MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 4
·258
·
IF 5.4
Liu Yeru,Zhang Mengxue,Zhou Yifan,Zhao Xiaolei,Li Xiangli,Liu Hongwei,Cai Qiyong,Liu Song
A reversed positive-signal electrochemical immunosensor was developed for ultra-sensitive tetracyclines (TC) detection, leveraging a synergistically engineered interface of conductive urchin-like Au@Pt nanoparticles (NPs) and insulating SiO 2 nanoprobes. The Au@Pt NPs provide a high-performance electroactive foundation that significantly expands the effective surface area and accelerates interfacial electron transfer kinetics. A ‘signal-on’ mechanism was innovatively constructed by utilizing the mass-transport resistance and steric hindrance of bulky, insulating SiO 2 -antibody conjugates. In the absence of TC, the anchoring of SiO 2 nanoprobes creates a dense insulating barrier that truncates electron tunneling paths. Conversely, the competitive recognition of free TC prevents probe anchoring, removing the barrier and restoring charge transfer, which results in a significantly enhanced signal. This strategy effectively transforms passive dielectric blocking into a sensitive electrochemical response, allowing effective signal amplification of subtle recognition events. Under optimized conditions, the sensor exhibited a linear differential pulse voltammetry (DPV) response from 20 fg/mL to 20 ng/mL, with detection limits of 4.55 fg/mL and 11.58 fg/mL for the glassy carbon electrode and the screen-printed electrode, respectively. The sensor demonstrated excellent specificity against structural analogs, high reproducibility, and reliable recovery in spiked milk samples. This work validates the efficacy of using cost-effective insulating nanomaterials for high-sensitivity biosensing, offering a robust tool for food safety surveillance.
Section
Graphical
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高影响因子
CHROMATOGRAPHIA
·
2026
·
IF 1.6
Zhao Xingyun,Liu Xiaojian,Zhang Zhenwei,Jin Jiangyan,Yang Siyu,Zhao Chengxiao,Wu Rongfang,Zhang Liyun
Mesoporous silica particles were synthesized via investigating polymerization-induced colloidal aggregation (PICA) reaction process in our laboratory. Mesoporous microspheres with a particle size of about 2~7 μm and various surface morphology were first compared via varying the pH and molar ratio of formaldehyde/urea in the PICA process. The effects of salts and surfactant on the preparation were further investigated by fixing pH and molar ratio formaldehyde/urea (1:1.5), demonstrated that the particle size distribution became narrower when potassium sulphate and a nonionic surfactant were added together. The morphology, pore size distribution and the specific surface area of the synthesized mesoporous SiO 2 microspheres were observed and characterized by optical microscope, scanning electron microscope (SEM), dynamic light scattering (DLS), and specific surface area (BET) analysis. In the present study, synthesized materials modified octadecyltrichlorosilane (PICA-3@C18) were slurry-packed into a chromatographic empty column, resulting in successful separation of nonpolar compounds. Furthermore, the synthesized materials were functionalized with aminopropyl trimethoxysilane under optimized conditions and exhibited outstanding separation abilities. Aminopropyl trimethoxysilane was further bonded onto commercial SiO 2 , resulting in a stationary phase that exhibited better chromatographic performance than commercial amide columns, NH 2 columns, and other HILIC columns. This work provides insight into retention behavior in HILIC mode and offers a foundation for the development of other amine-based HILIC stationary phases.
