CERAMICS INTERNATIONAL
·
2020
·
IF 3.83
Xiaoyu Zhu,Peng Liu,Ting Xue,Yu Ge,Shirong Ai,Yingying Sheng,Ruimei Wu,Lulu Xu,Kaijie Tang,Yangping Wen
A new bifunctional intelligent nanosensing platform based on graphene-like titanium carbide MXene (Ti 2 C MXene)/Au–Ag nanoshuttles (NSs) for both electrochemical and surface-enhanced Raman scattering (SERS) intelligent analysis of ultra-trace carbendazim (CBZ) residues in tea and rice coupled with machine learning (ML) was successfully designed. Ti 2 C MXene was synthesized by selectively etching Al layers of Ti 2 AlC with hydrofluoric acid and high-temperature calcination . Ti 2 C MXene/Au–Ag NSs prepared by the ultrasonic dispersion of graphene-like Ti 2 C MXene into Au–Ag NSs solution under dark conditions displayed large and rough surface, enhanced conductivity, excellent electrochemical response, prominent Raman enhancement, and high stability. The ML via different algorithms such as artificial neural network, support vector machine, and relevance vector machine (RVM) for the intelligent analysis of CBZ was contrasted and discussed. RVM displayed more superiority for the electrochemical analysis of CBZ in a wide linear range of 0.006 – 9.8 μM with low limit of detection (LOD) of 0.002 μM and SERS detection of CBZ in the wide linear range of 0.033 – 10 μM with low LOD of 0.01 μM. This will provide a new bifunctional intelligent sensing platform via different ML algorithms for improving accuracy of sensor via mutual verification of two or more methods of detection and a new bifunctional nanosensing platform based on the development of graphene-like nanohybrid for food and agro-products safety.
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高影响因子
FOOD CONTROL
·
2023
·
IF 6
Yangjie Chen,Li Zheng,Juan Hao,Lijuan Huang,Qinghui Wang,Youting Zhou,Zhihang Yin,Lingpu Jia,Huiming Li,Wenlong Liao,Kunping Liu
In this study, a magnetic metal-organic frameworks (MOFs) based hybrid substrate was designed and fabricated for SERS detection of enrofloxacin (ENR) in milk. The magnetic MOF (Fe 3 O 4 @UiO-66-NH 2 ) was synthesized by a facile microwave-assisted method, then loaded with popcorn-like Au nanoparticles (NPs) through electrostatic interaction. The as-prepared SERS substrate (Fe 3 O 4 @UiO-66-NH 2 /Au NPs) integrated the abundant hot spots of popcorn-like Au NPs with porous Fe 3 O 4 @UiO-66-NH 2 , which greatly improved its SERS activity and stability. More importantly, benefiting from the fingerprint characteristics of SERS and adsorption performance of Fe 3 O 4 @UiO-66-NH 2 , the SERS substrate exhibited high selectivity and sensitivity in detecting ENR. Under the optimal detection condition, a good linearity (R 2 = 0.996) was obtained with ENR concentration of 1.0 × 10 −9 –1.0 × 10 −6 M in spiked milk, the LOD was as low as 5.26 × 10 −10 M, and the recoveries were in the range of 76.1–86.1 % at three different spiking levels. The whole detection process including sample pretreatment took about 50 min, which indicating that the prepared substrate has great potential in sensitive and real-time detection of ENR in milk.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2023
·
IF 8.4
Xing Dai,Xiaohan Liu,Tao Xu,Chenjie Gu,Feiyu Zhao,Tao Jiang
Controlled aggregation of noble metal nanoparticles is incredibly crucial for obtaining reliable surface-enhanced Raman scattering (SERS) properties. Here, a rational agglomeration of large Ag nanowires (NWs) and small Ag nanocubes (NCs) was readily facilitated by simply utilizing the intrinsic viscosity of adhesive tape , leading to the generation of abundant electromagnetic “hotspots” around the numerous crossed nanotips and ultra-small nanogaps. After the molecular enrichment efficiency was further promoted by exploiting a hydrophilic-hydrophobic strategy, an ultra-low limit of detection as 8.8 × 10 −11 M was demonstrated for rhodamine 6 G. Benefiting from the high sensitivity of the SERS chip, its application in the determination of clinical sample containing mixed gefitinib and ritonavir was finally proved, facilitating impressive specificity and accuracy. Considering the simplicity and reliability, our strategy has great potentials to be applied in clinical blood drug identification and concentration monitoring.
