INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2025
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IF 8.5
Jiaojiao Su,Yaning Zhang,Mingli Yue,Jian Liu
Cell chirality is a complex phenomenon that imparts unique properties. The creation of biomimetic artificial cells chirality is a rapidly evolving research topic that has had a profound impact in multiple fields, including materials science, catalysis, biotechnology, and biomedicine. Herein, we report a simple method that combines L- or D-penicillamine (L/D-Pen) with proteinosomes on the surface of gold nanoparticles to afford nanoparticle hybrid microcapsules. Encapsulation of the enzyme in the microcapsule enables a chiral recognition effect on the membrane surface, thereby affording control over the enantioselective catalytic reaction of the d -glucose (D-Glu) substrate loaded inside the hybrid microcapsule. The adsorption energy of D-Glu and D-Pen (−0.095) calculated by MS is less than that of D-Glu and L-Pen (−0.064). Thus enantiomeric selective recognition is a stronger interaction force than adsorption for the same configuration. These findings highlight the development of biomimetic chiral microcompartments, and provide a platform for driving cellular chirality in various organisms.
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JOURNAL OF FOOD COMPOSITION AND ANALYSIS
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2025
·
IF 4.6
Yiyao Luo,Huan Liu,Xuhui Xia,Huizhen Fu,Mingyi Guo,Changjun Hou,Danqun Huo
Baijiu plays an essential role in Chinese food culture, but there are still certain limitations in the identification of the aroma type and brand of Baijiu. In this study, based on the Tollen’s reagent, a colorimetric sensor array was constructed for aldehydes and Baijiu discrimination. In the presence of aldehydes or Baijiu, the silver ions (Ag + ) adsorbed by negatively charged nanoparticles can be reduced to elemental silver (Ag 0 ) in situ. Ag 0 deposited on the surface of gold or silver nanopaticle (Au NPs or Ag NPs) leading to the formation of Au@Ag or Ag@Ag core-shell structure which accompanied by a color change. We developed Tollen’s reagent-based sensor array shows the outstanding detection capability in discriminating and quantifying of aldehydes. On this basis, 16 kinds of Baijiu were also identified accurately, the visual results were verified by HCA and LDA models. The colorimetric sensor developed in this study is promising for aroma recognition and brand identification of Baijiu.
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MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Weifang Jiang,Xueer Huang,Fengling Tian,Qi Wei,Kaxi Chen,Xuehui Tang,Jinfang Nie,Jianmei Zou,Di Huang,Yun Zhang
This work initially describes a highly sensitive colorimetric assay with smartphone readout that enables instrument-free, determination of hypochlorite (ClO − ) ion. The assay exploited analyte-induced anti-aggregation of Au nanoparticle (AuNP), which attenuated their Tyndall effect (TE). In the absence of the analyte, dithiothreitol (DTT) molecules (each bearing two terminal thiol groups) could form strong Au S bonds with the AuNP to induce the aggregation of these nanoprobes. This not only produced a familiar surface-plasmon-resonance-based red-to-blue color change but also markedly intensified the TE signal of the reaction mixture. In the presence of the ClO − , on the other hand, the analyte rapidly oxidized the thiol groups of DTT, thereby preventing the AuNP aggregation. These nanoprobes thus remained their original dispersed state, giving a red color and a weak TE response. The TE signal was inversely related to the ClO − concentration. Under optimized conditions, this new method, which required only an inexpensive 635 nm laser pointer to generate a red or red-yellow TE, offered far better visual discrimination of analyte concentration than the conventional SPR-based approach, reaching a visual limit of detection (LOD) of ~0.25 μM (~0.02 mg·L −1 ), ten-fold lower than that of the latter. Coupling the new assay with a smartphone for portable TE readout further allowed for linear quantification of ClO − over the 0.05–90 μM (0.0036–6.4 mg·L −1 ) range, lowering the quantitative LOD to ~14.2 nM (~0.001 mg·L −1 ) (3σ), about 30 times lower than that achieved by the traditional UV–Vis spectroscopy. The recovery of ClO − in four types of tested water samples (i.e., tap water, mineral water, pond water and pool water) ranged from 97.64 to 108.38%, additionally confirming the analytical accuracy and practical utility of the TE-enhanced smartphone-assisted equipment-free quantitative method developed herein.
