LIVER INTERNATIONAL
·
2025
·Vol. 45
·期 3
·e70024
·
IF 5.2
Guqing Luo,Zhenghao Wu,Qiang Fan,Chihao Zhang,Jiayun Lin,Hongjie Li,Jinbo Zhao,Haizhong Huo,Xiaoliang Qi,Guangbo Wu,Min Chen,Jiwei Yu,Lei Zheng,Meng Luo
Background and Aims Lymphangiogenesis is enhanced during the development of liver cirrhosis and portal hypertension (PHT). However, hepatic lymphatic vascular system is understudied in liver cirrhosis and PHT. Hydrogen sulfide (H 2 S) and related compounds have potential prolymphangiogenic effects besides its previously reported vascular-protective effects. Therefore, we aimed to investigate the effects of endogenous H 2 S donor S-allyl-cysteine (SAC) on bile duct ligation (BDL)-induced liver cirrhosis and PHT. Methods BDL rats with cholestatic liver cirrhosis and PHT were orally administrated with SAC at 100 or 200 mg/kg/day, as well as DL-propargylglycine (PAG) or MAZ-51 injections. Hemodynamic parameters were determined, and subsequent evaluations of liver fibrosis, intrahepatic vascular resistance (IHVR) and lymphangiogensis were performed. Human lymphatic endothelial cells (hLECs) were used for in vitro verification of prolymphangiogenic effects of SAC. Results SAC treatment significantly decreased PP and promoted endogenous H 2 S production. Liver fibrosis and IHVR were also ameliorated. Hepatic and mesenteric lymphangiogenesis were enhanced in BDL rats and further promoted by SAC despite a significant downregulation of hepatic VEGF-C. Inhibition of H 2 S production by PAG significantly reduced lymphatic vessels, while inhibition of lymphangiogensis by MAZ-51 reversed the protective effects of SAC against PHT. SAC enhanced lymphangiogenic functions in vitro by promoting cellular H 2 S production and activating Akt phosphorylation without altering VEGF-C/D, which were reversed by PAG and MAZ-51. Conclusions SAC significantly alleviated BDL-induced liver cirrhosis and PHT. Meanwhile, elevated H 2 S induced by SAC facilitated lymphangiogenesis via a VEGF-C-independent manner, which contributed to the alleviation of PHT.
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PubMed
高影响因子
ACS Applied Nano Materials
·
2024
·
IF 5.3
Wenwen Deng,Shaocong Ni,Naiqi Hu,Ying Zhou,Zhong Jin
Silicon oxide (SiOx) has been widely studied due to its ultrahigh theoretical specific capacity for lithium storage. However, its inherent low electronic conductivity and large volume change before and after lithium insertion have limited its commercialization. To address this issue, we report the synthesis of SiOx@ZrO2@C ternary composite nanospheres by convenient and scalable wet chemistry and sintering processes. In the unique structure of 3D porous SiOx@ZrO2@C nanospheres, zirconium oxide (ZrO2) supplies high structural stability, while the amorphous carbon (C) layer helps to form a stable solid–electrolyte interface, suppress volume expansion, and greatly improve the conductivity. Electrochemical measurements demonstrate that the SiOx@ZrO2@C nanospheres exhibit a capacity retention of 72.2% after 500 cycles at 500 mA g–1. At a high current density of 800 mA g–1, the SiOx@ZrO2@C nanospheres can still deliver a capacity of 529.1 mAh g–1. This work provides a promising mass-scale synthesis method for producing SiOx composites and introduces a high-performance anode material for lithium-ion batteries.
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Crystals
·
2024
·Vol. 14
·期 3
·279
·
IF 2.4
Yang Wu,Hao Lan,Xiaoming Sun,Zihao Hu,Yonghui Sun,Huifeng Zhang,Chuanbing Huang,Weigang Zhang
HfO2has become a promising thermal barrier coating material due to its similarity in structure and chemical properties with ZrO2and its higher phase structure transition temperature. However, the fracture toughness of HfO2is not ideal, greatly limiting its application. In this report, we find a special sandwich structure of ceramics, comprising a cubic (C) phase /monoclinic (M) phase/cubic (C) phase. The microstructural evolution and mechanical properties of these ceramics were investigated under annealing at 1500 °C. The results indicate that, with an increase in annealing duration, there was a gradual augmentation in the proportion of the monoclinic (M) phase and the fracture toughness increased from 2.18 MPa·m0.5to 2.83 MPa·m0.5after 48 h of annealing, which is higher than many potential TBC materials. The residual compressive stress present in the M phases during the progression of crack propagation served to facilitate the bridging and deflection of cracks. As such, this process led to the alleviation of stress concentration at the crack tip, ultimately enhancing the toughening effect.