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Processes
·
2026
·Vol. 14
·期 12
·1998
·
IF 3.4
Zhuangzhuang Zhang,Lingling Ma,Yang Shao,Diandou Xu,Min Luo
To tackle the environmental challenges associated with industrial oily wastewater discharges and recurrent marine oil spill incidents, developing high-efficiency oil–water separation technologies represents a pressing environmental challenge. This research presents a novel design approach comprising the deposition of a stable SiO2anchoring layer followed by the fabrication of a PDA/CS crosslinked coating, thereby achieving successful construction of a superhydrophilic/underwater superoleophobic (SH/UWSO) coating on stainless steel meshes (SSM). In the first step, SiO2microspheres were deposited via vapor deposition to create a micro-rough surface architecture. Subsequently, a dopamine/chitosan (DA/CS) reaction solution was introduced to form a Polydopamine/chitosan (PDA/CS) coating, yielding a SiO2@PDA/CS-SSM separation membrane. The resulting membrane exhibited separation efficiencies surpassing 99% for various oil–water mixtures, achieving a flux of 1.24 × 105L·m−2·h−1in petroleum ether systems. Notably, the membrane maintained high efficiency and structural stability even after 25 separation cycles, immersion in strong acid and base solutions for 72 h, and 100 abrasion tests. The rational design of the anchoring and crosslinking layers endows SiO2@PDA/CS-SSM with high efficiency and stability, making it an effective oil–water separation material.
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ACS Sustainable Chemistry & Engineering
·
2026
·
IF 7.6
Quanlan Liao,Wanzhen Du,Jialong Ou,Jianxin Cao,Lunbao Chen,Tianxiang Zhao
Mechanochemistry offers an environmentally benign and highly efficient route to heterogeneous catalysts. In this work, mesoporous SiO2 serves as both a ball-milling aid that enhances grinding efficiency and a porous support for the in situ generation and immobilization of organourea-containing ionic polymers. During the mechanochemical process, the polymers are assembled within the mesopores and onto the external surface of SiO2, thereby improving the accessibility of ionic active sites for catalysis. This solvent-free strategy eliminates the need for toxic organic solvents and significantly reduces synthesis time compared with conventional solvothermal or reflux routes that typically require several hours to days, while exploiting the synergistic interactions between the SiO2 support and the ionic polymer matrix. The optimized catalyst, denoted TEB-O@Si-8(50%), achieves 99% conversion of various epoxides to the corresponding cyclic carbonates under mild conditions (100 °C, 1 MPa CO2, 12 h) and retains high catalytic activity over five consecutive cycles. Kinetic studies and in situ FTIR spectroscopy reveal that urea and hydroxyl groups polarize the C–O bond of the epoxide through hydrogen bonding, while bromide ions facilitate nucleophilic ring-opening. This work overcomes the prolonged synthesis times and reliance on volatile solvents associated with conventional catalyst preparation and provides a sustainable, scalable route to high-performance heterogeneous catalysts for CO2 conversion.
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MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Yin Li,Qian An,Xingcan Li,Chunya Li,gang Luo
Nonalcoholic fatty liver disease (NAFLD), a highly prevalent clinicopathological disorder characterized by excessive hepatic lipid accumulation, insulin resistance, and chronic inflammation, represents a growing global health challenge. Since inflammation plays a pivotal role in NAFLD progression, the sensitive and selective detection of inflammatory biomarkers is essential for early diagnosis. Herein, a ratiometric fluorescent probe (BDY-HOCl) based on boron dipyrromethene (BODIPY) was developed for in situ monitoring of hypochlorous acid (HOCl), a key factor for inflammatory responses. BDY-HOCl operates through HOCl-induced oxidative cleavage of an alkene linker between BODIPY and a Fischer aldehyde moiety, producing two distinct emission peaks with minimal spectral overlap and environmental interference, thereby ensuring accurate ratiometric fluorescence quantification. To further enhance stability and selectivity, BDY-HOCl was covalently anchored onto amine-functionalized SiO 2 @covalent organic frameworks (SiO 2 @COFs) via Schiff base condensation, yielding SiO 2 @COFs-BDY-HOCl . This nanocomposite can effectively reduce solvent-induced fluorescence quenching and improved HOCl detection with a low limit of detection (LOD) of 3.8 nM. Importantly, SiO 2 @COFs-BDY-HOCl enabled real-time fluorescence imaging of HOCl fluctuations in palmitate-stimulated hepatocytes, thereby providing a powerful platform for the early diagnosis of NAFLD through ratiometric fluorescence imaging HOCl, an inflammation-related factor.
