LANGMUIR
·
2025
·
IF 3.9
Dandan Liu,Hui Zhang,Jinfeng Mei,Xudong Zheng,Jian Rong,Zhongyu Li
A three-dimensional porous aerogel was synthesized by combining soft chitosan oligosaccharide to hard multi-walled carbon nanotubes (MWCNTs) under mild conditions. Owing to the support of MWCNTs, mesopores can be detected on the inner surfaces of the aerogel. The cross-linking by tetraethylenepentamine forms a macropore structure after freeze drying, using water as the template. The hydrogel can bear 30% recoverable compression with the aid of hydrogen bonds between the amide groups. The aerogel exhibits excellent adsorption capabilities for Cr(VI) in water. The adsorption capacity can reach 367.6 mg/g within 100 min. Notably, the aerogel demonstrated an extremely high efficiency in removal for trace Cr(VI). Soluble Cr(VI) of 1 mg/L can be completely removed by the aerogel at a dosage of 0.2 g/L. This work provides a new strategy to synthesize adsorbents with hierarchical pores that exhibit high porosity and a fast mass transfer rate.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Jing Li,Xiaoqin Shi,Kang Yang,Lang Guo,Junjie Yang,Zhengyu Lan,Yong Guo,Longquan Xiao,Xinhui Wang
In this study, carvacrol was effectively encapsulated in gelatin/chitosan composite nanofiber membrane using the electrospinning method with the help of the cationic surfactant cetyltrimethylammonium bromide (CTAB). The effects of CTAB (0.0%, 1.0%, w/w) and bioactive carvacrol (0.0%, 1.0%, 3.0%, 5.0%, 7.0%, 10.0%, w/w) on the structural, physicomechanical, antibacterial, and antioxidant characteristics of the nanofiber membranes were investigated. The results demonstrated that the antibacterial and antioxidant characteristics of the gelatin/chitosan composite nanofiber membrane (GC) and GC-CAR membrane (with the addition of 1.0% carvacrol) were unsatisfactory. As carvacrol and CTAB were both added, the elongation at break, antibacterial, and antioxidant properties of the nanofiber membranes significantly improved (p < 0.05), while the water vapor permeability (WVP) significantly decreased (p < 0.05). When the added amount of carvacrol was 5.0% (w/w), the nanofiber membrane (GC-CAR5-CTAB) exhibited the best antioxidant and antibacterial performance. Finally, the GC-CAR5-CTAB membrane was applied to the preservation of strawberries and Erjingtiao chilies, and their shelf life was effectively extended. The above results indicate that the nanofiber membrane prepared in this study has great potential for application in food-active packaging.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2024
·Vol. 14
·期 15
·10410-10415
·
IF 3.9
Jingjing Zhao,Dou Qian,Luyang Zhang,Xiao Wang,Jianfeng Zhang
Epigallocatechin gallate (EGCG) has attracted increasing attention thanks to its multi-bioactivities, and people are keen on improving the antioxidative and antibacterial performance of EGCG. Based on the favorable biofunctionality of Zn2+ and chitosan (CS), an EGCG derivative with a novel formula, i.e., EGCG–Zn–CS, is presented in this study. The structure of EGCG–Zn–CS was characterized by FT-IR, UV-vis, TGA, XPS, and SEM–EDS. The radical elimination results indicate that 0.1 mg mL−1 of EGCG–Zn–CS demonstrates DPPH radical and hydroxyl radical scavenging activities of 94.8% and 92.3%, while 0.1 mg mL−1 of EGCG exhibits only 78.5% and 75.6%, respectively, which means improved antioxidative activity of EGCG–Zn–CS was obtained. Inhibitory experiments against Staphylococcus aureus and Escherichia coli reveal that the minimal inhibitory concentrations (MICs) of EGCG–Zn–CS were 15.625 μg mL−1 and 187.5 μg mL−1, whereas the minimal bactericide concentrations (MBCs) were 46.875 μg mL−1 and 750 μg mL−1, respectively, which indicate that EGCG–Zn–CS exerts much higher antibacterial activity than EGCG. It can be concluded that the complexing of zinc cations and CS could amazingly improve both the antioxidative and antibacterial activity of EGCG, and it is expected that an exploration of EGCG–Zn–CS may inspire the development of simultaneous effective antioxidant and antibacterial agents.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CARBOHYDRATE POLYMERS
·
2024
·
IF 10.7
Haoxin Cai,Jiaojiao Yan,Weiguang Zhao,Shuai Ma,Jun Wu,Ze Zhao,Hongbing Deng
