JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
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2020
·
IF 2.69
Qianqian Qi,Xianwu Zeng,Licong Peng,Hailiang Zhang,Miao Zhou,Jingping Fu,Jianchao Yuan
Herein, we construct a charge - switchable polymer nano micelles poly (2-(hexamethyl eneimino) ethyl methacrylate) - b - poly (ethylene glycol) monomethyl ether methacrylate) - b - poly (diethyl enetriaminepentaacetic acid methacrylate) - b - poly (1-vinyl imidazole) - b - poly (4-vinyl phenylboronic acid) (PC7A-PEG-DTPA-VI-PBA) in different pH solutions. DOX released faster from micelles in a weakly acidic environment (pH 5.0) than at pH 7.4. In order to enhance the anti-tumor effect, the imidazole functional groups in the polymer were used to coordinate CdSeTe quantum dots (QDs) for photodynamic treatment (PDT). In addition, the surfaces of the micelles were further decorated with phenylboronic acidas a targeting group, using DTPA chelating 99mTc for SPECT imaging.It has been successfully demonstrated that the nanoparticles have a good cumulative effect on the tumor site.The structure of the polymer was characterized by 1HNMR. The morphology and particle size of the micelles were characterized by transmission electron microscopy (TEM) and dynamic light scattering (DLS). The drug loading capacity (DLC) and drug loading efficiency (DLE) of the micelles were analyzed by ultraviolet visible spectroscopy. And the pH-sensitive drug release and cytotoxicity of the micelles were verified in vitro. In vitro experiments showed that the nano micelles were noncytotoxic to different cell lines, while DOX@CdSeTe@PC7A-PEG-DTPA-VI-PBA inhibited the proliferation and promoted the apoptosis of B16F10 cells. An in vivo study with C57BL tumor-bearing mice indicated that DOX@CdSeTe@PC7A-PEG-DTPA-VI-PBA nano micelles efficiently inhibited tumor growth. Results showed that the nano micelles had good pH responsibility and biocompatibility, and the loaded DOX could be released in the weak acidic environment of tumor cells, and it was expected to be a good drug delivery system.
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高影响因子
NEW JOURNAL OF CHEMISTRY
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2020
·Vol. 44
·期 41
·17984-17992
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IF 3.288
Guoning Chen,Qianqian Hu,Hua Shu,Lu Wang,Xia Cui,Jili Han,Kamran Bashir,Zhimin Luo,Chun Chang,Qiang Fu
The sensing method for hydrogen peroxide could also be employed to detect H2O2-bioprecursors in the presence of oxidase. However, the sensitivity of the conventional method is limited, and the catalytic stability and recyclability of enzymes also need to be improved. In this study, glucose was chosen as a typical representative H2O2-bioprecursor to design a fluorescence sensing system for H2O2-bioprecursors based on a magnetic immobilized enzyme and CdTe quantum dots. The magnetic immobilized enzyme was fabricated by a cross-linking method to enhance the stability and recyclability of the enzyme. The obtained product was characterized by scanning electron microscopy, transmission electron microscopy, energy dispersive spectrometry, and vibrating sample magnetometry, respectively. The CdTe quantum dots were prepared by a hydrothermal method, and revealed a maximum emission peak at about 610 nm under the maximum excitation light (339 nm). The developed CdTe QDs exhibited excellent sensing performance for hydrogen peroxide. The prepared immobilized enzyme and quantum dots were used to develop a fluorescence sensing system and were successfully exploited to detect a typical H2O2-bioprecursor (glucose) in the presence of glucose oxidase. The method exhibited good linear performance in the concentration range of 1–20 μg mL−1, and good recoveries ranging from 106.2–117.7%. This study demonstrated that the strategy could be extended to detect more H2O2-bioprecursors.
