DRUG DELIVERY
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2019
·
IF 3.829
Minchao Liu,Xiangyu Sun,Zhihui Liao,Yahui Li,Xiaoliang Qi,Yuna Qian,Hicham Fenniri,Ping Zhao,Jianliang Shen
Multifunctional core-shell nanocarriers based on zinc oxide (ZnO)-gated magnetic mesoporous silica nanoparticles (MMSN) were prepared for cancer treatment through magnetic targeting and pH-triggered controlled drug release. Under an external magnetic field, the MMSN could actively deliver chemotherapeutic agent, daunomycin (DNM), to the targeted sites. At neutral aqueous, the functionalized MMSN could stably accommodate the DNM molecules since the mesopores were capped by the ZnO gatekeepers. In contrast, at the acid intercellular environment, the gatekeepers would be removed to control the release of drugs due to the dissolution of ZnO. Meanwhile, ZnO quantum dots not only rapidly dissolve in an acidic condition of cancer cells but also enhance the anti-cancer effect of Zn2+. An in vitro controlled release proliferation indicated that the acid sensitive ZnO gatekeepers showed well response by the ‘on-off’ switch of the pores. Cellular experiments against cervical cancer cell (HeLa cells) further showed that functionalized MMSN significantly suppressed cancer cells growth through synergistic effects between the chemotherapy and Zn2+ ions with monitoring the treatment process. These results suggested that the ZnO-gated MMSN platform is a promising approach to serve as a pH-sensitive system for chemotherapies delivery and Zn2+ controlled release for further application in the treatment of various cancers by synergistic effects.
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ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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2019
·
IF 4.527
Yulin Xiang,Furen Kang,Yuxiu Xiang,Yurong Jiao
The synthesis of a humic acid-layered double hydroxide (HA-LDH) hybrid was purposed for the remediation of contaminated soils in mining area. The hybrid was characterized by X-ray diffraction, Fourier transform infrared spectroscopy , Scanning electron microscope and energy dispersive spectrometer. In order to investigate the effect of HA-LDH on the mine soil, greenhouse experiments of Artemisia ordosica were carried out under different concentrations of amendments (0, 1%, 3%, 5%, 7%). The plant growth, metal availability, and soil enzyme activities were studied to determine the effects of HA-LDH. The mine soil with 5% HA-LDH was the optimum proportion, and the growth of Artemisia ordosica was in good status. The HA-LDH and Artemisia ordosica could effectively decrease the bioavailability of heavy metals (such as Pb, Cr, Ni, Cd, Zn, and As) in the mine soil, and improve the enzyme activities of β-glucosidase, urease, and phosphatase . The HA-LDH with magnetism could be easily separated. The characteristics and reusability of HA-LDH could be well maintained after five cycles of remediation. Consequently, the HA-LDH is promising for the remediation of contaminated soils in mining area.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2019
·
IF 6.361
Yahuan Wang,Chengyu Lin,Zhiwei Wang,Zhimin Chen,Jiafu Chen,Yong Chen,Shaohua Liu,Jianwei Fu
The development of novel adsorbents with high adsorption capacity and easy recovery property is imperative in the field of wastewater treatment . In this study, a hard template-induced assembly strategy was developed to fabricate the magnetic hollow poly(cyclotriphosphazene- co -4,4′-sulfonyldiphenol)-Fe 3 O 4 (PZS-Fe 3 O 4 ) hybrid nanocapsules , in which Fe 3 O 4 nanoparticles were well embedded in the cross-linked PZS shell. The resulting samples were well characterized using SEM, TEM , EDS , FT-IR, VSM , XPS , XRD and N 2 sorption . Then, using Safranine T (ST) as model dye, the adsorption behavior of as-prepared hollow PZS-Fe 3 O 4 nanocapsules including adsorption kinetics , adsorption isotherms , adsorption mechanism, and recyclability were systematically evaluated and discussed. The results revealed that the magnetic hollow PZS-Fe 3 O 4 nanocapsules own high adsorption capacity towards ST dye and outstanding magnetic separation functionality. The pseudo-second-order kinetic model and the Langmuir model can well describe the experimental data, and the adsorption process is controlled by more than one diffusion step. The interaction between ST dye and hollow PZS-Fe 3 O 4 nanocapsules is ascribed to π-π interaction and electrostatic interaction. The thermodynamic parameters demonstrated that the adsorption processes were physical, endothermic, and spontaneous. Additionally, the magnetic hollow PZS-Fe 3 O 4 nanocapsules also shows excellent peroxidase-like catalytic activity in the oxidation of 3,3′,5,5′-tetramethylbenzidine with H 2 O 2 , indirectly confirming the adsorption kinetic results.