Injectable hydrogels with heterogeneous fibrous structures possessing good mechanical and biological characteristics are attracting increasing research interest in cartilage repair. The integration of nanofibers into hydrogel would largely enhance mechanical property, but impedes the gelation process and formation of hydrogel structures. Construction of biocompatible and mechanical supporting hydrogel with low fiber content remains a challenge. In this study, we developed a chemical cross-linked fibrous hydrogel, namely Thiol chitosan-Poly (lactic- co -glycolic acid)-Polydopamine (CSSH-PP), for facilitating cell proliferation and promoting cartilage tissues regeneration. Compared to conventional CSSH hydrogels, the compressive strength of CSSH-PP scaffolds exhibited a significant increase percentage of 100 %. Incorporation of CSSH-PP upgraded the cell migration with a four-fold increase. Besides, the infiltration of host cells and the formation of new blood vessels were observed in rat models when implanted with CSSH-PP, enhancing the native tissue microenvironmental reconstruction and leading a sustained repair in articular cartilage.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2024
·
IF 5.7
Kangning Wang,Hui Sun,Zhihan Cui,Jiahui Wang,Jiayi Hou,Fuping Lu,Yihan Liu
In this work, lactoferrin (LF)–chitosan (CS) composite hydrogels with good loading capacity of thermosensitive bioactive substances were successfully obtained by microbial transglutaminase (MTG)-induced cross-linking. We evaluated the rheological, textural, and microstructural characteristics of the composite hydrogels under different conditions. The results demonstrated that the concentrations of LF and CS as well as the amount of MTG could regulate the textural properties, rheological properties, and water holding capability. The results of FTIR and fluorescence spectroscopy indicated that the main interactions within the composite gel were hydrogen and isopeptide bonds. Additionally, in vitro digestion simulation results verified that riboflavin kept stable in stomach due to the protection of LF–CS composite hydrogels and was released in small intestine. These results suggested that thermosensitive bioactive substance could be encapsulated and delivered by the LF–CS composite hydrogel, which could be applied in lots of potential applications in functional food as a new material.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Today Communications
·
2024
·
IF 3.7
Xiaoyan Li,Fuxun Qi,Jixiang Zhu,Xinsheng Niu,Shengbing Yang,Deng-Guang Yu
Constructing bio-based antibacterial composite multilayer coatings with sustained drug release is important for reducing the infection risk of bone tissue repair. In this paper, a layer-by-layer aqueous electrodeposition method was applied to prepare a bio-based composite coating of chitosan, hyaluronic acid, and chitosan quaternary ammonium salt on the titanium surface. By pretreating with poly (acrylic acid), controlling the electrochemical deposition process, and post-treating with glutaraldehyde, a multi-layer composite coating with a smooth surface, good interface bonding with the titanium substrate, and a thickness more than ten microns was obtained. The composite coating was used as a drug-carrying system for gentamicin sulfate, which showed obvious antibacterial effects against Escherichia coli and Staphylococcus aureus . The bio-based composite coating with a sandwich structure loaded with antibiotics effectively inhibited the burst release of antibiotics, and the 14-day release rate is only 68.4 ± 2.1 %, achieving sustained release of the drug. The hydrophilic chitosan quaternary ammonium salt on the surface of the composite coating can effectively inhibit the early adhesion of bacteria, while the slow release of gentamicin sulfate in the interlayer can exert a long-lasting antibacterial effect. The preparation of bio-based antibacterial composite coatings using a layer-by-layer electrodeposition strategy has promising applications in titanium orthopedic implants.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Hao Yuan,Zhaoxiang Zeng,Dongru Li,Rongzeng Huang,Wan Li
