JOURNAL OF SURFACTANTS AND DETERGENTS
·
2016
·Vol. 19
·期 4
·681-691
·
IF 1.853
Zhao Xiaohui,An Dong,Ye Zhiwen
Two groups of disymmetric Gemini imidazolium surfactants, [C 14 C 4 C
m
im]Br 2 ( m = 10, 12, 14) and [C
m
C 4 C
n
im]Br 2 ( m + n = 24, m = 12, 14, 16, 18) surfactants, were synthesized and their structures were confirmed by 1 H NMR and ESI–MS spectroscopy. Their adsorption at the air/water interface, thermodynamic parameters and aggregation behavior were explored by means of surface tension, electrical conductivity and steady-state fluorescence. A series of surface activity parameters, including cmc, γ
cmc , π
cmc , p C
20 , cmc/ C
20 , Γ
max and A
min , were obtained from surface tension measurements. The results revealed that the overall hydrophobic chain length ( N
c ) for [C 14 C 4 C
m
im]Br 2 and the disymmetry ( m/n ) for [C
m
C 4 C
n
im]Br 2 had a significant effect on the surface activity. The cmc values decreased with an increase of N
c or m/n . The thermodynamic parameters of micellization (Δ G
θ m
, Δ H
θ m
, Δ S
θ m
) derived from the electrical conductivity indicated that the micellization process of [C 14 C 4 C
m
im]Br 2 and [C
m
C 4 C
n
im]Br 2 was entropy-driven at different temperatures, but the contribution of Δ H
θ m
to Δ G
θ m
was enhanced by increasing N
c or m/n . The micropolarity and micellar aggregation number ( N
agg ) were estimated by steady-state fluorescence measurements. The results showed that the surfactant with higher N
c or m/n can form larger micelles, due to a tighter micellar structure.
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Nanoscale Research Letters
·
2018
·Vol. 13
·期 1
·1-10
·
IF 3.125
Zhang Shiyu,Zhang Chao,Liu Mingyue,Huang Renliang,Su Rongxin,Qi Wei,He Zhimin
Nanoscale zero-valent iron (nZVI) has shown considerable promise in the treatment of chlorinated organic compounds, but rapid aggregation and inactivation hinder its application. In this study, palladium-doped zero-valent iron nanoparticles involving poly (γ-glutamic acid) (Fe-Pd@PGA NPs) were synthesized. The nanoparticles were small (~100 nm), uniformly distributed, and highly stable. The dechlorination performance of Fe-Pd@PGA NPs was evaluated using p -CP as a model. The results demonstrated that Fe-Pd@PGA NPs show high activity even in weakly alkaline conditions. The maximum rate constant reached 0.331 min − 1 at pH 9.0 with a Fe to p -CP ratio of 100. Additionally, the dechlorination activity of Fe-Pd@PGA NPs is more than ten times higher than that of the bare Fe-Pd NPs, demonstrating the crucial role of PGA in this system. Furthermore, we investigated the dechlorination performance in the presence of different anions. The results indicated that Fe-Pd@PGA NPs can maintain high activity in the presence of Cl − , H 2 PO 4 − , and humic acid, while HPO 4 2− and HCO 3 − ions slightly reduce the dechlorination activity. We believed that PGA is a promising stabilizer and promoter for Fe-Pd NPs and the Fe-Pd@PGA NPs have the potential for practical applications.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
·
2018
·Vol. 29
·期 8
·1-14
·
IF 2.448
Liu Chundong,Wang Jianhua,Huang Sheng,Yu Lin,Wang Yan,Chen Hang,Wang Dong
Peptide nucleic acid (PNA) holds enormous potentials as antisense/antigenic drug due to its specific binding ability and biostability with DNA or RNA. However, the poor cellular delivery is the key obstacle in development of PNA therapy. To overcome this difficulty, we developed self-assembled nanoparticles (NPs) for delivery of PNA to living cells using amphiphilic CS derivatives. A series of N,N,N-trimethyl-O-alkyl chitosans (TMACs) with different lengths of alkyl chains were synthesized. The structures of these synthesized chemicals were characterized with FT-IR and 1 H NMR. We found that the TMACs were all able to self-assemble in aqueous condition to form nano-size NPs. These nano-size NPs are spherical shape with a size range of around 100 nm and a zeta potential above +30 mV. PNA was easily encapsulated into chitosan derivative NPs by an ultrasonic method with entrapment efficiency up to 75%. The PNA-loaded TMAC NPs released the drug in a sustained manner in PBS (pH 7.4) at 37 °C. N,N,N-trimethyl-O-cetyl chitosan (TMCC) showed the best in vitro hemocompatibility and cell viability. These TMCC based NPs were able to dramatically increase the cellular uptake of PNA, specifically, 66-fold higher compared to without using these nanoparticles. The results suggest that the designed TMCC NPs might be a promising solution for improving cellular delivery of PNA.