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RSC Advances
·
2018
·Vol. 8
·期 31
·17489-17496
·
IF 2.936
Xiaodong Sun,Mingxu Sui,Guangzhen Cui,Ling Li,Xiaopeng Li,Xuliang Lv,Fan Wu,Guangxin Gu
Electromagnetic irradiation has caused environmental pollution and harmful effects on human health. The use of effective materials to attenuate electromagnetic energy is urgently required. In this study, Fe3O4 nanoparticles (NPs) decorated on a CuS platelet-based sphere (CuS/Fe3O4) with popcorn chicken-like micromorphology were synthesized through a solvothermal deposition method. The effects of reaction temperature and quantity of Fe3O4 NPs on the heterostructures, morphologies and electromagnetic absorption (EA) properties of the heterostructures were investigated. CuS/Fe3O4 heterostructures exhibited remarkable enhancement in comparison with pure Fe3O4 NPs and the CuS platelet-based sphere. With the contribution from dielectric and magnetic losses, a CuS/Fe3O4 heterostructure-loaded composite could achieve a minimum reflection loss (RL) of −61.32 dB at 14.00 GHz and an effective EA bandwidth (≤−10 dB) of 4.15 GHz at a thickness of only 1.5 mm simultaneously. The current study indicates that the CuS/Fe3O4 heterostructures can potentially be applied as advanced electromagnetic absorbers.
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Materials
·
2018
·Vol. 11
·期 5
·780
·
IF 2.467
Xiaodong Sun,Guangyan Ma,Xuliang Lv,Mingxu Sui,Huabing Li,Fan Wu,Jijun Wang
In this study, Fe3O4/ZnO core–shell nanocomposites were synthesized through a chemical method of coating the magnetic core (Fe3O4) with ZnO by co-precipitation of Fe3O4with zinc acetate in a basic medium of ammonium hydroxide. The phase structure, morphology and electromagnetic parameters of the Fe3O4/ZnO core–shell nanocomposites were investigated. The results indicated that the concentration of the solvent was responsible for controlling the morphology of the composites, which further influenced their impedance matching and microwave absorption properties. Moreover, Fe3O4/ZnO nanocomposites exhibited an enhanced absorption capacity in comparison with the naked Fe3O4nanospheres. Specifically, the minimum reflection loss value reached −50.79 dB at 4.38 GHz when the thickness was 4.5 mm. It is expected that the Fe3O4/ZnO core–shell structured nanocomposites could be a promising candidate as high-performance microwave absorbers.Keywords:core–shell structure;electromagnetic absorption;interfacial polarization;Fe3O4;ZnO
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APPLIED ORGANOMETALLIC CHEMISTRY
·
2018
·Vol. 32
·期 12
·e4534
·
IF 3.581
Mingliang Ma,Yuying Yang,Renjun Feng,Li Jia,Guopeng Chen,Wenting Li,Ping Lyu
A highly effective and stable hollow Fe 3 O 4 /P(GMA-EGDMA)-SO 3 H/Au-PPy catalyst was prepared. Monodisperse hollow Fe 3 O 4 microspheres were synthesized using a hydrothermal method. As the catalyst support, magnetic hollow Fe 3 O 4 /P(GMA-EGDMA) microspheres with core–shell structure were prepared by distillation precipitation polymerization. Then sulfonic acid groups (─SO 3 H) were introduced into the surface of the support by surface modification. Au 3+ could be adsorbed by coordination with ─SO 3 H and underwent redox reactions with added pyrrole monomers. Finally, an Au–polypyrrole (PPy) layer was formed on the surface of the Fe 3 O 4 /P(GMA-EGDMA)-SO 3 H microspheres. The synthesized material was characterized using various techniques. Results indicated that the as-prepared hollow Fe 3 O 4 /P(GMA-EGDMA)-SO 3 H/Au-PPy catalyst had excellent catalytic activity and exhibited reusability for the reduction reaction of 4-nitrophenol. In addition, the catalyst was reusable for at least ten successive cycles.