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Journal of Energy Storage
·
2025
·
IF 9.8
Dan Lv,Lili Yang,Runfeng Song,Mingtao Ding,Jie Liu,Wenbin Hu,Cheng Zhong
Silicon (Si)-based anode materials have been regarded as a viable alternative to replace traditional graphite owing to its high theoretical capacity. Nevertheless, the industrial production of Si nanoparticles (Si NPs) is hindered by low tap density and inferior areal capacity. Here, the hard carbon supported Si NPs are encapsulated by soft carbon and Al 2 O 3 to fabricate HC@Si@SC@A sample for high performance lithium-ion batteries (LIBs). Micrometer-sized HC serves as size regulator for Si NPs and SC serves to improve electric conductivity and suppress volume changes. With the existence of Al 2 O 3 , a thin and inorganic components-rich solid electrolyte interphase (SEI) has formed, greatly maintaining the stability of electrode during cycling. Therefore, the HC@Si@SC@A anode delivers an ultrahigh discharge capacity of 14.5 mAh cm −2 at 0.2 A g −1 . It can show excellent performance as an anode of full cells with the NCM811 as the cathode material.
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JOURNAL OF CATALYSIS
·
2025
·
IF 6.5
Shiqi Chen,Xinyu Wang,Can Liu,Jiapeng Yue,Zhiwei Yang,Qian Ye,Hao Xu,Yujian Zhang,Xinyi Xing,Jing Zhang
Rational design and controllable synthesis of oxygen functional groups on carbon/metal catalysts surface as the effective means to enhance catalytic performance, however, still remains a great challenge. Herein, to obtain the relationship between oxygen functional groups and catalytic performance, taking MoO 2 -C as an object, the correlation between the C=O, C-O, Mo O bonds and strengthened iron reduction is quantitatively assessed, with electrochemical experiments validating that this relationship arises from its influence on the electron transport process, specifically concerning the roles of electron donors and mediators. The metal–oxygen and C-O bonds synergistically enhance electron transport, whereas the C=O and C-O bonds exhibit an antagonistic effect on electron-mediated processes. The influence of the metal–oxygen bonds was found to stem from their role as an electron donor, while the carbon–oxygen bonds primarily modulate the material’s catalytic properties by altering its electron transfer characteristics. In this study, the C-O, C=O bonds, and metal–oxygen bonds, as the typical surface oxygen functional groups, were identified the mechanism by changing the electron supply and mediation to enhance the Fe 3+ reduction reaction in the Fenton system, which provided theoretical support and design ideas for the design of catalyst with excellent catalytic properties.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Xuexue Zhang,Jing Wang,Weiwei Wang,Cao Wu,Chang Liu,Hailiang Deng,Liyan Wei,Weihua Gu,Wenbo Du,Yanning Chen,Hongwei Liu,Xun Cao
Using air/SiO 2 @Fe/C yolk-shell nanospheres (NSs) absorbers as a carrier, this research studies the coupling relationship between low-frequency electromagnetic wave (EMW) absorption performance and construction of materials with dual-sized pores and dual-component. Endured via synergistic process of pyrolysis and etching, the sizes of large cavities (∼ 200 nm) and mesopores (∼ 10 nm) were finely tuned at near-atomic scales. In addition, plenty of polarization attenuation structures (e.g., cavities/carbon, cavities/silica, iron/carbon and defects) were also generated. Results revealed that construction of multi-scale pores has slender contribution on the peak reflection loss (RL min ) values, while EMW absorption in the low-frequency range was obviously enhanced. The resulted H12 sample presented a resonance reductions at 6.72 GHz with the RL min value of −22.4 dB, which shifted ∼9.8 GHz towards lower frequencies compared to H0 (-20 dB, 16.52 GHz). This case can be elucidated via the resonance mechanism of cavity, where the air/SiO 2 @Fe/C yolk-shell NSs function as dielectric resonators. This work offers a novel way to design the micro/nano-scale pores in carbon-based EMW-absorbing materials, and a promising approach to develop materials designed for low-frequency EMW absorption.