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CARBON
·
2020
·
IF 8.821
Weilin Lin,Yue-e Huang,Lunhui Guan,Xiaoying Huang,Li Li,Ke-Zhao Du,Xiaohui Wu
A strategy of doping chalcogen-heteroatom in red phosphorus (RP) nanoparticles is adopted to improve the electrochemical performance of RP based composites as lithium storage materials. RP nanoparticles embedded in porous carbon with chalcogen-doping (S-, Se- and Te–P@PC) composites are synthesized via a facile evaporation-condensation approach. The large volume expansion of RP upon cycling is well mitigated by nanoscale feature and buffered by pore-closed carbon matrix. The extra fillings of chalcogen dopants lessen the specific surface areas of the doped composites, minimizing parasitic surface reactions of anode materials with electrolyte that can lead to high initial coulombic efficiencies. The high conductivity of Se dopant and the formed conductive Li–Se/Li–Se–P confer the Se–P@PC anode with improved electron/ion transport properties to deliver a superior fast-charging capability over 900 cycles. Moreover, a high-rate capacity of 908.5 mA h g −1 at 5.0 A g −1 and an impressive reversible capacity of 848.2 mA h g −1 even after 1800 cycles at 1.0 A g −1 of Se–P@PC surpass most of reported RP-based anode materials.
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Nano Energy
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2020
·
IF 16.602
Zhenjing Jiang,Tongyao Zhao,Jinjun Ren,Yanfei Zhang,Yuanzheng Yue
Recently it has been demonstrated that the electrochemical performances of semiconducting amorphous anodes for Li-ion batteries (LIBs) can be greatly enhanced by the discharging/charging induced nanocrystals . However, the structural origin of those nano-domains remains elusive, although it is critically important for designing superior glass anodes for LIBs. In this work, we probe the local structural evolution in a glass anode for LIBs during cycles by means of the state-of-the-art solid-state nuclear magnetic resonance (SSNMR). The structural evolution is manifested as the disassociation of the structural network into isolated units, followed by formation of different types of nano-domains with a high degree of order. These domains are highly favorable for rate capability and long-term cycling stability. From SSNMR and electrochemical characterizations, we have obtained a clear picture about the detailed redox reactions . These findings provide a chemical principle that is helpful for designing the stable glass electrodes for high-performance LiBs.
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APPLIED SURFACE SCIENCE
·
2020
·
IF 6.182
Li Wang,Daqing Yu,Baoquan Huang,Ziyuan Ou,Li Tao,Lili Tao,Zhaoqiang Zheng,Jun Liu,Yibin Yang,Aixiang Wei,Yu Zhao
Two-dimensional (2D) transition metal dichalcogenides materials have recently been explored as possible substrates for surface-enhanced Raman spectroscopy (SERS). However, in comparison to the conventional noble-metal-based counterpart, most of the 2D materials have very small area for SERS measurement, which is a big limitation toward practical applications. Herein, we presented our study of SERS using substrate-scale continuous ReS 2 monolayer films on flexible mica substrate. We demonstrated that the charge transfer between the target molecules and the atomically thin ReS 2 can be modulated by the underlying substrate of ReS 2 , resulting in greatly different suppressing level of FL background. Kelvin probe force microscopy revealed a large difference of surface potential between ReS 2 /SiO 2 and ReS 2 /mica, suggesting that the strong FL quenching of molecular on ReS 2 /mica might be attributed to the inert surface of layered mica. The large-area ReS 2 monolayer films on mica show a detection limit of R6G molecule around 10 −7 M and a robust SERS performance after an exposure in air for one month and repeated bending for 1000 times. Our work explores the practical application of 2D ReS 2 for molecular detection via SERS technique.
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ACS Applied Materials & Interfaces
·
2020
·
IF 8.758
Heping Cui,Kai Zheng,Zhongjian Xie,Jiabing Yu,Xiangyi Zhu,Hao Ren,Zeping Wang,Feng Zhang,Xiandong Li,Lu-Qi Tao,Han Zhang,Xianping Chen
Industrial production, environmental monitoring, and clinical medicine put forward urgent demands for high-performance gas sensors. Two-dimensional (2D) materials are regarded as promising gas-sensing materials owing to their large surface-to-volume ratio, high surface activity, and abundant surface-active sites. However, it is still challenging to achieve facilely prepared materials with high sensitivity, fast response, full recovery, and robustness in harsh environments for gas sensing. Here, a combination of experiments and density functional theory (DFT) calculations is performed to explore the application of tellurene in gas sensors. The prepared tellurene nanoflakes via facile liquid-phase exfoliation show an excellent response to NO2 (25 ppb, 201.8% and 150 ppb, 264.3%) and an ultralow theory detection limit (DL) of 0.214 ppb at room temperature, which is excellent compared to that of most reported 2D materials. Furthermore, tellurene sensors present a fast response (25 ppb, 83 s and 100 ppb, 26 s) and recovery (25 ppb, 458 s and 100 ppb, 290 s). The DFT calculations further clarify the reasons for enhanced electrical conductivity after NO2 adsorption because of the interfacial electron transfer from tellurene to NO2, revealing an underlying explanation for tellurene-based gas sensors. These results indicate that tellurene is eminently promising for detecting NO2 with superior sensitivity, favorable selectivity, an ultralow DL, fast response-recovery, and high stability.
