JOURNAL OF ALLOYS AND COMPOUNDS
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2024
·
IF 5.8
Peng Yu,Juan Tan,Ronghao Zhuang,Jing Tang,Zhiguo Wang,Chun Zhang,Qiongchao Wang,Xinxin Xiao,Wei Huang
Reutilizing heavy metal enriched adsorbents into efficient photocatalysts for antibiotic removal is of great economic value. Herein, spent alkali-lignin biochar (ALB) with enriched Zn 2+ /Cd 2+ ions is valorized into ZnS-CdS/C photocatalyst via a simple vulcanization method. ZnS-CdS/C (3:1) exhibits a superior photocatalytic removal efficiency of 98.6 % for levofloxacin (LEV), with about 60 % of the initial value remained after four cycles. It also shows good photocatalytic removal efficiencies of 92.1 %, 95.4 % and 84.0 % for enrofloxacin, ciprofloxacin and tetracycline, respectively. Electron paramagnetic resonance (ESR) shows that the introduction of ZnS and CdS in ALB promotes the generation of oxygen vacancies and persistent free radicals (PFRs). The photocatalytic LEV removal mechanism of ZnS-CdS/C indicates that both the abundant PFRs and photogenerated electrons serve as electron donors, efficiently reducing dioxygen to superoxide free radicals (·O 2 - ). The ·O 2 - formed in the above two ways continuously degrade the LEV molecules. Finally, the biotoxicity and developmental toxicity of LEV degradation intermediates confirms that the ZnS-CdS/C degradation system can remove LEV effectively with reduced harm to the ecological environment.
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高影响因子
FUEL
·
2024
·
IF 6.7
Xi Li,Haiyong Wang,Kingdom Alorku,Jin Wang,Longlong Ma,Ying Xu
Efficient hydrogenolysis of C-O bonds in lignin offers a promising pathway for producing high-value-added biofuels and chemicals. However, designing an easily synthesized, highly active catalyst for this process remains a challenge. In this paper, a series of Ni-M(Pd, Pt, Ru)/C catalysts were prepared and synergized with NaOH to produce aromatic compounds from β-O-4 model compound (MC). Among the catalyst systems, Ni-0.25 % Pd/C-NaOH completely converted β-O-4 MC at mild conditions (150 °C, 2 MPa H 2 , 3 h) to produce monomers with a yield of 95.6 wt% and excellent selectivity of the bond-breaking products as high as 85.5 %. Recycling tests showed that the Ni-0.25 % Pd/C catalyst remained stable after five cycles, with high activity and without the need for a further reduction before runs. Further, the catalytic system has proven to exhibit high activity for the cleavage of other types of lignin MC, such as 4-O-5, α-O-4, β-O-4 and ether bond (diphenyl ether, benzyl phenyl ether, Guaiacolylglycerol-β-guaiacol ether, benzyl ether) and also effective for lignin from enzymatic cleavage (LEC). Hydrogenolysis of LEC achieved a monomer yield of 34.5 wt%; the molecular weight (555 g/mol) of the hydrogenolysis oligomer was significantly reduced compared to LEC (2872 g/mol). The highly active and stable Ni-0.25 % Pd/C-NaOH catalytic system provides a promising pathway for the efficient hydrogenolysis of lignin and lignin model compounds to produce high-value biofuels and chemicals.
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MICROCHEMICAL JOURNAL
·
2024
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IF 4.9
Xinmei Qian,Chunxiang Li,Mingyu Zheng,Jinglun Wang,Haowen Huang,Keqin Deng
In this work, a regenerable magnetic omeprazole electrochemical sensor was developed for the first time. Firstly, a magnetic bamboo-like nitrogen-carbon (N-C) nanotubes encapsulated with iron-nickel alloy (FeNi) nanoparticles (FeNi@N-CNTs) was prepared by a pyrolysis route. The characterization techniques including high resolution transmission electron microscopy (HRTEM), scanning electron microscope (SEM), X-ray diffraction (XRD), energy disperse spectroscopy (EDS), and X-ray photoelectron spectroscopy (XPS) revealed the surface morphology, structure, and chemical composition of the FeNi@N-CNTs. Cyclic voltammograms (CVs) and electrochemical impedance spectroscopy (EIS) results indicated that FeNi@N-CNTs had excellent conductivity and greatly facilitated the electron transfer. By applying FeNi@N-CNTs, a designed magnetic base support, and screen-printed electrode (SPE), a regenerable magnetic SPE was developed. The presence of FeNi@N-CNTs caused better omeprazole electron transfer kinetics at SPE surface. The FeNi@N-CNTs/SPE showed a linear detection range of 0.05–25.0 μM with a detection limit of 14 nM (S/N = 3) for detecting omeprazole. Due to the FeNi@N-CNTs adhering to SPE surface by magnetic control and easy disengagement from the electrode surface by magnetism, the proposed sensor was simple, regenerable, and cost-effective.
