PEST MANAGEMENT SCIENCE
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2025
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IF 3.8
Haodong Wang,Yangping Sun,Qi Liu,Mengci Ma,Long Hu,Gehong Wei,Chun Chen
BACKGROUND Soybean production is severely affected by the soil-borne phytopathogenic, Fusarium oxysporum , which causes root rot disease. Artificial nanoplatforms have attracted attention as a sustainable strategy to promote crop growth and protection. RESULTS In this study, mesoporous silica nanoparticles (MSNs) loaded with lipopeptide (Lip), referred to as Lip@MSNs, were synthesized with a diameter of approximately 50 nm and a Lip loading capacity of 22.40 wt%. Lip@MSNs demonstrated potent antifungal activity against F. oxysporum , inducing cell membrane disruption, permeability alterations, nuclear damage, and subsequent cell death. Pot experiment showed that Lip@MSNs significantly reduced the severity of soybean root rot disease by 43.10% while enhancing plant growth and root development. Metabolomic analysis revealed that Lip@MSNs modulated critical metabolic pathways, including zeatin and pyrimidine metabolic pathways in roots. Furthermore, Lip@MSNs recruited beneficial endophytic bacteria, such as antagonistic genera ( Sphingomonas , Variovorax , and Streptomyces ) and growth-promoting genera ( Rhizobium , Ensifer , and Nocardioides ). Correlation analysis highlighted the role of these bacteria in nitrogen fixation and phytohormone production (e.g., trans -zeatin), contributing to reduced root rot disease severity and improved plant health. CONCLUSION These findings demonstrate that the silicon-based delivery system could serve as an effectively tool to control soil-borne phytopathogenic diseases and promote the development of sustainable agriculture. © 2025 Society of Chemical Industry.
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高影响因子
ELECTROCHIMICA ACTA
·
2026
·
IF 5.8
Zhen-Fu Lin,Yu-Qi Ge,Yu-Zhu Zhao,Mei-Na Chen,Hao Li,Nai-Cui Liu,Zhencheng Chen,Guo-Cheng Han,Xiao-Zhen Feng,Heinz-Bernhard Kraatz
Beta-2-Microglobulin (β2M) is a critical biomarker for diseases such as kidney disorders and cancer. However, electrochemical detection methods for β2M remain scarce. Therefore, a novel electrochemical immunosensor for the ultrasensitive detection of β2M was developed in this study. It is based on a ternary composite of polyaniline (PANI), poly- l -cysteine (PL-Cys), and molybdenum disulfide (MoS₂) functionalized onto screen-printed carbon electrodes (SPCE). Through the specific recognition between Beta2-microglobulin antibody (anti-β2M) and its target antigen, and utilizing bovine serum albumin (BSA) to block non-specific binding sites, a BSA/anti-β2M/PANI/PL-Cys/MoS₂/SPCE immunosensor was constructed. Experimental results demonstrate that the sensor exhibits excellent linearity within the 0.001–500 ng/mL (R²=0.9924), with a detection limit as low as 0.33 pg/mL. It shows outstanding selectivity (RSD=2.69%), repeatability (RSD=0.74%), and long-term stability (30-day RSD=2.64%). Recovery rates in serum samples range from 100.40% to 103.76%, confirming its reliability in complex biological matrices. The sensor combines the signal amplification effect of the conductive substrate (PANI/L-Cys/MoS₂) with the impedance effect of the insulating biological layer (antibody-antigen complex), utilizing the quantitative relationship between target analyte concentration and signal attenuation to achieve detection. This approach provides an efficient and low-cost new strategy for on-site rapid screening.
