Journal of Materials Chemistry B
·
2015
·Vol. 3
·期 13
·2685-2697
·
IF 4.726
Xinyu Hu,Wei Wei,Xiaoliang Qi,Hao Yu,Liandong Feng,Junjian Li,Shiming Wang,Jianfa Zhang,Wei Dong
Salecan is a novel water-soluble extracellular β-glucan produced by a salt-tolerant strain Agrobacterium sp. ZX09. Salecan is suitable for the fabrication of hydrogels for biomedical applications due to its excellent physicochemical and biological properties. In this paper, a series of pH-sensitive hydrogels were prepared in aqueous solution by the graft copolymerization of Salecan and acrylic acid (AA) using N,N′-methylene diacrylamide as a crosslinker for controlled drug delivery. The structure and thermal stability of the resulting hydrogels were characterized by FT-IR, XRD and TGA. By SEM analysis, freeze-dried hydrogels displayed an interconnected porous structure with tunable pore size in the range of 23.2–90.3 μm. The swelling behavior of the hydrogels was shown to be highly dependent on the environmental pH, salt type and concentration, as well as the contents of Salecan and BAAm. They are almost unswellable at pH 1.2 and swollen extensively at pH 6.86. Meanwhile, the increase in the content of hydrophilic Salecan could enhance the swelling ratio, whereas the presence of more BAAm reduced the swelling capacity but promoted the water retention to some extent. Rheological tests revealed that storage modulus G′ was strongly influenced by the crosslink density of the obtained hydrogel network. Especially, doxorubicin (DOX) as a model anti-cancer drug was very efficiently loaded into the negatively charged hydrogels (up to 69.4 wt%) through electrostatic interactions. More importantly, the release of DOX from this intelligent system exhibited pH-responsive behavior and a sustained release pattern. For SPA2, the cumulative release profile showed a low level of drug release (about 12.3 wt% in 24 h) at pH 7.4, and was significantly accelerated at pH 4.0 (over 40 wt% in 6 h). Cytotoxicity experiments confirmed that all blank hydrogels were non-toxic to A549 cells, while DOX released from the drug-loaded hydrogels remained biologically active and had the capability to kill cancer cells. The preliminary results clearly suggested that the Salecan-g-PAA hydrogels may be promising carriers for controlled drug delivery.
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高影响因子
CHEMOSPHERE
·
2022
·
IF 8.943
Yunjin Zhong,Haixiang Chen,Xiufang Chen,Bingying Zhang,Wenxing Chen,Wangyang Lu
As some of the most promising alternatives to traditional non-degradable materials, photodegradable materials have advantages of environmental benignity and rapid degradation under simple conditions. In this work, nontoxic TiO 2 and cost-effective g-C 3 N 4 have been compounded in a weight of 9:1 to form a photocatalytic additive with high activity. A 25 wt% loading of this photocatalytic additive has been incorporated into the polyacrylonitrile (PAN) by centrifugal electrospinning to prepare an abiotic degradable PAN material. Our results showed that the PAN chain could be almost fully degraded within 90 h in an aqueous medium under simulated sunlight in the absence of microorganisms . Product analysis implied that degradation of the PAN chain mainly involved the breaking of –CN and C–C bonds by radicals, followed by oxidation of terminal groups to carboxyl and gradual mineralization to CO 2 and H 2 O. This design strategy may provide new insight for the production and degradation mechanism of photodegradable polymer.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
·
IF 7.312
Xueming Dang,Shuai Wu,Haiguang Zhang,Xie Quan,Huimin Zhao
A phosphorus (P) doped g-C 3 N 4 needle (PCNN) electrode with great photoelectrochemical (PEC) property is fabricated by a facile solid thermal melting approach. The proposed thermal melting method owns the advantages of low-cost, simple and easy operation, as only the solid mixing of melamine (C and N precursor) and triphenylphosphine oxide (P precursor) is needed in electrode preparation procedure. This method is further conducive to the formation of uniform film with doped heteroatom and unique microstructure on fluorine-doped tin oxide- coated glass (FTO). The PCNN photoelectrode holds a tip structure, which highly inhibits the recombination of photo-generated electron and hole. Particularly, the doped P in PCNN can further accelerate the photo-generated carrier separation and enhance the optical absorption property. As a result, the PCNN photoelectrode displays a five-fold enhancement of photocurrent density over pristine g-C 3 N 4 , reaching up to 127.4 µA cm - 2 at 1.23 V versus reversible hydrogen electrode (RHE), as well as good optical, chemical and physical stability. The PCNN photoelectrode further exhibits great property in PEC removal of pollutant in water. This study provides an effective fabrication method and opens new avenues for the significant improvement of g-C 3 N 4 based electrode in their various energy conversion and environmental application.
