FOOD CHEMISTRY
·
2020
·
IF 6.306
Ibrahim Abdelhai Senosy,Hao-Ming Guo,Mei-Nan Ouyang,Zhi-Heng Lu,Zhong-Hua Yang,Jian-Hong Li
In this work, zeolite imidazolate framework-8 (ZIF-8) functionalized magnetic graphene oxide (Fe 3 O 4 @APTES-GO/ZIF-8) was successfully synthesized and used as a novel adsorbent in magnetic solid-phase extraction (MSPE) for the determination of four triazole fungicides in water, honey and fruit juices. The main parameters such as extraction time, amount of adsorbent, the pH value of the sample, ionic strength, and desorption solvent which could affect the experiment results were optimization. Under the optimum condition, the obtained linearity of this method ranged from 1 to 1000 µg L −1 for all analytes, with correlation coefficients (R 2 ) ≥ 0.9914. Limit of detections (LODs) and limit of qualifications (LOQs) of four triazole fungicides were ranged from 0.014 to 0.109 µg L −1 and from 0.047 to 0.365 µg L −1 , respectively. Based on comparison with outcomes from other studies, Fe 3 O 4 @APTES-GO/ZIF-8-MSPE could provide high performance and achieve satisfied results for the analysis of trace triazole fungicides in complicated matrices.
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ANALYTICA CHIMICA ACTA
·
2020
·
IF 5.977
Shi-En Chen,Shuyun Zhu,Jingwen Hu,Jing Sun,Zhenjia Zheng,Xian-En Zhao,Huwei Liu
Glucosylsphingosine (GlcS) in plasma is considered to be a reliable biomarker of Gaucher disease . The detection difficulty of GlcS is that it is difficult to achieve simultaneous separation and quantification with its isomer galactosylsphingosine (GalS), a biomarker of Krabbe disease . In this work, a multiplexed stable isotope labeling absolute quantization strategy coupled with magnetic dispersive solid phase extraction using new prepared dummy magnetic molecularly imprinted polymers (DMMIPs) has been developed for this purpose by ultra high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS). 8-Plex Amine-reactive Mass Difference Tags (M360/361/362/363/373/375/376/378-AMDTs), were designed, synthesized and used to label GalS and GlcS in different 8 plasma samples, respectively. Synchronously, M359-AMDTs was prepared and used to label mixed standards of GalS and GlcS, which served as internal standards in UHPLC-MS/MS quantitation. Then DMMIPs possessing dual recognition function were applied for specific enrichment and purification of all GlcS and GalS derivatives from a combined solution of labeled 8-plex plasma samples and mixed standards before UHPLC-MS/MS injection. The labeling efficiency, chromatographic retention and mass spectrometry responses of all the 9 AMDTs reagents were consistent for GlcS and GalS. The established and validated method enabled 8-plex plasma samples quantification in a single UHPLC-MS/MS run (<2.0 min). Good linearity of AMDTs-GlcS/GalS derivatives was obtained in the range of 0.02–800 nM. LODs of GlcS and GalS were both 0.005 nM. The recoveries were in the range of 96.1–107.2%. The method was successfully applied for multiplex quantitative analysis of GlcS and GalS in human plasma samples. The results indicated that this method was capable of better realizing the simultaneous separation and quantification of GalS and GlcS compared to reported methods.
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MICROCHIMICA ACTA
·
2017
·Vol. 184
·期 10
·4091-4098
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IF 4.58
Liu Haochi,Chen Ligang,Ding Jie
The authors describe an efficient method for the extraction of tetracycline antibiotics (TCs) from water samples by using a new kind of core-shell adsorbent. It consists of a magnetite (Fe 3 O 4 ) core and a metal-organic framework (type ZIF-8) as the shell. The sorbent has a large specific surface and superparamagnetic response. The sorbent was characterized by transmission electron microscopy, X-ray photoelectron spectroscopy, nitrogen adsorption, and X-ray diffraction. The adsorption isotherms, dynamic adsorption, and mechanisms of interactions between tetracycline and sorbent were studied. Various parameters affecting the extraction efficiency were optimized. Following desorption of the TCs with methanol (containing 1% of acetic acid), they were quantified by using ultra-high performance liquid chromatography combined with mass spectrometry. The method has a linear range that extends from 0.5 to 50 ng·L −1 , and the limits of detection for tetracycline, chlortetracycline, and oxytetracycline are 0.125, 0.122 and 0.143 ng·L −1 , respectively. The relative standard deviations of intra-day and inter-day assays range from 3.3% to 8.5%, and from 2.8% to 8.3%, respectively. The recoveries of TCs (at spiking levels of 0.5, 5.0 and 50 ng·L −1 ) are in the range between 78.3% and 93.7%. The method was successfully applied to the determination of TCs in spiked river water, fish pond water, and livestock wastewater.
