SENSORS AND ACTUATORS B-CHEMICAL
·
2023
·
IF 8.4
Niu Wu,Di Wu,Yueyi Shen,Li-e Liu,Lihua Ding,Yongjun Wu,Ningge Jian
Thiophenols are widely used in chemical and pharmaceutical industries , but the acute toxicity and irritating effects of these chemicals pose a threat to public health. A nanofibrous membrane-based fluorescent and colorimetric sensor was synthesized for the convenient and portable detection of thiophenols relying on the nucleophilic substitution reaction of chlorinated dipyrrole fluoride (BODIPY). To improve the sensing efficiency, β-CD was introduced as an addictive to regulate the molecular structure and physicochemical properties of the substrate membrane. The result showed that β-CD with appropriate cavity had good capability for complexing with the probe BODIPY, which successfully reduced the leakage of BODIPY during used. Also, thiophenol could be enriched by β-CD, and enhanced ratiometric fluorescence responses were achieved. The improved hydrophilicity facilitated the full contact of the NFM with thiophenol, contributing to a fast and efficient sensing process.The sensor system achieves a much shorter response time (180 s) and an extremely lower detection limit (0.11 nM). Furthermore, the sensor's fluorescent color changes can be identified by naked eye, showing great promise for the real-time on-site monitoring of thiophenols in both water and gas phases. Possible sensing mechanisms were investigated through theoretical calculation. Practical feasibility was validated through the actual sample analysis.
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CHEMOSPHERE
·
2023
·
IF 8.8
Yong Zhang,Siqi Huang,Bingyu Mei,Xiaoyu Tian,Lingyi Jia,Nan Sun
As a novel adsorbent for the separation of uranium(VI) from wastewater, Magnetite/β-cyclodextrin/fly ash composite (Fe 3 O 4 /β-CD/FA) was first prepared via a chemical coprecipitation technology . The characterization results indicated that Fe 3 O 4 and β-CD had been successfully loaded on FA, which had brought abundant oxygen-containing functional groups, providing numerous adsorptive sites for the removal of uranium(VI). At pH = 5.0 and T = 25 °C, the maximum uranium(VI) removal efficiency and capacity of Fe 3 O 4 /β-CD/FA were higher to 97.8% and 444.4 mg g −1 , respectively. Pseudo-second-order and Langmuir models fitted better with the experimental data, illustrating that chemical adsorption dominated the uranium(VI) removal process. In addition, Fe 3 O 4 /β-CD/FA showed good anti-interference ability and recoverability . After five cycles, the removal rate of uranium(VI) on Fe 3 O 4 /β-CD/FA was still higher to 90.4%. The immobilization of uranium(VI) on Fe 3 O 4 /β-CD/FA was mainly ascribed to the synergism of redox reaction, complex reaction, chemical reaction and electrostatic interaction. Given the above, Fe 3 O 4 /β-CD/FA would be regarded as an efficacious, green and promising adsorbent for uranium(VI) separation from wastewater.
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DESALINATION
·
2023
·
IF 9.9
Yuchen Du,Biplob Kumar Pramanik,Yang Zhang,Veeriah Jegatheesan
β-cyclodextrin (β-CD) and tannic acid (TA) together as an organic phase and zeolitic imidazolate framework-8 (ZIF-8) as an additive can be used along with trimesoyl chloride (TMC) as a monomer to synthesize nanofiltration (NF) membranes. Those membranes have better separation performance and provide higher flux. In this study, a new NF membrane was synthesized using them to investigate the effects of monomer concentration, substrate morphology, and reaction temperature on membrane performance . The results showed that when the concentrations of both β-CD and TA were 1 wt%, the membranes had the highest selectivity (2.99) for monovalent and divalent salts. A 10-fold increase in TMC concentration (0.05 to 0.5 wt%) optimized membrane selectivity and flux. When both spongy and cavernous structures were present in the substrate, the membranes could achieve >85 % removal of monovalent and divalent salts. After the introduction of ZIF-8, the roughness of the membrane increased, and the removal rate of monovalent salts decreased significantly, resulting in a salt selectivity of 7.97 and a flux up to 27.81 ± 1.17 L/(m 2 h). The growth of ZIF-8 on the membrane surface was assisted by an increase in the reaction temperature.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Liqin Zhou,Qiuyuan Huang,Hongbing Ji,Xuan Tang,Yuxuan Zhang,Kungang Chai
Bisphenol A (BPA) is a common industrial products ingredient, whose widespread utilization leads to a non-negligible problem of water pollution. For efficient adsorption of BPA, hyper-crosslinked β-cyclodextrin polyurethane (CDPU-HCP) was synthesized via crosslinking β-cyclodextrin (β-CD) with 4,4′-diphenylmethane diisocyanate followed by further external crosslinking reaction. CDPU-HCP showed high surface area (1133.12 m 2 ∙g −1 ) and has hierarchically pores, such as β-CD nanocavities, micropore and mesopores. Adsorption data fitted better with Freundlich adsorption isotherm model and the pseudo second order kinetic model. The fitted maximum adsorption capacity toward BPA was shown to be 371.8 mg∙g −1 . The stable adsorption performance during successive six recycling experiments indicated the excellent recyclability of CDPU-HCP. Furthermore, the density functional theory (DFT) calculations showed hydrophobic interaction of β-CD cavity and π-π interactions between aromatic moieties and BPA synergistically promoted the adsorption process. Therefore, CDPU-HCP was suggested to be a promising adsorbent in the treatment of BPA.
