Journal of Materials Chemistry A
·
2025
·
IF 9.5
Guangsen Tian,Shouzheng Li,Shaojia Song,Hongxi Zhao,Linfeng Zhang,Huadong Wu,Ye Luo,Jianding Li,Jia Guo,Qun Yi
The rational design of D–A type polymeric photocatalysts using triphenylamine (TPA) as the electron donor (D) and a benzothiadiazole derivative (BTDO) as the electron acceptor (A) is investigated. To optimize photocatalytic hydrogen evolution, we systematically enhanced the electron-donating capability by incorporating oligothiophene linkers of different lengths, monothiophene (T), bithiophene (DT), and terthiophene (TT), between the TPA and BTDO units. Comprehensive characterization revealed that the number of thiophene rings significantly affects both the photophysical and electrochemical properties of the polymers, thereby directly affecting photocatalytic activity. The results demonstrate that introducing thiophene oligomers significantly improves performance, with the terthiophene (TT) linker proving exceptionally advantageous. The TPA-TT-BTDO polymer exhibits a substantially broadened visible light absorption range, a reduced bandgap, and most critically, highly efficient suppression of photogenerated charge carrier recombination. This enhancement is attributed to the unique coplanar conformation enforced by the TT unit, which minimizes the dihedral angle between TPA and BTDO, facilitating intramolecular charge transfer. TPA-TT-BTDO achieved an outstanding photocatalytic hydrogen evolution rate of 101.2 mmol h−1 g−1 under visible light (λ ≥ 420 nm) at 10 °C without noble metal co-catalysts. Remarkably, its activity further increased to 125 mmol h−1 g−1 under natural sunlight irradiation. Systematic analysis revealed that longer thiophene chains induce a bathochromic shift, diminish PL intensity, yet improve photoelectrochemical properties and charge transfer efficiency. This work validates the molecular design strategy of precisely controlling oligothiophene chain length to modulate the band structure and electronic properties of D–A polymers. The superior performance of TPA-TT-BTDO stems synergistically from its extended light harvesting, efficient charge separation, and rapid interfacial transfer. These findings may provide crucial insights and practical guidance for developing high-efficiency polymeric photocatalysts through targeted molecular engineering.
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TALANTA
·
2025
·
IF 6.1
Jiangbin Xu,Wei Yang,Yuanfa Liu
The development of rapid and sensitive detection methods for propyl Gallate (PG) is crucial due to its significant threats to human health and the environmental safety. Here, B, N co-doped carbon dots (BN-CDs) were designed by employing 5-boronoisophthal and o -phenylenediamine as precursors to enable fluorimetric and colorimetric dual-mode detecting of PG. Specifically, the presence of PG could result in a decrease in fluorescence intensity, while simultaneously leading to the formation of a distinctive tawny complex that exhibited a pronounced colorimetric response. The fluorimetric and colorimetric mode demonstrated dependable selectivity and exceptional sensitivity, with detection limits of 0.12 μg/mL and 0.27 μg/mL, respectively. The fluorescence sensing mechanism was confirmed to be attributed to the static quenching effect (SQE) through both experimental results and density functional theory (DFT) analysis, indicating that the "ON-OFF" progress could be ascribed to the formation of a non-luminescent substance. Additionally, the application of actual samples detection demonstrated outstanding self-calibration capabilities and achieved satisfactory recovery rats ranging from 94.0 % to 112.0 %. Furthermore, the smartphone-assisted sensing system exhibited the capability to conveniently and visually assess PG levels by accurately distinguish subtle variations in color. The study presents an effective dual-mode sensing approach for rapid and accurate detection of PG, which offers significant benefits in reducing the probability of PG exposure.
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RSC Advances
·
2016
·Vol. 6
·期 105
·103843-103850
·
IF 3.289
Aitang Zhang,Aihua Li,Yao Wang,Mengli Liu,Hongjing Ma,Zhongqian Song,Jingquan Liu
Mesoporous carbon nanoparticles (MCNs) were prepared through a series of annealing procedures using well-controlled diblock copolymer micelles as precursors. The micelles were prepared from poly(acrylonitrile)-block-poly(methylmethacrylate) (PAN-b-PMMA), and synthesized via reversible addition–fragmentation chain transfer (RAFT) polymerization. The RAFT-controlled synthesis of block copolymer, PAN-b-PMMA was conducted either in solution or emulsion conditions. It was found that micelles with well-defined morphology could be directly formed from the emulsion polymerization. The as-synthesized micelles containing hydrophilic PAN corona as the carbon source and hydrophobic PMMA core as the sacrificing template underwent a microphase-separation process to form a nanostructure at 250 °C, followed by carbonization at 800 °C to afford MCNs. What's more, the MCNs based supercapacitor exhibited a good capacitance value of 220 F g−1 and an excellent cycling performance of 91% capacitance retention after 10 000 cycles. The as-prepared MCNs are envisioned to provide broad practical applications in the fields of energy storage and nanotechnology.