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NEW JOURNAL OF CHEMISTRY
·
2017
·Vol. 42
·期 1
·489-496
·
IF 3.269
Zengyu You,Qianhong Shen,Yuxuan Su,Yang Yu,Hui Wang,Tian Qin,Fang Zhang,Di Cheng,Hui Yang
A novel Z-scheme core–shell g-C3N4/MCNTs/BiOI heterojunction was successfully designed and fabricated through filling multi-walled carbon nanotubes (MCNTs) with g-C3N4, followed by the loading of BiOI on the outer surface of the MCNTs. The structure–property relationship was analyzed by X-ray diffraction (XRD), Fourier transform infrared spectra (FT-IR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), UV-vis diffuse reflectance spectra (DRS), photoluminescence spectra (PL), ESR probe tests and reactive species trapping measurements. The results show that the BiOI nanoparticles are uniformly loaded on the surface of the MCNTs which are fully filled by g-C3N4. The MCNTs connect the two semiconductors of g-C3N4 and BiOI, and serve as electron mediating conductors to promote the transfer of the photo-generated electrons, thereby constructing a Z-scheme heterojunction between g-C3N4 and BiOI. With this unique structure, enhanced visible-light photocatalytic activities are achieved because of the synergistic effect of light harvesting and improved separation efficiency of photo-generated carriers.
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Nanomaterials
·
2019
·Vol. 10
·期 1
·1
·
IF 4.034
Rui Geng,Juanjuan Yin,Jingxin Zhou,Tifeng Jiao,Yao Feng,Lexin Zhang,Yan Chen,Zhenhua Bai,Qiuming Peng
The construction of heterojunctions provides a promising strategy to improve photocatalytic hydrogen evolution. However, how to fabricate a nanoscale TiO2/g-C3N4heterostructure and hinder the aggregation of bulk g-C3N4using simple methods remains a challenge. In this work, we use a simple in situ construction method to design a heterojunction model based on molecular self-assembly, which uses a small molecule matrix for self-integration, including coordination donors (AgNO3), inorganic titanium source (Ti(SO4)2) and g-C3N4precursor (melamine). The self-assembled porous g-C3N4nanotube can hamper carrier aggregation and it provides numerous catalytic active sites, mainly via the coordination of Ag+ions. Meanwhile, the TiO2NPs are easily mineralized on the nanotube template in dispersive distribution to form a heterostructure via an N–Ti bond of protonation, which contributes to shortening the interfacial carrier transport, resulting in enhanced electron-hole pairs separation. Originating from all of the above synergistic effects, the obtained Ag/TiO2/g-C3N4heterogenous photocatalysts exhibit an enhanced H2evolution rate with excellent sustainability 20.6-fold-over pure g-C3N4. Our report provides a feasible and simple strategy to fabricate a nanoscale heterojunction incorporating g-C3N4, and has great potential in environmental protection and water splitting.Keywords:heterojunction;Ag/TiO2/g-C3N4;Co-assembly;hydrogen evolution
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高影响因子
OPTICAL MATERIALS
·
2022
·
IF 3.754
Zhengdong Zhang,Xingyu Chen,Shanhua Chen,Qi Dong,Xinyi Zhang,Ao Jiang,Dafu Zhang,Yuli Di,Taishan Li