研究领域:
生物医学工程
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分析化学
·
分子成像
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纳米材料
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肝脏病学
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炎症研究
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JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2025
·
IF 4.6
Qiao Yan,Pingping Zhang,Menglin Wang,Ling Ma,Ke Wang,Kaoqi Lian
This study aimed to synthesize a novel magnetic covalent organic framework (COF)-based material and establish an efficient magnetic solid-phase extraction (MSPE) method for the determination of benzimidazoles (BZDs) in honey. Given the abundant nitrogen atoms in BZDs, the target material (Fe₃O₄@SiO₂@MPA-TAPT-COF) was designed with Fe₃O₄ as the magnetic core and a COF shell polymerized from 5-bromobenzene-1,3-dicarbaldehyde (MPA) and 4,4',4''-(1,3,5-triazine-2,4,6-triyl) trianiline (TAPT). The synthesized Fe₃O₄@SiO₂@MPA-TAPT-COF exhibited considerable specific surface area, good magnetic responsiveness, and excellent reusability. An MSPE method using Fe₃O₄@SiO₂@MPA-TAPT-COF as the adsorbent was developed for the purification of BZDs in honey, followed by quantification via ultra-performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS). This method featured simple operation, high sensitivity, and good efficiency. Under optimized MSPE conditions, It showed good linearity for 17 BZDs in the concentration range of 0.2–100 μg/L, with correlation coefficients (R²) ≥ 0.9991. The limits of detection (LODs) for BZDs in honey were as low as 0.009–0.342 μg/kg. For spiked honey samples, the recoveries of the 17 target BZDs ranged from 61.44 % to 118.90 %.These results confirm that Fe₃O₄@SiO₂@MPA-TAPT-COF is a promising adsorbent for sample pretreatment, and the developed method provides a reliable tool for the sensitive and efficient analysis of BZDs in honey.
研究领域:
分析化学
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食品安全
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环境科学
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材料科学
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ENZYME AND MICROBIAL TECHNOLOGY
·
2020
·
IF 3.448
Jia-Qin Wu,Xiao-Mei Xu,Ding-Lin Wang,Neng-Bing Long,Rui-Feng Zhang
Novel nano-composites were prepared by coating epoxy resin-based cationic polymer in nano-thickness via in-situ curing on the nano-wall of macroporous SiO 2 with pore size of 0.5∼1 μm. By changing the thickness of polymer coating the specific surface area and porosity varied in range of 115∼74 m 2 /g and 90.4∼83.9 %, respectively. Through ion exchange phospholipase D (PLD, from Streptomyces sp ) was efficiently immobilized on the nano-composites as support and the immobilized PLD was applied for the highly efficient synthesis of phosphatidylserine (PS). The loading amount of PLD on the nano-composited support reached to a maximum of 90.2 mg/g support , 4 times as high as that on the pure macroporous silica. The specific activity of the immobilized PLD reached as high as 16,230 U/g protein , while that of free PLD was 18,780 U/g protein . Under a wide range of temperature and pH the stability and activity of the immobilized PLD were greatly improved as compared with the free ones. Under optimized conditions at 45 °C and pH 7.0, the PS yield reached as high as 96.2 % within 40 min. After 28 days storage the immobilized PLD retained 82.2 % of original activity, and after 12 cycling reuses it retained 79.3 % of PS yield, which indicated that the immobilized PLD exhibited good stability.
研究领域:
生物化学
·
酶工程
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iScience
·
2022
·
IF 6.107
Tongyang Song,Yuanyuan Qi,Chen Zhao,Peng Wu,Xiaohong Li
Summary An ultrastable and efficient Cu@C/SiO 2 nanocatalyst was fabricated for the hydrogenation of ethylene carbonate, in which Cu nanoparticles are encapsulated by sorbitol-derived graphitized carbon overlayers. During the calcination of Cu-sorbitol/SiO 2 precursors under N 2 atmosphere, sorbitol decomposed to CO and CO 2 . The in situ generated CO not only reduced Cu 2+ to Cu 0 /Cu + , but also formed graphitized carbon overlayers on the Cu surface via the disproportionation of CO. The Cu@C/SiO 2 catalyst exhibited superior catalytic performance (91% MeOH yield and 43.6 h −1 TOF) at a H 2 /EC molar ratio of 20. Of particular note, the Cu@C/SiO 2 catalyst showed remarkable long-term stability during 736 h time-on-stream test without any deactivation. The graphitized carbon overlayers on the surface of Cu nanoparticles not only functioned synergistically with the surface Cu 0 /Cu + sites to promote the EC hydrogenation but also suppressed the sintering of Cu nanoparticles. Furthermore, the interaction of Cu nanoparticles and graphitized carbon overlayers stabilized the surface Cu + /(Cu 0 +Cu + ) ratio.
