CHEMICAL ENGINEERING JOURNAL
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2026
·
IF 12.5
Asim Mushtaq,Khai Ly Do,Muhammad Yousaf,Saiquan Li,Miao Su
Thermo-adaptive injectable silk-hydrogel conforms dynamically to irregular wound beds. • Au-TiO 2 /ICG nano-assemblies for image-guided localization • NIR-triggered hyperthermia/ROS generation synergistic antibacterial treatment • IVIS-guided tracking of the hydrogel's delivery and retention • Multifunctional platform helps improve wound repair with excellent biocompatibility. Infection and chronicity of wounds pose an intimidating problem in clinical practice, necessitating a system that would be able to dynamically adjust to the changes in the wound bed, delivering antibacterial effects and monitoring them simultaneously. Herein, a thermo-adaptive injectable hydrogel using Au–TiO 2 –PF127–ICG (ATI) nanocomposites loaded in a silk hydrolysate-PEG 400 -gelatin (SPG) matrix has been developed, integrating mechanical adaptability, phototherapy, biocompatibility, and imaging functionality in a single construct. The hydrogel is stable at room temperature while undergoing gel-sol phase transition at physiological temperature, thus allowing simple injection and in situ shaping within irregular wounds. Rheological analysis confirmed a distinct gel–sol transition near physiological temperature, validating its thermo-adaptive nature. Upon NIR 808 irradiation, the incorporated indocyanine green (ICG) efficiently converted light into heat, while the Au–TiO 2 nanocomposites along the ICG produced reactive oxygen species (ROS), resulting in a dual photothermal/photodynamic antibacterial effect against E. coli and S. aureus . Infrared thermal imaging and IVIS fluorescence visualization further confirmed localized photothermal responsiveness and sustained hydrogel retention at the wound site, enabling fluorescence-assisted image-guided localization and monitoring. Furthermore, in vivo studies revealed accelerated wound closure, enhanced collagen deposition, and favorable histological regeneration under NIR stimulation, signifying the hydrogel's regenerative potential. Overall, this ATI-SPG hydrogel demonstrates a harmonious combination of injectability, self-adaptivity, fluorescence-enabled image-guided localization, NIR-triggered multimodal antibacterial therapy, and wound healing capability, providing a promising platform for next-generation light-responsive materials for wound management.
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ENVIRONMENTAL RESEARCH
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2026
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IF 8.2
Youzhou He,Zhiqiang Guo,Yue Li,Xingyan Liu,Kaili Wu,Yuyu Fang,Rong Peng,Min Fu,Bowen Lei
The elimination of low-concentration (ppb) nitrogen oxides (NO x ) in city and indoor environments, particularly the selective removal of NO while preventing toxic NO 2 formation is a significant challenge. Photocatalytic technology offers a promising solution, but its effectiveness is limited by high carrier recombination rates and insufficient active sites. This study introduces a photocatalyst (Au@NM/ZIF) that forms a Z-type heterojunction structure by precisely positioning gold nanoparticles within the NM/ZIF framework. The catalyst consists of amino-functionalized NH 2 -MIL-125 and ZIF-8, with gold nanoparticles serving dual roles: UV-Vis analysis shows that their surface plasmon resonance (SPR) enhances visible light absorption, promoting the generation of charge carriers that drive the oxidation of NO to NO 3 − . Additionally, X-ray photoelectron spectroscopy (XPS) and work function analysis indicate that gold nanoparticles function as an electronic bridge, optimizing charge transfer between NM and ZIF-8, improving electron-hole separation and increasing active site utilization, thereby significantly enhancing NO conversion efficiency. In situ Fourier-transform infrared spectroscopy (FT-IR), electron spin resonance (ESR), and radical capture experiments further clarify the formation pathways of preliminary products and completed outputs, emphasizing the important roles of active radicals (such as •OH and •O 2 − ) in the deep oxidation of NO. This research offers a valuable solution for effectively removing low-concentration NO x .
