Dan,Zhang Xuena,Xin Chunling,Liu Meifang
Densities, dynamic viscosities, and refractive indices for four binary mixtures formed by dibutyl ether with ethyl caprylate, ethyl caprate, ethyl laurate or ethyl myristate over the whole composition range were measured at T =(293.15–323.15 K) and atmospheric pressure. The excess molar volume ( V m E ), viscosity deviation (Δ η ), and refractive index deviation (Δ n D ) for the four systems are calculated and then correlated to the Redlich–Kister polynomial. The V m E and Δ η values are all negative over the entire range of mole fractions. The absolute values of V m E for the mixtures increase with increasing temperature and the absolute values of Δ η decrease with increasing temperature. The Δ n D values with the volume fraction for the four binary systems are all positive over the entire composition range. The experimental results can provide reliable data for the compatibility of biodiesels and their blended fuels.
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NATURE
·
2022
·Vol. 606
·期 7913
·305-312
·
IF 69.504
Liu Tongchao,Liu Jiajie,Li Luxi,Yu Lei,Diao Jiecheng,Zhou Tao,Li Shunning,Dai Alvin,Zhao Wenguang,Xu Shenyang,Ren Yang,Wang Liguang,Wu Tianpin,Qi Rui,Xiao Yinguo,Zheng Jiaxin,Cha Wonsuk,Harder Ross,Robinson Ian,Wen Jianguo,Lu Jun,Pan Feng,Amine Khalil
Li- and Mn-rich (LMR) cathode materials that utilize both cation and anion redox can yield substantial increases in battery energy density 1 , 2 , 3 . However, although voltage decay issues cause continuous energy loss and impede commercialization, the prerequisite driving force for this phenomenon remains a mystery 3 , 4 , 5 , 6 Here, with in situ nanoscale sensitive coherent X-ray diffraction imaging techniques, we reveal that nanostrain and lattice displacement accumulate continuously during operation of the cell. Evidence shows that this effect is the driving force for both structure degradation and oxygen loss, which trigger the well-known rapid voltage decay in LMR cathodes. By carrying out micro- to macro-length characterizations that span atomic structure, the primary particle, multiparticle and electrode levels, we demonstrate that the heterogeneous nature of LMR cathodes inevitably causes pernicious phase displacement/strain, which cannot be eliminated by conventional doping or coating methods. We therefore propose mesostructural design as a strategy to mitigate lattice displacement and inhomogeneous electrochemical/structural evolutions, thereby achieving stable voltage and capacity profiles. These findings highlight the significance of lattice strain/displacement in causing voltage decay and will inspire a wave of efforts to unlock the potential of the broad-scale commercialization of LMR cathode materials.
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Nature Energy
·
2022
·Vol. 7
·期 4
·329-339
·
IF 67.439
Liu Xin,Xie Na,Xue Jiandang,Li Mengyuan,Zheng Chenyang,Zhang Junfeng,Qin Yanzhou,Yin Yan,Dekel Dario R.,Guiver Michael D.
Through-plane (TP) conducting pathways in anion-exchange membranes (AEMs) are desirable for AEM fuel cells as they serve as short and efficient routes for hydroxide ion transport between electrodes, improving power output. Electric and magnetic fields have previously been used to create TP-oriented structures in AEMs, but with modest performance gains. Here we use paramagnetic ferrocenium polymers to prepare TP-oriented AEMs under a magnetic field. The magnetic field induces a mixed-valence state, which effectuates higher anion dissociation and enhanced alkali/redox stability. Our AEMs display a promising TP hydroxide conductivity of ~160 mS cm −1 at 95 °C in water, and no appreciable hydroxide conductivity loss over 4,320 h at 95 °C in alkali. The assembled fuel cells achieve a power output of 737 mW cm −2 at 80 °C and 80% relative humidity, and a durability of 3.9% voltage loss and 2.2% high-frequency resistance increase over 500 h at 500 mA cm −2 , 120 °C and 40% relative humidity.
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Nature Energy
·
2025
·
IF 60.1
Liu Yuan,Mao Huican,Bai Rui,Weng Suting,Zhang Qiangqiang,Rong Xiaohui,Chen Xiao,Zhang Chu,Han Shuai,Ding Feixiang,Wang Xuefeng,Lu Yaxiang,Zhao Junmei,Wei Fei,Chen Liquan,Hu Yong-Sheng
Side reactions between high-voltage cathodes and electrolytes remain a critical obstacle to the advancement of solid-state batteries—particularly for Na-ion systems—due to the higher Na + /Na redox potential. Despite recent extensive efforts, achieving a long cycle life is still challenging at the 4.2 V cut-off (versus Na + /Na). Here we design a room-temperature isotropic epitaxial growth to achieve a relatively uniform and dense metal–organic framework epilayer on Na 3 V 2 O 2 (PO 4 ) 2 F surfaces. Despite using polyethylene oxide, a typical ether-based solid polymer electrolyte, the cathode with isotropic epilayer exhibits enhanced cycling performance at the 4.2 V cut-off (retaining up to 77.9% of its initial capacity after 1,500 cycles). Combining experimental measurements and theoretical analyses, the key factor governing isotropic epitaxial growth behaviour is explicitly elucidated. Furthermore, we develop a self-designed high-sensitivity characterization method, in situ linear sweep voltammetry coupled with gas chromatography–mass spectrometry, to elucidate the failure mechanism of polyethylene oxide on Na 3 V 2 O 2 (PO 4 ) 2 F surfaces and and to reveal the excellent electrochemical stability of the isotropic epilayer. Interestingly, the universality of this approach has also been validated, highlighting its strong potential as an effective strategy for enabling high-energy-density batteries.
