JOURNAL OF COORDINATION CHEMISTRY
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2014
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IF 2.212
Xiao-Li Tang,Ai-Qing Ma,Guo-Qiang Cai,Long-Guan Zhu
Three complexes with same components, PdII, 2-sulfobenzoate and 1,10-phenanthroline, [Pd(phen)2]⋅2(2-Hsb) (1), [Pd(phen)2](2-Hsb)⋅(2-Hsb)⋅2H2O (2), and [Pd(phen)2]⋅[Pd(phen)(2-sb)2]⋅6H2O (3), where 2-H2sb is 2-sulfobenzoic acid and phen is 1,10-phenanthroline, were synthesized and characterized by IR spectra, elemental analyses, thermogravimetric analyses, UV–vis absorption spectra and powder X-ray analysis. Single X-ray crystal structural analyses showed that 1 and 2 are ionic species, while 3 is a dimer through weak bonding interactions. In 1 and 2, 2-Hsb− ligands are partly deprotonated and it is fully deprotonated in 3. In 2 and 3 there are hydrogen bonds and π–π interactions. Extended hydrogen bonding structures for 2 and 3 are 1-D and 3-D architectures, respectively. The oxidation of methyl phenyl sulfide by 1-3 as homogeneous catalysts gave high conversion and selectivity in methanol. The addition of 2-sulfobenzoic acid in the catalytic reaction further promotes the conversion.
研究领域:
化学
·
材料科学
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DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2013
·Vol. 130
·期 2
·1399-1405
·
IF 1.395
Jiajie Wu,Jiachun Feng
A novel hindered amine ligand, mono-2,2,6,6-tetramethyl-4-piperidyl-succinate (MTPS), has been designed to chelate europium(III) ion with 1,10-phenanthroline (Phen) as a coligand to prepare polymer photostabilizer. The luminescent property of the stabilizer and its efficiency of protecting polymer matrix from photodegradation have also been investigated. Under UV excitation, the stabilizer has red light emission in both ethanol solution and polypropylene (PP) matrix. The PP sheets containing the stabilizer display significantly improved photostability, which may be attributed to MTPS which scavenges radical, as well as Phen which makes the complex dissipate the absorbed ultraviolet light in a harmless manner. These preliminary results demonstrate that the introduction of the stabilizer can endow polymer matrices not only excellent photoluminescent properties but also improved photostability. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 130: 1399-1405, 2013
研究领域:
材料科学
·
化学
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DOI
高影响因子
MICROCHIMICA ACTA
·
2013
·Vol. 180
·期 5
·431-436
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IF 3.434
Chen Hongxia,Liu Feng,Koh Kwangnak,Lee Jaebeom,Ye Zonghuang,Yin Tingting,Sun Lizhou
We show that the antigen CFP-10 (found in tissue fluids of tuberculosis patients) can be used as a marker protein in a surface-plasmon resonance (SPR) based method for early and simplified diagnosis of tuberculosis. A sandwich SPR immunosensor was constructed by immobilizing the CFP-10 antibody on a self-assembled monolayer on a gold surface, this followed by blocking it with bovine serum albumin. Following exposure of the sensor surface to a sample containing CFP-10, secondary antibody immobilized on nickel oxide nanoparticles are injected which causes a large SPR signal change. The method has a dynamic range from 0.1 to around 150 ng per mL of CFP-10, and a detection limit as low as 0.1 ng per mL. This is assumed to be due to the high amplification power of the NiO nanoparticles.
Schematic diagram of sensor chip configuration (left) and SPR study based on amplification strategy with NiO nanoparticles (right).
研究领域:
医学诊断
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生物传感
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纳米技术
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产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2018
·
IF 5.667
Liaojing Huang,Liu Yang,ChuanChao Zhu,Hanmei Deng,Guangpeng Liu,Yali Yuan
It is of great significance to explore reliable and sensitive methods for the trace detection of lead ions (Pb 2+ ), which may cause serious adverse effect to human health. Herein, we proposed a methylene blue (MB) sensitized signal-on photoelectrochemical (PEC) biosensor with 3,4,9,10-perylene tetracarboxylic acid (PTCA) film as photoelectric material for highly sensitive Pb 2+ detection. First, PTCA was modified on the electrode surface, manifesting wonderful film-forming property and acquiring a satisfactory initial PEC signal. Afterward, Pb 2+ -dependent DNAzyme modified on electrode was cleaved by target Pb 2+ , followed by hybridizing MB assembled 3D DNA networks with the exposed Pb 2+ catalytic strand. Significantly, in the presence of sensitizer MB, the PEC signal of PTCA was extraordinarily increased and the designed biosensor performed a high sensitivity with a detection limit down to 0.03 pM. Therefore, with enzyme-free assembly of MB embedded 3D DNA networks, this dye-sensitized strategy exhibited effective and uncomplicated amplification technology for Pb 2+ detection.