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BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
·
2018
·Vol. 101
·期 4
·536-542
·
IF 1.48
Qian Haifeng,Ke Mingjing,Qu Qian,Li Xingxing,Du Benben,Lu Tao,Sun Liwei,Pan Xiangliang
The manufacturers of single-walled carbon nanotubes (SWCNTs) are continuously expanding their manufacturing and commercial markets, indicating that the environmental release and accumulation of SWCNTs in soil is inevitable. However, little is known about the effects of SWCNTs on soil physicochemical properties and soil microbial communities. Our results showed that treatment with SWCNTs resulted in an enhancement of microorganism metabolism related to soil organic compound degradation and a change in the structure of soil microbial communities, but the diversity of soil microorganisms was not significantly affected. The decrease in soil urease activity and the increase in the relative abundance of Nitrospirae after SWCNTs exposure might be relevant to the induction of soil nitrification. The relative abundances of phosphate-solubilizing microorganisms increased after exposure to SWCNTs, which was beneficial for phosphorus bioavailability in the soil. Our current study highlights that exposure to SWCNTs at concentrations of 3 and 10 µg/g can change the composition of soil microorganism communities, promote soil organic degradation and improve soil fertility by enhancing N and P availability in a short time.
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CELL DEATH AND DIFFERENTIATION
·
2023
·
IF 12.4
Xu Ya-Jie,Dai Shang-Kun,Duan Chun-Hui,Zhang Zi-Han,Liu Pei-Pei,Liu Cong,Du Hong-Zhen,Lu Xu-Kun,Hu Shijun,Li Lei,Teng Zhao-Qian,Liu Chang-Mei
The ability of neural stem/progenitor cells (NSPCs) to proliferate and differentiate is required through different stages of neurogenesis. Disturbance in the regulation of neurogenesis causes many neurological diseases, such as intellectual disability, autism, and schizophrenia. However, the intrinsic mechanisms of this regulation in neurogenesis remain poorly understood. Here, we report that Ash2l (Absent, small or homeotic discs-like 2), one core component of a multimeric histone methyltransferase complex, is essential for NSPC fate determination during postnatal neurogenesis. Deletion of Ash2l in NSPCs impairs their capacity for proliferation and differentiation, leading to simplified dendritic arbors in adult-born hippocampal neurons and deficits in cognitive abilities. RNA sequencing data reveal that Ash2l primarily regulates cell fate specification and neuron commitment. Furthermore, we identified Onecut2 , a major downstream target of ASH2L characterized by bivalent histone modifications, and demonstrated that constitutive expression of Onecut2 restores defective proliferation and differentiation of NSPCs in adult Ash2l -deficient mice. Importantly, we identified that Onecut2 modulates TGF-β signaling in NSPCs and that treatment with a TGF-β inhibitor rectifies the phenotype of Ash2l -deficient NSPCs. Collectively, our findings reveal the ASH2L-Onecut2-TGF-β signaling axis that mediates postnatal neurogenesis to maintain proper forebrain function.