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MOLECULES
·
2023
·Vol. 28
·期 12
·4604
·
IF 4.6
Li Zhang,Mengting Zhang,Pingping Yang,Yin Zhang,Junjie Fei,Yixi Xie
Rutin, as a biological flavonoid glycoside, has very important medicinal value. The accurate and rapid detection of rutin is of great significance. Herein, an ultrasensitive electrochemical rutin sensor based on β-cyclodextrin metal–organic framework/reduced graphene oxide (β-CD-Ni-MOF-74/rGO) was constructed. The obtained β-CD-Ni-MOF-74 was characterized by X-ray diffraction spectroscopy (XRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), and nitrogen adsorption and desorption. The β-CD-Ni-MOF-74/rGO presented good electrochemical properties benefiting from the large specific surface area and good adsorption enrichment effect of β-CD-Ni-MOF-74 and the good conductivity of rGO. Under optimal conditions for the detection of rutin, the β-CD-Ni-MOF-74/rGO/GCE showed a wider linear range (0.06–1.0 μM) and lower detection limit (LOD, 0.68 nM, (S/N = 3)). Furthermore, the sensor shows good accuracy and stability for the detection of rutin in actual samples.Keywords:electroanalysis;carbon materials;electrochemical reduction;modified electrode
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高影响因子
APPLIED SURFACE SCIENCE
·
2023
·
IF 6.7
Dongli Li,Liqin Zhou,Zongwu Wei,Xingzhen Qin,Hongbing Ji,Kungang Chai
Chlorophenols (CPs), a kind of important intermediate for fine chemicals, exists widely in the aqueous environment and poses a significant danger to humans. Therefore, developing advanced materials to enable the effective capture of CPs is highly desired. Herein, β-cyclodextrin-based porous carbon (CPAC) with exceptional capacities for CPs has been designed and tested. These porous carbon adsorbents were successfully synthesized via stepwise carbonization, affording abundant N and O functional groups, high surface area (as high as 3982 m 2 ·g −1 ) and controlled pore size to optimize for rapid CPs uptake. According to the CPs uptake measurements, CPAC exhibited exceptional CPs adsorption performance. CPAC showed high adsorption capacities (1085.08 mg · g −1 for 2,4,6-trichlorophenol) and fast adsorption kinetics for CPs. CPAC can effectively recover multi-component CPs from complex aqueous media, and the special pore structure reduces the competitive adsorption between CPs. And the recyclability studies showed that CPAC maintained its structural integrity and the initial CPs uptake capacity, highlighting its potential for practical application. Besides, DFT calculations indicate that hydrogen bonding and π-π interactions are key factors. Among them, the molecular conformation of CPs and the number of chlorine atoms on phenol play a crucial role in the adsorption behavior and adsorption energy.