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APPLIED ORGANOMETALLIC CHEMISTRY
·
2018
·Vol. 32
·期 8
·e4428
·
IF 3.581
Songfang Zhao,Haobo Jiang,Jinhui Li,Xiangying Meng,Tianyu Chao,Zhe Zhang,Peng Zhang,Yongju Gao,Duxia Cao
Efficient and reusable nanocatalysts fabricated via a facile assembly are highly desirable for the cost-effective hydrogenation reduction. Inspired by a fishing process with a fishnet, multifunctional nanostructured catalysts are rationally designed to combine interesting features via the self-redox assembly of Fe 3 O 4 -Ag composites on reduced graphene oxide (rGO) (Fe 3 O 4 -Ag/rGO). In detail, Fe 3 O 4 nanoparticles (NPs) endow the ternary hybrids with superparamagnetism (21.42 emu g −1 ), facilitating catalysts to be separated from the reaction system. rGO could provide electron transfer pathways, enhancing catalytic activity. More interestingly, GO and Ag + could behave as oxidants to oxidize Fe 2+ for the in situ assembly of Fe 3 O 4 -Ag/rGO without any addition of reductant/oxidant or organic solvents, and AgNPs endow the ternary hybrids with excellent catalytic behaviour. Meaningfully, the bioinspired process enables the ternary hybrids to possess more abundant micro−/nanopores, larger surface area, and more amorphization. They exhibit exceptional catalytic performance, and could be recycled with excellent activity by means of convenient magnetic separation (at least 7 times). Moreover, the ternary hybrids could degrade methylene blue under UV light due to different valence states of Fe in Fe 3 O 4 . Therefore, the proposed bioinspired assembly and structure design for hierarchical catalysts would pave a promising way to assemble other catalysts.
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SCIENCE OF THE TOTAL ENVIRONMENT
·
2018
·
IF 4.61
Tao Zeng,Shuqi Li,Jianan Hua,Zhiqiao He,Xiaole Zhang,Hongru Feng,Shuang Song
Nanocarbon materials are emerging as alternative activators of peroxymonosulfate (PMS) for organics decomposition. However, the relatively low activity and complex syntheses hindered their practical application and innovation with respect to rational design of carbocatalysts is highly desired. Herein, an in situ replication and transformation strategy was employed to facilely convert porous Fe 3 O 4 microspheres into novel Fe/N codoped large-pore mesoporous carbon spheres (M‑Fe/NC) as Fenton-like catalysts for PMS activation . Benefiting from the abundance of active sites induced by dual heteroatom doping, the enhanced active site exposure due to the unique mesoporous structure, and the high stability of carbon component, the derived M‑Fe/NC was superior to the pristine Fe 3 O 4 for PMS activation to degrade various organics and was efficient over a wide pH range (2–9). Compared with the proposed mechanisms of previous reports, both radical (surface-bound SO 4 − and OH) and nonradical ( 1 O 2 and direct oxidation) pathways are involved in the M‑Fe/NC/PMS system. Furthermore, experimental observations in combination with DFT calculations reveal that graphitic N and Fe N 4 sites serve as dual reaction centers in the catalysis. This research opened an avenue for development of novel multi-doped carbocatalysts used to activate PMS for sustainable remediation.
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JOURNAL OF HAZARDOUS MATERIALS
·
2015
·
IF 4.529
Chao Shan,Zhiyao Ma,Meiping Tong
Poly(1-vinylimidazole)-grafted Fe 3 O 4 @SiO 2 magnetic nanoparticles (FSPV) were developed to remove both free Cd(II) and nitrilotriacetic acid (NTA) complexed Cd(II) from water. The adsorption capacity of NTA-complexed Cd(II) (42.1 mg/g) was larger than that of free Cd(II) (24.8 mg/g). Free Cd(II) and NTA-complexed Cd(II) could be reduced from 50 μg/L to below 5 μg/L within 10 and 20 min, respectively. FSPV could effectively remove trace free and NTA-complexed Cd(II) over broad pH ranges of 5–10 and 5–11, respectively. Moreover, the presence of seven coexisting ions (up to 100 mM) including four cations (Na + , K + , Ca 2+ , and Mg 2+ ) and three anions (Cl − , NO 3 − , and SO 4 2− ) all slightly promoted the removal of both free and NTA-complexed Cd(II) onto FSPV. The removal of free Cd(II) or NTA-complexed Cd(II) was not obviously affected by the presence of Ni(II) and Co(II) (50 μg/L), humic acid (up to 3 mg/L as TOC) or alginate (up to 8 mg/L as TOC). In addition, FSPV could be regenerated with 10 mM HCl in 10 min, and the removal of both types of Cd(II) maintained above 95% in five consecutive adsorption/regeneration cycles. Therefore, FSPV could be utilized as promising adsorbent for both free and NTA-complexed Cd(II).