研究领域:
材料科学
·
化学工程
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Materials Today Communications
·
2025
·
IF 4.5
Kecheng Lu,Pengjie Fan,Zebing Xu,Guang Deng,Wenbin Jiang,Zhaojin Ran,Ran Mo,Chenggang Hao,Hua Cen,Zhongmin Wang
To address the issues of severe corrosion (especially in chloride-rich marine environments) and microbial adhesion-induced biofouling that limit the service life of aluminum alloys, this study developed an integrated surface protection system for aluminum substrates by synergizing anodic oxidation and composite functional coating technologies. First, an anodized aluminum oxide (AAO) layer was constructed on 5052 aluminum alloy, then VS 2 micro-nano particles were synthesized via hydrothermal method while SiO 2 nanoparticles were hydrophobically modified with 1H,1H,2H,2H-perfluorodecyltriethoxysilane (PFDTES, denoted as P-SiO 2 ), and finally P-SiO 2 and VS 2 (optimal mass ratio of 3:1) were sprayed onto the AAO surface with epoxy resin as binder to form the organic-inorganic superhydrophobic composite coating (AAO@P-SiO 2 /VS 2 ). Multiple characterization techniques including XRD, XPS, FTIR, SEM, HRTEM, ICP-OES, laser particle size analyzer and surface roughness tester were used to systematically confirm the phase purity, elemental composition, valence state, micro-nano morphology, thickness, stoichiometry and roughness of the coating and its components. Performance tests showed that the composite coating exhibited excellent superhydrophobicity (water contact angle of 152.12°, sliding angle of 4.6°) and corresponding self-cleaning ability, significantly enhanced corrosion resistance (self-corrosion current density of 6.053 ×10⁻ 11 A/cm 2 , 1 order of magnitude lower than AAO and 5 orders of magnitude lower than bare aluminum alloy; low-frequency impedance modulus of 4.50 ×10 8 Ω·cm 2 ), outstanding antibacterial activity (99.89 % antibacterial rate against Pseudomonas aeruginosa , and effective inhibition against Escherichia coli and Staphylococcus aureus ) as well as good stability and durability (excellent wear resistance, high adhesion of 18.20 MPa, and water contact angle remaining above 150° after 30 days of immersion in 3.5 wt% NaCl solution). This study innovatively integrates anodization with PFDTES-modified SiO 2 and VS 2 -based antibacterial composite coating, providing a cost-effective and sustainable solution for enhancing the multifunctional protection of aluminum alloys, which is of great significance for extending the service life of metal equipment, especially in marine and harsh industrial environments.