Puerarin (PUE), a natural and biologically active isoflavone extracted from Chinese medicine Pueraria lobata , can self-assemble to form a hydrogel without other chemical modifications. However, although PUE hydrogel has pH responsivity, but it is difficult to adapt to the changeable pathological environment. Therefore, thiolated chitosan (TCS) is synthesized and hybridized with PUE hydrogel to prepare TCS 10 /PUE composite hydrogel. The results of rheological measurement showed that the resultant composite hydrogels inherited the low loss performance of TCS hydrogel, which means that they have stronger elasticity. Transmission electron microscopy (TEM) and scanning electron microscopy (SEM) images displayed that TCS 10 /PUE composite hydrogel has a fibrous-network structure. X-Ray Diffractometer (XRD) and Fourier transform infrared spectroscopy (FT-IR) proved the existence of hydrogen bonds and disulfide bonds in the formation of composite hydrogel. Degradation experiment showed that TCS 10 /PUE composite hydrogels have pH and glutathione (pH/GSH) dual sensitivity. Furthermore, TCS 10 /PUE composite hydrogels exhibited multi-functionality including thixotropy, cytocompatibility, antibacterial and anti-inflammatory properties. Berberine chloride hydrate (BCH) was further used as a model drug for in vitro release study. BCH and PUE could be released cooperatively under pH/GSH dual responsivity. These results indicated that the resultant composite hydrogel has eminent pH/GSH dual responsivity and could act as a potential new intelligent drug carrier.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Qianwen Xue,Weihao Wu,JiangQin Wu,Yuxuan Zhang,Xiaofang Gao,Zaosheng Lv,Yang Lei,Yanfen Huang
Superhydrophobic coatings are ideal for industrial applications involving oil spill cleaning, de-icing, anti-fouling, and anti-icing. The majority of current superhydrophobic coating preparation techniques have significant costs and pollute the environment, which are incompatible with the principles of sustainable green development. In this study, we produced a superhydrophobic coating based on the low-cost green material chitosan, Fe 3 O 4 nanoparticles, and octadecylamine, which possesses photothermal characteristics and magnetic oil-water separation properties. Among these, octadecylamine supplied a lower surface energy and nano-Fe 3 O 4 supplied the coating's surface roughness structure. Under simulated sunlight, the fabricated coatings produced a pronounced photothermal effect. The surface temperatures of the polyurethane sponge coating and the cotton fabric coating rose to 144.6 °C and 117.5 °C, respectively, after just 5 min. Furthermore, the coatings can be used for magnetically-driven oil-water separation with a certain degree of recyclability. The oil-water separation efficiency of the coating can reach 92% and above. More importantly, the coating also has excellent mechanical stability and self-cleaning properties. Therefore, this cheap and environmentally friendly nano-Fe 3 O 4 /chitosan-based superhydrophobic coating has great potential for application.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Hao Wu,Peng-rui Du,Xiao-ran Miao,Rui-quan Hou,Sheng-nan Li,Muhammad Zeeshan,Jin-cheng Liu,Su-qing Huang,Dong-mei Cheng,Han-hong Xu,Zhi-xiang Zhang
Water stress, a significant abiotic stressor, significantly hampers crop growth and yield, posing threat to food security. Despite the promising potential of nanoparticles (NPs) in enhancing plant stress tolerance, the precise mechanisms underlying the alleviation of water stress using O -Carboxymethyl chitosan nanoparticles ( O -CMC-NPs) in maize remain elusive. In this study, we synthesized O -CMC-NPs and delved into their capacity to mitigate water stress (waterlogging and drought) in maize seedlings. Structural characterization revealed spherical O -CMC-NPs with a size of approximately 200 nm. These NPs accumulated near the seed embryo and root tip, resulting in a substantial increase in fresh and dry weights. The application of O -CMC-NPs to water-stressed maize seedlings remarkedly elevated the chlorophyll content and activity of various antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), peroxidase (POD), and polyphenol oxidase (PPO). The malondialdehyde (MDA) content was significantly reduced compared to the untreated control. Additionally, the expression of stress-responsive genes, such as ZmSOD , ZmCAT, ZmPOD , ZmTIFY , ZmACO , ZmPYL2 , ZmNF-YC12, and ZmEREB180 , were significantly upregulated in the O -CMC-NPs treated seedlings. These findings unveil the novel role of O -CMC-NPs in enhancing plant stress tolerance, suggesting their potential application in safeguarding maize seedlings under water stress conditions and facilitating the recovery from oxidative damage.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Results in Chemistry
·
2025
·
IF 4.2
Lifeng Yang,Pinjin Zheng,Zexin Chen