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CELLULOSE
·
2022
·Vol. 29
·期 3
·2077-2091
·
IF 6.123
Xu Jiangqi,Li Xia,Yu Wenjing,Wang Xing,Ma Jianzhong
There is an urgent need to develop novel antimicrobial cotton textiles (CT) because microbial contamination is one of the greatest threats to public health due to the emerging of infectious diseases and drug-resistant pathogens. In this work, an isocyanate group containing borneol-based antimicrobial finishing agent (NCO-B) was developed which can be covalently grafted to the surface of cotton textiles by a simple one-step method. The obtained NCO-B-finished CT (NCO-B-CT) exhibited broad-spectrum antimicrobial adhesion properties against bacteria ( E. coli ), including superbugs (MRSA), and fungi ( A. niger ). Due to its unique antimicrobial mechanism of borneol stereochemistry, the obtained NCO-B-CT is a non-releasing antimicrobial material which causes no skin sensitization and has no cytotoxicity. The mechanical properties of the CT were also improved after this finishing process. Additionally, it displayed durable washing fastness and antimicrobial adhesion properties by bearing 50 times laundering cycles. Therefore, this material may have great potential for application in multifunctional textiles, flexible skin electronics and medical protection. Graphical abstract
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2018
·Vol. 25
·期 18
·17310-17320
·
IF 2.8
Pu Shengyan,Xue Shengyang,Yang Zeng,Hou Yaqi,Zhu Rongxin,Chu Wei
A superparamagnetic graphene oxide (GO)/Fe 3 O 4 nanocomposite (MGO) was prepared by a facile in situ co-precipitation strategy, resulting in a prospective material for the application of graphene oxide in wastewater treatment. MGO was characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), x-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR). The prepared adsorbent showed a high adsorption efficiency relevant to the purification of dye-contaminated wastewater and could be readily magnetically separated. The maximum adsorption capacity was ca. 546.45 mg g −1 for the common cationic dye methylene blue (MB) and ca. 628.93 mg g −1 for the anionic dye Congo red (CR). The adsorption processes fit the pseudo-second-order kinetic model well, which revealed that these processes may involve the chemical interaction between adsorbate and adsorbent. The thermodynamic parameters indicated that the adsorption reaction was an endothermic and spontaneous process. Furthermore, the prepared magnetic adsorbent had a wide effective pH range from 5 to 11 and showed good stability after five reuse cycles. The synthetic MGO showed great potential as a promising adsorbent for organic contaminant removal in wastewater treatment.
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ADSORPTION-JOURNAL OF THE INTERNATIONAL ADSORPTION SOCIETY
·
2016
·Vol. 23
·期 1
·73-85
·
IF 1.87
Hu Hangbiao,Zhang Tao,Yuan Shaojun,Tang Shengwei
Abstract The adsorption performance of multi-walled carbon nanotubes (MWCNTs) towards CO 2 gas was enhanced by covalently grafting of phenylenediamine (PDA) via an activation-grafting process. Different loading amounts were achieved by changing the activation time and the dosage of activating agent. The so-synthesized adsorbents were characterized by Fourier transform infrared spectroscopy, X-ray diffraction, Thermogravimetry analysis, Transmission electron microscope, Raman spectroscopy and Nitrogen adsorption–desorption analysis. The CO 2 adsorption properties were studied via static volumetric method. The results indicated that the modification process did not alter the crystal structure, whilst the quantity of defect sites and amorphous structures increased greatly. Moreover, the average pore size after functionalization increased from 9.68 to 23.80 nm. 0.59 mmol·g −1 of CO 2 were captured by aminated MWCNTs at 303.15 K and 200 kPa, while the adsorption capacity of the raw materials was only 0.17 mmol·g −1 under the same conditions. Adsorption–regeneration cycles exhibited the stability of the PDA modified MWCNTs during the prolonged cyclic operations. We found that the adsorption of CO 2 on MWCNTs belonged to physical adsorption and the adsorption behavior of CO 2 on PDA modified MWCNTs was a chemical adsorption. The effective enhancement of the CO 2 capture ability was attributed to the increased number of active sites, which offered stronger interactions with CO 2 after PDA grafting.