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JOURNAL OF CHROMATOGRAPHY A
·
2019
·
IF 3.858
Jijie Kong,Fengxi Zhu,Wen Huang,Huan He,Jiapeng Hu,Cheng Sun,Qiming Xian,Shaogui Yang
In this study, three kinds of Zeolite imidazolate framework-8 (ZIF-8), synthesized by solvothermal, stirring and ball-milling method, were fabricated on the stainless steel wire via sol-gel technique. These fibers were used as solid phase microextraction (SPME) coating materials and applied for analyzing 16 polycyclic aromatic hydrocarbons (PAHs) and 11 nitro polycyclic aromatic hydrocarbons (NPAHs) in environmental water samples by gas chromatography-tandem mass spectrometry (GC–MS). The optimal pH, ionic strength, extraction time, extraction temperature, desorption temperature and desorption time were 6.0, without salt addition, 45 min, 35 °C, 260 °C and 5 min, respectively. The extraction mechanism of the ZIF-8 fiber might be the hydrophobicity , molecular penetration and π-π stacking interactions. Under the optimized conditions, the as-proposed fiber provides a wide linearity range from 10 to 20,000 ng L −1 and a low detection limit of 0.3–27.0 ng L −1 for PAHs and NPAHs analysis. The single fiber and fiber to fiber relative standard deviations were observed in the range of 3.0%–13.9% and 3.5%–12.3%, respectively. The method shows great potential in environmental analysis field.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2025
·
IF 3.8
Wang Tingting,Li Dingxuan,Cheng Yuhuan,Zhang Yulian,Ye Jiannong,Chu Qingcui,Cheng Guifang
Homochiral zeolite imidazolate framework-8 (ZIF-8) combines the inherent characteristics of ZIF-8 with the chiral recognition function and open chiral channel, becoming one preferred choice for enantiomer separation. In this work, ZIF-8 with D-histidine as the chiral carbon center (D-His-ZIF-8) was introduced into the pores to enhance the extraction performance of hollow-fiber liquid-phase microextraction (HF-LPME). A novel method was developed for the selective and sensitive determination of chiral amino acids related to the nervous system by D-His-ZIF-8@HF-LPME coupled with capillary electrophoresis and laser-induced fluorescence detection. Under the optimal conditions, D-type amino acids could obtain higher enrichment efficiency than L-type ones due to the stronger geometry-dependent hydrogen-bonding interactions between L-type amino acids and the chiral channels of ZIF-8 materials modified with D-His, and the maximum enrichment factor reached 640 times (for D-serine). This developed method has been successfully applied to the analyses of four chiral amino acids (D/L-serine and D/L-aspartic acid) in exhaled breath condensate and saliva samples of healthy volunteers. The limits of detection were 0.030–0.30 nM (S/N = 3) in the real sample matrixes. This developed method meets the principles of green analytical chemistry and achieves a greenness score of 80 assessed by the analytical eco-scale tool. This proposed method provides one green alternative for the sensitive and accurate analyses of chiral amino acids in the non-invasive body fluids. Graphical abstract
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2025
·
IF 8.5
Jianing Zhang,Junjun Zhang,Lei Zhou,Nurmymeti Yasen,Abudulekemu Abudinaibi,Xiaowei Huang,Xiaodong Zhai,Zhihua Li,Jiyong Shi,Remah Sobhy,Ibrahim Khalifa,Xiaobo Zou
Intelligent films are essential for real-time monitoring of food spoilage. However, the application is often limited by challenges such as hydrophilicity and color instability. In this study, two high hydrophobic bilayer indicators based on sodium alginate-polyvinyl alcohol/chitosan-zein with alizarin grafted onto ZIF-8 carrier (AL@ZIF-8) were fabricated using the casting method and electrospinning, respectively. Molecular docking simulations confirmed the successful grafting of AL@ZIF-8 onto the film substrates. The performance of films was compared and the effectiveness in monitoring freshness indicators was evaluated. The cast film had a precisely controlled thickness due to self-assembly performance, resulting in superior mechanical properties (TS = 10.64 MPa, EB = 43.764 %). In comparison, the nanofiber films demonstrated higher UV-blocking ability (ΔE < 4), faster spoilage response, and greater safety (Cell viability >80 %). Importantly, the nanofiber films exhibited higher sensitivity in monitoring beef freshness, with a color change pattern strongly correlating with spoilage (R 2 = 0.8976).