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2026
·
IF 2.8
Guanmei Chen,Yuan Zhang,Yuan Wang,Liangwei Du
In contemporary agriculture, the excessive use of herbicides has raised significant environmental apprehensions. To address these environmental concerns, researchers have turned to the encapsulation of herbicides within nanocarriers as a promising strategy. In this study, alginate/chitosan nanoparticles (ALG/CS NPs) were designed as nanocarriers to encapsulate atrazine (AT). The ALG/CS NPs loaded AT herbicide nanoparticles (AT/ALG/CS NPs) showed an encapsulation efficiency (EE) of the active ingredient above 50% under the rotation speed of 30,000 rpm by high performance liquid chromatography (HPLC). The ALG/CS NPs and AT/ALG/CS NPs were characterized by using dynamic light scattering (DLS), zeta potential, transmission electron microscopy (TEM), and Fourier transform infrared spectroscopy (FTIR), which confirmed the formation of nanoparticles. The assessment of both pre- and post-emergence herbicidal activity against Bidens pilosa L. illustrated a better weed control effect of AT/ALG/CS NPs than AT solutions. Contact angle and liquid holding capacity analyzed confirmed a better adhesive capacity performance of AT/ALG/CS NPs. This study provided a viable and environmentally benign alternative for herbicide delivery, contributing to the advancement of sustainable agricultural practices.
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高影响因子
NEW JOURNAL OF CHEMISTRY
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2026
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IF 2.5
Jingjie Hu,Guofu Zeng,Xiaoyan Long,Xiaoyan Lin
Amidated collagen (A-COL) with good biocompatibility was synthesized via carbodiimide-mediated coupling of L-arginine to native collagen (COL). The structure and charge type of A-COL and COL were characterized by FTIR, zeta potential analysis and elemental analysis (EA). A-COL was incorporated into the foam detergent as both an antibacterial agent and foam stabilizer. The antibacterial activities of A-COL against E. coli and S. aureus were analyzed, along with its impact on, and mechanism for enhancing, the detergent's foaming capacity and foam stability. The results showed that A-COL inhibited both bacteria, with MIC values of 0.312 mg mL−1 and 0.078 mg mL−1, respectively. The antimicrobial mechanism of A-COL involves its positively charged and synergistically active structure, which enhances electrostatic interactions and destroys the cell's integrity. Foam stability with A-COL was 1.43-fold higher than without A-COL. The addition of A-COL enhances the foam stability of the foam detergent through its long-chain molecules forming an interweaving network structure. The detergent containing A-COL exhibited no skin irritation, excellent biocompatibility, and a predicted shelf life of over 3 years as determined by accelerated thermal stability testing. The dual-functional A-COL significantly enhances the detergent's antibacterial efficacy, storage stability, foam-stabilizing capacity, and biocompatibility, demonstrating considerable potential for application in biomass-based detergents.
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高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2026
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IF 4.3
Yuanyuan Ma,Sunan Tian,Quanlin Ma,Jinrong Liu,Guoyue Bi,Yifang Yan,Xiaoxin Yang,Ziqiang Lei
In arid and semi-arid regions, farmland salinization poses a significant challenge to agricultural productivity and economic development. This study developed a highly water-absorbing gel material (PN-MA-L-Glu/PAA) through the synthesis of N-maleoyl-L-glutamic acid (N-MA-L-Glu) and its subsequent copolymerization with acrylic acid. The material exhibited remarkable water absorption capacities of 2880 g/g in deionized water, 272 g/g in tap water, and 175 g/g in a 0.9 % NaCl solution. Experimental results demonstrated that incorporating 0.15 % of the material significantly enhanced soil nutrient retention by 52.1 % and improved moisture retention by 73.74 %. Salt exclusion tests revealed that the material effectively reduced the concentrations of both cations and anions, with its anion adsorption performance aligning well with theoretical predictions. In pot experiments, the addition of 0.15 % and 0.2 % of the material resulted in germination rates of 86.2 % and 100 %, respectively. Notably, 0.2 % of the material reduced the total salt content in the soil surface layer by 59.1 %, decreased the pH by 0.67, and lowered the electrical conductivity (EC) by 3928.4 μS/cm. This innovative material effectively mitigates the migration of soil moisture and salts while stabilizing salt ions through chelation and adsorption mechanisms. Furthermore, its biodegradable properties make it an ideal solution for addressing soil salinization in arid and semi-arid regions, offering a promising approach for soil remediation and sustainable agricultural management.
