ACS Applied Materials & Interfaces
·
2018
·
IF 8.097
Huangxu Li,Zhian Zhang,Ming Xu,Weizhai Bao,Yanqing Lai,Kai Zhang,Jie Li
The application of sodium-ion batteries (SIBs) requires a suitable cathode material with low cost, nontoxic, high safety, and high energy density, which is still a big challenge; thus, a basic research on exploring new types of materials is imperative. In this work, a manganic pyrophosphate and carbon compound Na3.12Mn2.44(P2O7)2/C has been synthesized through a feasible sol–gel method. Rietveld refinement reveals that Na3.12Mn2.44(P2O7)2 adopts a triclinic structure (P1̅ space group), which possesses spacious ion diffusion channels for facile sodium migration. The off-stoichiometric phase is able to offer more reversible Na+, delivering an enhanced reversible capacity of 114 mA h g–1 at 0.1 C, and because of the strong “inductive effect” that (P2O7)4– groups imposing on the Mn3+/Mn2+ redox couple, Na3.12Mn2.44(P2O7)2/C presents high platforms above 3.6 V, contributing a remarkable energy density of 376 W h kg–1, which is among the highest Fe-/Mn-based polyanion-type cathode materials. Furthermore, the off-stoichiometric compound also presents satisfactory rate capability and long-cycle stability, with a capacity retention of 75% after 500 cycles at 5 C. Ex situ X-ray diffraction demonstrates a single-phase reaction mechanism, and the density functional theory calculations display two one-dimensional sodium migration paths with low energy barriers in Na3.12Mn2.44(P2O7)2, which is vital for the facile sodium storage. We believe that this compound will be a competitive cathode material for large-scale SIBs.
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高影响因子
Science Advances
·
2019
·Vol. 5
·期 1
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IF 12.804
Yabin Zhang,Lin Zhang,Lidong Yang,Chi Ian Vong,Kai Fung Chan,William K. K. Wu,Thomas N. Y. Kwong,Norman W. S. Lo,Margaret Ip,Sunny H. Wong,Joseph J. Y. Sung,Philip W. Y. Chiu,Li Zhang
A rapid, direct, and low-cost method for detecting bacterial toxins associated with common gastrointestinal diseases remains a great challenge despite numerous studies and clinical assays. Motion-based detection through tracking the emerging micro- and nanorobots has shown great potential in chemo- and biosensing due to accelerated “chemistry on the move”. Here, we described the use of fluorescent magnetic spore–based microrobots (FMSMs) as a highly efficient mobile sensing platform for the detection of toxins secreted by Clostridium difficile ( C. diff ) that were present in patients’ stool. These microrobots were synthesized rapidly and inexpensively by the direct deposition of magnetic nanoparticles and the subsequent encapsulation of sensing probes on the porous natural spores. Because of the cooperation effect of natural spore, magnetic Fe 3 O 4 nanoparticles, and functionalized carbon nanodots, selective fluorescence detection of the prepared FMSMs is demonstrated in C. diff bacterial supernatant and even in actual clinical stool samples from infectious patients within tens of minutes, suggesting rapid response and good selectivity and sensitivity of FMSMs toward C. diff toxins.
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高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2018
·Vol. 28
·期 36
·1802684
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IF 13.325
Zhongyu Zhang,Malin Li,Yu Gao,Zhixuan Wei,Meina Zhang,Chunzhong Wang,Yi Zeng,Bo Zou,Gang Chen,Fei Du
Hybrid potassium-ion capacitors (KICs) show great promise for large-scale storage on the power grid because of cost advantages, the weaker Lewis acidity of K + and low redox potential of K + /K. However, a huge challenge remains for designing high-performance K + storage materials since K + ions are heavier and larger than Li + and Na + . Herein, the synthesis of hierarchical Ca 0.5 Ti 2 (PO 4 ) 3 @C microspheres by use of the electrospraying method is reported. Benefiting from the rich vacancies in the crystal structure and rational nanostructural design, the hybrid Ca 0.5 Ti 2 (PO 4 ) 3 @C electrode delivers a high reversible capacity (239 mA h g −1 ) and superior rate performance (63 mA h g −1 at 5 A g −1 ). Moreover, the KIC employing a Ca 0.5 Ti 2 (PO 4 ) 3 @C anode and activated carbon cathode, affords a high energy/power density (80 W h kg −1 and 5144 W kg −1 ) in a potential window of 1.0–4.0 V, as well as a long lifespan of over 4000 cycles. In addition, in situ X-ray diffraction is used to unravel the structural transition in Ca 0.5 Ti 2 (PO 4 ) 3 , suggesting a two-phase transition above 0.5 V during the initial discharge and solid solution processes during the subsequent K + insertion/extraction. The present study demonstrates a low-cost potassium-based energy storage device with high energy/power densities and a long lifespan.