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高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2025
·Vol. 36
·期 2
·1-13
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IF 2.8
Feng Hao,Li Xiaohua,Gao Shilun,Guo Ruijie,Wei Yuchen,Yang Dandan,Yang Huabin
With low redox potential, natural abundance and cost-effective of sodium resources, sodium-ion batteries (SIBs) are considered as a promising alternative for the currently dominant energy storage devices, i.e., lithium-ion batteries. However, developing suitable anode materials is still a challenge for the practical applications of SIBs. Alloy anodes have high specific capacity and low operating voltage, but the inherent volume expansion results in rapid capacity decay and poor cycling stability. Herein, focus on this issue, a novel carbon-coated alloy composite (SbSn@C) was synthesized by the solid-phase reduction of chloride method. Surface morphology analysis confirms that the SbSn@C composite exhibits a porous structure with a carbon layer of 20–30 nm, which can accommodate volume expansion. Furthermore, the synthesized SbSn@C composite exhibits impressive electrochemical performance with a good reversible capacity (450.5 mAh g −1 after 100 cycles, 90% capacity retention). As expected, such synthesis strategy provides a basis for the development of cost-effective and environmentally friendly sodium-ion batteries.
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高影响因子
International Journal of Applied Ceramic Technology
·
2025
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IF 2.3
Yulong Wang,Zhoufu Wang,Xitang Wang,Hao Liu,Yan Ma,Yunjie Dong,Shenghao Zeng
Short carbon fibers were treated with an ultrasonic-enhanced liquid-phase oxidation method and introduced into Al 2 O 3 -C refractories. The effects of different liquid-phase preoxidized carbon fibers on the mechanical properties and thermal shock resistance of the refractories were compared and investigated. The results indicate that ultrasonic-enhanced liquid-phase preoxidation can effectively modify the surface of carbon fibers, thereby affecting the structural evolution and usage effect of carbon fibers in Al 2 O 3 -C refractories. Appropriate liquid-phase preoxidation treatment for carbon fibers can enhance their strengthening effect on the mechanical properties of Al 2 O 3 -C refractories. After the addition of carbon fibers treated with liquid-phase preoxidation for 20 min, compared to the refractories without carbon fibers, the cold modulus of rupture, cold crushing strength, and hot modulus of rupture of Al 2 O 3 -C refractories (after 1300°C heat treatment) increased by 15.4%, 10.3%, and 36.7%, respectively. Furthermore, the introduction of liquid-phase preoxidized carbon fibers can have a positive effect on the thermal shock resistance and toughness ratio of Al 2 O 3 -C refractories.
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高影响因子
AQUACULTURE
·
2024
·
IF 3.9
Jingya Li,Mingyang Xue,Chen Xu,Nan Jiang,Yiqun Li,Yuding Fan,Yong Zhou,Yan Meng
Largemouth bass ranavirus (LMBRaV) is a highly lethal virus that has devastated the largemouth bass aquaculture sector. Therefore, it is imperative to develop therapeutic strategies for the control of this pathogen. In this work, the antiviral activity of Saikosaponin C was examined both in vitro and in vivo . According to the results of the in vitro antiviral activity assay, 30 mg/L of Saikosaponin C significantly down-regulated the expression of the LMBRaV major coat protein (MCP) gene in epithelioma papilloma cyprinid (EPC) cells, with an inhibitory rate exceeding 84%, and prevented LMBRaV replication in a dose-dependent manner. It also significantly limited its cytopathic effect (CPE), thereby playing a protective role on infected cells. Notably, Saikosaponin C has a certain preventative impact on the virus by influencing the mechanisms by which viral particles connect to cell receptors, which prevents LMBRaV from adsorbing on EPC cells. Simultaneously, Saikosaponin C also directly inactivated LMBRaV. The results of exploring the viral invasion cycle demonstrated that Saikosaponin C primarily exerted its antiviral effect during the middle stage (2–6 h) of viral infection. In addition, Saikosaponin C inhibited LMBRaV-induced apoptosis of EPC cells, maintained physiological cellular morphology and structure, and protected cells from loss of cellular morphology, formation of apoptotic vesicles, and cell fragmentation. Moreover, Saikosaponin C considerably improved the survival of virus-infected largemouth bass, according to the findings of in vivo investigations. In summary, Saikosaponin C demonstrated excellent anti-LMBRaV activity and holds considerable promise for development in the field of aquaculture.