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ACS Omega
·
2025
·
IF 4.3
Yoshiaki Nomura,Manabu Kiguchi,Zhongoing Liang,Mei Ma,Akira Fujishima,Nobuhiro Hanada
The triazine herbicides simetryn and prometryn may cause damage to nontarget crops due to persistent contamination of agricultural water. Photocatalysis is a promising technology for the degradation of agricultural pollutants. This study provides the first systematic integration of photocatalytic herbicide degradation with live plant bioassay validation using cost-effective Fe3O4/SiO2/TiO2 magnetic photocatalysts synthesized by a simple coprecipitation method suitable for large-scale production. The phytotoxicity of herbicide-containing water was evaluated using pak choi, a crop sensitive to triazines. Both herbicides were completely decomposed in water within 240 min after UV irradiation, and their phytotoxicity also disappeared. In the plant toxicity evaluation, prometryn exhibited temporary high toxicity exceeding that of the untreated 10 ppm solution during the photodegradation process. In previous photocatalyst studies, evaluations relied on either chemical analysis or biological tests. In this study, we developed a new rapid toxicity screening technique using plant seedlings and established a safety evaluation protocol integrating chemical analysis and plant toxicity tests. This method represents the first approach to comprehensively evaluate the safety of agricultural water.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2025
·
IF 8.3
Guang Yang,Qiang Hu,Haiping Yang,Yang Yang,Wei Cheng,Jiageng Xia,Hanping Chen
Catalytic reforming technology holds significant potential for treating biomass gasification tar. However, the design of catalysts that offer high activity, low carbon deposition, and long-term stability remains a challenge. In this study, Ni@SiO 2 yolk-shell catalysts were synthesized and evaluated for their activity and stability in toluene steam reforming. The Ni@SiO 2 -10 catalyst demonstrated excellent stability and activity, maintaining a 100 % toluene conversion rate over a 120-h test period with virtually no carbon deposition after reforming. In contrast, Ni/SiO 2 and Ni/Al 2 O 3 catalysts, synthesized by incipient wetness impregnation, showed significant sintering and carbon deposition after use. Under identical support conditions, Ni@SiO 2 reduced the initial reaction temperature for toluene steam reforming from 462 °C to 418 °C. Increasing the Ni loading significantly enhanced the number of active sites, decreased the size of the SiO 2 microspheres, and thinned the SiO 2 shell layer, thereby elevating the toluene conversion from 72 % to 100 %. Both temperature and the GHSV (gas hourly space velocity) had a significant impact on catalytic performance, with conversion rates stabilizing at 700 °C and an GHSV = 24500 h −1 . The yolk-shell structure of Ni@SiO 2 promoted high Ni dispersion, reducing aggregation and carbon deposition, which were key to its high activity and stability. These findings are crucial for the development of catalysts for biomass tar reforming.
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RSC Advances
·
2017
·Vol. 7
·期 21
·12856-12870
·
IF 3.108
Yan Jiang,Zheng Jin,Chen Chen,Wubiao Duan,Bo Liu,Xidong Chen,Feihua Yang,Jianping Guo
SiO2/P25 (SP) composites doped with different contents of cerium were prepared by a hydrothermal process at a relatively low temperature in this experiment. The resulting Ce–SiO2/P25 (CSP) composites were successfully characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), high resolution transmission electron microscopy (HRTEM), N2-physisorption, UV-vis diffuse reflectance spectroscopy (DRS), and photoluminescence spectroscopy (PL). The photocatalytic activities of the as-obtained catalysts were evaluated for the degradation of organic dyes, including Methylene Blue (MB) and Reactive Red 4 (RR4), under visible-light irradiation. The best results were obtained for a cerium loading of 5 mM. The CSP-5 nanoparticle showed the 91.8% decomposition of MB and 90.2% decomposition of RR4 in the liquid phase at room temperature under visible-light irradiation in a photoreactor, and the corresponding hydrogen evolution rate was 2.315 mmol g−1, which was more efficient than that of pristine P25. Remarkably enhanced activities towards the photodecomposition of several organic compounds were observed depending on the synergistic effect between silicon and cerium. The Ce–SiO2/P25 structure leads to efficient light harvesting into the visible-light region by forming new energy levels inside the nanoparticles and then electron–hole recombination could be effectively inhibited. The BET surface area measurement was used to provide an insight into the enhanced photocatalytic activity of the CSP composites, which was also understood to be because of the relative enhancement of the adsorption of organic molecules on the photocatalyst surface. In addition, the effect of the initial pH values on the photocatalytic degradation of different dyes using CSP-5 was investigated. Finally, a good recyclability of CSP-5 was demonstrated compared to that of pristine P25. Herein, the photocatalytic mechanism has been concretely explained.
研究领域:
材料科学
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环境化学
·
光催化
·
纳米材料
·
能源材料
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危险品化学品经营许可证（带存储）