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高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2026
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IF 5.4
Feng Gao,Jinghuan Fu,Siyuan Song,Yuhang Yao,Zeyu Guo,Xingyu Wang,Fei Jin,Ying Wang,Gongxun Bai
Surface and interfacial regulation is critical for breathable wearable materials that require stable humidity-responsive electrical output together with auxiliary thermal functionality. Herein, we report a lysine-stabilized MXene/polyvinyl alcohol (PVA) electrospun nanofibrous membrane in which Ti₃C₂Tₓ MXene is incorporated into a porous and vapor-permeable fiber network. This design promotes interfacial compatibility between MXene and PVA, improves its dispersion within the polymer matrix, and preserves a breathable porous architecture that favors water-vapor transport and interfacial moisture uptake. The 2 mg/mL MXene-Lys/PVA exhibits a strong humidity-dependent electrical response, delivering a resistance response of 10,665 over 40–90% RH, and stable operation during repeated cycling and two months of storage. The sensing behavior is mainly associated with water-adsorption-mediated modulation of charge transport within the hydrated polymer/MXene interfacial network, while an additional low-frequency interfacial process emerges under high-humidity conditions. Beyond humidity sensing, the composite largely retains the vapor-transport capability of the porous PVA matrix and simultaneously provides effective photothermal conversion under light irradiation. A garment-mounted PET-ITO prototype further enables real-time wireless transmission of activity-associated humidity-responsive signals. These results show that L -lysine-assisted MXene integration in electrospun porous membranes provides a composition-tunable platform for humidity-responsive electrical readout and photothermal heating demonstrations. Download: Download high-res image (187KB) Download: Download full-size image
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2026
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IF 9.1
Bin Wen,Fan Chen,Yi Ran,Dongyun Que,Zhihao Zhang,Youwei Zeng,Yuyuan Yao
Molybdenum disulfide (MoS₂) is a promising inorganic co-catalyst for Fenton processes due to its structural durability and avoidance of secondary organic pollution. However, the conventional 2H-phase MoS₂ suffers from intrinsically low conductivity, severely limiting Fe 3+ reduction in the Fenton reaction. Herein, L-cysteine served as a multifunctional precursor during the preparation of MoS₂, promoting a slow-release sulfur supply, carbon‑nitrogen co-doping, and the prevention of restacking. The carbon and nitrogen co-doped molybdenum disulfide (CN-MoS 2 ) architecture was fabricated via a single-step hydrothermal reaction mediated by sodium molybdate, thiourea, and L-cysteine. Remarkably, benefiting from the introduction of L-cysteine, the resulting CN-MoS 2 exhibited a high 1 T-phase content (68%), abundant sulfur vacancies, and a substantially reduced particle size. CN-MoS 2 accomplished near-complete elimination of carbamazepine (CBZ) within merely 3 min, yielding a prominent apparent rate constant of 0.7111 min −1 , which is a 19-fold kinetic acceleration over thiourea-derived MoS 2 . CN-MoS₂ also exhibited high TOC removal, broad-spectrum degradation, and robust CBZ removal under various water conditions. Additionally, electrochemical analyses further verified that CN-MoS₂ reduced charge-transfer resistance and enriched electron density, thereby facilitating rapid electron shuttling to Fe 3+ . Concurrently, quenching experiments and electron paramagnetic resonance (EPR) diagnostics unambiguously validated SO 4 •- , 1 O 2 and O 2 •- as the driving reactive forces. Moreover, a continuous-flow device incorporating a CN-MoS 2 -based membrane exhibited outstanding performance in wastewater purification. This work offers a new strategy for designing high-activity co-catalysts for advanced oxidation processes.
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高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2026
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IF 6.7
Bo Zhang,Liqun Shen,Cheng Yu,Zhibo Leng,Zhihong Zhu,Lingfei Hua,Zijie Li
d-Allose, one of important rare sugars, has attracted increasing attention due to its low caloric value and remarkable physiological activities. l-Rhamnose isomerase (L-RI) catalyzes the reversible conversion of d-allulose to d-allose. However, its industrial application is limited by inadequate catalytic efficiency. In this study, L-RI from Clostridium thermosuccinogenes was identified and systematically characterized. Using a semirational protein engineering strategy, loop residues adjacent to the catalytic core and potential active sites predicted by the HotSpot Wizard web server were targeted. The resultant triple mutant N137Q/D258R/A265I achieved a d-allose conversion rate of 21.8% and a productivity of 130.8 g·L–1·h–1 within 1 h using 600 g·L–1 d-allulose. Molecular dynamics (MD) simulations revealed that modulation of loop flexibility enhanced the enzyme turnover rate. By fine-tuning loop flexibility while maintaining the structural integrity of the enzyme, this engineered mutant reduces the risk of enzyme inactivation during prolonged high-temperature catalysis. Collectively, these results highlight its potential for industrial d-allose production and provide valuable insights for the modification of L-RIs and related enzymes.