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Reaction Chemistry & Engineering
·
2025
·
IF 3.1
Weidong Liu,Jianguo Liu
Reusable catalysts based on non-noble metals with broad applicability for nitrile catalytic hydrogenation are key to achieving more sustainable primary amine production. Herein, a simple and efficient carbon-coated non-noble nickel-based catalyst (Ni/NiO@C-600-200-1-H₂O) was developed for the hydrogenation of aromatic substituted nitriles to aromatic substituted amines under relatively mild conditions (120 °C, 10 bar H₂, 4 h). The carbon-coated structure endows the catalyst with excellent anti-agglomeration properties, significantly enhancing its cyclic stability. The catalyst exhibits high tolerance toward various functional groups, including halogen, methyl, and methoxy, achieving remarkable conversion rates (over 99%) and product selectivity (up to 98.25%). Additionally, the catalyst's magnetic properties facilitate easy recovery and reuse. When applied to a continuous flow reactor for benzonitrile hydrogenation under optimized conditions, the catalyst demonstrated a conversion rate and selectivity exceeding 99%, with continuous operation lasting up to 31 h.
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Journal of Advanced Research
·
2025
·
IF 13
Yajing Li,Runping Liu,Jianan Li,Feng Gao,Zhi Ma,Kaihong Xie,Fanghong Li,Bing Xu,Qi Zheng,Yajie Cai,Jiaorong Qu,Xiaoyong Xue,Kexin Jia,Xiaojiaoyang Li
Introduction Cholestatic liver diseases are highly prevalent and lack effective treatment, ultimately progressing to end-stage liver diseases. Our recent study indicates that the interplay between c-MYC and lncRNA H19 exacerbates the ductular reaction during cholestasis. Objective: This study aims to unveil the underlying mechanisms of the protective effects of senkyunolide A (SenA) on cholangiocyte overproliferation in cholestatic liver diseases. Methods : Through comprehensive characterization using RNA sequencing, CHIP analysis, protein truncation, amino acid mutation or deletion, and the development of SenA derivatives, we explored the effects and mechanisms of SenA in vivo in bile duct ligation mice and in vitro in primary cholangiocytes. Results : We demonstrated that SenA effectively mitigates cholangiocyte hyperproliferation by epigenetically suppressing c-MYC expression and disrupting the downstream H19, Let-7a and Lin28a. Mechanically, we identified a potential interaction between the carbonyl group in SenA and Arg483 in TRAF6, disrupting the TRAF6-HDAC3 complex. This dissociation facilitates the binding of HDAC3 to the MYC promoter region, resulting in enhanced histone deacetylation and transcriptional suppression. Conclusion : We highlight the therapeutic potential of SenA in cholestatic liver diseases by elucidating its role in epigenetic regulation.
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PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Chen-Xuan Li,Wenhui Xu,Bai Li,Xiangyang Xu,Xian-Zhong Fu,Rui Deng,Feng Zhang,Yimin Sun,Kangping Cui
Waste cartons produced by e-commerce and the express delivery industry pose urgent environmental and social challenges, making their recycling a critical issue in recent years. In this study, a novel strategy for upcycling waste cartons into a Fenton-like chainmail catalyst, CoO x @C-P-8 (CoO x confined carbonaceous matrix), through a one-step pyrolysis process using waste cartons adsorbed cobalt nitrate was proposed. The catalytic activity of CoO x @C-P-8 in activating peroxymonosulfate (PMS) for the removal of tetracycline hydrochloride (TCH) was thoroughly evaluated. The results indicated that the combination CoO x @C-P-8 (0.3 g/L) and PMS (1.0 mM) could remove 92 % of TCH within 60 min. Mechanistic studies revealed that both singlet oxygen ( 1 O 2 ) and radicals (i.e. SO 4 •− , O 2 •− and HO • ) contributed to TCH removal, with cobalt-loading, N-doping, and the defective graphitic structure identified as the key governing factors. The unique chainmail structure of CoO x @C-P-8 endowed it with pronounced resistance to interference from ions (Cl − , NO 3 − , HCO 3 − , H 2 PO 4 − , K + , Mg 2+ , and Na + ) and pH variations (pH 3.0–11.0). Furthermore, the high environmental viability of CoO x @C-P-8, evidenced by ease of magnetic separation and simple catalyst regeneration, was demonstrated. This work may offer a feasible strategy for upcycling waste cartons and also contribute substantively to the advancement of wastewater decontamination.