研究领域:
分析化学
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环境科学
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生物传感技术
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产品关联
DOI
高影响因子
JOURNAL OF CATALYSIS
·
2020
·
IF 7.888
Lei Liu,Han Gao,Shu-Qing Yang,Xiao-Chao Chen,Yong Lu,Ye Liu,Fei Xia
The one-pot tandem hydroformylation-reduction to synthesize alcohols from olefins is in great demand but suffering from low yields, poor selectivity and harsh condition. Herein, 1,10-phenanthroline ( L1 ) modified Ir-catalyst proved to exhibit multiple catalysis in terms of FA dehydrogenation, hydroformylation of olefins, and transfer hydrogenation of aldehydes to accomplish the tandem hydroformylation-transfer hydrogenation of olefins with formic acid (FA) as hydrogen source, as the result of 52–70% yields for the target alcohols and the corresponding formate esters (obtained upon esterification of the alcohol with FA). In this sequence, only the use of FA with trans - and cis -conformers could fulfill the reduction of aldehydes to the alcohols through transfer hydrogenation as well as greatly depress hydrogenation of the olefin, which universally occurred in the high pressured gaseous H 2 . Both the in situ FT-IR spectroscopic analysis and the DFT-calculations verified that, over L1 -[Ir(COD)Cl] 2 catalyst, cis -FA serving as the hydride-ligand was responsible for the efficient dehydrogenation of FA to release H 2 along with CO 2 , and trans- FA serving as the carbonyl O-containing ligand corresponded to the transfer hydrogenation of the aldehydes to the alcohols under the same catalytic conditions.
研究领域:
有机化学
·
催化化学
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DOI
高影响因子
Small
·
2024
·Vol. 20
·期 52
·2407715
·
IF 13
Chang Li,Xinyu Guo,Wenjun Deng,Na Shen,Yi Zhou,Yan Chen,Rui Li
Aqueous iron-ion batteries with reversible storage of Fe 2+ have undergone rapid development in recent years. Consistently throughout these studies, metallic iron is selected as the anode material. However, the large overpotential (250 mV) associated with the plating/stripping process of iron in aqueous solutions leads to unsatisfactory energy efficiency of the battery, although high capacity and Coulomb efficiency can be achieved. Herein, an iron-free anode material, 9,10-anthraquinone (AQ) is proposed in aqueous iron-ion batteries, which shows a low reaction potential and minimal polarization during storing iron ions. The organic anode exhibits favorable specific capacity of 106 mAh g −1 at 0.5 A g −1 and excellent cycling stability (92.6% retention after 500 cycles). In addition, an aqueous full iron-ion battery is constructed using AQ as the anode and 9,10-phenanthraquinone (PQ) as the cathode. The full battery demonstrates an enhanced energy efficiency of 72%, which is 206% higher than that of metal iron anode, and shows excellent cycling stability and Coulombic efficiency. This work provides a viable route to overcome the high polarization of metallic iron anode and promote the development of aqueous iron-ion batteries.
研究领域:
材料科学
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电化学
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产品关联
DOI
PubMed
高影响因子
Small
·
2019
·Vol. 16
·期 3
·1906462
·
IF 10.856
Pengfei Sun,Panxing Bai,Zifeng Chen,Hai Su,Jixing Yang,Kang Xu,Yunhua Xu
Lithium primary batteries are still widely used in military, aerospace, medical, and civilian applications despite the omnipresence of rechargeable Li-ion batteries. However, these current primary chemistries are exclusively based on inorganic materials with high cost, low energy density or severe safety concerns. Here, a novel lithium-organic primary battery chemistry that operates through a synergetic reduction of 9,10-anthraquinone (AQ) and fluoroethylene carbonate (FEC) is reported. In FEC-presence, the equilibrium between the carbonyl and enol structures is disabled, and replaced by an irreversible process that corresponds to a large capacity along with methylene and inorganic salts (such as LiF, Li 2 CO 3 ) generated as products. This irreversible chemistry of AQ yields a high energy density of 1300 Wh/(kg of AQ) at a stable discharge voltage platform of 2.4 V as well as high rate capability (up to 313 mAh g −1 at a current density of 1000 mA g −1 ), wide temperature range of operation (−40 to 40 °C) and low self-discharge rate. Combined with the advantages of low toxicity, facile and diverse synthesis methods, and easy accessibility of AQ, Li-organic primary battery chemistry promises a new battery candidate for applications that requires low cost, high environmental friendliness, and high energy density.