The aim of this research is to explore new techniques for preparing a cross-linked three-dimensional network nanogel structure (CS-NPS) loaded with bifendate (DDB). The ionic cross-linking method was used to prepare CS-NPS from tripolyphosphate (TPP) and chitosan (CS), and DDB was then encapsulated in the nanogel structure to obtain DDB-CS-NPS. The preparation conditions were optimized through single-variable experiments and the Box–Behnken response surface method to obtain DDB-CS-NPS with good system stability, moderate particle size, and good encapsulation efficiency. It was found that when the TPP concentration was 1.5 mg/ml, the feed ratio was 3.8:1, and the ultrasound treatment time was 10 min and 53 s, the encapsulation efficiency predicted by the Box–Behnken response surface method could reach 89.38 %. A verification test showed that the actual average encapsulation efficiency of the DDB-CS-NPS reached 88.64 %, and the deviation between the predicted and the actual values was −0.8220 %. The average particle size of the samples was 644.8 nm, the polydispersity index was 0.301, and the zeta potential was 6.68 ± 1.29 mV. The results indicate that the proposed preparation process is feasible, the response surface test model can accurately predict the preparation condition area of DDB-CS-NPS, the deviation between the predicted encapsulation efficiency and the actual value is small, and the encapsulation efficiency meets the expected requirements. The DDB-CS-NPS obtained has a moderate particle size, a uniform distribution, and a relatively low potential. However, it may be prone to aggregation or coagulation, and so should be stored in a refrigerated condition.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Wenzhang Huang,Xin Zhang,Zhen Yu,Chenxi Sun,Tikun Shan,Zhenxiu Zhang
The aim of this study was to achieve rapid gelation of chitosan (CS) and silica (SA) without crosslinking agent, the relationship between process parameters and the composite aerogels properties were also explored. By varying the composition ratio of the system (from SA:CS = 1:1 to 5:1), the system gelation time was reduced by >12 times, and the drying shrinkage of the composite aerogel reached a minimum of 7.6 %. During the two recombination processes, chitosan rapidly formed aqueous colloid secondary structure under the influence of ethanol. This phenomenon reduced the stability of the system and allowed silica to form a two-phase composite hydrogel. Because the network gap between the fibers was used as a limiting medium for gel growth. In addition, the chitosan/silica composite aerogels exhibited a mesoporous structure with low density (0.1144 g/cm 3 ), and the thermal conductivity was 0.028 W/(m·K) at 30 °C. The trimethylchlorosilane made the composite aerogel have good hydrophobicity with water contact angle as 134.7°, and the adsorption capacity of carbon tetrachloride could reach >10 times of its own weight. This study provides an eco-friendly and high-efficiency method for preparing aerogels, which has potential applications in the fields of thermal insulation, oil-water separation, etc.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2025
·
IF 3.7
Xiaoqian Peng,Shaojun Liu,Jing Zhang,Xu Zhang,Xiaochan Liu,Zhipeng Yuan,Guoran Liu,Xibin Yi,Serguei Filatov
It is well known that adsorbent material is the key to determine the CO 2 adsorption performance. Herein, ZIF-8 derived porous carbon (ZIF-8-C) is anchored into the framework of a novel composite aerogel (ZCPx), which utilizes chitosan (CS) and polyvinyl alcohol (PVA) as raw materials. By controlling the ratio of ZIF-8-C, the developed hierarchical porous structures combine the advantages of micropores, mesopores, and macropores. Besides, the ligand material of ZIF-8-C and the amino group from CS are two sources of the high nitrogen content of ZCPx. The optimized sample ZCP4 shows a high nitrogen content of 6.78 %, which can create more active centers and supply basic sites, thereby enhancing the CO 2 adsorption capacity. Moreover, ZCP4 composite aerogel presents a CO 2 adsorption capacity of 2.26 mmol·g −1 (298 K, 1 bar (equivalent to 100 kPa)) and CO 2 /N 2 selectivity (S CO2/N2 ) can reach 20.02, and the dynamic breakthrough experiment is performed to confirm the feasibility of CO 2 /N 2 actual separation performance, proving that the composite aerogel is potential candidates for CO 2 adsorption.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）