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高影响因子
International Journal of Nanomedicine
·
2025
·
IF 6.5
Zhuhui Feng,Jing Lin,Qian Wang,Lina Zhang,Lingwen Gu,Bing Yu,Xueyun Fu,Daohao Li,Guiqiu Zhao,Cui Li
Purpose To investigate the therapeutic potential of sulfur vacancy-molybdenum disulfide/carbon composite nanosheets (MoS2-x/C NS) in Aspergillus fumigatus (A. fumigatus) keratitis in mice.Methods The in vitro antifungal efficacy of MoS2-x/C NS against A. fumigatus was evaluated by propidium iodide (PI) staining, minimum inhibitory concentration (MIC) determination, and biofilm formation assays. Toxicity assessments of the MoS2-x/C NS were conducted using a Lactate dehydrogenase (LDH) assay kit for in vitro cytotoxicity and the Draize eye test for in vivo ocular irritation. The severity of fungal keratitis in mice was assessed using clinical scoring, plate counting, and hematoxylin and eosin (H&E) staining. The anti-inflammatory efficacy of MoS2-x/C NS was determined by quantifying inflammatory factor levels using reverse transcription polymerase chain reaction (RT-PCR).Results In vitro, MoS2−x/C NS significantly inhibited A. fumigatus growth, demonstrated favorable biocompatibility, and reduced the expression of IL-6 and TNF-α in human corneal epithelial cells (HCECs) stimulated by inactivated A. fumigatus hyphae. In vivo, MoS2−x/C NS treatment significantly reduced fungal load, attenuated pathological corneal damage, and suppressed IL-6 and TNF-α levels, effectively alleviating A. fumigatus keratitis in mice.Conclusion This study demonstrates that MoS2-x/C NS possesses significant therapeutic potential for fungal keratitis mediated through dual antifungal and anti-inflammatory mechanisms, thereby improving the prognosis of A. fumigatus keratitis.
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PubMed
高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2025
·
IF 4.3
Jin Li,Yang Wang,Tianxing Wu,Xiujing Xing,Limin Li,Wei Xiong,Hao Li
Electrocatalytic reduction of nitrate for the synthesis of high-value chemical hydroxylamine (NH 2 OH) represents a sustainable pathway that combines the dual functions of green synthesis and wastewater treatment. However, the selective control of the process is extremely challenging, mainly due to the susceptibility of nitrate to over-reduction during the reaction, leading to uncontrolled conversion of the target product NH 2 OH to the thermodynamically stable product ammonia (NH 3 ). In this paper, the Cu-PDA MOF precursor was synthesized using the emulsion method, and ZIF-8 was introduced to form the structure of Cu-PDA@ZIF-8. Subsequently, the nitrogen-carbon-doped Cu-ZnO/N-C catalysts were formed by calcination under N 2 atmosphere. The synthesized catalyst effective improved NH 2 OH selectivity during nitrate reduction. The NH 2 OH yield and FE efficiency of Cu-ZnO/N-C reached 564.97 μmol h −1 mg cat −1 and 46.64 %, respectively, under neutral electrolyte conditions. Cu, as the main component of the catalyst, plays a dominant role in hydroxylamine by electrocatalytic nitrate reduction to promote the reaction in the stage of NO 3 – →*NH 2 OH. Zn, on the other hand, plays a key role in the phase *NH 2 OH → NH 2 OH, selectively generating the product NH 2 OH and blocking the excessive reduction of NH 2 OH to NH 3 . Additionally, this study achieved tandem catalytic selective generation of NH 2 OH at copper and zinc heterogeneous interfaces and offers a potential approach and reference for applications involving the nitrate reduction reaction.
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高影响因子
LIFE SCIENCES
·
2018
·
IF 3.234
Bo Shi,Shixing Li,Hao Ju,Xin Liu,Dan Li,Ying Li
The present study aimed to evaluate the renoprotective effects of chelerythrine (CHE), a protein kinase C inhibitor, on neonatal rats after partial unilateral ureteral obstruction (UUO) surgery. New born Sprague Dawley rats were subjected to partial UUO 48 h after birth and received a daily intraperitoneal injection of 5 mg/kg CHE. At 21-day age, the rats were scarified and the kidneys were collected for analysis. Results showed that CHE treatment significantly increased kidney weight and restored renal function in the obstructed kidney. Histological examination demonstrated that CHE attenuated renal injury by reducing renal parenchymal loss and preventing glomerular and tubular degeneration. In addition, CHE inhibited partial UUO-induced upregulated kidney injury molecule-1 expression and apoptosis and renal fibrosis. Moreover, as a PKC inhibitor, CHE significantly inhibited PKCα and PKCβ membrane translocation. This action may be associated with its effects of anti-apoptosis and anti-fibrosis and contribute to the renoprotection. This short-term study suggests that CHE is beneficial for obstructive nephropathy in neonatal rats and provides foundation for further studies to reveal the long-term effects of CHE on obstructive nephropathy in children and infants.
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高影响因子
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