SEPARATION AND PURIFICATION TECHNOLOGY
·
2022
·
IF 9.136
Xin Yu,Xiaoqing Dang,Shijie Li,Yu Li,He Wang,Kairui Jing,Haoyun Dong,Xia Liu
Metal-support interaction has a substantial influence on catalyst activity while little attention has been paid to it in the plasma catalytic system. Herein, the effect of support on the activity of CoMnO X -based catalysts was investigated for trichloroethylene removal by plasma catalysis, and CoMnO X /ZSM-5 exhibited the highest mineralization rate (36.93−94.24 %), HCl and Cl 2 yield (19.66−94.37 %), energy yield (63.29–29 g/kWh), as well as the lowest export ozone concentration (18.72–108.83 mg/m 3 ) under 6–10 kV. The excellent catalytic activity of CoMnO X /ZSM-5 was ascribed to the formation of abundant defects and oxygen vacancies , which was induced by the Si O Co/Mn hybridization promoting Co/Mn O bonds cleavage. CoMnO X /ZSM-5 also exhibited superior adsorption ability, large amount of Co 3+ , Mn 4+ and adsorbed oxygen species, high reducibility and suitable acidity. Moreover, CoMnO X /ZSM-5 maintained superior water-resistant ability and high catalytic activity after 50 h operation. The proposed TCE degradation mechanism suggested that the contribution of plasma active oxygen species was involved in TCE oxidation and oxygen cycle of catalyst. This work provides a novel strategy to design catalysts in plasma catalytic system.
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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2019
·Vol. 35
·期 3
·403-409
·
IF 1.071
Zhou Jie,Wu Shaojie,Zhang Wenhui,Liu Qing,Yang Bin,Ren Yinghui,Ma Haixia,Zhao Fengqi,Hu Rongzu
Three energetic ion salts of 3,6-bis[(1 H -1,2,3,4-tetrazol-5-yl)-amino]-1,2,4,5-tetrazine(BTATz), namely, methylamine salt(compound 1 ), ethylenediamine salt(compound 2 ), and diethylamine salt(compound 3 ), were synthesized and characterized by elemental analysis, Fourier transform infrared spectrometry, 1 H NMR spectroscopy, and 13 C NMR spectroscopy. The crystal structure of compound 1 was determined by single-crystal X-ray crystallography, and structural analysis revealed that it belonged to the monoclinic system with P 2 1 /c space group. In addition, the thermal behavior of the three compounds was studied by differential scanning calorimetry and thermogravimetry techniques. The thermal decomposition peak temperatures of the compounds were 574.89, 545.60, and 606.72 K, indicating that the three ion salts exhibited good thermal stability. The kinetic mechanism equations of the main decomposition process and the entropy of activation(Δ S ≠ ), enthalpy of activation(Δ H ≠ ), and Gibbs free energy of activation(Δ G ≠ ) of the three compounds were also obtained. Moreover, the thermal safety of the compounds was evaluated by the values of the self-accelerated decomposition temperature( T SADT ), thermal ignition temperature( T TIT ), and critical temperature of thermal explosion( T b ). The results showed that all the compounds demonstrated good thermal safety, and the thermal safety of compound 3 was better than that of the others.