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高影响因子
APPLIED ORGANOMETALLIC CHEMISTRY
·
2026
·Vol. 40
·期 5
·e70579
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IF 4.3
Changqing Xia,Zhengshen Bao,Dehong Xu,Shixing Wang,Weili Li
A robust metal–organic framework (MOF) material, UIO67-PS, was synthesized by grafting sulfonic acid groups onto the UIO67-NH 2 framework. This modification significantly enhances the electronegativity and coordination-site density on the MOF surface, enabling threefold higher Au (III) adsorption capacity (536.4 mg/g at pH 2.0 temperature 25°C and agitation speed 120 rpm) compared to pristine UIO67-NH 2 (168.4 mg/g). The material exhibits exceptional acid resistance and recyclability (91% capacity retention after three cycles). Density functional theory (DFT) calculations and X-ray photoelectron spectroscopy (XPS) analyses reveal that the adsorption mechanism is governed by synergistic electrostatic interactions and chelation, wherein electron-rich oxygen/nitrogen-containing functional groups on the adsorbent surface coordinate with metal ions via covalent bonds to form stable five-membered ring complexes. Kinetic studies confirm rapid adsorption equilibrium (< 240 min), while thermodynamic analysis indicates an endothermic, entropy-driven process. Notably, UIO67-PS demonstrates superior selectivity for Au (III) over competing ions (e.g., Zn 2+ and Cu 2+ ) in simulated e-waste leachates. Achieving removal rates as high as 80% in real metallurgical wastewater highlights its potential for practical application. This work reveals key coordination interactions, including complexation and electrostatic attraction, within a simulated e-waste leachate system containing competing ions such as copper and nickel. These insights advance the design strategies of MOFs for sustainable Au (III) recovery and provide a scalable platform for industrial wastewater treatment, contributing to environmental protection and the sustainable utilization of critical material resources.
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ANALYTICAL CHEMISTRY
·
2026
·
IF 7.3
Xiaoxuan Ren,Hui Geng,Yue Sun,Shengjie Li,Guizheng Zou
Nanoparticles (NPs) are alternative chemiluminescence (CL) luminophores to molecular luminophores and are strongly anticipated to extend molecular luminophore-tagged commercial CL immunoassays (CLIA) with wavebands beyond the eye-visible region and sensitivity beyond the pg/mL level. Herein, a surficial bond-involved repetitive excitation strategy for near-infrared CL with enhanced photons per luminophore is proposed by exploiting l-methionine (l-Met)-capped gold NPs (AuNPs) as luminophores. The surficial Au–S bonds of l-Met@AuNPs can be involved in the procedure of NP core excitation via oxidation, and bring out defect-involved CL around 830 nm. Because there are plenty of Au–S bonds on every AuNP core, l-Met@AuNPs can be repetitively excited over a hundred times and give off greatly enhanced CL photons per luminophore than all molecular CL luminophores. CL of l-Met@AuNPs/(NH4)2S2O8 can directly enable automatic near-infrared CLIA for myoglobin (MYO) determination on in vitro diagnostic instruments, with a limit of detection of 10 fg/mL (S/N = 3), which significantly surpasses the threshold of molecular luminophores. This Au–S bond-triggered AuNP CL strategy not only offers an alternative to molecular CL strategies with improved sensitivity and to II–VI NP CL strategies with fewer toxic concerns, but also indicates that exploiting the surficial bond energy of NPs could be an alternative to designing NPs with unique morphology, structure, and composition in the CL domain.