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ANALYTICA CHIMICA ACTA
·
2015
·
IF 4.513
Haiyun Zhai,Zihao Su,Zuanguang Chen,Zhenping Liu,Kaisong Yuan,Lu Huang
A method was developed to sensitively determine phloxine B in coffee bean by molecularly imprinted polymers (MIPs) coated graphene oxide (GO) solid-phase extraction (GO-MISPE) coupled with high-performance liquid chromatography and laser-induced fluorescence detection (HPLC–LIF). The GO-MISPE capillary monolithic column was prepared by water-bath in situ polymerization, using GO as supporting material, phloxine B, methacrylic acid (MAA), and ethylene dimethacrylate (EDMA) as template, functional monomer, and cross-linker, respectively. The properties of the homemade GO-MISPE capillary monolithic column, including capacity and specificity, were investigated under optimized conditions. The GO-MIPs were characterized by scanning electron microscopy (SEM) and Fourier transform-infrared spectroscopy (FT-IR). The mean recoveries of phloxine B in coffee bean ranged from 89.5% to 91.4% and the intra-day and inter-day relative standard deviation (RSD) values all ranged from 3.6% to 4.7%. Good linearity was obtained over 0.001–2.0 μg mL −1 ( r = 0.9995) with the detection limit (S/N = 3) of 0.075 ng mL −1 . Under the selected conditions, enrichment factors of over 90-fold were obtained and extraction on the monolithic column effectively cleaned up the coffee bean matrix. The results demonstrated that the proposed GO-MISPE HPLC–LIF method can be applied to sensitively determine phloxine B in coffee bean.
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JOURNAL OF APPLIED POLYMER SCIENCE
·
2016
·Vol. 134
·期 8
·
IF 1.866
Tian Zhong,Yang Jiao,Lingling Guo,Jiamin Ding,Zhuping Nie,Lianjiang Tan,Ran Huang
To address concern of the dispersion property of hydrophilic drugs of excess dose loaded in a hydrophobic poly(lactic acid) (PLA) matrix, this work developed a PLA and PLA -b -polyethylene glycol (PEG) composite scaffold ( ) and studied its carrier properties for aspirin as a model hydrophilic drug. The porous functional scaffolds were prepared from PLA and PLA -b -PEG solutions with the dose of 5, 10, and 15 wt % aspirin preloaded. The products and control samples of pure PLA with the same loading amount for comparison were characterized by scanning electron microscopy and X-ray diffraction to examine the miscibility and porous structure. Rapid degradations in a strongly basic solution were performed to determine the actual loading amount and the encapsulation ratio. The in vitro release in phosphate buffer saline (PBS) at 37.5 °C indicated that the addition of amphiphilic block polymer may efficiently enhance the dispersion property and stabilize the release of hydrophilic drugs, especially with a high loading dose. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134 , 44489.
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Bioengineered
·
2022
·
IF 6.832
Meng-Hui Zhang,Jun Liu
Liver hepatocellular carcinoma (LIHC) is the most common type, comprising 75–85% of all liver malignancies. We investigated the roles of cleavage stimulation factor 2 (CSTF2) in LIHC and explored the underlying mechanisms. CSTF2 expression and its association with LIHC patient survival probability were analyzed with The Cancer Genome Atlas. CSTF2 expression in LIHC cells was assessed using western blot and quantitative real-time PCR. Alterations in CSTF2 expression were induced by cell transfection. Cell colony formation, apoptosis, proliferation, invasion, and migration were assessed using colony formation, flow cytometry, 5-ethynyl-2ʹ-deoxyuridine, and transwell assays. Pathway enrichment analysis was performed using gene set enrichment analysis (GSEA). The expression of apoptosis-, metastasis-, and pathway-associated factors was determined via western blot. The pathway rescue assay was further performed using 740Y-P or Wortmannin. CSTF2 upregulation was observed in LIHC tissues and cells. Patients with high CSTF2 expression had a lower probability of overall survival. CSTF2 overexpression enhanced colony formation, proliferation, invasion and migration, while repressing apoptosis in LIHC cells. GSEA revealed that CSTF2 was mainly enriched in the phosphatidylinositol 3′-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) pathway. Western blot analysis proved that CSTF2 overexpression activated this pathway. CSTF2 knockdown yielded the opposite effects. 740Y-P, a PI3K activator, reversed the CSTF2 knockdown-triggered effects on cell proliferation, apoptosis, invasion, and migration. Moreover, Wortmannin, a PI3K inhibitor, also reversed the CSTF2 overexpression-induced effects on cell proliferation, apoptosis, invasion, and migration. These results indicated that CSTF2 overexpression might exacerbate the malignant phenotypes of LIHC cells via activation of PI3K/AKT/mTOR pathway.