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高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Lun Han,Xu Wang,Bin Yu,Xiaoyuan Qin,Baocheng Liu,Xu Han,Huifen Yuan,Bin Yu,Zhiqi Zhao
Glucose is a key biomarker of diabetes, and effective glucose monitoring methods are crucial to the prevention and management of diabetes. Therefore, in this paper, Fe 3 O 4 /DEX/PDA@Au (Raman reporters) @Au nanocomposites were synthetized that with DTNB (5,5′-dithiobis(2-nitrobenzoic)), MMTA (2-mercapto-4-methyl-5-thiazole acetic acid), MBA (4-mercaptobenzoic acid) and 4-Mpy(4-Mercaptopyridine) were used separately as Raman reporters. Fe 3 O 4 and PDA (Polymerized dopamine) could supply more high surface area of active sites and high SERS (Surface-Enhanced Raman Scattering) substrate, which has high stability and reproducibility. Dextran coating is an effective way to prepare biocompatible materials TEM, XRD, TG and VSM were used to analyze the size, morphology and magnetic properties of the nanocomposites. Fe 3 O 4 /DEX/PDA@Au(Raman reporters)@Au that integrates a multi-hotspot structure and magnetic separation techniques were studied the enhancement effect of Raman spectra, and glucose solutions with different concentrations were tested. Furthermore, the optimal Fe 3 O 4 /DEX/PDA@Au(Raman reporters)@Au nanocomposites were supplied as SERS substrates for detection of glucose accurately and quickly in sweat. SERS signal intensity is linearly correlated with glucose concentration within the measurement range of 5 × 10 -3 to 10 mM, and the minimum detectable concentration is 5 µM. The Fe 3 O 4 /DEX/PDA@Au(Raman reporters)@Au nanocomposites exhibit high reliability, specificity and repeatability of the strategy were then verified by practical detection of sweat.
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PubMed
高影响因子
MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 3
·1-12
·
IF 5.3
Wang Hongjun,Bian Ziyang,Wang Yue,Yang Zhenshan,Niu Huijuan,Li Hefu
A dual-functional biomimetic surface-enhanced Raman scattering (SERS) substrate composed of grating/microcavity arrays (GCA) was developed for on-site monitoring of pesticides on fruit peels and in surface water. The hierarchical GCA structure was fabricated by molding a negative polydimethylsiloxane (PDMS) replica from lily petals, followed by the generation of grating wrinkles through oxygen plasma treatment. After the deposition of silver nanoparticles (Ag NPs) through magnetron sputtering, the optimal Ag NPs@GCA substrate exhibits high sensitivity, good uniformity, and reproducibility. Moreover, due to its optical transparency, mechanical stability, and hydrophobic properties, the Ag NPs@GCA substrate combined with a handhold Raman spectrometer can be used for on-site determination of pesticides in real samples. The limit of detection (LOD) for thiram on the surfaces of apples, pears, and cherry tomatoes were 2.86 × 10 −7 , 5.03 × 10 −7 , and 7.25 × 10 −7 M, respectively. For malachite green, the LODs were 9.04 × 10 −8 M in lake water and 4.83 × 10 −7 M on fish scales. The results indicate the developed dual-functional Ag NPs@GCA substrate has great potential for applications in food safety assessment and environmental pollutant monitoring. Graphical abstract
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PubMed
高影响因子
TALANTA
·
2025
·
IF 6.1
Ao Chen,Yiwen Gui,Kuang Luo,Ning Cai,Jumei Li
In this study, a novel magnetic composite, Ag@Fe 3 O 4 /UiO-66-NH 2 (Ag@FUN), was developed by incorporating a porous metal-organic framework (MOF), UiO-66-NH 2 , which offers selective enrichment capabilities and facilitates solar-driven photoreduction of Cr(VI). The surface coverage of silver nanoparticles on Ag@FUN was precisely controlled by adjusting the AgNO 3 feed concentration, enabling tunable SERS sensitivity. SERS measurements revealed that the Ag@FUN composites exhibited strong signal intensity for Cr(VI), along with excellent signal reproducibility and storage stability. These composites were capable of detecting Cr(VI) at concentrations of as low as 7.81 × 10 -8 M in tap water and 8.89 × 10 -8 M in pond water. The remarkable SERS performance is attributed to the porous MOF structure, which enriches Cr(VI) via Zr–O coordination, electrostatic interactions, and pore-filling effects. Importantly, under simulated sunlight, Ag@FUN effectively reduced Cr(VI) within 70 minutes. The composites also demonstrated outstanding recyclability, retaining their SERS sensitivity and photocatalytic efficiency through five consecutive "detection–reduction" cycles. Overall, the Ag@FUN composites developed in this work exhibit high SERS sensitivity and robust photocatalytic activity, offering significant potential for environmental monitoring and ecological remediation.