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APPLIED CATALYSIS B-ENVIRONMENTAL
·
2024
·
IF 20.2
Yingdong Hao,Yonghui Zhao,Chunlai Zhang,Xinqing Chen,Nannan Sun,Wei Wei
Achieving a high yield of oxygenates and inhibiting overoxidation remain challenging for CH 4 photooxidation. Here, we report a catalyst with enriched Ag-ZnO interfaces by using ZIF-8 as the precursor. The resulting Ag/Z-450 photocatalysts show extraordinary efficiency in the photocatalytic oxidation of CH 4 , a high liquid oxygenate yield of 57.88 mmol·g cat −1 (28.94 mmol·g cat −1 ·h −1 ) and a selectivity of ∼100 % were obtained over 3.0Ag/Z-450, with HCHO as the major product (41.04 mmol·g cat −1 , ∼71 % selectivity). Mechanistic studies revealed that ZnO and Ag species acted as electron donors and acceptors, respectively, which enhanced charge carriers transfer and separation. CH 4 and O 2 can be effectively activated to generate •CH 3 and reactive oxygen species (ROS), their following reaction led to formation of CH 3 OOH, which can be further converted to CH 3 OH and HCHO. This work contributes to the development of a “two-in-one” CH 4 photooxidation catalyst system that simultaneously achieves unparallel productivity and selectivity.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Safdar Ali Amur,Quratulain Khuhro,Najaf Ali Soomro,Bharat Prasad Sharma,Ahmed Nadeem,Muhammad Tariq,Hao Liang
ZIF-8 has strong potential for biomedical applications due to its excellent biocompatibility. In this study, 89.67 % of natural drug magnolol (Mag) was loaded in ZIF-8 to form Mag@ZIF-8, which was subsequently modified with chitosan (CS) to obtain Mag@ZIF-8/CS. The prepared materials were characterized using the UV–Vis spectroscopy, FTIR, XRD, DLS, SEM and TEM techniques. Thermal stability of materials was analyzed using Thermos Gravimetric Analysis system. PDI and Z -average hydrodynamic sizes of Mag@ZIF-8/CS and Mag@ZIF-8 were increased compared to ZIF-8. Similarly, Mag@ZIF-8 revealed higher zeta potential (+17.5 ± 2.3 mV) than ZIF-8 (+9.8 ± 0.5 mV), but Mag@ZIF-8/CS exposed 3.2 ± 0.9 mV, in water; however, at pH 4 it was changed to +5 mV. Pure ZIF-8 and Mag@ZIF-8 exhibited a hexagonal morphology, while Mag@ZIF-8/CS had a rotund, flat-like structure, with mean particle size of 101 nm, 123 nm and 343 nm, respectively. Density Functional Theory (DFT) analysis offered a deeper insight into the electronic properties and binding interactions of the composites. Under acidic conditions, drug release from Mag@ZIF-8 was higher (86.4 %) and faster than from Mag@ZIF-8/CS (74 %), when tested at physiological pH 7.4 and 37 °C. This, suggests that CS modification of Mag@ZIF-8 is crucial for achieving prolonged and sustained drug release. Mag@ZIF-8 and Mag@ZIF-8/CS depicted a two-fold increase in antibacterial activity against E. coli and S. aureus , demonstrating a synergistic effect. The MIC value for E. coli and S. aureus were, 35 μg/mL and 20 μg/mL, respectively, confirming the enhanced antibacterial efficacy of the composites. Molecular docking analysis provided deeper insights into the binding interactions between the materials and the E. coli protein 5AZC.
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Sustainable Chemistry and Pharmacy
·
2024
·
IF 5.5
Xing Zhou,Ping-Yue Wang,Chen-Xi He,En-Jang Liu,Xiao-Hui Yao,Dong-Yang Zhang,Tao Chen
Recently, continuous-fluid catalysis technology has been widely used in biocatalysis. However, the poor stability of the reactor-supported enzyme and expensive manufacturing cost of the reactor restrict its use. Herein, a wood-based bioreactor, β-glucosidase@ zeolitic imidazolate framework-8@delignified wood (β-Glu@ZIF-8@DW), with attractive features was developed. The naturally oriented channels of the xylem-based reactor enable high throughput. The interference of the fluids through the porous inner walls in the directional channels of the xylem-based reactor considerably increased the probability of contact between the substrate and enzyme. Resveratrol with multifaceted biological activities exists in many plants, including Mulberry (Morus spp., Moraceae) and Camellia sinensis and Polygonum cuspidatum (P. cuspidatum) . However, it mainly presents in its glycosylated form (polydatin) rather than as free resveratrol in plant. To improve the acquisition of resveratrol, continuous convert polydatin into resveratrol by a bioreactor is a good strategy. The conversion rate of polydatin using the as-prepared reactor reached 98.98% in 2 h. The uniform distribution of β-Glu@ZIF-8 in the channel increased the stability of the bioreactor with an 80.28% conversion rate after seven cycles. The reactor provided an excellent strategy for continuous catalysis, which can be used for industrial production with low synthesis costs and high mass transfer efficiency. Therefore, it has great potential for commercial applications.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2023