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ACS Applied Materials & Interfaces
·
2015
·
IF 6.723
Chao-Ying Fan,Pin Xiao,Huan-Huan Li,Hai-Feng Wang,Lin-Lin Zhang,Hai-Zhu Sun,Xing-Long Wu,Hai-Ming Xie,Jing-Ping Zhang
In this work, the chemical interaction of cathode and lithium polysulfides (LiPSs), which is a more targeted approach for completely preventing the shuttle of LiPSs in lithium–sulfur (Li–S) batteries, has been established on the electrode level. Through simply posttreating the ordinary sulfur cathode in atmospheric environment just for several minutes, the Au nanoparticles (Au NPs) were well-decorated on/in the surface and pores of the electrode composed of commercial acetylene black (CB) and sulfur powder. The Au NPs can covalently stabilize the sulfur/LiPSs, which is advantageous for restricting the shuttle effect. Moreover, the LiPSs reservoirs of Au NPs with high conductivity can significantly control the deposition of the trapped LiPSs, contributing to the uniform distribution of sulfur species upon charging/discharging. The slight modification of the cathode with <3 wt % Au NPs has favorably prospered the cycle capacity and stability of Li–S batteries. Moreover, this cathode exhibited an excellent anti-self-discharge ability. The slight decoration for the ordinary electrode, which can be easily accessed in the industrial process, provides a facile strategy for improving the performance of commercial carbon-based Li–S batteries toward practical application.
研究领域:
储能技术
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纳米材料
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电化学
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电池技术
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ANALYTICAL CHEMISTRY
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2026
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IF 7.3
Xiaoxuan Ren,Hui Geng,Yue Sun,Shengjie Li,Guizheng Zou
Nanoparticles (NPs) are alternative chemiluminescence (CL) luminophores to molecular luminophores and are strongly anticipated to extend molecular luminophore-tagged commercial CL immunoassays (CLIA) with wavebands beyond the eye-visible region and sensitivity beyond the pg/mL level. Herein, a surficial bond-involved repetitive excitation strategy for near-infrared CL with enhanced photons per luminophore is proposed by exploiting l-methionine (l-Met)-capped gold NPs (AuNPs) as luminophores. The surficial Au–S bonds of l-Met@AuNPs can be involved in the procedure of NP core excitation via oxidation, and bring out defect-involved CL around 830 nm. Because there are plenty of Au–S bonds on every AuNP core, l-Met@AuNPs can be repetitively excited over a hundred times and give off greatly enhanced CL photons per luminophore than all molecular CL luminophores. CL of l-Met@AuNPs/(NH4)2S2O8 can directly enable automatic near-infrared CLIA for myoglobin (MYO) determination on in vitro diagnostic instruments, with a limit of detection of 10 fg/mL (S/N = 3), which significantly surpasses the threshold of molecular luminophores. This Au–S bond-triggered AuNP CL strategy not only offers an alternative to molecular CL strategies with improved sensitivity and to II–VI NP CL strategies with fewer toxic concerns, but also indicates that exploiting the surficial bond energy of NPs could be an alternative to designing NPs with unique morphology, structure, and composition in the CL domain.
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RSC Advances
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2014
·Vol. 5
·期 8
·5604-5610
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IF 3.708
Mei Yu,Jindan Zhang,Songmei Li,Yanbing Meng,Jianhua Liu
The performances of photovoltaic devices can be improved by increasing light-harvesting and charge collection respectively. The design and synthesis of nanocomposites with the ability of enhancing the generation and collection of the photo-generated electrons provide a significant way to improve the power conversion efficiency (PCE). Herein, SWNTs@(TiO2/Ag/Au) nanocomposites were synthesized and successfully integrated into photoanode films of dye-sensitized solar cells (DSSCs) to improve the power conversion efficiency. The synthesis processes were based on multi-functional DNA. DNA not only works as a dispersing agent preventing SWNTs bundling but also as a sacrificial mold assembling TiO2, Ag and Au nanoparticles on the surface of the SWNTs. The synthesized SWNTs@(TiO2/Ag/Au) nanocomposites enhance the charge collection and light-harvesting of DSSCs simultaneously. With 2.45 wt% SWNTs@(TiO2/Ag/Au) nanocomposites incorporating into the photoanode films, the PCE of the DSSCs increases from 6.8% to 8.3%.