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ACS Applied Nano Materials
·
2023
·
IF 5.9
Fangling Li,Dongdong Cao,Wenyi Gu,Lin Cui,Zhongpeng Qiu,Zhiyong Liu,Dongmei Li,Xuhong Guo
Kaposi’s sarcoma-associated herpesvirus (KSHV) infection can cause a range of malignancies. The use of microRNA (miRNA) to combat viruses and inhibit tumor development has received increasing attention. However, it is difficult for free miRNA to enter into cells directly and to degrade easily. Therefore, the miRNA therapy alone often fails to achieve the expected effect. The selection of an appropriate delivery system for effective miRNA delivery and anti-KSHV is rarely considered. In this study, a β-cyclodextrin-grafted polyethylenimine (β-CD-PEI) was prepared by the chemical synthesis method, and folic acid was further coupled to a nanocarrier (β-CD-PEI-FA). Gel electrophoresis retardation experiments showed that β-CD-PEI-FA could combine with miR-34a-5p to form a drug-carrying nanocomplex β-CD-PEI-FA/miR-34a-5p, which effectively protected miR-34a-5p from serum and nuclease degradation. The particle size and potential were 203.13 ± 0.41 nm and 27.02 ± 0.72 mV, respectively, which were suitable for endocytosis. The cytotoxicity of the vector to KSHV-positive cells BCBL-1 and SK-RG cells was detected by the CCK-8 assay, which proved that the vector had good biosafety in vitro. Further cell experiments showed that β-CD-PEI-FA/miR-34a-5p not only had the ability to transport miR-34a-5p but also accelerated the G2-phase process of BCBL-1 and SK-RG cells and inhibited the proliferation of KSHV-infected cells. Most importantly, it can significantly reduce the expression levels of KSHV genes ORF26, K8.1A, and LANA. Therefore, the nanocarriers may be a promising antiviral drug delivery system with potential applications in the anti-KSHV therapy.
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RSC Advances
·
2023
·Vol. 13
·期 19
·12863-12868
·
IF 3.9
Feng Gao,Xinmin Zhao,Qiankang Si,Xingkun Niu,Shaojie Hou,Shihao Liu,Jun Guo,Liping Wang,Feng Zhang
Peptide-based scaffolds have been widely applied to drug delivery because of their ease and high yields of synthesis, well-defined structure, biocompatibility, diversity, tunability of properties, and molecular recognition abilities. However, the stability of peptide-based nanostructures highly depends on the intermolecular assembling manner, e.g., α-helix based coiled coils, β-sheet. Inspired by the robust protein fibril structures in amyloidosis, herein we constructed a β-sheet-forming gemini surfactant-like peptide to self-assemble into nanocages with the help of molecular dynamics simulation. As expected, the experimental results showed that nanocages can be formed with the inner diameter of up to ∼400 nm, which were robust enough even under both transmission electron microscopy and atomic force microscopy, indicating the significant contribution of β-sheet conformation. The β-nanocages can load hydrophobic anticancer drugs, e.g., paclitaxel with a very high encapsulation efficiency, which holds great potential for clinic drug delivery due to the improved anticancer effect as compared with paclitaxel alone.
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BIOMEDICINE & PHARMACOTHERAPY
·
2023
·
IF 7.5
Baiyi Yan,Yanchun Gong,Wei Meng,Huizhen Sun,Wenxi Li,Kaizhi Ding,Caixia Dang,Xiaofei Gao,Wei Sun,Chunhua Yuan,Songhua Wang,Li-Hua Yao
Type 2 diabetes mellitus (T2DM) is a common and multiple endocrine metabolic disease. When pancreatic β cell in case of dysfunction, the synthesis and secretion of insulin are reduced. This study is to explore the effect of cordycepin (the molecular formula C 10 H 13 N 5 O 3 ), a natural adenosine isolated from Cordyceps militaris , on high glucose/lipid-induced glucotoxicity and lipotoxicity in INS-1 cells. Our results showed that cordycepin improved cell viability, improved cell energy metabolism and promoted insulin synthesis and secretion. The mechanism may be related to that cordycepin reduces intracellular reactive oxygen species (ROS), increases ATP content in cells, causes membrane depolarization and balances the steady state of Ca 2+ concentration, cordycepin inhibits cell apoptosis, which may be related to the downregulation of proteins level of c-Jun N-terminal kinases (JNK) phosphorylation, cytochrome c (Cyt-c), Cleaved Capase-3, the mRNA level of JNK, Cyt-c, Capase-3 and upregulation of proteins/mRNA level of pancreatic and duodenal homeobox factor-1 (PDX-1). These results suggest that cordycepin can inhibit cell apoptosis and protect cell number by downregulating ROS/JNK mitochondrial apoptosis pathway under high glucose/lipid environment, thereby improving the function of pancreatic islet cells, providing a theoretical basis for the related research on the prevention and control of cordycepin on T2DM.