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Energy Storage Materials
·
2024
·
IF 18.9
Shengkai Mo,Hanwen An,Qingsong Liu,Jiaming Zhu,Chuankai Fu,Yajie Song,Jiajun Wang
The practical application of solid-state batteries (SSBs) has been significantly hampered by the sluggish Li + transport dynamics in cold climates. In particular, SSBs suffer from insufficient dynamics due to poor electrolyte-electrode interface compatibility at low temperatures. Herein, a multistage bridge engineering for electrolyte and interface is proposed to improve the Li + transfer kinetics, which enables quasi-solid batteries to operate at low temperatures. The incorporation of siloxane segments allows the electrolyte to polymerise uniformly and improves Li + transport. The multistage bridging structure improves the electrode-electrolyte interfacial interaction, accelerating Li + transfer kinetics at low temperatures. The obtained Li||LiNi 0.8 Co 0.1 Mn 0.1 O 2 (NCM811) cell delivers a high coulombic efficiency of 99.98 % and a specific energy of 266 Wh⋅kg −1 at -40 °C. This multistage bridge engineering strategy provides a new perspective for polymer electrolyte design towards stable operation of quasi-solid batteries at low temperatures.
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COMBUSTION AND FLAME
·
2025
·
IF 6.2
Shubao Song,Lin Zhang,Meishuai Zou,Jiankun Shao
High-temperature gas-phase interactions between chlorine- and nitrogen-bearing species relevant to ammonium-perchlorate (AP) propellant combustion were elucidated by coupling shock-tube laser-absorption measurements with a detailed kinetic model. Time-resolved HCl concentration profiles were obtained for four argon-diluted surrogates—0.3 % NH 3 /0.3 % CCl 4 , 0.5 % NH 3 /0.3 % CCl 4 , 0.2 % NH 3 /0.2 % CCl 4 /0.2 % CH 4 , and 0.2 % NH 3 /0.2 % CCl 4 /0.2 % H 2 —over 1158–1506 K at near-atmospheric pressure. A kinetic model consisting of 164 species and 1358 reactions, assembled from state-of-the-art CCl 4 , H–Cl–O, NH 3 /C 0 –C 2 , and N–Cl sub-models, reproduced the new HCl data alongside literature ignition-delay and speciation measurements with excellent accuracy. Sensitivity and rate-of-production analyses reveal a temperature-robust control structure in which HCl forms almost entirely through Cl-atom abstraction from NH 3 , with Cl supplied by rapid CCl 4 dissociation; the barrierless Cl + H<=>HCl path dominates in H 2 -containing mixtures, whereas competition from Cl + CH 4 <=>CH 3 + HCl moderates HCl growth and channels carbon–nitrogen flux toward toxic HCN when CH 4 is present. Elevated temperature chiefly amplifies Cl production and suppresses NH 2 recombination, accelerating overall reactivity without altering the dominant pathways. The resulting benchmark HCl time-histories and rigorously validated model advance fundamental understanding of chlorine–nitrogen combustion chemistry and provide quantitative guidance for formulating halogenated energetic materials that maximise performance while limiting hazardous by-product formation. Importantly, the mechanism developed here may serve as a transferable gas-phase sub-model for future integration into comprehensive AP combustion frameworks, enabling more predictive simulations of real propellant systems.
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Nanoscale
·
2025
·
IF 5.1
Chuangxin Zhou,Zhiheng Zhang,Yuan Gao,Weize Diao,Siyi Zou,Jun Zhu,Jiangtao Xu,Guozhen Liu
Surface modification of Eutectic Gallium Indium (EGaIn) to inhibit oxidation has been a long-lasting challenge in material science, with limited research reporting the formation of a covalent bond between Ga and modifiers for stability purposes. Taking advantage of strong reductive property of EGaIn, this study developed a simple method for spontaneous reduction of aryldiazonium salts on EGaIn nanoparticle surface to form stable covalent Ga-C sigma bonds, effectively suppressing surface oxidation.Comprehensive characterization confirmed the formation of the covalent Ga-C bond rather than Ga-N=N-C bonds on the EGaIn nanoparticle surface. Approximately 20% of Ga(0) in EGaIn forms Ga-C bonds. Notably, the short chain aryl modified EGaIn nanoparticles exhibited high stability and negligible surface oxidation. This straightforward strategy for preparing stable aryl modified EGaIn nanoparticles allows the introduction of a range of ligands on the EGaIn nanoparticle surfaces, offering promising opportunities for diverse applications across multiple fields.