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高影响因子
Nature Communications
·
2025
·Vol. 16
·期 1
·1-13
·
IF 15.7
He Yingchun,Ma Dong-Dong,Ma Ke,Li Xiaofang,Han Lili,Wu Xin-Tao,Zhu Qi-Long
Electrochemically constructing C–N and N–C–N bonds provides an economical and sustainable alternative to conventional chemosynthesis. Herein, a hierarchically ordered open superstructure of N-doped carbon isolated with accessible three-coordinated Zn single-atom sites is explored for efficient electrocatalytic N–C–N coupling. Benefiting from the distinctive structural merits, this catalyst enables electrocatalytic preparation of N–C–N bonded compounds from methanol and amines. Notably, the Faradaic efficiency and selectivity of N,N,N’,N’ -tetramethyldiaminomethane reach up to 77% and 96% at 0.8 V, respectively. Further integrating the aminoalkylation reaction, an electro-thermo cascade synthesis is explored with the electrochemically obtained N,N,N’,N’ -tetramethyldiaminomethane serving as a unique reagent, leading to a specific set of organonitrogen compounds with (dimethylamino)methyl substituent, including topotecan hydrochloride, an anti-tumor drug, with a high yield of 95%. Furthermore, the in situ spectroscopic characterization and calculations unveil that the under-coordinated Zn-N 3 sites play a pivotal role in stabilizing the key *CH 2 O intermediate, thereby facilitating subsequent nucleophilic addition with amines.
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PubMed
高影响因子
Journal of Advanced Research
·
2025
·
IF 13
Yajing Li,Runping Liu,Jianan Li,Feng Gao,Zhi Ma,Kaihong Xie,Fanghong Li,Bing Xu,Qi Zheng,Yajie Cai,Jiaorong Qu,Xiaoyong Xue,Kexin Jia,Xiaojiaoyang Li
Introduction Cholestatic liver diseases are highly prevalent and lack effective treatment, ultimately progressing to end-stage liver diseases. Our recent study indicates that the interplay between c-MYC and lncRNA H19 exacerbates the ductular reaction during cholestasis. Objective: This study aims to unveil the underlying mechanisms of the protective effects of senkyunolide A (SenA) on cholangiocyte overproliferation in cholestatic liver diseases. Methods : Through comprehensive characterization using RNA sequencing, CHIP analysis, protein truncation, amino acid mutation or deletion, and the development of SenA derivatives, we explored the effects and mechanisms of SenA in vivo in bile duct ligation mice and in vitro in primary cholangiocytes. Results : We demonstrated that SenA effectively mitigates cholangiocyte hyperproliferation by epigenetically suppressing c-MYC expression and disrupting the downstream H19, Let-7a and Lin28a. Mechanically, we identified a potential interaction between the carbonyl group in SenA and Arg483 in TRAF6, disrupting the TRAF6-HDAC3 complex. This dissociation facilitates the binding of HDAC3 to the MYC promoter region, resulting in enhanced histone deacetylation and transcriptional suppression. Conclusion : We highlight the therapeutic potential of SenA in cholestatic liver diseases by elucidating its role in epigenetic regulation.
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PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Xinmei Qian,Chunxiang Li,Mingyu Zheng,Jinglun Wang,Haowen Huang,Keqin Deng
In this work, a regenerable magnetic omeprazole electrochemical sensor was developed for the first time. Firstly, a magnetic bamboo-like nitrogen-carbon (N-C) nanotubes encapsulated with iron-nickel alloy (FeNi) nanoparticles (FeNi@N-CNTs) was prepared by a pyrolysis route. The characterization techniques including high resolution transmission electron microscopy (HRTEM), scanning electron microscope (SEM), X-ray diffraction (XRD), energy disperse spectroscopy (EDS), and X-ray photoelectron spectroscopy (XPS) revealed the surface morphology, structure, and chemical composition of the FeNi@N-CNTs. Cyclic voltammograms (CVs) and electrochemical impedance spectroscopy (EIS) results indicated that FeNi@N-CNTs had excellent conductivity and greatly facilitated the electron transfer. By applying FeNi@N-CNTs, a designed magnetic base support, and screen-printed electrode (SPE), a regenerable magnetic SPE was developed. The presence of FeNi@N-CNTs caused better omeprazole electron transfer kinetics at SPE surface. The FeNi@N-CNTs/SPE showed a linear detection range of 0.05–25.0 μM with a detection limit of 14 nM (S/N = 3) for detecting omeprazole. Due to the FeNi@N-CNTs adhering to SPE surface by magnetic control and easy disengagement from the electrode surface by magnetism, the proposed sensor was simple, regenerable, and cost-effective.