·
IF 8.4
Wenhai Wang,Jiaxuan Li,Bin Hong,Yi Ma,Fei Chen,Keren Kang,Jufang Wang
High levels of Cu (II) in the human body can cause kidney dysfunction, liver cirrhosis, and many neurological diseases, such as Wilson’s disease (WD). Therefore, rapid and efficient detection of Cu (II) in urine is highly essential. First, by a simple multiple seeded growth method, the gold nanoclusters (Au NCs) embedded metal-organic framework (ZIF-8) is decorated on cellulose paper to generate a fluorescent Au NCs@ZIF-8 paper. Then the Au NCs@ZIF-8 paper is loaded on the fluidic cartridge integrated with the syringe for ultra-sensitive urine copper detection. The fluorescence paper is intercalated in a reusable fluidic cartridge and attached to a syringe, allowing the fluidic cartridge to flow a amount of samples through the paper. The interaction of Cu (II) with in situ growth of Au NCs@ZIF-8 on the paper induced fluorescence quenching , which fluorescence images can be recorded and analyzed by the portable smartphone-assisted device. Furthermore, a large amount of sample solution was flowed through the Au NCs@ZIF-8 paper, enabling more Cu (II) to react with the Au NCs@ZIF-8 paper on the novel paper-based analytical device (nPAD). Cu (II) detection can be completed by nPAD in 20 mins, and the limit of detection was as low as 9.2 nM. We show the value of the paper device for on-site detection of copper (II) and indicate that it has excellent potential for clinical applications and environmental monitoring.
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ANALYTICAL SCIENCES
·
2022
·Vol. 38
·期 10
·1305-1312
·
IF 1.967
Liu Piaotong,Hao Rusi,Sun Wenliang,Lin Ziyi,Jing Tianfeng,Yang Haizhen
A facile and efficient “bottle-around-ship” approach for preparing the ratiometric fluorescent probe has been developed by encapsulating the red-colored fluorescence CdTe quantum dots (QDs) and blue-colored fluorescence graphitic carbon nitride quantum dots (g-CNQDs) into the zeolitic imidazolate metal–organic frameworks (ZIF-8) in one step. At a single excitation of 360 nm, the obtained probe ZIF-8@g-CNQD/CdTe shows the dual-emission peaked at 450 and 633 nm, respectively. The red emission of CdTe QDs is selectively quenched by the Hg 2+ , whereas the blue fluorescence of g-CNQDs as an internal reference is insensitive, resulting in an apparent color transformation from pink to blue for special recognition of Hg 2+ . By this approach, the relative fluorescence intensity ratio ( F 633 / F 450 ) decreased linearly with increasing Hg 2+ concentration in the 0.2–3.5 μM range with a low limit of detection (LOD) of ~ 46 nM. Therefore, we demonstrate that this “bottle-around-ship” process provides a new strategy for the construction of ratiometric fluorescent Hg 2+ probes with good simplicity, high efficiency, and excellent stabilities. Moreover, the obtained Hg 2+ fluorescent probe shows good results in the detection of actual samples. Graphical abstract
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LWT-FOOD SCIENCE AND TECHNOLOGY
·
2022
·
IF 6.056
Chengtuo Niu,Lina Yang,Feiyun Zheng,Chunfeng Liu,Jinjing Wang,Xin Xu,Qi Li
This study aimed to provide a systematic analysis of the effect of environmental factors on the growth and volatile flavor compounds (VFCs) production ability of Zygosaccharomyces rouxii Y-8 and further elucidate its contribution to doubanjiang fermentation in different salinity. Lower salinity (0–9%), acidic pH (4.5–5.5), moderate temperature (25–35 °C) and air exposure favored the growth and VFCs accumulation of Z. rouxii Y-8, which also had higher concentrations of key jiang flavor contributing compounds benzene ethanol, 2-methoxy-phenol and pyrazines. Interestingly, samples with higher VFCs concentration were found to contain less kinds of VFCs. When inoculated into doubanjiang fermentation, Z. rouxii Y-8 showed critical roles on the formation of VFCs in doubanjiang . Among doubanjiang samples fermented in different salinity, doubanjiang with 9% salinity had the highest kinds of VFCs. Moreover, its flavor was more balanced and the jiang flavor was stronger. This indicated that the presence of adequate salinity was necessary for Z. rouxii Y-8 to produce critical VCFs responsible for doubanjiang flavor. The results would provide researchers and manufacturers with a deeper understanding of the characteristics of Z. rouxii Y-8 and rationales to utilize Z. rouxii Y-8 as starter to produce high quality BBFFs.
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危险品化学品经营许可证（带存储）