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Marine Drugs
·
2026
·Vol. 24
·期 11
·378
·
IF 5.7
A-Long Zhang,Yan-Qing Guo,Zheng-Biao Zou,Xian-Wen Yang,Chun-Lan Xie
Chemical investigation of the deep-sea-derived fungusPenicillium maliMCCC 3A00140 afforded two new compounds, penimeroandranoid E (1) and malistatin (2), together with 16 known ones (3–18). Their structures were established by extensive spectroscopic analyses, including 1D and 2D NMR and HRESIMS. The relative configuration of1was supported by single-crystal X-ray diffraction, and its absolute configuration was assigned by comparison of the experimental and calculated electronic circular dichroism (ECD) spectra. Compound1was the meroterpenoid reported to possess a 6/6/6/5 spirocyclic framework—a spiro-fused variant of the 6/6/6/5 carbocyclic system that was characteristic of andrastin-type DMOA-derived meroterpenoids—and its structure and relative configuration were established by single-crystal X-ray diffraction. The stereochemical assignment of2was based on NOESY correlations and biosynthetic analogy with related statins. Screening of all isolates at 20 μM in a receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis model using primary murine bone marrow-derived macrophages identified1as the bioactive secondary metabolite. Compound1reduced the formation of tartrate-resistant acid phosphatase-positive multinucleated osteoclasts at 12.5–50 μM without decreasing cell viability after 48 h at concentrations up to 50 μM. These findings expand the chemical diversity of fungal meroterpenoids and identify1as a structurally distinctive anti-osteoclastogenic metabolite warranting further mechanistic investigation.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2021
·Vol. 32
·期 22
·26905-26916
·
IF 2.478
Yao Tiantian,Zou Hao,Zhang Jin,Zhou Yi
Constructing a heterojunction to extend the survival time of photogenerated carriers is an effective way to increase the photocatalytic performance of materials. The 2D-2D flower-like DUT-5@Bi 2 WO 6 composite material is obtained via the hydrothermal method for the frist time. The efficiency of Rhodamine B removal based on 30% DUT-5@Bi 2 WO 6 is 87% under visible light for 18 min, which is 4.55 times that of pure Bi 2 WO 6 . RhB-sensitized effect plays a decisive role in enhancing the photocatalytic activity of DUT-5 to RhB under visible light. The results shows that the type I heterojunction is formed between RhB/DUT-5 and Bi 2 WO 6 . The wide contact surface stems from heterojunction can accelerate the separation and transfer of photo-generated charges. Furthermore, the high specific surface area and unique pore structure of DUT-5 provide sufficient active sites for photocatalytic reactions. Thus, the efficient charge transfer and sufficient active sites contribute to the photocatalytic activity. This work provides a new idea for the development of 2D-2D composite materials to degrade organic pollutants under visible light to solve environmental pollution.
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ANALYTICAL CHEMISTRY
·
2025
·
IF 6.7
Yuxin Peng,Fenghui Zhu,Huan Wei,Jiping Ni,Xin Yang,Yichun Yao,Ying Jiang
5-Hydroxyindoleacetic acid (5-HIAA), a vital metabolite of serotonin (5-HT), is crucial for understanding metabolic pathways and is implicated in various mental disorders. In situ monitoring of 5-HIAA is challenging due to the lack of affinity ligands and issues with electrochemical fouling. We present an advanced sensing approach that integrates customizable molecular imprinting polymer (MIP) with self-driven galvanic redox potentiometry (GRP) for precise, real-time in vivo monitoring of 5-HIAA. The sensor, featuring pyrrole as the functional monomer in the MIP on the micrometer-sized bipolar carbon fiber electrodes, exhibited nanomolar sensitivity and superior selectivity for 5-HIAA over biosynthetic pathway analogs like 5-hydroxytryptophan (5-HTP) and serotonin. The MIPGRP sensor demonstrated excellent reversibility and resistance to fouling, enabling continuous monitoring in live guinea pig brains. We observed that intraperitoneal 5-HTP injection increases brain 5-HIAA levels, which is amplified up to 8-fold with Carbidopa pretreatment, providing deeper insights into the serotonergic signaling pathway. This work underscores the MIPGRP sensor’s potential as a versatile and reliable tool for advancing neuroscience research.
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ACS Sustainable Chemistry & Engineering
·
2025
·
IF 7.3
Xiang Chen,Hao Li,Yichao Lu,Zhichun Liu,Zhongsen Ma,Yajie Zhang
2,5-Furandicarboxylic acid (FDCA) has been extensively verified as a biobased aromatic ring platform compound. The development of mild and efficient novel oxidation technologies is important for FDCA preparation technologies. In this study, the efficient oxidation of 5-hydroxymethylfurfural (HMF) to produce FDCA by the TEMPO/NaClO/KBr single-phase aqueous catalytic oxidation system was systematically investigated, and the mechanism was analyzed in detail. Under the optimal reaction conditions, TEMPO as the main catalyst directly catalyzed the oxidation of HMF to FDCA, and the HMF conversion and FDCA yield both reached 100%. The oxidant NaClO could achieve a quantitative reaction (NaClO/HMF = 3:1(mol)). In addition, the reaction was conducted at mild room temperature and innovatively utilized a single aqueous system as the reaction solvent. This establishes a new method for the oxidative preparation of FDCA with the potential for technical scale-up.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Xin Zhou,Mingyang Ma,Ruhan Zhang,Xinru Song,Wenjie Li,Jiachen Jiang,Junlin Xie,Xiaoqiang Li,Li Cai,Xueqin Sun,Pijun Gong
This paper introduces a novel approach of encapsulating Pt nanoparticles within the pores of a molecular sieve. By comparing the dispersion, reducibility and surface acid sites, the effect of the combination of molecular sieves and Pt particles on the catalytic performance of toluene was studied. The findings demonstrate that Pt nanoparticles were encapsulated within the molecular sieve framework of ZSM-5 molecular sieves using an in-situ synthesis method, exhibiting remarkable catalytic activity towards toluene oxidation (T 90 =172 ℃). Mainly due to the spatial confinement of the ZSM-5 molecular sieve framework reduces the size of Pt nanoparticles, enhances their dispersion of the Pt@ZSM-5 catalysts. In addition, the space separation effect of ZSM-5 on Pt metal enhances their interaction and promotes the valence state conversion of Pt species. It leads to a large number of acid sites and oxygen vacancies in the catalyst, which improves the adsorption and migration of toluene, thereby improving the catalytic activity. This study will provide valuable insights into the preparation of new nanocatalysts and the catalytic treatment of toluene.