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高影响因子
Advanced Science
·
2020
·Vol. 7
·期 11
·1903493
·
IF 15.84
Sihui Li,Jiwu Xin,Abdul Basit,Qiang Long,Suwei Li,Qinghui Jiang,Yubo Luo,Junyou Yang
Lead-free chalcogenide SnTe has been demonstrated to be an efficient medium temperature thermoelectric (TE) material. However, high intrinsic Sn vacancies as well as high thermal conductivity devalue its performance. Here, β-Zn 4 Sb 3 is incorporated into the SnTe matrix to regulate the thermoelectric performance of SnTe. Sequential in situ reactions take place between the β-Zn 4 Sb 3 additive and SnTe matrix, and an interesting “core–shell” microstructure (Sb@ZnTe) is obtained; the composition of SnTe matrix is also tuned and thus Sn vacancies are compensated effectively. Benefitting from the synergistic effect of the in situ reactions, an ultralow κ lat ≈0.48 W m −1 K −1 at 873 K is obtained and the carrier concentrations and electrical properties are also improved successfully. Finally, a maximum ZT ≈1.32, which increases by ≈220% over the pristine SnTe, is achieved in the SnTe-1.5% β-Zn 4 Sb 3 sample at 873 K. This work provides a new strategy to regulate the TE performance of SnTe and also offers a new insight to other related thermoelectric materials.
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Nature Communications
·
2020
·Vol. 11
·期 1
·1-6
·
IF 12.121
Dong Zhuoya,Ma Yanhang
Handedness or chirality determination is a challenging and important topic in various fields including chemistry and biology, as two enantiomers have the same composition and mirror symmetry related structures, but might show totally different activities and properties in enantioselective separations, catalysis and so on. However, current methods are unable to reveal the handedness locally of a nanocrystal at the atomic-level in real-space imaging due to the well-known fact that chiral information is lost in a two-dimensional projection. Herein, we present a method for handedness determination of chiral crystals by atomic-resolution imaging using Cs-corrected scanning transmission electron microscopy. In particular, we demonstrate that enantiomorphic structures can be distinguished through chirality-dependent features in two-dimensional projections by comparing a tilt-series of high-resolution images along different zone axes. The method has been successfully applied to certify the specific enantiomorphic forms of tellurium, tantalum silicide and quartz crystals, and it has the potential to open up new possibilities for rational synthesis and characterization of chiral crystals.
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Optical Materials Express
·
2020
·Vol. 10
·期 4
·1072-1082
·
IF 3.064
Qianhang Luo,Guowu Tang,Guowu Tang,Guowu Tang,Min Sun,Min Sun,Guoquan Qian,Zhenguo Shi,Qi Qian,Qi Qian,Qi Qian,Qi Qian,Zhongmin Yang,Zhongmin Yang,Zhongmin Yang,Zhongmin Yang
Tellurium (Te) semiconductor core optical fibers with silicate glass cladding were drawn by the molten core method. The as-drawn precursor fiber has a large core diameter of about 123 µm, which was found to be polycrystalline. What is more, a Bridgman-type fiber postprocessing technique was constructed and used for the first time to anneal the polycrystalline Te semiconductor core optical fibers. The Te core in precursor fiber was melted and recrystallized to single crystal Te with c-axis orientation parallel to fiber axis, which was confirmed by X-ray diffraction, single crystal X-ray diffraction, micro-Raman spectra, and transmission electron microscope measurement results. Enhanced conductivities were observed in single crystal Te semiconductor core optical fibers under illuminated and stress states, respectively. This work demonstrates that the Bridgman-type fiber postprocessing technique could be an effective way to fabricate single crystal semiconductor core optical fibers with large core diameters (∼ 100 µm) and long lengths (a few centimeters).