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高影响因子
Reaction Chemistry & Engineering
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2025
·
IF 3.1
Weidong Liu,Jianguo Liu
Reusable catalysts based on non-noble metals with broad applicability for nitrile catalytic hydrogenation are key to achieving more sustainable primary amine production. Herein, a simple and efficient carbon-coated non-noble nickel-based catalyst (Ni/NiO@C-600-200-1-H₂O) was developed for the hydrogenation of aromatic substituted nitriles to aromatic substituted amines under relatively mild conditions (120 °C, 10 bar H₂, 4 h). The carbon-coated structure endows the catalyst with excellent anti-agglomeration properties, significantly enhancing its cyclic stability. The catalyst exhibits high tolerance toward various functional groups, including halogen, methyl, and methoxy, achieving remarkable conversion rates (over 99%) and product selectivity (up to 98.25%). Additionally, the catalyst's magnetic properties facilitate easy recovery and reuse. When applied to a continuous flow reactor for benzonitrile hydrogenation under optimized conditions, the catalyst demonstrated a conversion rate and selectivity exceeding 99%, with continuous operation lasting up to 31 h.
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高影响因子
AQUACULTURE
·
2024
·
IF 3.9
Jingya Li,Mingyang Xue,Chen Xu,Nan Jiang,Yiqun Li,Yuding Fan,Yong Zhou,Yan Meng
Largemouth bass ranavirus (LMBRaV) is a highly lethal virus that has devastated the largemouth bass aquaculture sector. Therefore, it is imperative to develop therapeutic strategies for the control of this pathogen. In this work, the antiviral activity of Saikosaponin C was examined both in vitro and in vivo . According to the results of the in vitro antiviral activity assay, 30 mg/L of Saikosaponin C significantly down-regulated the expression of the LMBRaV major coat protein (MCP) gene in epithelioma papilloma cyprinid (EPC) cells, with an inhibitory rate exceeding 84%, and prevented LMBRaV replication in a dose-dependent manner. It also significantly limited its cytopathic effect (CPE), thereby playing a protective role on infected cells. Notably, Saikosaponin C has a certain preventative impact on the virus by influencing the mechanisms by which viral particles connect to cell receptors, which prevents LMBRaV from adsorbing on EPC cells. Simultaneously, Saikosaponin C also directly inactivated LMBRaV. The results of exploring the viral invasion cycle demonstrated that Saikosaponin C primarily exerted its antiviral effect during the middle stage (2–6 h) of viral infection. In addition, Saikosaponin C inhibited LMBRaV-induced apoptosis of EPC cells, maintained physiological cellular morphology and structure, and protected cells from loss of cellular morphology, formation of apoptotic vesicles, and cell fragmentation. Moreover, Saikosaponin C considerably improved the survival of virus-infected largemouth bass, according to the findings of in vivo investigations. In summary, Saikosaponin C demonstrated excellent anti-LMBRaV activity and holds considerable promise for development in the field of aquaculture.
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高影响因子
CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Liangcai Du,Qianqian Kong,Lichao Gong,Huachen Liu,Song Huang,Yunqi Xie,Zhenhua Yao
High entropy alloys (HEAs) exhibit distinctive core effects and excellent properties, presenting promising prospects for various applications, particularly as potential cermet adhesives. (Ti,W)C-HEA cermets were synthesized using vacuum sintering, employing mechanically alloyed CoCrFeNiTi HEA powder as a binder. The microstructure and mechanical properties of the produced cermets were systematically analyzed, with a particular focus on the effect of the HEA binder on the mechanical properties of the cermets. The findings indicated a decreasing trend in relative density, Rockwell hardness, and transverse rupture strength (TRS) of the cermets. Notably, the CM1 group ((Ti,W)C-30 wt% Co 20 Cr 20 Fe 20 Ni 35 Ti 5 ) demonstrated the most favorable overall properties, with values of 97.0 % for relative density, 83.2 HRA for Rockwell hardness, and 776.6 MPa for TRS. The phase transformation of HEAs at elevated temperatures was meticulously investigated using differential scanning calorimetry (DSC) and heat treatment. Combined with X-ray diffraction (XRD), the phase transformation of Co 20 Cr 20 Fe 20 Ni 25 Ti 15 and Co 20 Cr 20 Fe 20 Ni 15 Ti 25 , heat treated at increasing temperatures, is as follows: FCC + BCC (milled) → FCC + σ (700°C–1100 °C) → FCC (bulk).