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Pharmaceuticals
·
2025
·Vol. 18
·期 3
·426
·
IF 4.8
Zhimin Song,Meijing Li,Ziwei Zhou,Xiaomeng Guo,Qi Wang,Zekuan Zhang,Keshu Wang,Qixiang Zheng,Wenjing Gou,Sha Wu,Hui Zhao,Muxin Gong
Background:Chronic migraine (CM) is a common complex nervous system disease, often accompanied by symptoms of the digestive tract that interact with each other, leading to prolonged and difficult-to-cure migraines. These symptoms are associated with abnormalities in 5-HT and its receptors. Wuzhuyu decoction (WZYD) is a traditional Chinese medicine prescription commonly used in clinics to treat CM; it relieves gastrointestinal symptoms, such as nausea and vomiting; however, its mechanism is still unclear. Investigating the differences in the role of WZYD compared to existing drugs targeting 5-HT receptors in the treatment of CM not only helps elucidate its pathogenesis but also provides possibilities for the development of new therapeutic approaches.Methods:An inflammation soup (IS)-induced CM male rat model was established. Based on a preliminary experiment, the target of WZYD in treating CM was determined by network pharmacology, and verified by molecular docking. ELISA, immunofluorescence, western blot, and real-time quantitative polymerase chain reaction (RT-qPCR) were used to evaluate the expression levels of CM-related indicators (5-HT, calcitonin gene-related peptide (CGRP), and c-Fos) to ensure the successful establishment of the CM model and the effectiveness of the drug. On this basis, the protein expression levels of 5-HT1A/3A receptors and their cAMP-response element binding protein (CREB) signaling pathway were detected by western blot and immunohistochemistry. The role of 5-HT1A/3A receptors in the treatment of CM by WZYD was validated using a 5-HT1A receptor antagonist (WAY 100635) and a 5-HT3A receptor agonist (SR 57227).Results:The results showed that WZYD increased the expression of 5-HT in the brain, decreased the expression of CGRP, c-Fos, ionized calcium-binding adapter molecule 1 (Iba1), and relieved CM. At the same time, WZYD also increased the expression of the 5-HT1A receptor and decreased the expression of the 5-HT3A receptor in the brain and colon of CM rats. Subsequently, WZYD further exerted its brain-gut integrated therapeutic effects by regulating the CREB signaling pathway mediated by 5-HT1A/3A receptors in the brain and colon of CM rats.Conclusions:WZYD not only regulates neurotransmitters in the brain and colon at the same time, but also specifically regulates 5-HT1A/3A receptors in the brain and colon, which explains the characteristics and advantages of WZYD from a new perspective. While effectively relieving headache symptoms, it also improves related gastrointestinal symptoms, which is more conducive to the treatment of CM.
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Food Packaging and Shelf Life
·
2025
·
IF 10.6
Huajian Ou,Lu Chen,Qiaohui Zeng,Wangsheng Qiu,Zihao Lin,Konglong Feng,Guang Liu,Ping Qi,Weijuan Huang,Jing Jing Wang
A novel photodynamic inactivation (PDI)-mediated antimicrobial packaging film (APF) was successfully fabricated by covalently grafting 5-aminolevulinic acid (ALA) onto the surface of TEMPO-oxidized chitin film (O-CT). The O-CT/ALA films exhibited good mechanical strength, remarkable UV-blocking capacity, high thermal stability, and chemical stability. Notably, the grafted ALA induced the generation of endogenous protoporphyrin IX in bacterial cells, and they were excited to produce ROS under the irradiation of blue light. Consequently, the films inactivated > 7.00 log CFU/mL of Vibrio parahaemolyticus and 3.29 log CFU/mL of Staphylococcus aureus , as well as efficiently eradicated the bacterial biofilms by disrupting their architectural structures. More importantly, the films inhibited the growth of native bacteria in salmon during storage at 4 °C and 25 °C. Therefore, the PDI-mediated APF is valid in inactivating bacteria and ensuring food quality in the food industry.