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高影响因子
OPTICAL MATERIALS
·
2026
·
IF 4.3
Shuai Yang,Jialin Wang,Han Bao,Weili Liu,Jinshu Li,Jiao Xu,Hongwei Liang,Yiming Yang
Self-powered perovskite photodetectors (PDs) have emerged as an attractive platform for energy-efficient and low-power optoelectronic applications. However, achieving superior self-powered photodetection performance with wide linear dynamic range (LDR) and high-temperature stability remains challenging, due to the formidable defect-assisted ion migration and thermally activated carrier injection. Here, we demonstrate a thermally robust self-powered PD incorporated with a high-quality chemical vapor deposition grown CsPbBr 3 nanoplate and engineered Schottky contacts. The asymmetric Ti and Au contacts establish an effective built-in electric field that enables self-powered operation, and the adequate Schottky barrier efficiently suppresses thermally activated dark current. Meanwhile, the high crystalline quality of CsPbBr 3 nanoplates, characterized by a low defect density, minimizes trap-assisted carrier transport or ion migration, which contributes to the reduction of dark current and enhancement of photodetection robustness at elevated temperatures. As a result, the device exhibits impressive self-powered photodetection figures of merit with an ultralow dark current (∼-0.25 pA), a wide LDR of 137 dB, and a reliable operation up to 450 K. Notably, the responsivity is further enhanced at elevated temperatures. This work provides a clear physical strategy for realizing outstanding self-powered perovskite PDs with high-temperature robustness.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2026
·
IF 8.3
Runzi Zhang,Xiaoyu Yang,Shunbi Xie,Bo Wu,Yao Liu,Yi He
Herein, target-induced catalytic hairpin assembly (CHA) integrate with a pH-responsive DNA triple helix structure is first used to construct a recyclable layered covalent organic framework ( L -COF) @Au as a SERS substrate for the ultrasensitive detection of ofloxacin (OFL). Firstly, a large specific surface area and abundant -NH 2 groups of the L -COF serves as an ideal carrier for Au NPs, enabling the generation of a strong and uniform electromagnetic field. Meanwhile, target-triggered catalytic hairpin assembly (CHA) is utilized to activate an efficient DNA walker system, thereby achieving significant amplification of the SERS signal. Notably, pH-responsive folding and unfolding of the DNA triplex can enables capture and release of the SERS tag (Au@4-NTP@Ag) to achieve regeneration of the SERS substrate, thus allowing multiple reuse cycles. Furthermore, a synergistic plasmonic enhancement effect was realized between the COF@Au substrate and the SERS tag, resulting in a broad dynamic detection range from 1.0 × 10 −13 mol/L to 1.0 × 10 −6 mol/L and a low limit of detection (LOD) of 5.79 × 10 −14 mol/L. The biosensor demonstrates accurate quantification in real food samples, confirming its practical applicability. In addition, the methodology simplifies experimental procedures and reduces operational costs. Overall, this study presents a highly selective and responsive sensing approach for constructing renewable SERS-based biosensors, providing a robust and prospective platform for the monitoring of antibiotics in food safety applications.
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高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2026
·
IF 9.6
Ruofei Li,Hao Zhou,Jing Yao,Tiefeng Xu,Gangqiang Wang,Wangyang Lu
The conversion of 5-hydroxymethylfurfural (HMF) to 2,5-furandicarboxylic acid (FDCA) via aerobic oxidation is a crucial step toward transforming biomass into sustainable bio-based energy materials. In this study, a mesoporous Au-CoO x /m-CeO 2 catalyst was prepared using vacuum-assisted in situ self-assembly to realise this conversion. The well-defined mesostructure, as confirmed by transmission electron microscopy and nitrogen adsorption–desorption analyses, significantly enhanced active site accessibility and facilitated reactant diffusion, thereby accelerating the selective oxidation of HMF to produce FDCA. This catalytic system achieved complete conversion of HMF and an FDCA yield of 99.89 ( ± 0.03)% under ambient pressure at 90 °C. Using Au/m-CeO 2 or Au-CoO x /CeO 2 as catalysts under identical conditions, the FDCA yields were limited to 56.8 ( ± 1.9)% and 78.1 ( ± 0.8)%, respectively. The optimal catalyst also demonstrated outstanding durability, retaining 93.9 ( ± 0.7)% FDCA yield after 18 reuse cycles. This remarkable activity was attributed to the integrated Au-CoO x /m-CeO 2 architecture, wherein a synergistic metal–oxide interaction coupled with the ordered mesoporous CeO 2 framework collectively optimised the reaction–diffusion process, driving efficient HMF oxidation. This study therefore provides a new perspective for designing efficient catalysts for the conversion of HMF to FDCA, which is conducive to the conversion of biomass resources.