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高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2025
·Vol. 36
·期 3
·1-13
·
IF 2.8
Li Caixia,Lu Peng,Ma Xiaoxuan,Zhang Kun,Li Chenglong
The rapid advancement of wearable electronic devices demands high-performance sodium-ion battery (SIB) cathode materials, particularly in terms of stability and electrochemical performance. Sodium super ionic conductor (NASICON)-type Na 3 V 2 (PO 4 ) 3 (NVP) has attracted significant attention due to its unique framework structure and high theoretical capacity. However, the inherently low electrical conductivity of NVP limits large-scale application. To address this issue, a novel NVP@C-rGO composite was synthesized using metal–organic frameworks (MOF) and reduced graphene oxide (rGO). The structures of these two forms of carbon enhance the charge transfer kinetics of NVP and provide two stress-buffering layers, thereby improving the structural stability of the material while significantly facilitating charge transport. Electrochemical testing confirmed the effectiveness of this strategy: at a current density of 500 mA g⁻ 1 , the NVP@C-rGO composite retained 71.1% of capacity after 600 cycles, compared to only 21.2% for unmodified NVP. Furthermore, due to the synergistic effect between rGO and MOF-derived NVP, the composite achieved a high specific capacity of 89.9 mAh g⁻ 1 under the same conditions, while NVP reached only 62.7 mAh g⁻ 1 . This significant improvement in performance, combined with the exceptional cycling stability and rate capability of the NVP@C-rGO||HC-rGO full cell, highlights the potential of the composite as a next-generation energy storage material for flexible and wearable electronic devices.
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高影响因子
Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Chen-Xuan Li,Wenhui Xu,Bai Li,Xiangyang Xu,Xian-Zhong Fu,Rui Deng,Feng Zhang,Yimin Sun,Kangping Cui
Waste cartons produced by e-commerce and the express delivery industry pose urgent environmental and social challenges, making their recycling a critical issue in recent years. In this study, a novel strategy for upcycling waste cartons into a Fenton-like chainmail catalyst, CoO x @C-P-8 (CoO x confined carbonaceous matrix), through a one-step pyrolysis process using waste cartons adsorbed cobalt nitrate was proposed. The catalytic activity of CoO x @C-P-8 in activating peroxymonosulfate (PMS) for the removal of tetracycline hydrochloride (TCH) was thoroughly evaluated. The results indicated that the combination CoO x @C-P-8 (0.3 g/L) and PMS (1.0 mM) could remove 92 % of TCH within 60 min. Mechanistic studies revealed that both singlet oxygen ( 1 O 2 ) and radicals (i.e. SO 4 •− , O 2 •− and HO • ) contributed to TCH removal, with cobalt-loading, N-doping, and the defective graphitic structure identified as the key governing factors. The unique chainmail structure of CoO x @C-P-8 endowed it with pronounced resistance to interference from ions (Cl − , NO 3 − , HCO 3 − , H 2 PO 4 − , K + , Mg 2+ , and Na + ) and pH variations (pH 3.0–11.0). Furthermore, the high environmental viability of CoO x @C-P-8, evidenced by ease of magnetic separation and simple catalyst regeneration, was demonstrated. This work may offer a feasible strategy for upcycling waste cartons and also contribute substantively to the advancement of wastewater decontamination.
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高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2025
·
IF 3.9
Xuying Liu,Min Zou,Yehao Yu,Yuanrui Hai,Jinyan Huang,Yunchang Fan,Yulong Zhang,Yujing Weng,Yuhe Liao
Glycolic acid (GA), a versatile compound widely used in pharmaceuticals, cosmetics, and biodegradable polymers, requires efficient and sustainable synthesis methods to meet industrial demands. This study investigates the selective oxidation of glycolaldehyde (GD) and ethylene glycol (EG) to GA over a carbon-supported platinum (Pt/C) catalyst under alkali-free conditions. Complete GD conversion with exceptional GA selectivity (99.8%) was achieved under mild conditions (30 °C, 2.5 MPa air), while EG oxidation exhibited moderate conversion (∼60%) with >90% GA selectivity. Kinetic analysis revealed distinct oxygen pressure dependencies: GD oxidation exhibited strong oxygen sensitivity, as oxygen adsorption and activation were rate-determining, whereas EG oxidation was predominantly governed by substrate concentration due to the oxygen saturation on the Pt/C surface. Mechanistic studies identified GD as a key intermediate in EG oxidation, with overoxidation pathways limiting GA selectivity at higher temperatures and concentrations. Catalyst characterization demonstrated high Pt dispersion, stable surface chemistry, and structural durability, contributing to its superior performance. This work provides a green, efficient pathway for GA production, offering valuable insights into catalyst design and process optimization for sustainable chemical manufacturing.
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高影响因子
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