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高影响因子
PEST MANAGEMENT SCIENCE
·
2026
·
IF 4.2
Yang Yang,Yu-Xin Zhou,Le-Yao Jia,Xin-Yang Song,Ya-Jie Lai,Si-Yuan Liu,Su-Yan Wang,Pedro Laborda,Xin-Chi Shi
BACKGROUND The spoVF operon, encoding the dipicolinic acid (DPA) synthase, is critical for sporulation in Bacillus subtilis . A recent study suggested that spoVF expression in vegetative cells promotes biofilm formation, yet the detailed regulatory pathways and the underlying metabolic connections remain to be fully elucidated. RESULTS In this study, deletion of spoVF subunits spoVFA and spoVFB severely reduced DPA synthesis, downregulated mreB gene expression, and impaired biofilm formation, with mutant ΔA showing stronger effects than mutant ΔB. Although wild type B. subtilis 168 cells exhibited rod shape, double mutant ΔAΔB cells were spherical. In the MT strain, engineered for enhanced spoVF expression during vegetative growth, the upregulation of key TCA cycle genes (e.g., citC ) and glutamate synthesis genes (e.g., gltA ) was observed. This metabolic reprogramming was accompanied by the promotion of Spo0A phosphorylation. The activated Spo0A~P then inhibited the SinR and AbrB repressors, which led to the activation of the eps and tasA biofilm operons. The MT strain showed superior stress tolerance to high temperature (42 °C), salt, acidic and alkaline pH, and UV-A and UV-B radiation. Additionally, the MT strain exhibited higher nutrient competition ability, and in vitro and in vivo antifungal activities against the sweet potato ( Ipomoea batatas L. Lam) storage root pathogen Ceratocystis fimbriata compared to mutant ΔA, ΔB, and ΔAΔB strains. CONCLUSIONS This study elucidates how the spoVF operon links the central metabolic pathways with B. subtilis cell morphology and biofilm formation, offering a novel target for engineering advanced Bacillus -based biocontrol agents. © 2026 Society of Chemical Industry.
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JOURNAL OF MOLECULAR LIQUIDS
·
2018
·
IF 4.513
Ahmed A. Fadhil,Anees A. Khadom,Hongfang Liu,Chaoyang Fu,Junlei Wang,Noor A. Fadhil,Hameed B. Mahood
A study on the corrosion inhibition of N80 steel in 0.5 M HCl acid with ( S )‑ 6 ‑ Phenyl ‑ 2 , 3 , 5 , 6 ‑ tetrahydroimidazo [ 2 , 1 ‑ b ] thiazole was undertaken by conducting electrochemical, weight loss, surface morphology , and FTIR measurements. The inhibition efficiency was found to exceed 95%. An excellent inhibitor performance was attained when a spontaneous layer was formed and adsorbed chemically on the surface of steel. The adsorption of inhibitor followed Langmuir adsorption isotherm . Meanwhile, the inhibitor was categorized as a mixed – type one. FTIR and surface morphology analysis was conducted to validate the results, whereas quantum chemical calculation was applied for justifying the inhibition process.
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高影响因子
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
·
2026
·Vol. 47
·期 1
·118754
·
IF 6.3
Junyao Wu,Sai Liu,Shenxiang Luo,Jinwei Guo,Haonan Shi,Fan Zhang,Wang Zhu
High-entropy A 6 B 2 O 17 (A = Hf, Zr; B = Ta, Nb)/8YSZ double-layer ceramic coatings with three compositions are fabricated by atmospheric plasma spraying (APS). Thermal cycling tests are performed at 1150 °C with a 5 min heating hold followed by 5 min air cooling, while isothermal oxidation tests are performed at 1150 °C. Among the three coatings, H 3 Z 1 T 2 N 1 coating exhibits the longest thermal cycling lifetime (1823 ± 153 cycles), followed by the H 1 Z 1 T 2 N 1 coating (1123 ± 136 cycles) and H 1 Z 3 T 2 N 1 coating (826 ± 114 cycles). After 180 h oxidation, the thermally grown oxide (TGO) thicknesses are 5 μm, 5.6 μm, and 6.6 μm, respectively. The H 3 Z 1 T 2 N 1 coating possesses the lowest oxidation rate constant ( k p = 0.1263 μm 2 ·h −1 ). This superior performance is attributed to dense vertical cracks induced by higher thermal expansion, which relieve thermal stress, suppress oxygen ingress, and delay interfacial failure.