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高影响因子
IEEE SENSORS JOURNAL
·
2026
·
IF 4.5
Zhaocheng Shao,Yupeng Zhao,Jianyuan Huang,Haozhan Sun,Shuhua Wei,Jing Zhang,Anjie Ming
Unpredictable variation of surface-enhanced Raman scattering (SERS) intensity, caused by uncontrolled interfacial adsorption, severely limits quantitative applications. To address this issue, the evolution of analyte adsorption states was systematically investigated on a 3D Au nanoparticles/ZnO nanoflowers (Au NPs/ZnO NFs) substrate. By correlating Raman signal fluctuations with finite element method (FEM) simulations, a four-stage interfacial adsorption model consisting of direct adsorption, indirect adsorption, saturation, and crystallization was established). Spatial volume integral evaluations reveal that during initial adsorption, capillary forces drive molecules to form an optimal monolayer within extreme nanogaps, thereby maximizing the utilization of hot spots and triggering a rapid signal surge. Conversely, excessive volume induces thick crystallization, leading to severe optical shielding and a global collapse of the localized electric field. Guided by this framework, the optimal linear dynamic range was defined, overcoming false-negative interference. Furthermore, the substrate achieved a 10-8 M limit of detection for Rhodamine 6G (R6G) and exceptional 15-minute photocatalytic self-cleaning. This study presents a high-performance, reusable SERS platform and establishes a universal physical framework that maps macroscopic sample volume to microscale adsorption dynamics, providing crucial guidelines for maximizing linearity and defining accurate dynamic ranges in practical SERS detection protocols.
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高影响因子
ANALYTICA CHIMICA ACTA
·
2026
·
IF 6.1
Jialiang Wu,Junyi Hu,Jingchang Tian,Xinyi Li,Nan Wang,Yinghua Yan,Fangying Shi,Chuan-Fan Ding
Au/TOHFHs enable reproducible LDI-MS metabolic fingerprinting of cattle. • Serum metabolic signatures reveal zoonotic infection-associated changes. • Machine learning accurately classifies BTB and BRU from healthy cattle. • The strategy supports livestock surveillance and food safety monitoring. Rapid analytical methods capable of discriminating livestock diseases are highly desirable for early animal health surveillance and food-chain risk control. Herein, a gold nanoparticle-modified ternary metal oxide hierarchical flower-like heterostructures (Au/TOHFHs) was developed as a high-performance matrix for laser desorption/ionization mass spectrometry (LDI-MS)-based metabolic fingerprinting. The hierarchical architecture and plasmon-enhanced interface synergistically improved metabolite enrichment, energy utilization, and ion efficiency. Using standard metabolite solutions, the Au/TOHFHs matrix exhibited good analytical reproducibility, with coefficients of variation of 5.24−14.95% for intra-spot replicate measurements and 6.71−14.90% for inter-spot spatial sampling. Using 178 bovine serum samples, including 96 samples from cattle with bovine tuberculosis, 31 from cattle with brucellosis, and 51 healthy controls, the platform accurately distinguished bovine tuberculosis and brucellosis from healthy cattle, achieving receiver operating characteristic curve areas under the curve of 0.983 and 0.899, respectively, in independent validation. Furthermore, simplified nine-metabolite and seven-metabolite biomarker panels for bovine tuberculosis and brucellosis, respectively, retained robust predictive performance, with independent-validation areas under the curve of 0.983 and 0.958, respectively, while reducing model complexity. This strategy enables rapid, label-free, and high-throughput livestock screening from minimal serum volumes, providing a practical tool for large-scale herd surveillance and strengthening food safety management through source-level risk control. Download: Download high-res image (295KB) Download: Download full-size image
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ANALYTICA CHIMICA ACTA
·
2026
·
IF 6.1
Xin Zhuang,Jing Lin,Jialun Lin,Ranxi Mo,Xinyan Zheng,Yiqing Chen,Yuhua Hu,Ruiyun You,Yudong Lu