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Nature Energy
·
2023
·Vol. 8
·期 10
·1137-1144
·
IF 56.7
Li Huifan,Berbille Andy,Zhao Xin,Wang Ziming,Tang Wei,Wang Zhong Lin
With the global trend towards carbon neutrality, the demand for lithium-ion batteries (LIBs) is continuously increasing. However, current recycling methods for spent LIBs need urgent improvement in terms of eco-friendliness, cost and efficiency. Here we propose a mechano-catalytic method, dubbed contact-electro-catalysis, utilizing radicals generated by contact electrification to promote the metal leaching under the ultrasonic wave. We also use SiO 2 as a recyclable catalyst in the process. For lithium cobalt (III) oxide batteries, the leaching efficiency reached 100% for lithium and 92.19% for cobalt at 90 °C within 6 hours. For ternary lithium batteries, the leaching efficiencies of lithium, nickel, manganese and cobalt reached 94.56%, 96.62%, 96.54% and 98.39% at 70 °C, respectively, within 6 hours. We anticipate that this method can provide a green, high efficiency and economic approach for LIB recycling, meeting the exponentially growing demand for LIB productions.
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Nature Catalysis
·
2025
·
IF 44.6
Xing Chuanwang,Mao Chengliang,Wang Shenghua,Zhou Yuxuan,Wu Lei,Zhang Dake,Kang Dingxuan,Yang Di,Gong Weiting,Wei Wendong,Wang Liang,Li Chaoran,Ozin Geoffrey A.,Yang Deren,Sun Wei
The accumulation of plastic waste has become a global issue. Socially and industrially viable, sustainable technical solutions are therefore required. Here we report a solar thermal catalytic system for polyolefins upcycling using copper nanoparticles encapsulated by stacked two-dimensional silicon. In a chloroaluminate ionic liquid solvent, unlike conventional thermal techniques, the upcycling can proceed under a mild temperature (55 °C) created photothermally under 4 sun irradiation. The polyethylene can be completely transformed into distinct and separable fractions of alkanes (C 3 –C 7 ) and cyclic hydrocarbons (C 8 –C 26 ) within hours, with a total yield of 91%. Mechanistic studies show a pathway involved two β-scissions of C–C bonds and a rapid cyclization. The approach offers versatility in the upcycling of various real-world polyolefin waste and features excellent feasibility in outdoor practices. The analyses of a conceptual upcycling facility using this technology showcase its appeal in both economic and eco-friendliness.
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NATURE
·
2020
·Vol. 579
·期 7799
·368-374
·
IF 42.779
Li Jia,Yang Xiangdong,Liu Yang,Huang Bolong,Wu Ruixia,Zhang Zhengwei,Zhao Bei,Ma Huifang,Dang Weiqi,Wei Zheng,Wang Kai,Lin Zhaoyang,Yan Xingxu,Sun Mingzi,Li Bo,Pan Xiaoqing,Luo Jun,Zhang Guangyu,Liu Yuan,Huang Yu,Duan Xidong,Duan Xiangfeng
Two-dimensional van der Waals heterostructures (vdWHs) have attracted considerable interest 1 , 2 , 3 , 4 . However, most vdWHs reported so far are created by an arduous micromechanical exfoliation and manual restacking process 5 , which—although versatile for proof-of-concept demonstrations 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 and fundamental studies 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 —is clearly not scalable for practical technologies. Here we report a general synthetic strategy for two-dimensional vdWH arrays between metallic transition-metal dichalcogenides (m-TMDs) and semiconducting TMDs (s-TMDs). By selectively patterning nucleation sites on monolayer or bilayer s-TMDs, we precisely control the nucleation and growth of diverse m-TMDs with designable periodic arrangements and tunable lateral dimensions at the predesignated spatial locations, producing a series of vdWH arrays, including VSe 2 /WSe 2 , NiTe 2 /WSe 2 , CoTe 2 /WSe 2 , NbTe 2 /WSe 2 , VS 2 /WSe 2 , VSe 2 /MoS 2 and VSe 2 /WS 2 . Systematic scanning transmission electron microscopy studies reveal nearly ideal vdW interfaces with widely tunable moiré superlattices. With the atomically clean vdW interface, we further show that the m-TMDs function as highly reliable synthetic vdW contacts for the underlying WSe 2 with excellent device performance and yield, delivering a high ON-current density of up to 900 microamperes per micrometre in bilayer WSe 2 transistors. This general synthesis of diverse two-dimensional vdWH arrays provides a versatile material platform for exploring exotic physics and promises a scalable pathway to high-performance devices.
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