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JOURNAL OF SEPARATION SCIENCE
·
2026
·Vol. 49
·期 7
·e70489
·
IF 3.6
Jiaheng Yan,Yifan Xu,Yihui Chen,Zhicheng Bai,Jianfeng He,Meikang Lei,Xiaoqiang Qiao,Tingting Wang
Quantifying hydrophilic B vitamins (B1 [(thiamine], B2 [riboflavin], and B3 [nicotinic acid]) in complex functional food matrices presents a significant challenge. Conventional sorbents, such as C18, often exhibit poor retention and low recoveries (50%–60%) due to weak hydrophilic interactions. To efficiently extract these target analytes from functional foods, a new sorbent with tailored hydrophilic affinity has been developed by incorporating Co-cyromazine complexes onto halloysite nanotubes. This composite was employed as the sorbent for a spin-tip solid-phase extraction method, which was coupled with liquid chromatography-tandem mass spectrometry analysis. Following comprehensive optimization and validation, the method demonstrates simplicity, accuracy, sensitivity, and cost-effectiveness. It requires only 10 mg (or 10 µL) of functional food sample, while delivering high recoveries (81.3%–107.8%) with good precision (relative standard deviations ≤10.7%). The limits of detection ranged from 0.4 to 2.5 ng/mL in liquid matrices and from 0.7 to 8.7 ng/g in solid matrices. Practical applicability was confirmed through the successful quantification of vitamins B1, B2, and B3 in various commercial functional foods. Consequently, the developed method provides a reliable and promising analytical tool for the determination of B vitamins, with the potential for extension to other hydrophilic analytes in biological and food matrices.
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Reaction Kinetics Mechanisms and Catalysis
·
2026
·
IF 2.1
Sun Bai,Zhang Zhilong,Zhou Taoyou,Hong Guiyun,Wang Yun,Pan Fakang,Huang Hao,Bao Lining,Yi Mingjian,Zhu Shuguang
Zeolitic imidazolate framework-L (ZIF-L)-derived cobalt–nickel layered double hydroxide (CoNi-LDH) nanosheets are developed as a heterogeneous activator of peroxymonosulfate (PMS) for Rhodamine B (RhB) degradation. The optimized CoNi-LDH/PMS system achieves 99% RhB removal within 12 min along with an apparent rate constant ( k obs ) of 0.55 min −1 , while total organic carbon removal reaches approximately 34% at 12 min. The catalyst also retains activity toward several representative organic contaminants, during five reuse cycles, and in tap and lake water matrices. Quenching experiments, electron paramagnetic resonance, nitroblue tetrazolium probing, Fourier transform infrared spectroscopy, and X-ray photoelectron spectroscopy collectively indicate that PMS activation is dominated by a singlet oxygen ( 1 O 2 )-mediated non-radical pathway, with radical species making minor contributions. The results further suggest that Co/Ni redox cycling promotes PMS activation, while lattice-oxygen-related surface changes would participate in interfacial electron transfer. This study highlights a ZIF-L-derived bimetallic LDH architecture that couples rapid PMS activation with preferential 1 O 2 generation, and provides a basis for further evaluation in complex water matrices.
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Plants-Basel
·
2026
·Vol. 15
·期 9
·1408
·
IF 4.7
Yangmin Zhu,Zengrong Huang,Junyi Wen,Jiangming Wei,Ke Liu,Yuan Su,Yunfeng Liu,Shengchao Ge
Papain-like cysteine proteases (PLCPs) are central immune hubs frequently targeted by pathogen effectors. Sugarcane smut, caused bySporisorium scitamineum, threatens global sugarcane yield, yet effector manipulation of host PLCPs remains unclear. Genome-wide analysis ofSaccharum spontaneumAP85-441 identified 61 PLCP-encoding genes, which were classified into nine conserved subfamilies. Among these, ScRD21A, a member of the RD21 subfamily, was prioritized for functional characterization. Two Pit2 homologs, SsPit2A and SsPit2B, were identified fromS. scitamineum. Yeast two-hybrid, BiFC and pull-down assays demonstrated that both effectors interact with ScRD21A, and that this interaction depends on a conserved LXRR motif within their PID14-like region. In total protein extracts fromNicotiana benthamiana, co-expression of SsPit2A or SsPit2B reduced ScRD21A-associated cysteine protease activity. Transient expression of ScRD21A enhanced flg22-induced ROS production, attenuatedPst DC3000-induced hypersensitive response-associated necrosis, and increased resistance toBotrytis cinerea. Together, these results support a conserved PLCP-targeting strategy in smut fungi and identify the ScRD21A–SsPit2A/B module as a tractable framework for studying effector–protease interactions relevant to sugarcane smut.
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高影响因子
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