FOOD CHEMISTRY
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2024
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IF 8.5
Yanke Lu,Pengfei Li,Liuliu Cheng,Lianfeng Ai,Jiankun Cao,Hongyuan Yan
Halogenated carbazoles (HCZs) are prevalent in sediments, pose a risk of entering the human food chain via lotus roots. However, starch, protein, and fat in lotus root complicate determination of HCZs in this food. This study introduces a straightforward, sensitive, and rapid method for detecting four HCZs in lotus roots. The method employs a conical monolithic extraction column (MEC) containing chitosan-glutaraldehyde-graphene oxide aerogel (CS-GA-GOA) material. The CS-GA-GOA − MEC successfully achieved extraction of four HCZs in spiked lotus root samples in under 5 min. The method was rapid (15 min) compared with alternatives, as well as being sensitivity (0.08–0.27 ng/g), accurate (89.7 %–104.2 %), and more cost-effective. This work contributes to the exploration of advanced adsorbents but also broadens the applicability of graphene oxide aerogels in extraction processes, paving the way for the development of rapid and accurate analytical methods for HCZs in foods.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Min Wang,Yajie Yue,Xiaoning Wei,Jinyuan Zhang,Xinyuan Bi,Liyan Jia,Xu Jing
Strobilurin fungicides are widely used pesticides globally; however, their residues pose a risk to environmental safety and human health. This study aimed to develop a rapid and green method for detecting strobilurin fungicide residues. Chitosan and magnetic deep eutectic solvent-based emulsive liquid-liquid microextraction method combined with high-performance liquid chromatography was developed to determine strobilurin fungicides in water samples. A high-concentration oil-in-water emulsion containing chitosan solution and extractant was formulated, followed by the addition of samples to form a low-concentration oil-in-water emulsion to complete the rapid pretreatment, therefore solving the limitation of emulsive liquid-liquid microextraction in the inapplicability of extractants. Traditional microextraction required toxic solvents and complex equipment to facilitate the dispersion of extractants, whereas this study used only chitosan solution to aid in emulsifying extractants. The new green magnetic deep eutectic solvent synthesized by tetraoctylammonium bromide, ferric chloride, and oleic acid was used instead of toxic extractants. An external magnetic field assisted the extractant phase collection, which shortened the separation time. Under optimal conditions, the recovery of this method was 83.3 %–107.4 %, the limit of detection was 0.0010–0.0021 mg L −1 , and the coefficient of determination was >0.994. This rapid, green, simple, and efficient chitosan-based microextraction method could detect strobilurin fungicide residues in water samples because of its enhanced compatibility with hydrophobicity extractants.
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COMPOSITES PART B-ENGINEERING
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2024
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IF 12.7
Ying Han,Mouyuan Sun,Xingchen Lu,Kailei Xu,Mengfei Yu,Huayong Yang,Jun Yin
In neural tissue engineering , biomaterial scaffolds that have high conductivity and customized structures are crucial in promoting nerve regeneration. Poly(3,4-ethylenedioxythiophene) (PEDOT) has emerged as a promising conductive polymer with excellent chemical stability and biocompatibility. However, traditional three-dimensional (3D) printing of PEDOT-based conductive scaffolds faces challenges in limited printing resolution, poor solubility, and brittleness of conductive materials . Herein, digital light processing (DLP) printing was used to fabricate complex hydrogel structures using gelatin methacryloyl (GelMA) and chitosan (CS) while incorporating PEDOT nanoparticles through interfacial polymerization to create conducting pathways within a hydrogel structure. The integration of PEDOT significantly enhanced the electrical conductivity and mechanical properties of the GelMA/CS hydrogel while preserving printed details. The GelMA/CS-PEDOT hydrogel promoted cell proliferation and facilitated axon outgrowth of PC12 cells and Schwann cells during in vitro culture. Moreover, in vitro direct current electrical stimulation promoted axon elongation of PC12 cells cultured on a conductive substrate. In vivo studies used a conductive nerve conduit to repair a 10-mm rat sciatic nerve defect, validating the efficacy of GelMA/CS-PEDOT scaffold in peripheral nerve injury repair. These findings highlight the significant potential of conductive GelMA/CS-PEDOT hydrogel in the field of neural tissue engineering.