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高影响因子
MICROCHIMICA ACTA
·
2022
·Vol. 189
·期 5
·1-9
·
IF 6.408
Zhang Xinxi,Chen Lulu,Fang Xuejiao,Shang Yunsheng,Gu Haixin,Jia Wenlin,Yang Guohai,Gu Yingqiu,Qu Lulu
Chlorpyrifos is one of the most widely used organophosphate insecticides in agricultural production. Nevertheless, the residues of chlorpyrifos in agricultural by-product seriously threaten human health. Thus, the ultrasensitive detection of chlorpyrifos residues in agri-food products is of great demand. Herein, an AuNP/HNT-assembled disposable paper SERS substrate was prepared by an electrostatic self-assembly method to detect chlorpyrifos residues. The AuNP/HNT paper substrate exhibited high SERS activity, good reproducibility, and long-term stability, which was successfully used for quantitative detection of chlorpyrifos; the detection limit reached 7.9 × 10 −9 M. For spiked apple samples the calculated recovery was 87.9% with a RSD value of 6.1%. The excellent detection ability of AuNP/HNT paper-based SERS substrate indicated that it will play an important role in pesticide detection in the future. Graphical abstract AuNP/HNT assembled disposable paper SERS substrate was prepared by an electrostatic self-assembly method to detect chlorpyrifos residues in fruits.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
Rui Wang,Yimin Tang,Yanan Lu,Zhiyu Wang,Xin Jiang,Bing Zhao,Libin Yang
Constructing a heterogeneous structure with the combined contribution of electromagnetic (EM) and chemical (CM) mechanisms, while enabling all components to contribute to each mechanism, is an effective strategy for developing new high-performance surface-enhanced Raman scattering (SERS) substrate. In this work, a novel 3D/1D MoS 2 flower-like microspheres@Au nanowires (MoS 2 FMs@Au NWs) heterojunction SERS matrix platform is successfully developed through morphology regulating and interface engineering strategies. The enhancement factor of SERS matrix is as high as 3.97 × 10 9 . The theoretical simulations and experiments reveal the combined contribution of EM and CM mechanisms. The dual EM effects (Mie resonance triggered by 3D MoS 2 FMs and hotspot effect of high-density Au NWs customized by highly ordered MoS 2 ) and the multidimensional CM contributions (high-efficiency carrier separation of MoS 2 triggered by heterostructure and high carrier utilization rate from hot electron excitation of Au NWs) can be synchronously achieved for boosting SERS activity of the heterojunction. More meaningfully, the developed SERS matrix can realize an ultra-sensitive detection for trace fungicide residues (crystal violet and malachite green) in real water system. This discovery provides new insights and perspectives for developing novel function-customized SERS substrates, aiming to advance the practical application of SERS technology.
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高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Hui Pan,Meng Jin,Fang Zhang,Xuelei Chen,Mengping Zhang,Haiyan Wei,Xiao Meng,Wenwen Chen,Zhihu Zhang,Cuijuan Wang
Health concerns over mixed pesticide residues highlight the need for rapid detection methods. This study developed a multifunctional point-of-use (POU) sensor that integrates separation, enrichment, and surface-enhanced Raman spectroscopy (SERS) using high-index Au trisoctahedrons (TOHs) and metal-organic frameworks (MOFs) on polyamide 6 (PA-6) film. The Au TOHs with sharp tips and high index facets offer excellent SERS performance, while MOFs facilitate analyte enrichment and separation. The flexible PA-6 film was used as an absorbent for the initial adsorption. Using the AuTOHs@ZIF-67/PA-6, we achieved on-site detection of chlorfenapyr (CFP) and emamectin benzoate (EB) in 5 min without pre-treatment, significantly faster than traditional methods. Detection limits were 0.68 ppb for CFP and 0.26 ppb for EB on cucumber surfaces, and 0.13 ppb and 0.95 ppb, respectively, in cucumber juice, well below tolerance levels. This method shows great promise for detecting pesticide mixtures in non-laboratory settings, offering a new POU alternative.