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ENERGY
·
2025
·
IF 9.4
Xin Li,Jie Zhu,Shengli Niu,Yue Zheng,Yang Xu
Biodiesel, known for its low carbon emissions and renewability, offers a promising alternative to fossil diesel. Support loading and additive modification are effective strategies for synthesizing high-performance heterogeneous catalysts. This study modified ZSM-5 zeolite with the addition of divalent barium ions and tetravalent cerium ions to develop the novel acid-base dual-activity Ba-Ce/ZSM-5 catalyst for biodiesel production from the acidified palm oil through transesterification. Characterization results show that the synergistic loading of the divalent barium ions and the tetravalent cerium ions generates snowflake-like particles on the multi-porous ZSM-5 surface and increases the density of catalytic active sites. Compared to the pure ZSM-5, the Ba40-Ce15/ZSM-5 catalyst exhibits nearly a five-fold increase in average pore size and forms the hierarchical pore structure. This modification reduces the diffusion resistance of triglycerides during transesterification. The catalyst retains excellent activity even in the presence of 5.00 wt% free fatty acids and moisture. With optimization by Response Surface Methodology with Box-Behnken Design (RSM-BBD), the maximum biodiesel yield of 97.48 % is achieved at the alcohol-to-oil molar ratio of 14.95 : 1, reaction temperature of 149.6 °C, catalyst amount of 6.73 wt%, and reaction duration of 2 h. Compared to previously reported catalysts, the Ba40-Ce15/ZSM-5 catalyst exhibits superior performance in increasing biodiesel yield while offering greater cost-effectiveness.
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EUROPEAN POLYMER JOURNAL
·
2024
·
IF 5.8
Chengfei Yue,Minjie Xu,Lizhen Zhong,Shuqi Tang,Guangming Cai,Ruquan Zhang,Bowen Cheng
pH-responsive materials have great potential for use in various advanced fields, such as microreactors and drug delivery. This work proposes a promising strategy for preparing composite aerogels with pH-responsive properties based on collagen (COL) and TEMPO-oxidized cellulose nanofibers (CNFs) through the self-assembly behavior of COL molecules for controlled-drug release. COL fibrils and carboxylated CNFs (cCNFs) exhibited a high-density, physical cross-linked supramolecular double network structure. Specifically, cyclodextrins (CDs) were introduced to optimize the structural stability and slow-release capability of the composite aerogels. Scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, and thermogravimetric analyses were used to characterize the structure of the aerogels, and the swelling behavior and water contact angle of the aerogels were evaluated. Using 5-fluorouracil (5-FU) as the model drug, the slow-release mechanism was subsequently revealed. Compared with the COL aerogels and COL/cCNF composite aerogels, the COL/cCNF@CD composite aerogels exhibited enhanced structural stability and slow-release performance through the synergistic enhancement effect of cCNFs and CDs. The aerogels also exhibited sensitivity to pH for regulating 5-FU release, and the COL composite aerogels with CDs and cCNFs maintained excellent cytocompatibility. In conclusion, CDs had a positive effect on the structural stability and pH-responsiveness of the composite aerogels and promoted the possible utilization of aerogels in drug delivery systems.
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MACROMOLECULAR BIOSCIENCE
·
2024
·
IF 4.4
Siyuan Yu,Xian Shao,Tong Wu,Zheng Liu,Pei Yu,Jinfeng Xing
In order to achieve long-term and controllable release of anti-tumor drugs at specific sites, temperature/pH responsive nanoparticles encapsulating 5-fluorouracil and methotrexate in situ are prepared through dispersion photopolymerization under green LED irradiation. The physicochemical properties of nanoparticles are characterized by scanning electron microscopy, Fourier transform infrared, dynamic light scattering, thermogravimetric/differential scanning calorimetry, and X-ray diffraction. In vitro drug release at different temperatures and pH values is examined to ascertain the release pattern of two drugs, which can be well described by Korsmeyer–Peppas kinetic model. The cytotoxicity evaluation illustrates that the tumor cells could be more effectively killed by the drug-loaded nanoparticles, and the improved therapeutic effect is attributed to the controllable and sustainable drug release as well as the enhanced cellular uptake. The blood safety and good biocompatibility of nanoparticles are further confirmed by hemolysis assay, indicating the prepared nanoparticles are potential candidates for effective tumor treatment.
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