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Acta Biomaterialia
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2024
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IF 9.4
Kaidi Ding,Wenlong Cong,Ying Liu,Changtong Song,Haoyang Mi,Chuntai Liu,Yuhong Ma,Changyu Shen
Endoscopic surgery is an effective and common clinical practice for chronic sinusitis. Nasal packing materials are applied in nasal surgery to prevent hemorrhage and promote wound healing. In this study, a degradable polyurethane foam dressing is successfully developed as a promising nasal packing material with good biocompatibility and antibacterial capability. Specifically, quaternized chitosan (QCS) serves as the crosslinker instead of polyols to offer polyurethane foam (PUF-QCS) antibacterial capability. The PUF-QCS2.0 % (with 2.0 wt% QCS) exhibits satisfactory liquid absorption capacity (19.4 g/g), high compressive strengths at both wet (14.5 kPa) and dry states (7.7 kPa), and a good degradation rate (8.3 %) within 7 days. Meanwhile, PUF-QCS2.0 % retains long-term antibacterial activity for 7 days and kills 97.3 % of S. aureus and 91.8 % of E. coli within 6 hours in antibacterial testing. Furthermore, PUF-QCS2.0 % demonstrates a positive hemostatic response in the rabbit nasal septum mucosa trauma model by reducing hemostatic time over 50.0 % and decreasing blood loss up to 76.1 % compared to the commercial PVA nasal packing sponge. Importantly, PUF-QCS also exhibits a significant antibacterial activity in nasal cavity. This nasal packing material has advantages in post-surgery bleeding control and infection prevention. Statement of Significance The performance of a nasal packing sponge requires good mechanical properties, fast and high liquid absorption rate, effective degradability and strong antibacterial activity. These features are helpful for improving the postoperative recovery and patient healing. However, integrating these into a single polyurethane foam is a challenge. In this study, quaternized chitosan (QCS) is synthesized and used as a chain extender and antibacterial agent in preparing a degradable polyurethane foam (PUF-QCS) dressing. PUF-QCS undergoes partial degradation and exhibits effective broad-spectrum antibacterial activity in 7 days. The reduction of postoperative bleeding and infection observed in the animal experiment further demonstrates that the PUF-QCS developed here outperforms the existing commercial nasal packing materials.
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CARBOHYDRATE POLYMERS
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2015
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IF 4.074
Sha Peng,Kunyan Hao,Feng Han,Zheng Tang,Beibei Niu,Xu Zhang,Zhen Wang,Song Hong
The removal of bisphenol-AF (BPAF) from aqueous solutions onto chitosan-modified zeolite (Ch-Z) in the absence and presence of sodium cholate (NaC) was investigated. It was found that NaC significantly increased the adsorption capacity of Ch-Z for BPAF. At an initial concentration of 100 μmol/L, the removal of BPAF by adsorption onto Ch-Z with NaC was more than ninefold higher than without NaC, and the maximum removal was achieved at a Ch-Z dosage of 1 g/L with a NaC concentration of 1.68 mmol/L. Besides, batch studies were performed to evaluate the effects of various experimental parameters on the removal of BPAF. Kinetic studies and adsorption isotherms indicated that the adsorption process of BPAF onto Ch-Z with NaC could be expressed by a pseudo second-order model and the Freundlich isotherm model, respectively. For the enhanced removal, an interaction mechanism was proposed involving the co-effect of BPAF and NaC adsorbed onto Ch-Z.