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MICROCHIMICA ACTA
·
2021
·Vol. 188
·期 10
·1-10
·
IF 5.833
Li Min,Cai Yi-Na,Peng Chi-Fang,Wei Xin-Lin,Wang Zhou-Ping
Copper nanomaterials based on DNA scaffold (DNA-Cu NMs) are becoming a novel fluorescent material, but it is still challenging to obtain highly fluorescent DNA-Cu NMs with excellent stability. In this work, we report a kind of copper nano-assemblies (Cu NASs) with aggregation-induced emission enhancement (AIEE) property using DNA dendrimers with sticky end as template. The sticky end of the DNA dendrimers induced the formation of much bigger Cu NASs with average size ranging from 131 to 264 nm, depending on the length of the DNA dendrimer sticky end from 6 bases to 27 bases. Compared with complete complementary DNA dendrimer, nearly 6-fold fluorescence enhancement was achieved using DNA dendrimer with 27 bases sticky end. Moreover, the DNA dendrimer-Cu NASs demonstrated excellent stability in serum and could be rapidly quenched by Pb 2+ ions. Based on the above property, highly sensitive and selective fluorescent detection of Pb 2+ ions was possible with a linear range of 2.0–100 nM and a detection limit of 0.75 nM. Due to the sensitive and rapid response to Pb 2+ as well as excellent stability in complex matrix, the proposed fluorescent Cu NASs demonstrated high potential as an excellent fluorescent probe for Pb 2+ in complex matrix. Graphical abstract
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2019
·Vol. 411
·期 17
·3801-3810
·
IF 3.286
Huang Yuanlin,Liang Guangzhao,Lin Tianran,Hou Li,Ye Fanggui,Zhao Shulin
The convenience of colorimetric sensors is useful for practical applications. In this work, we constructed a novel colorimetric sensor with magnetic separation ability that can be operated in nearly neutral conditions and achieve one-step detection of metabolites. Magnetic Cu doped Fe 3 O 4 @FeOOH magnetic nanocomposite (Cu/Fe 3 O 4 @FeOOH) with an oxygen vacancy was prepared by a one-step self-assembly hydrothermal method, and fully characterized by different methods. The oxygen vacancy generated by the incorporation of Cu 2+ cations into the Fe 3 O 4 @FeOOH structure was confirmed to be a vital reactive site for enhancing the catalytic activity, which opens up a new way of designing highly efficient enzyme mimics. Benefiting from its inherent horseradish-peroxidase-like activity, a simple and selective enzyme-based colorimetric sensor was developed for one-step detection of H 2 O 2 and cholesterol, and 3,3′,5,5′-tetramethylbenzidine was catalyzed by H 2 O 2 to generate a colored product of oxidized 3,3′,5,5′-tetramethylbenzidine for signaling. H 2 O 2 and cholesterol can be linearly detected in the same range from 0.01 to 0.4 mmol L -1 with detection limits of 0.0075 mmol L -1 and 0.0082 mmol L -1 , respectively. The proposed colorimetric sensor has satisfactory reusability, accuracy, and practicability in human serum samples, indicating its potential application for the detection of different metabolites in the fields of life science and analytical science.
Graphical abstract
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Nature Communications
·
2021
·Vol. 12
·期 1
·1-14
·
IF 14.919
Wang Yuqin,Guan Xiaoyu,Zhang Shanyu,Liu Yao,Wang Sha,Fan Pingping,Du Xiaoyu,Yan Shuanghong,Zhang Panke,Chen Hong-Yuan,Li Wenfei,Zhang Daoqiang,Huang Shuo
Folding of RNA can produce elaborate tertiary structures, corresponding to their diverse roles in the regulation of biological activities. Direct observation of RNA structures at high resolution in their native form however remains a challenge. The large vestibule and the narrow constriction of a Mycobacterium smegmatis porin A (MspA) suggests a sensing mode called nanopore trapping/translocation, which clearly distinguishes between microRNA, small interfering RNA (siRNA), transfer RNA (tRNA) and 5 S ribosomal RNA (rRNA). To further profit from the acquired event characteristics, a custom machine learning algorithm is developed. Events from measurements with a mixture of RNA analytes can be automatically classified, reporting a general accuracy of ~93.4%. tRNAs, which possess a unique tertiary structure, report a highly distinguishable sensing feature, different from all other RNA types tested in this study. With this strategy, tRNAs from different sources are measured and a high structural conservation across different species is observed in single molecule.
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Food Analytical Methods
·
2020
·Vol. 13
·期 6
·1255-1261
·
IF 2.667
Wu Zhengzong,He Deyun,Cui Bo,Jin Zhengyu,Xu Enbo
Reliable and sensitive detection of Staphylococcal enterotoxin B (SEB) is important to prevent potential human health risk from foods contaminated by SEB. Here, a triple-channel assay was developed for ultrasensitive detection of SEB. Based on the optical characteristics of tetramers composed of gold nanoparticles (AuNPs) and upconversion nanoparticles (UCNPs), the SEB amounts in food products can be simultaneously detected by using surface-enhanced Raman scattering (SERS), fluorometry, and circular dichroism (CD). Under SERS mode, fluorescence mode, and CD mode, wide linear detection ranges (1–750 pg/mL, 1–750 pg/mL, and 2–500 pg·mL −1 ) were achieved. Furthermore, the practicality of the novel assay was evaluated by determining SEB contents in spiked milk samples. These results indicate that the triple-mode aptasensor is a potential useful tool in quantitative detection of SEB in foods.
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