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MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
·
2025
·
IF 7
Shengbin Dai,Jiangqi Zhu,Shun Wu,Martin Heilmaier,Yuman Zhu,Xingchen Yan,Aijun Huang
The retention of dislocation cellular patterns (DCPs) in laser powder bed fusion (LPBF) processed metals offers a novel pathway for achieving strength-ductility balance in high-temperature applications. This study innovatively combines oxide dispersion strengthening (ODS) with tailored heat treatment to stabilize DCPs in Inconel 718 (IN718) superalloys. Through strategic introduction of yttrium oxide (Y 2 O 3 ) nanoparticles (average diameter ≈40 nm) and optimized solution treatments (1200 °C for 5min/1 h), we resolve the inherent conflict between residual stress elimination and microstructure preservation in LPBF-fabricated components. The 5-min treated ODS alloy achieves exceptional synergy at 650 °C: yield strength maintains 600 MPa while ductility increases 45 % (from 20 % to 29 %) compared to as-built specimens. Crucially, our approach demonstrates two key innovations: 1) Y 2 O 3 nanoparticles effectively pin dislocations movements, preserving DCPs structure against thermal coarsening; 2) Ultra-short heat treatment duration enables complete Laves phase dissolution without compromising dislocation network integrity. Microstructural analysis confirms that the stabilized DCPs-Y 2 O 3 composite architecture facilitates simultaneous stress and strain accommodation. This work establishes a new paradigm for designing high-performance LPBF alloys through coupled process-microstructure optimization, particularly for aerospace components requiring elevated temperature mechanical stability.
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INORGANIC CHEMISTRY COMMUNICATIONS
·
2025
·
IF 5.4
Biao Li,Yuqi Liu,Baizhuang Li,Yusi He,Yufeng Zhang,Xinying Wang,Yuebin Feng,Wei Li
Tetracycline (TC) antibiotics in aquatic environments pose severe ecological and health risks due to their difficult biodegradability and environmental accumulation. Persulfate-based advanced oxidation process (PS-AOP) has been proven to be a promising method for TC degradation in wastewater treatment but requires efficient, stable catalysts. Herein, three melamine-modified POM@MOF composites WCo@C-1, WCo@C-5 and WCo@C-10 (WCo-PMOFs and melamine in mass ratios of 1:1, 1:5, and1:10, respectively) were synthesized by calcining a mixture of WCo-PMOFs and melamine, which were used as catalysts for peroxymonosulfate (PMS) activation to degrade TC efficiently. The results demonstrated that the TC degradation rate by WCo @ C-10 activated persulfate (PMS) reached 95.83 % within 2 h superior to that of WCo@C-1 and WCo@C-5 under the same experimental conditions. Notably, the WCo@C-10/PMS system exhibited exceptional cycling stability, maintaining a degradation efficiency of 83.51 % even after four consecutive cycles. The X-ray photoelectron spectroscopy (XPS) and electrochemical impedance spectroscopy (EIS) characterization results indicate that the WCo@C-10 composite material exhibits outstanding catalytic performance. This characteristic is mainly attributed to the significant improvement in the material's dispersion and its having the smallest impedance arc radius among a series of materials, which reflects a lower charge transfer resistance and excellent electrical conductivity. These characteristics synergistically promote the efficient conversion of Co(III) to Co(II). The quenching experiment combined with electron paramagnetic resonance (EPR) analysis confirmed that superoxide radicals (O 2 ·- ) and singlet oxygen ( 1 O₂) are the main reactive oxygen species in this system. This study provides a new idea for designing efficient PMS-based advanced oxidation systems.
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JOURNAL OF MATERIALS SCIENCE
·
2024
·Vol. 59
·期 22
·9941-9951
·
IF 3.5
Zeng Dawei,Zhou Jiaxin,Wu Zhen,Sun Luchao,Wang Jingyang
Ultra-high temperature ceramics (UHTCs) are considered as promising thermal insulation materials applied in ultra-high temperature environments (> 2000 °C). However, the high thermal conductivity and high density limit their further development and application. Herein we adopt the strategies of introducing porous structure and high-entropy effect to solve the above problems. Thus porous high-entropy (Zr 0.25 Hf 0.25 Nb 0.25 Ti 0.25 )C ceramics were prepared. In order to obtain the uniform pore structure and high mechanical property, the camphene-based freeze-casting method was used in this study. The as-prepared porous samples exhibit high porosity of 92.01–73.57% and homogeneously interconnected pore structure with average pore size of 40.8–19.6 μm. Besides, this work realizes the aims of lightweight (0.65–2.15 g/cm 3 ) and low thermal conductivity (0.29–1.53 W/(m·K)). More importantly, porous samples still have the merit of high compressive strength (0.38–29.02 MPa) due to the even microstructure. The results show that highly porous high-entropy (Zr 0.25 Hf 0.25 Nb 0.25 Ti 0.25 )C with good overall properties can be an excellent candidate material for ultra-high temperature thermal insulation.
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