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MATERIALS LETTERS
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2015
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IF 2.489
Zhang Leilei,Li Hejun,Li Kezhi,Liu Shoujie,Zhang Yulei,Yao Pei,Zhang Wenqi,Chen Guanzheng
A multi-layer coating composed of SiC inner-layer and Mg and F co-substituted hydroxyapatite/chitosan hybrid out-layer for carbon fibers has been synthesized using a combination method of chemical vapor deposition , electrochemical deposition and ion exchange method. The morphology, microstructure and in-vitro bioactivity of the multi-layer coating are analyzed. The results show that the SiC inner-layer exhibits a squamous shape. Mg and F co-substituted hydroxyapatite/chitosan hybrid out-layer covers the SiC inner-layer coated carbon fiber entirely and uniformly with a flat structure. The multi-layer coating could induce the precipitation of particle-shaped apatite crystals with Ca/P molar ratios of 1.34–1.51 on its surface in simulated body fluid. The multi-layer SiC/Mg and F co-substituted hydroxyapatite/chitosan coated carbon fibers should have potential application for tissue engineering.
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APPLIED SURFACE SCIENCE
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2015
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IF 2.711
Kaihang Chen,Zuguang Shen,Jiwen Luo,Xiaoying Wang,Runcang Sun
There is an urgent need to develop a highly sensitive detection system for detecting trace amounts of food contaminants. In this study, optimal synthesis of silver nanoparticles (Ag NPs) with stable and narrow size distribution in the range of 15–25 nm was performed under microwave irradiation, using quaternized chitosan (QCS) as reducing and stabilizing agent. The results showed that the ratio of QCS to [Ag(NH 3 ) 2 ] + , reaction temperature, irradiation time, the degree of substitution ( DS ) and molecular weight ( Mw ) of QCS had obvious effects on the formation, particle size and size distribution of Ag NPs. In addition, utilizing QCS/Ag NPs composite as SERS substrate, tricyclazole and Sudan I could be rapidly and sensitively detected with the limit of detection (LOD) as low as 50 ppb and 10 ppm, respectively. Compared with previously reported works, our detection system are of great stability and operability. The QCS was coated on the surface of Ag core, avoiding aggregation of Ag NPs and creating hot spots, in turn, providing superior amplification of SERS. Thus, it is believed that the QCS/Ag NPs composite could be considered as an ideal SERS-active substrate for detection of food contaminants.
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REACTIVE & FUNCTIONAL POLYMERS
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2016
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IF 2.725
Guanghua He,Wanwan Ke,Xiang Chen,Yahui Kong,Hua Zheng,Yihua Yin,Weiquan Cai
Quaternary ammonium chitosan- g -poly(acrylic acid- co -acrylamide) superabsorbent hydrogels were successfully synthesized from acrylic acid (AA), acrylamide (AM) and quaternary ammonium chitosan with high substitution degree. They were prepared using potassium persulfate (KPS) as an initiator and N , N ′-methylenebisacrylamide (MBA) as a crosslinker respectively. The structure and morphology of the superabsorbent hydrogel were characterized by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The water absorbency and antibacterial activities of the superabsorbent hydrogels against Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) were investigated. The introduction of quaternary ammonium chitosan made the antibacterial activity improve. The crosslinker, initiator and AM contents had certain influences on the water absorbency as well as the antibacterial activity against E. coli . The AM could enhance the hydrogel strength apparently. In addition, the AM (the content was 10 wt%) could increase the water absorbency in 0.9 wt% NaCl solution obviously. The superabsorbent hydrogel also had pH sensitive property.
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ACS Sustainable Chemistry & Engineering
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2016
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IF 5.267
Jianhong Ma,Guiyin Zhou,Lin Chu,Yutang Liu,Chengbin Liu,Shenglian Luo,Yuanfeng Wei
A ethylenediaminetetra-acetic acid (EDTA) cross-linked chitosan and N,N-methylenebis(acrylamide) (MBA) cross-linked polyacrylamide based double network hydrogel was successfully synthesized via a two-step method and then employed for heavy metal ion adsorption. Various adsorption conditions, such as pH, ionic strength, adsorbent dosage, and contact time were investigated. CTS/PAM gel have a theoretical maximum Cd(II), Cu(II), and Pb(II) sorption capacities of 86.00, 99.44, and 138.41 mg/g, respectively, at experimental conditions. The adsorption process of CTS/PAM gel on the heavy metal ion was identified to be endothermic and follows an ion-exchange reaction. The application of this gel adsorbent was demonstrated using practical industrial effluent. We found that it could effectively treat practical wastewater with all kinds of heavy metals. At an adsorbent dosage of 8 g/L, the total metal ions concentration declined from 448.5 to 5.0 mg/L. Simultaneously, the CTS/PAM gel exhibited remarkable mechanical strength and good recyclability. This study shows that CTS/PAM gel offers great potential for practical application in the removal of heavy metal ions from contaminated aquatic systems.