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高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2026
·
IF 8.7
Dongdong Guo,Wenlida Mu,Chang Liu,He Qian
Three colloidal systems (LP-CP, SC-CP, CYC-CP) were systematically compared for encapsulating curcumin- Brassica rapa L. polysaccharide mixture (CP). • SC-CP exhibited the highest curcumin loading capacity, superior curcumin thermal stability, and peak colonic accumulation of curcumin in vivo . • SC-CP significantly promoted the production of acetate, propionate, and butyrate during in vitro colonic fermentation, outperforming LP-CP and CYC-CP. • In a mouse model, SC-CP enriched beneficial genera, including Lachnospiraceae_NK4A136_group and Akkermansia and increased cecal butyrate levels. • The choice of colloidal carrier fundamentally governs the colonic delivery efficiency and gut microbiota remodeling capacity of the curcumin-polysaccharide mixture. The therapeutic potential of curcumin is severely constrained by its poor physicochemical stability and low oral bioavailability. Co-formulation with Brassica rapa L. polysaccharide offers a promising strategy to enhance its functionality; however, the impact of different colloidal delivery systems on the encapsulation performance and subsequent biological fate of this mixture remains unclear. In this study, we systematically compared three spray-dried delivery platforms, including liposomes (LP-CP), sodium caseinate nanoparticles (SC-CP), and β-cyclodextrin inclusion complexes (CYC-CP), for encapsulating CP. Our results demonstrated that the carrier system critically determined encapsulation performance, with SC-CP exhibiting superior curcumin loading capacity (7.24%), curcumin thermal stability (82.87% retention at 95 °C), and favorable hygroscopicity profiles. Notably, SC-CP facilitated enhanced colonic accumulation in vivo , achieving a peak accumulation of 53.45% at 8 h post-gavage, representing a 15-fold increase compared to curcumin from unencapsulated CP. By integrating in vitro fermentation models with in vivo animal experiments and employing 16S rRNA sequencing alongside short-chain fatty acid (SCFA) analysis, we systematically elucidated the carrier-specific modulatory effects on the gut microbiota. In the in vitro fermentation system, SC-CP significantly promoted the production of acetate, propionate, and butyrate, while enriching butyrate-producing genera such as Lachnospiraceae_NK4A136_group . In the in vivo animal model, SC-CP intervention resulted in a 1.6-fold increase in cecal butyrate levels and a marked increase in the abundance of beneficial genera, including Akkermansia , demonstrating superior modulation of microbial community structure and metabolic function. Collectively, these findings establish that the selection of a colloidal carrier not only dictates the physicochemical stability of the curcumin-polysaccharide mixture but also governs its spatiotemporal distribution within the gastrointestinal tract and its prebiotic capacity to remodel the gut microecology. This study provides a theoretical foundation for the rational selection of delivery systems to maximize the functional efficacy of bioactive ingredients in functional food applications. Download: Download high-res image (195KB) Download: Download full-size image
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PubMed
高影响因子
Biomaterials Advances
·
2026
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IF 6.7
Jieyu Su,Yuxin Zhang,Yongqiang Cao,Tiantian Ren,Kunxi Zhang,Dong Chen,Jingbo Yin
PBLG HNMs feature open-hollow nanofibrous architecture and injectability. • PBLG self-assembly drives the internal ECM-like nanofibrous network. • Covalent GHK-Cu grafting affords stable osteogenic-angiogenic activity. • PBLG-GCu HNMs promote BMSC osteogenesis and HUVEC angiogenesis. Biomimetic fibrous microspheres with a high specific surface area hold substantial promise for bone tissue engineering. In this study, asymmetric open-hollow nanofibrous microspheres (HNMs) were fabricated from polypeptide poly( γ -benzyl- L -glutamate) (PBLG) via a combination of emulsion and thermally induced phase separation, yielding PBLG