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高影响因子
FASEB JOURNAL
·
2023
·Vol. 37
·期 5
·e22924
·
IF 4.8
Liangjie Lu,Huihan Wang,Minjie Yang,Lijun Wang,Kaifeng Gan
Beta-tricalcium phosphate (β-TCP) is considered as one of the most promising biomaterials for bone reconstruction. This study generated a functional molybdenum disulfide (MoS 2 )/polydopamine (PDA)/−bone morphogenetic protein 2 (BMP2)-insulin-like growth factor-1 (IGF-1) coating on the β-TCP scaffold and analyzed the outcomes. The MoS 2 /PDA-BMP2-IGF-1@β-TCP (MPBI@β-TCP) scaffold was prepared by 3D printing and physical adsorption, followed by characterization to validate its successful construction. The in vitro osteogenic effect of the MPBI@β-TCP scaffold was evaluated. It was found that MPBI@β-TCP augmented the adhesion, diffusion and proliferation of mesenchymal stem cells (MSCs). The alkaline phosphatase (ALP) activity, collagen secretion and extracellular matrix (ECM) mineralization along with the expression of Runx2, ALP and OCN were also enhanced in the presence of MPBI@β-TCP. Additionally, MPBI@β-TCP stimulated endothelial cells to secrete VEGF and promoted capillary-like tubule formation. We then confirmed the biocompatibility of MPBI@β-TCP to macrophages and its anti-inflammatory effects. Furthermore, under near-infrared (NIR) laser irradiation, MPBI@β-TCP produced photothermal effect to not only kill MG-63 osteosarcoma cells, but also enhance bone regeneration in vivo with biosafety. Overall, this work demonstrates that 3D-printed MPBI@β-TCP with enhanced osteogenic activity under NIR laser irradiation has a vast potential in the field of tissue defects.
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高影响因子
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
·
2023
·Vol. 98
·期 7
·1620-1630
·
IF 3.4
Minhua Zhang,Yan Zhang,Yuxin Tan,Guochao Yang,Haoxi Jiang,Lingtao Wang
BACKGROUND With the improvements in bioethanol production, the process of converting ethanol to 1,3-butadiene (ETB) has received substantial scholarly attention, whose industrialization has been constrained by the stability of the catalysts. RESULTS In this work, the deactivation behavior of Zr- β zeolite in the process of ethanol/acetaldehyde conversion to 1,3-butadiene was investigated. In addition, the deactivation kinetics of ETB was studied using an isothermal differential microreactor. A kinetic model was developed and parametrized with the Langmuir–Hinshelwood mechanism, and the intrinsic kinetic equation was derived. The deactivation kinetic model of the ETB reaction was established from the active site content of the catalyst as a function of time on stream. The validity of the kinetic model was tested, and the results were found to be accurate. CONCLUSIONS Catalyst deactivation was mainly caused by coke species, which are mainly long-chain unsaturated oxygenated organic compounds and aromatic compounds, covering Lewis acid sites in the microporous channels of the catalyst; nevertheless the zeotype topology and morphology were not destroyed. The kinetic data suggested that the reaction was of first order and the activation energy of the deactivation process was 75.59 kJ mol −1 . © 2023 Society of Chemical Industry (SCI).
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ACS Omega
·
2023
·
IF 4.1
Baikang Zhu,Qinbin Dong,Jianghua Huang,Mengmeng Yang,Xianlei Chen,Chunyang Zhai,Qingguo Chen,Bohong Wang,Hengcong Tao,Li Chen
Fabrication of S-scheme heterojunctions with enhanced redox capability offers an effective approach to address environmental remediation. In this study, high-performance Bi2Sn2O7/β-Bi2O3 S-scheme heterojunction photocatalysts were fabricated via the in situ growth of Bi2Sn2O7 on β-Bi2O3 microspheres. The optimized Bi2Sn2O7/β-Bi2O3 (BSO/BO-0.4) degradation efficiency for tetracycline hydrochloride was 95.5%, which was 2.68-fold higher than that of β-Bi2O3. This improvement originated from higher photoelectron–hole pair separation efficiency, more exposed active sites, excellent redox capacity, and efficient generation of ·O2– and ·OH. Additionally, Bi2Sn2O7/β-Bi2O3 exhibited good stability against photocatalytic degradation, and the degradation efficiency remained >89.7% after five cycles. The photocatalytic mechanism of Bi2Sn2O7/β-Bi2O3 S-scheme heterojunctions was elucidated. In this study, we design and fabricate high-performance heterojunction photocatalysts for environmental remediation using S-scheme photocatalysts.
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