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JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
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2017
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IF 2.764
Haoxiang Zhong,Jidian Lu,Aiqin He,Minghao Sun,Jiarong He,Lingzhi Zhang
Carboxymethyl chitosan/poly (ethylene oxide) (CCTS/PEO) composite is firstly reported as a water soluble binder for the application of 5 V LiNi 0.5 Mn 1.5 O 4 cathode in Li-ion batteries. Both CCTS and PEO show a high electrochemical oxidation potential of above 5.0 V (vs. Li/Li + ). The electrochemical performances of LiNi 0.5 Mn 1.5 O 4 (LNMO) cathodes with CCTS/PEO composite binders of different mass rates are investigated, it is found that LiNi 0.5 Mn 1.5 O 4 cathode with an optimized CCTS/PEO (85/15, w/w) composite exhibits a slightly better cycling performance than that of polyvinylidene fluoride (PVDF), retaining 81.4% capacity as compared with 79.8% for PVDF at 0.5C rate after 200 cycles. LNMO with PEO/CCTS (85/15, w/w) exhibited the better rate capability than that of PVDF. These results demonstrate that CCTS/PEO composite can be potentially used as a water-soluble binder for 5 V LNMO cathode.
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INTERNATIONAL JOURNAL OF MINERAL PROCESSING
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2017
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IF 1.561
Cheng Zhang,Cheng Liu,Qiming Feng,Yanfei Chen
Utilization of N -carboxymethyl chitosan (N-CMCh) to limit the detrimental effect of serpentine on the flotation of pyrite is presented in this work. Flotation results show that the presence of hydrophilic serpentine slimes results in lower recoveries of the valuable pyrite. Utilization of N -carboxymethyl chitosan can limit the detrimental effect of serpentine on the flotation of pyrite. Zeta potential measurements illustrate that N-CMCh is with negative charge and the electrostatic interaction between serpentine and N-CMCh is occurred at pH 8.5, then the serpentine zeta potential will be changed from positive to negative, the electro-steric attraction converts into electro-steric repulsion between pyrite and serpentine and the pyrite recovery is improved.
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EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
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2016
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IF 3.975
Yukun Wu,Jing Wu,Jing Cao,Yajie Zhang,Zhe Xu,Xiuyi Qin,Wei Wang,Zhi Yuan
Chitosan is one of the most important and commonly used natural polysaccharides in drug delivery for its biocompatible and biodegradable properties. However, poor blood circulation of the chitosan nanoparticles due to their cationic nature is one of the major bottlenecks of chitosan-based drug delivery systems. To address this problem, a versatile platform based on poly(acrylic acid) (PAA) coated ionically cross-linked chitosan/tripolyphosphate nanoparticles (CTS/TPP-PAA NPs), is reported. The zeta potentials of CTS/TPP and CTS/TPP-PAA NPs are approximately 33 mV and −25 mV, respectively. CTS/TPP NPs quickly aggregate in PBS (phosphate buffered saline) and DMEM (Dulbecco’s modified Eagle’s medium). Conversely, CTS/TPP-PAA NPs exhibit excellent colloidal stability in plasma solution for more than 24 h. The PAA coating also endows CTS/TPP-PAA NPs with decreased protein adsorption capacity and improved buffering capacity. More importantly, the residual carboxyl and amino groups on CTS/TPP-PAA NPs provide abundant reactive sites for further functional modifications. Therefore, the CTS/TPP-PAA NPs reported here may be useful as an alternative drug delivery system.
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