HNMs. To further impart biofunctionality, the copper peptide (GHK-Cu) was covalently grafted onto the microspheres to obtain osteoinductive and pro-angiogenic PBLG-GCu HNMs. The optimized microspheres exhibited an average diameter of 372 ± 102 μm, which is suitable for injectability, and an opening size of 219 ± 53 μm, enabling efficient cellular infiltration. The internal surface featured an interconnected nanofibrous network with a fiber diameter of 417 ± 78 nm, mimicking the extracellular matrix (ECM) microenvironment and providing abundant cell-interactive sites. Live/Dead staining and CCK-8 assays confirmed the cytocompatibility of the PBLG-GCu HNMs. Compared with non-functionalized PBLG HNMs, PBLG-GCu HNMs enhanced bone marrow mesenchymal stem cell (BMSC) mineralization and upregulated osteogenic gene expression, with Runx2, OPN, and OCN expression increased by 1.61-, 3.53-, and 2.29-fold, respectively. In addition, the tube formation assay verified robust angiogenic stimulation. Overall, the PBLG-GCu HNMs integrated hierarchical structural biomimicry with dual osteogenic-angiogenic bioactivity, exhibiting great potential as injectable scaffolds for repairing irregular bone defects.
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高影响因子
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
·
2018
·Vol. 54
·期 3
·715-722
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IF 2.383
Aalim Halah,Belwal Tarun,Wang Youyong,Luo Zisheng,Hu Juwu
This study was designed to establish an efficient purification method for phenolic compounds from rice bran and to acquire insightful knowledge of purification impact on its chemical constituents, antioxidant and antidiabetic activity. Among the eight macroporous resins investigated, HPD-300 resin was verified to bosses superior adsorption and desorption qualities for the extract. Purification parameters were optimised. Eighteen phenolic compounds were identified using HPLC-PDA, the contents of ferulic acid and syringaldehyde were significantly (P < 0.05) higher than the other constituents. However, phenolic compounds concentrations varied significantly (P < 0.05) after HPD-300 resin purification. In addition, the extract exhibited a significant (P < 0.05) increase in total flavonoid contents, in vitro antioxidant (DPPH and FRAP) and antidiabetic (α-glucosidase and BSA-glycation inhibition) activity after HPD-300 resin treatment. These findings indicate that selection of resin and applying optimal purification condition is an appropriate economical approach for obtaining bioactive phenolic compounds from rice bran.
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高影响因子
Food Bioscience
·
2026
·
IF 6.2
Hui Zhang,Mengjia Xu,Felix Wambua Muema,Jun Ding,Mingquan Guo
Chrysanthemum indicum L. has traditionally been utilized as one of the main ingredients in many functional foods or tea for lipid-lowing by advantages of abundant bioactive components and lower side effects. However, the specific compounds responsible for these beneficial lipid-lowering properties remain unrevealed. In this study, lipase-immobilized hollow fibers were first developed to screen out potential lipase ligands by integrating ultra-performance liquid chromatography-quadrupole-time of flight mass spectrometry (UPLC-QTOF-MS/MS) with a molecular networking approach, in which the incorporation of glutaraldehyde as crosslinker achieved a 2.24-fold increase in enzyme loading capacity. The immobilized lipase retained over 50% relative viability after 6 enzymatic cycles or 10 h of storage (4 °C). A total of 30 potential ligands were successfully screened out and identified. Among them, the inhibitory activities and the mechanism of action of three representative candidate ligands (Ethyl chlorogenate, Luteolin 7- O -glucuronide and Ethyl caffeate) were further investigated through in vitro enzyme activity assays and molecular docking analysis. Overall, the current study proposed a promising strategy for the rapid discovery and identification of bioactive compounds against obesity from complex natural extracts in natural foods.
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危险品化学品经营许可证（带存储）