研究领域:
材料科学
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纳米科技
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能源化学
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光伏器件
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表面科学
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胶体与界面化学
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SENSORS
·
2023
·Vol. 23
·期 5
·2870
·
IF 3.9
Qichen Tian,Yuanbin She,Yangguang Zhu,Dan Dai,Mingjiao Shi,Wubo Chu,Tao Cai,Hsu-Sheng Tsai,He Li,Nan Jiang,Li Fu,Hongyan Xia,Cheng-Te Lin,Chen Ye
A sensitive and selective electrochemical dopamine (DA) sensor has been developed using gold nanoparticles decorated marimo-like graphene (Au NP/MG) as a modifier of the glassy carbon electrode (GCE). Marimo-like graphene (MG) was prepared by partial exfoliation on the mesocarbon microbeads (MCMB) through molten KOH intercalation. Characterization via transmission electron microscopy confirmed that the surface of MG is composed of multi-layer graphene nanowalls. The graphene nanowalls structure of MG provided abundant surface area and electroactive sites. Electrochemical properties of Au NP/MG/GCE electrode were investigated by cyclic voltammetry and differential pulse voltammetry techniques. The electrode exhibited high electrochemical activity towards DA oxidation. The oxidation peak current increased linearly in proportion to the DA concentration in a range from 0.02 to 10 μM with a detection limit of 0.016 μM. The detection selectivity was carried out with the presence of 20 μM uric acid in goat serum real samples. This study demonstrated a promising method to fabricate DA sensor-based on MCMB derivatives as electrochemical modifiers.Keywords:dopamine determination;mesocarbon microbeads;gold nanoparticles;graphene nanowalls;electrochemical sensors
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MICROCHEMICAL JOURNAL
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2023
·
IF 4.8
Hongbin Pu,Yuting Xie,Qingyi Wei,Da-Wen Sun
SERS sensors based on metal-organic frameworks (MOFs) have garnered considerable attention in trace pesticide residue detection. UiO-66/AuNPs suspension substrates were fabricated by introducing thioglycolic acid (TGA) as a binder to modify the surface of AuNPs to facilitate their electrostatic assembly with UiO-66 prepared through hydrothermal reaction. The proposed substrates were used for quantitative and simultaneous analysis of paraquat and diquat in cabbage. Diquat and paraquat in actual cabbage samples were individually analysed with detection of limits (LOD) of 6 μg/L and 3 μg/L, respectively, and validated with recoveries ranging from 92.65 to 118.34%. Furthermore, the UiO-66/AuNPs substrate was able to differentiate between paraquat and diquat mixtures, even for the concentrations in the cabbage extracts differed by a factor of 100. The proposed UiO-66/AuNPs substrate provides a potentially useful tool for the trace determination of pesticide residues in the practical food safety analysis
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2023
·
IF 9.9
Nianqi Meng,Peijing Xu,Changchun Wen,Huihui Liu,Cunji Gao,Xing-Can Shen,Hong Liang
Bismuth sulfide is widely used as an n -type semiconductor material in photocatalytic reactions. However, bismuth sulfide has poor absorption in the near-infrared region and low charge separation efficiency, limiting its application in phototherapy and sonodynamic therapy (SDT). In this study, we successfully synthesized an “all-in-one” phototheranostic nanoplatform, namely Bi 2 S 3-x [email protected] , based on a single second near-infrared (NIR-II) light-responsive Schottky-type Bi 2 S 3-x -Au heterostructure for photoacoustic (PA) imaging-guided SDT-enhanced photodynamic therapy (PDT)/photothermal therapy (PTT). Bi 2 S 3-x [email protected] exhibits excellent NIR-II plasmonic and photothermal properties, rendering it with NIR-II PA imaging capabilities for accurate diagnosis. Additionally, the high-density sulfur vacancies constructed on the Bi 2 S 3 surface cause it to possess a reduced band gap (1.21 eV) that can act as an electron trap. Using the density functional theory, we confirmed that the light and ultrasound-induced electrons are more likely to aggregate on the Au nanoparticle surface through interfacial self-assembly, which promotes electron-hole separation and enhances photocatalytic activity with increased reactive oxygen species (ROS) generation. With a further modification of hyaluronic acid (HA), Bi 2 S 3-x [email protected] can selectively target cancer cells through HA and CD44 protein interactions. Both in vitro and in vivo experiments demonstrated that Bi 2 S 3-x [email protected] effectively suppressed tumor growth through SDT-enhanced PTT/PDT under a single NIR-II laser and ultrasound irradiation with negligible toxicity. Our findings provide a framework for fabricating Schottky-type heterostructures as single NIR-II light-responsive nanotheranostic agents for PA imaging-guided cancer phototherapy.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2023