Functionalized Au@Ag NRs were immobilized in a triple-network hydrogel for wearable SERS sweat sensing. • Three reporter-functionalized hydrogel channels enabled ratiometric SERS detection of azelaic acid, H 2 O 2 , and pH. • The ATPPZn hydrogel showed good signal uniformity, reproducibility, 100-day storage stability, and skin-contact adaptability. • Sensitive detection of azelaic acid and H 2 O 2 was achieved with detection limits of 7.8 × 10 −13 M and 66.1 μM, respectively. • Real sweat analysis confirmed the feasibility of the platform for monitoring skin-inflammation-related molecular changes. Skin inflammation is commonly accompanied by oxidative stress and changes in the local acid–base microenvironment, whereas molecular indicators reflecting inflammation-associated metabolic changes remain less explored in wearable sensing. Azelaic acid, a dicarboxylic acid associated with inflammatory skin conditions, represents a potential small-molecule target, yet its non-invasive analysis in sweat remains challenging. Herein, a wearable-compatible ratiometric surface-enhanced Raman scattering (SERS) platform was constructed by embedding functionalized Au@Ag nanorods into a TEMPO-oxidized cellulose nanofibers (TOCNF)/poly(vinyl alcohol) (PVA)/poly(acrylamide-co-acrylic acid) [P(AM-co-AA)]-Zn 2+ triple-network hydrogel. The hydrogel architecture promoted nanoprobe dispersion and immobilization while maintaining flexibility and signal stability, yielding a spatial SERS relative standard deviation (RSD) of 5.19% and 77% signal retention after 100 days. Using Au@4-ATP@Ag nanorods (NRs) containing 4-ATP as a Raman-responsive reporter, azelaic acid was quantified through the ratiometric I 1194 /I 1073 response over 1 × 10 −12 –1 × 10 −7 M, with a detection limit of 7.8 × 10 −13 M, and its analytical feasibility in sweat was further evaluated by spike-recovery analysis. To provide complementary information on inflammation-related microenvironmental changes, the same hydrogel architecture was further adapted for H 2 O 2 and pH sensing using Au@4-MPBA@Ag and Au@4-MBA@Ag NRs, respectively. The H 2 O 2 channel exhibited a concentration-dependent response over 1-500 μM, while the pH response agreed well with pH-meter measurements, with deviations within 0.07 pH units. These results demonstrate the analytical feasibility of azelaic acid as an underexplored inflammation-related sweat target and highlight the potential of the triple-network SERS hydrogel for integrating molecular and microenvironmental information in skin-related sweat analysis. Download: Download high-res image (313KB) Download: Download full-size image
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Jiaojiao Su,Yaning Zhang,Mingli Yue,Jian Liu
Cell chirality is a complex phenomenon that imparts unique properties. The creation of biomimetic artificial cells chirality is a rapidly evolving research topic that has had a profound impact in multiple fields, including materials science, catalysis, biotechnology, and biomedicine. Herein, we report a simple method that combines L- or D-penicillamine (L/D-Pen) with proteinosomes on the surface of gold nanoparticles to afford nanoparticle hybrid microcapsules. Encapsulation of the enzyme in the microcapsule enables a chiral recognition effect on the membrane surface, thereby affording control over the enantioselective catalytic reaction of the d -glucose (D-Glu) substrate loaded inside the hybrid microcapsule. The adsorption energy of D-Glu and D-Pen (−0.095) calculated by MS is less than that of D-Glu and L-Pen (−0.064). Thus enantiomeric selective recognition is a stronger interaction force than adsorption for the same configuration. These findings highlight the development of biomimetic chiral microcompartments, and provide a platform for driving cellular chirality in various organisms.
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高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2025
·
IF 4.6
Yiyao Luo,Huan Liu,Xuhui Xia,Huizhen Fu,Mingyi Guo,Changjun Hou,Danqun Huo
Baijiu plays an essential role in Chinese food culture, but there are still certain limitations in the identification of the aroma type and brand of Baijiu. In this study, based on the Tollen’s reagent, a colorimetric sensor array was constructed for aldehydes and Baijiu discrimination. In the presence of aldehydes or Baijiu, the silver ions (Ag + ) adsorbed by negatively charged nanoparticles can be reduced to elemental silver (Ag 0 ) in situ. Ag 0 deposited on the surface of gold or silver nanopaticle (Au NPs or Ag NPs) leading to the formation of Au@Ag or Ag@Ag core-shell structure which accompanied by a color change. We developed Tollen’s reagent-based sensor array shows the outstanding detection capability in discriminating and quantifying of aldehydes. On this basis, 16 kinds of Baijiu were also identified accurately, the visual results were verified by HCA and LDA models. The colorimetric sensor developed in this study is promising for aroma recognition and brand identification of Baijiu.
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高影响因子
危险品化学品经营许可证（带存储）