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ADVANCED FUNCTIONAL MATERIALS
·
2015
·Vol. 25
·期 22
·3341-3350
·
IF 11.805
Long Pan,Xiao-Dong Zhu,Xu-Ming Xie,Yi-Tao Liu
Today, the ever-increasing demand for large-size power tools has provoked worldwide competition in developing lithium-ion batteries having higher energy and power densities. In this context, advanced anode materials are being extensively pursued, among which TiO 2 is particularly promising owing to its high safety, excellent cost and environmental performances, and high cycle stability. However, TiO 2 is faced with two detrimental deficiencies, that is, extremely low theoretical capacity and conductivity. Herein, a smart hybridization strategy is proposed for the hierarchical co-assembly of TiO 2 nanorods and Fe 3 O 4 nanoparticles on pristine graphene nanosheets, aiming to simultaneously address the capacity and conductivity deficiencies of TiO 2 by coupling it with high-capacity (Fe 3 O 4 ) and high-conductivity (pristine graphene) components. The resulting novel, multifunctional ternary heterostructures effectively integrate the intriguing functionalities of the three building blocks: TiO 2 as the major active material can adequately retain such merits as high safety and cycle stability, Fe 3 O 4 as the auxiliary active material can contribute extraordinarily high capacities, and pristine graphene as the conductive dopant can guarantee sufficient percolation pathways. Benefiting from a remarkable synergy, the ternary heterostructures deliver superior reversible capacities and rate capabilities, thus casting new light on developing next-generation, high-performance anode materials.
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BIOSENSORS & BIOELECTRONICS
·
2015
·
IF 6.409
Na Li,Xia Hao,Bei Hua Kang,Zhen Xu,Yan Shi,Nian Bing Li,Hong Qun Luo
A novel, highly sensitive assay for quantitative determination of DNA is developed based on hybridization chain reaction (HCR) amplification and the separation via core–shell Fe 3 O 4 polydopamine nanoparticles (Fe 3 O 4 @PDA NPs). In this assay, two hairpin probes are designed, one of which is labeled with a 6-carboxyfluorescein (FAM). Without target DNA, auxiliary hairpin probes are stable in solution. However, when target DNA is present, the HCR between the two hairpins is triggered. The HCR products have sticky ends of 24 nt, which are much longer than the length of sticky ends of auxiliary hairpins (6 nt) and make the adsorption much easier by Fe 3 O 4 @PDA NPs. With the addition of Fe 3 O 4 @PDA NPs, HCR products could be adsorbed because of the strong interaction between their sticky ends and Fe 3 O 4 @PDA NPs. As a result, supernatant of the solution with target DNA emits weak fluorescence after separation by magnet, which is much lower than that of the blank solution. The detection limit of the proposed method is as low as 0.05 nM. And the sensing method exhibits high selectivity for the determination between perfectly complementary sequence and target with single base-pair mismatch. Importantly, the application of the sensor for DNA detection in human serum shows that the proposed method works well for biological samples.
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BIOSENSORS & BIOELECTRONICS
·
2015
·
IF 6.409
Taotao Feng,Xiuwen Qiao,Haining Wang,Zhao Sun,Chenglin Hong
A sandwich-type electrochemical immunosensor was developed for sensitive detection of carcinoembryonic antigen (CEA) by using ferroferric oxide@silica–amino groups (Fe 3 O 4 @SiO 2 –NH 2 ) as carriers and gold nanoparticles–graphene oxide (GO–AuNPs) as platform. The Fe 3 O 4 @SiO 2 –NH 2 surface was used as linked reagents for co-immobilization of ferrocenecarboxylic acid (Fc-COOH) and secondary anti-CEA (Ab 2 ) to prepare the signal probe , and it also could hasten the decomposition of hydrogen peroxide (H 2 O 2 ) to amplify signals. Differential pulse voltammetry (DPV) was successfully used to quantify CEA. Under the optimized conditions, the designed immunosensor shows an excellent analytical performance wide dynamic response range of CEA concentration from 0.001 ng mL −1 to 80 ng mL −1 with a relatively low detection limit of 0.0002 ng mL −1 ( S / N =3), and high specificity and good reproducibility. The proposed immunosensor was successfully used to determine CEA in spiked human serum samples.
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