A Z-scheme TiO 2 /g-C 3 N 4 heterostructure system was used to activate peroxymonosulfate (PMS) for the photocatalytic degradation of Rhodamine B (RhB). The Z-scheme TiO 2 /g-C 3 N 4 heterojunction photocatalysts were successfully synthesized by using a simple impregnation method. The structure and surface morphology of the samples were characterized by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), X-Ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The optical and electrochemical properties were characterized by UV–vis diffuse reflectance spectroscopy (DRS), photoluminescence (PL) electrochemical impedance spectroscopy (EIS).The results indicated that the Z-scheme heterojunction between TiO 2 and g-C 3 N 4 was successful established and the optimal photocatalytic activity was achieved when the mass ratio of TiO 2 to g-C 3 N 4 is 10:1. The degradation rate of RhB (20 mg/L, 50 mL) was 82.79% within 120 min simulated sunlight irradiation. After adding PMS to 10% TiO 2 /g-C 3 N 4 heterojunction photocatalysts , the reaction rate constant (k) of the TiO 2 /g-C 3 N 4 -PMS system is about 11.39 times as large as that with 10% TiO 2 /g-C 3 N 4 system. Moreover, the free radical trapping experiments results demonstrated that h + and SO 4 − · were the main active species in the TiO 2 /g-C 3 N 4 -PMS system.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2020
·
IF 3.99
Hanjun Wu,Weijun Zhang,Huali Zhang,Yi Pan,Xiaofang Yang,Zhiquan Pan,Xuejun Yu,Dongsheng Wang
In this work, the novel graphitic carbon nitride (g-C 3 N 4 ) and porous polyimide (PI) supported calcined hydrotalcite-like compounds (g-C 3 N 4 @PI@CHTLcs) were synthesized by co-precipitation and hydrothermal synthesis method, and systematically characterized by physical and chemical methods . The composites showed layered structure and a high thermal stability, and performed well in adsorption of tetracycline (TL), 2, 4-dichlorophenol (DP) and glyphosate (GH). The action pH value was ranged from 7 to 9 for TL and GH, and 3–9 for DP, respectively. The adsorption of TL and DP by g-C 3 N 4 @PI@CHTLcs conforms to the pseudo-first-order kinetic model . While for GH, the kinetic data fit well with pseudo-second-order model, indicating chemical adsorption via electrostatic interaction mechanism. Freundlich isothermal could better describe the adsorption process of TL, DP and GH. The maximum adsorption amounts of TL, DP and GH based on Langmuir isotherm model at 298 K were 231.1, 185.05 and 177.34 mg g −1 , respectively. The adsorption processes of TL, DP and GH were all endothermic and spontaneous, and showed excellent repeatability and stability in regeneration experiments. Additionally, the presence of chloride ion and humic acid (HA) showed no obvious effects on the adsorption process of organic contaminants. The diffusion mechanism of TL, DP and GH on the adsorption process was liquid membrane control. The adsorption mechanism might be the ion exchange between the layers of hydrotalcite, and the surface complexation and hydrogen bonding between various groups of PI and organic contaminants. The research showed that g-C 3 N 4 @PI@CHTLcs was effective in treatment of water containing various organic pollutants .