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MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 6
·1-7
·
IF 6.232
Tian Li,Wu Kexin,Hu Yue,Wang Yue,Zhao Yingjie,Chen Ruizhan,Lu Juan
An electrochemiluminescence (ECL) nanoprobe was fabricated for the determination of clenbuterol (CLB). A molecularly imprinted polymer (MIP) film was coated on the surface of the glassy carbon electrode modified with CdTe-doped multiwall carbon nanotubes. The MIP film with CLB as the template molecule improves the selectivity of the nanoprobe, CdTe is used as ECL signal amplifier, and MWCNT works as the carrier. The ECL intensity is altered by elution and reabsorption of CLB. The possible reaction mechanism and experimental parameters of the nanoprobe are discussed. Under optimized conditions, the quenched ECL intensity and the CLB concentration have a linear relationship in the range 2.3 × 10 −9 to 1.5 × 10 −5 mol·L −1 , and the detection limit is 1.0 × 10 −9 mol·L −1 (S/ N = 3). The nanoprobe was successfully applied to the determination of CLB in pork samples.
Schematic representation of the molecularly imprinted electrochemiluminescence nanoprobe based on complexes consisting of CdTe and multiwall carbon nanotube used to determinate clenbuterol.
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CHEMICAL ENGINEERING JOURNAL
·
2020
·
IF 10.652
Hengyang Wang,Xiaofang Liu,Bin Zhang,Lisi Huang,Meiling Yang,Xiang Zhang,Hong Zhang,Guoyu Wang,Xiaoyuan Zhou,Guang Han
Binary silver chalcogenides (Ag 2 X, X = S, Se, Te) are a group of intriguing thermoelectric materials. When utilised for thermoelectrics, however, the syntheses of these chalcogenides commonly require energy-intensive, high-temperature melting-annealing processes. Herein, we have developed a general surfactant-free and scalable solution synthesis strategy to nano/micro-particles of binary silver chalcogenides, which requires neither high temperature nor long reaction duration. The chalcogenide particles were spark plasma sintered into pellets with porous structures. By modifying the Ag + /X 2− molar ratios in the solution precursors from 2:1 to 2:1.1, the thermoelectric properties of the pellets have been effectively optimised, leading to maximum ZT values of 0.84 at 380 K for Ag 2 Se, 0.59 at 650 K for Ag 2 Te and 0.27 at 540 K for Ag 2 S that are comparable to those of samples fabricated by other synthetic methods, such as melting and annealing. This study provides a general surfactant-free solution approach to binary silver chalcogenide nano/micro-materials with tuneable thermoelectric properties.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2020
·
IF 3.232
Meiling Ding,Kun Wang,Min Fang,Weiju Zhu,Longchao Du,Cun Li
Mercaptopropionic acid (MPA) capped CdTe quantum dots (MPA-CdTe QDs) were synthesized in aqueous medium by hydrothermal method , which modified by Fe 3+ could be used as a fluorescent probe to detect ascorbic acid (AA). MPA-CdTe QDs fluorescence probe could be used as successive sensor for metal ions and AA with “on-off-on” process. The fluorescence of QDs was quenched after adding Fe 3+ to MPA-CdTe QDs. Then, the fluorescence of the Fe 3+ @MPA-CdTe QDs can be sensitively turned on by AA to give an “on–off–on” fluorescence response according to the oxidation–reduction between Fe 3+ and AA. There was a linear relationship between fluorescence intensity quenching value and the concentration of Fe 3+ in the range of 2–10 μM since Fe 3+ sensitively reacted with CdTe QDs. The linear detection range for AA was 0.1–1 μM with a limit of detection of 6.6 nM. The principle is proved by fluorescence emission spectroscopy, nuclear magnetic resonance spectroscopy. The proposed method is successfully used to detect the AA in human plasma sample.
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