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高影响因子
APPLIED SURFACE SCIENCE
·
2021
·
IF 6.707
Yue Tian,Qingqiang Cui,Hui Ma,Anxin Jiao,Chang Wang,Mengya Zhang,Linqi Zheng,Xuelin Wang,Shuang Li,Guihua Li,Ming Chen
Based on plasmonic metallic nanomaterials (NMs) with unique local surface plasmon resonance (LSPR), the photo-excited hot carrier-driven hydrogenation reaction becomes a new family of photocatalytic transformations in recent years. However, the high work function and rapid hot-carrier recombination of plasmonic NMs create huge barriers for widespread practical application. Herein, we propose a fascinating reactor of up-regulated electrochemical LSPR (EC-LSPR) driven hydrogenation reaction via the construction of hierarchical Au pine needles (H-Au PNs) with enhanced lightning rod effect under appropriate extra electric field. The plentiful elongated Au branches with sharp corners and edges can be served as excellent electron-transport channels for facilitating photo-excited hot carrier transmission and accelerating hot electron collection at nano-tips after plasmon decay. Additionally, the extra electric field with the applied voltage of − 0.8 V further improves the surface charge density and the internal polarization of H-Au PNs, boosting the separation efficiency of hot carriers as well as reducing the photoelectrochemical (PEC) potential on H-Au PNs. It directly leads to an effective activation enthalpy reduction to reach above the energy threshold of water splitting, which can achieve the direct plasmon-driven PEC-hydrogenation conversion of 4-nitrothiophenol (4-NTP) to 4-aminothiophenol (4-ATP) in aqueous solution, and the conversion rate constant is about 5 times higher than bare EC-driven conversion. The present work provides a new opportunity for the emerging direct plasmon-driven hydrogenation reaction.
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高影响因子
FOOD CHEMISTRY
·
2022
·
IF 9.231
Jingying Yang,Mingfei Pan,Xiao Yang,Kaixin Liu,Yang Song,Shuo Wang
In-situ, real-time and sensitive detection of multiple pesticide residues in food is always an important issue in food safety. Herein, a novel multifunctional bead-string like Ag nanowires@zeolitic imidazolate framework-8 (Ag NW@ZIF-8) core–shell nanochains was successfully synthesized and utilized as surface-enhanced Raman scattering (SERS) substrate for in-situ and simultaneous detection of pesticide residues . Due to the microporous framework structure of ZIF-8 shell and the plasmon property of Ag NWs core, the Ag NWs@ZIF-8 composite was demonstrated to have strong adsorption performance and high SERS activity (enhancement factor: 4.6 × 10 7 ). The Ag NWs@ZIF-8 based SERS strategy achieved sensitive detection of two water-insoluble pesticides methylparathion and carbaryl with detection limits as low as 7.6 × 10 −9 M and 5.7 × 10 −9 M, as well as the in-situ detection of multi-pesticide residues on fruits and vegetables with acceptable recovery ranged from 77.4 % to 117.5 %, demonstrating its great potential for in-situ and rapid detection of food contaminants.
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高影响因子
ANALYST
·
2021
·Vol. 146
·期 15
·4858-4864
·
IF 4.616
Shuling Xu,Hefu Li,Meng Guo,Lei Wang,Xia Li,Qingwang Xue
DBP, one of the phthalic acid esters (PAEs), is known as an endocrine disruptor and is toxic to humans in abnormal concentrations. Here, a high-density and ordered SERS substrate based on the self-assembly of triangular Ag nanoplate (TAgNP) arrays is developed for DBP detection. Benefiting from the ordered arrangement and sharp corners of TAgNPS, the arrays can provide sufficient and uniform hotspots for reproducible and highly active SERS effects. Using Rhodamine 6G (R6G) as a reporter molecule, the SERS enhancement factor (EF) of the TAgNP arrays was found to be as high as 1.2 × 107 and the relative standard deviation was 6.56%. As a trial for practical applications, the TAgNP array substrates were used for the detection of dibutyl phthalate (DBP) in edible oils. In this assay, edible oil samples were added to hexane as an organic phase for the formation of the TAgNP arrays, which caused DBP to be loaded at hotspots. DBP in edible oils could be identified at concentrations as low as 10−7 M. This SERS substrate based on the TAgNP arrays has great potential applications in the high sensitivity and reproducible detection of contaminants in food.
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高影响因子
危险品化学品经营许可证（带存储）