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Journal of Environmental Chemical Engineering
·
2025
·Vol. 14
·期 1
·120879
·
IF 7.2
Chengzhao Liu,Tao Liu,Suhua Liu,Xiufang Zhang,Guanlong Wang
Recently, it was reported photocatalytic H 2 O 2 generation performed in biphasic system could significantly increase the H 2 O 2 yield. Aiming to further improve the H 2 O 2 yield, hydrophobic heterojunction of α-S and vacancy-rich g-C 3 N 4 (CNN) was constructed. H 2 O 2 production performance tests demonstrated the 0.2α-S/CNN composite achieved H 2 O 2 yields 1.72 and 1.99 times higher than pristine CNN and α-S, respectively. N-(C) 3 bonded nitrogen(N 3 C ) promoted oxygen activation, and heterojunction facilitated the separation of photogenerated holes and electrons. These contributed more effective photocatalytic synthesis of H 2 O 2 . The optimal 0.2α-S/CNN achieved a production rate of 2218 μmol g −1 , with an impressive apparent quantum yield (AQE) of 6.92 % under 455 nm monochromatic light, outperforming the state-of-the-art catalysts. The proposed mechanism suggested that photogenerated electrons migrated from α-S to CNN, reducing adsorbed O 2 to form •O 2 − radicals. These radicals subsequently reacted with water in the aqueous phase to generate H 2 O 2 via 2e − ORR. Due to the strong hydrophobicity of the catalyst, most •O 2 − radicals were generated in benzyl alcohol (BA) phase, while H 2 O 2 predominantly formed in the aqueous phase. This spatial separation delayed H 2 O 2 decomposition, facilitating its accumulation and enhancing overall yield.
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高影响因子
Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Yuanliang Gu,Zinan Zhang,Shengshen Gu,Qi Zhang,Meng Guo,Yang Pan,Genghao Gong,Zhaoliang Cui,Xiuxiu Ren,Jing Zhong
1,2-bis(triethoxysilyl)ethane (BTESE)-derived organosilica membranes have good acid-resistant stability in the application of acetic acid dehydration via pervaporation technology. To enhance the separation performance of water (0.26 nm) and acetic acid (0.43 nm), graphitic carbon nitride (g-C 3 N 4 ) distinguished by its periodic nanoporosity (0.31-0.34 nm) and hydrophilic functionality, offers exceptional potential for organosilica-based membranes improvement. Herein, we tailored g-C 3 N 4 nanostructures as 2D nanosheets (4 nm thickness) and 0D quantum dots (4 nm diameter), and embedded them into BTESE membranes. For their thermal stability, the nanosheets enhanced structural integrity due to interlayer covalent/hydrogen bonding networks, while quantum dots exhibited a larger weight loss but preserved more residues at 800 o C. Nanosheets incorporated BTESE/g-C 3 N 4 composites reduced BTESE pore size, amplified surface hydrophilicity and membrane thickness, whereas quantum dots with abundant functional groups minimally altered BTESE matrix structures. In pervaporation of acetic acid/water, BTESE performance was improved by both morphologies of g-C 3 N 4 fillers at the same optimal loading. The nanosheet-incorporated membrane (BTESE/CN-NSs-3) achieved a separation factor of 2327 with a flux of 2.35 kg/m 2 ·h, while quantum dots-incorporated membrane (BTESE/CN-QDs-3) exhibited a higher flux of 2.52 kg/m 2 ·h but a lower separation factor of 1352. In feed concentration (50–90 wt% AcOH) and temperature dependent (55–95 °C) operations, nanosheets facilitated molecule sieving through interlayer channels, whereas quantum dots enabled lower-resistance pathways by diffusivity dominated permeation. This work establishes g-C 3 N 4 dimensionality modulating organosilica membrane’s transport hierarchy, providing a selection for developing acid-resistant membranes in improving flux and separation factor.