·
IF 4.4
Hui-fang Du,Jian Zhu,Guo-jun Weng,Jian-jun Li,Xin Li,Jun-wu Zhao
Ligand-mediated interface control has been broadly applied as a powerful tool in constructing asymmetric multicomponent nanoparticles (AMNP), and induces the anisotropic growth with fine-tuning morphology, composition, plasmonic property and functionality. As a new kind of AMNP, the synthesis of Janus Au-Ag nanoparticles with tunable negative surface curvature is still a challenge. Here, we demonstrate that the synergistic surface energy effects between gold nanodumbbells (Au NDs) with a negative surface curvature and 4-mercaptobenzoic acid (4-MBA) can direct the site-selective growth of anisotropic silver domains on gold nanodumbbells (Au NDs@Ag NPs). By adjusting the 4-MBA concentration-dependent interfacial energy, the Au NDs@Ag NPs could be continuously tuned from dumbbell-like core–shell structures, to L-shaped Janus, and then rod-like core–shell structures with directional and asymmetric spatial distributions of resizable Ag domains by site-selective growth. Based on the calculation results of discrete dipole approximation (DDA) method, it has been found that the Au NDs@Ag L-shaped Janus NPs with Ag island domains created polarization orientation-dependent plasmonic extinction spectra and hot spots around the negatively curved waist and Ag domains. The L-shaped Janus Au NDs@Ag NPs exhibited significantly plasmonic spectrum properties with four apparent LSPR peaks that cover from visible to near-infrared range and higher surface-enhanced Raman scattering (SERS) activity compared with the original Au NDs. The best SERS enhancement factor of 1.41 × 10 7 was achieved. This synergistic surface energy effect-based method involving the asymmetric growth of silver coating on gold nanoparticles with negatively curved surface presents a new method to design and fabricate nanometer optical devices based on asymmetric multicomponent nanoparticles.
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FOOD CHEMISTRY
·
2023
·
IF 8.8
Hongguo Zhai,Yue Wang,Lingjun Geng,Qi Guo,Yuhao Zhang,Qingqing Yang,Xia Sun,Yemin Guo,Yanyan Zhang
In this paper, an electrochemiluminescence (ECL) biosensor was constructed using Bi 2 S 3 @Au nanoflowers as the based nanomaterial and [email protected] and CdS QDs as independent ECL emission signal respectively. As the substrate of the working electrode, Bi 2 S 3 @Au nanoflowers improved the effective area of electrode and accelerated electron transfer rate between gold nanoparticles and aptamer, provided a good interface environment for the loading of luminescent materials. Then, the [email protected] functionalized DNA2 probe was used as an independent ECL signal source under positive potential and recognized Cd(II), while the CdS QDs functionalized DNA3 probe was used as an independent ECL signal source under negative potential and recognized ampicillin. The simultaneous detection of Cd(II) and ampicillin in different concentrations are realized. This sensor not only has good selectivity and high sensitivity in real sample detection, but also open up a novel way to construct multi-target ECL biosensor for simultaneous detection.
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BIOCONJUGATE CHEMISTRY
·
2022
·
IF 6.069
Chunxiao Sui,Rui Tan,Zifan Liu,Xiaofeng Li,Wengui Xu
Imaging-guided photothermal therapy (PTT) in a single nanoscale platform has aroused extensive research interest in precision medicine, yet only a few methods have gained wide acceptance. Thus, it remained an urgent need to facilely develop biocompatible and green probes with excellent theranostic capacity for superior biomedical applications. In this study, a smart chemical oxidative polymerization strategy was successfully developed for the synthesis of Au@PPy core–shell nanoparticles with polyvinyl alcohol (PVA) as the hydrophile. In the reaction, the reactant tetrachloroauric acid (HAuCl4) was reduced by pyrrole to fabricate a gold (Au) core, and pyrrole was oxidized to deposit around the Au core to form a polypyrrole (PPy) shell. The as-synthesized Au@PPy nanoparticles showed a regular core–shell morphology and good colloidal stability. Relying on the high X-ray attenuation of Au and strong near-infrared (NIR) absorbance of PPy and Au, Au@PPy nanoparticles exhibited excellent performance in blood pool/tumor imaging and PTT treatment by a series of in vivo experiments, in which tumor could be precisely positioned and thoroughly eradicated. Hence, the facile chemical oxidative polymerization strategy for constructing monodisperse Au@PPy core–shell nanoparticles with potential for cancer diagnosis and imaging-guided photothermal therapy shed light on an innovative design concept for the facile fabrication of biomedical materials.
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