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Journal of Materials Chemistry C
·
2025
·
IF 5.1
Rui Ding,Wenjuan Zhang,Shiva Pandeya,Xueqing Zhu,Kai Xu,Meixing Gui,Hongbing Wang,Ziliang Li,Qianqian Shang,Mahesh Kumar Joshi
The design of a double Z-type heterojunction represents a promising strategy in photocatalysis to achieve superior charge carrier separation, increased light-harvesting capability, and consequently, a higher photocatalytic reaction rate. Herein, a novel ternary heterojunction with direct dual Z-scheme configuration, g-C3N4/In2S3/In2O3 photocatalyst, was synthesized using a chemical bath and facile calcination process. The XRD, SEM-EDS and XPS results confirmed the successful integration of g-C3N4, In2S3, and In2O3 with preserved crystalline phases. Photocatalytic performances of the ternary composite were evaluated via two effective routes, such as methyl orange (MO) degradation and hydrogen (H2) generation, benchmarked against the pristine g-C3N4 and the g-C3N4/In2S3 and In2S3/In2O3 binary composite, revealing that the in-situ growth of In2O3 onto the g-C3N4/In2S3 composite contributed to the remarkable enhancement of their photocatalytic activity. The photodegradation process follows the pseudo-first order reaction kinetics. The ternary g-C3N4/In2O3/In2S3 heterojunction exhibited 94.8% degradation efficiency of MO with a corresponding rate of 23.4×10-3 min-1, 4.8 times higher than the pristine g-C3N4, and excellent photocatalytic activity in five consecutive cycles. Similarly, the g-C3N4/In2S3/In2O3 heterojunction exhibited a rate constant of ~2.4 mmol h−1 g−1 for H2 generation. This superior enhancement was attributed to the dual Z-scheme charge transfer mechanism. The formation of direct dual Z-scheme heterojunction improved the light harvesting, minimized electron hole recombination, and efficiently facilitated the separation of charge carriers. This work provided a mechanistic insight for engineering multifunctional heterojunction for environmental remediation and pollutant mitigation.
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高影响因子
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
·
2024
·
IF 6
Yuxin Feng,Xuan Xuan,Yuemiao Hu,Jiaguo Lu,Zhiwen Dong,Ziqiang Sun,Hongying Yao,Lei Hu,Qikun Yin,Yi Liu,Hongbo Wang
Murine double minute 2 (MDM2) and homologous protein murine double minute X (MDMX) are p53 negative regulators that perform significant driving effects in tumorigenesis, and targeting these oncoproteins has became an efficient strategy in treating cancers. However, the definite antitumor activity and significance ordering of each protein in MDM family is still unclear due to the similar structure and complicated regulation. Herein, we identified two G-rich sequences ( G 1 and G 5 ) located in the promoter that could assemble the G-quadruplex to respectively inhibit and promote the transcription of the MDM2 and MDMX. Based on this target, we designed and synthesized a novel G-quadruplex ligand A3f and achieved the differentiated regulation of MDM protein. In triple-negative breast cancer (TNBC) cells, A3f could induce MDM2-dependent proliferation arrest and exhibit additive therapeutic effect with MDMX inhibitors. Overall, this study provided a novel strategy to regulate the transcription of MDM genes by targeting certain G-rich sequences, and discovered an active antitumor molecule for use in TNBC treatment.
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高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2019
·
IF 7.65
Ming Wu,Xin He,Binghua Jing,Teng Wang,Chengyin Wang,Yanlin Qin,Zhimin Ao,Shaobin Wang,Taicheng An
Graphite carbon nitride ( g -C 3 N 4 , CN) is considered as a promising semiconductor for environmental catalysis. However, pure CN can not meet the requirements for actual applications due to its high recombination rate of photogenerated electron-hole pairs and a relatively large band gap preventing full utilization of solar energy. In this work, we report synthesis of a novel carbon and defects co-modified g -C 3 N 4 (C x CN) by calcination of melamine activated by oxalic. This new catalyst C x CN has porous structure with much higher surface areas compared with pristine CN. UV–vis analysis and DFT calculations show that C x CN has a lower bandgap for enhancing visible light adsorption compared with CN. Photoluminescence (PL) and photoelectrochemical analyses show that C x CN has a low recombination rate of photogenerated electron-hole pairs, which improves the utilization of solar energy. As a result, C x CN samples show high efficiency for the degradation of bisphenol A (BPA) under visible light irradiation, where the best catalyst of C x CN (C 1.0 CN) samples shows about 22 times higher photocatalytic degradation rate than that of CN. Moreover, C 1.0 CN shows high mineralization rate and can degrade BPA into CO 2 and H 2 O by the generated active species, like superoxide radicals ( O 2 − ) and holes (h + ).
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