研究领域:
材料科学
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电化学
·
能源技术
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产品关联
DOI
PubMed
高影响因子
LASERS IN SURGERY AND MEDICINE
·
2020
·Vol. 53
·期 5
·684-694
·
IF 3.02
Qiming Ma,Donghong Liu,Renyan Gong,Shaofeng Chen,Fang Fang,Yuehong Zhuang
Background and Objectives Vasospasm is a thorny problem often encountered in microvascular surgery that seriously threatens the survival of vascularized tissue transfers. This investigation is dedicated to establishing a model of vasospasm and to evaluating the antispasmodic efficacy of 10 pharmacologic agents. Study Design/Materials and Methods Eighty Sprague–Dawley rats were used. After anesthesia and depilation, the femoral neurovascular bundle was exposed, and a pair of microsurgical forceps were used to trigger vasospasm of the femoral vessels by blunt dissection. Then, 10 pharmacological agents, namely, prostaglandin E1, sodium nitroprusside, magnesium sulfate, papaverine, normal saline, phentolamine, verapamil, 2% lidocaine hydrochloride, amrinone, and 12% lidocaine hydrochloride, were dripped to the femoral vessels, after which laser speckle contrast imaging was used to collect perfusion images, acquiring the perfusion and the inner caliber of the femoral vessels at multiple timepoints. Furthermore, blood perfusion and the time consumed to escape vasospasm and reach hyperperfusion in each group were calculated. The difference of spasmolytic efficacy among the agents was statistically analyzed by one-way analysis of variance. Results There was a significant difference in antispasmodic ability among the 10 agents ( P < 0.001). 10% magnesium sulfate and 12% lidocaine were distinguished among the 10 agents in resolving the vasospasm. 10% magnesium sulfate demonstrated the best antispasmodic potency, which enabled the shortest time consumed for vessels to escape spasm and reach hyperperfusion. 12% lidocaine ranked second in efficacy, demonstrating a similar effect except that it could not propel the femoral vein to a state of hyperperfusion. For the remaining agents, the time consumed for the artery to escape spasm was all significantly shortened when compared with normal saline ( P < 0.001). For the venous spasm, all agents except prostaglandin E1 could significantly shorten the time consumed for the vein to escape spasm ( P < 0.001). Conclusions In terms of resolving mechanically induced vasospasm, 10% magnesium sulfate is the best antispasmodic, followed by 12% lidocaine. Lasers Surg. Med. © 2020 Wiley Periodicals LLC
研究领域:
药理学
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显微血管外科
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生物医学工程
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实验动物研究
✓ 已验证
DOI
PubMed
高影响因子
Acta Biomaterialia
·
2021
·
IF 8.947
Qian Huang,Xun Liu,Haiyang Wang,Xiangrui Liu,Qianzhi Zhang,Ke Li,Yu Chen,Qian Zhu,Youqing Shen,Meihua Sui
Clinical development of 7-ethyl-10‑hydroxy-camptothecin (SN38), the active metabolite of irinotecan (CPT-11), is hindered by its insolubility and poor stability. Another obstacle is that tumors could become resistant to SN38/CPT-11 through multiple mechanisms involving breast cancer resistance protein (BCRP). Herein one of the most potent and selective BCRP inhibitors, Ko143, is encapsulated into a recently constructed prodrug PEG-S-S-SN38 displaying a high and fixed drug loading, multiple intratumoral stimuli (oxidative stress, GSH and esterase)-responsive drug release and significant in vitro and in vivo superiorities over CPT-11. The obtained “combo” for simultaneous delivery of SN38 and Ko143, named as [email protected] , has a high SN38 loading efficacy (14.85 wt.%) and a good Ko143 encapsulation efficacy (3.79%). Through generating panels of human colorectal cancer models expressing altered levels of BCRP via lentiviral transfection and CRISPR-Cas9, characteristics of different drug formulations are carefully evaluated. Impressively, [email protected] nanoparticles effectively reverse chemoresistance to CPT-11 (resistance index dropping from ∼274.00–456.00 to ∼1.70–4.68) and PEG-S-S-SN38 (resistance index dropping from ∼5.83–14.00 to ∼1.70–4.68) in three BCRP-overexpressing cancer cell lines. More importantly, reversal of BCRP-mediated chemoresistance to CPT-11 ( P values lower than 0.001–0.0001) and PEG-S-S-SN38 ( P values lower than 0.01–0.001) by [email protected] nanoparticles are further confirmed with two panels of colorectal cancer xenograft models in vivo . As the first nano-formulation of Ko143 and the first systemic co-delivery vehicle of SN38/CPT-11 and a BCRP inhibitor, [email protected] provides a new approach for resolving the bottlenecks for clinical translation of SN38 and numerous “chemosensitizers” like Ko143, and exhibits promising applicability in precision cancer medicine. Statement of significance To resolve the bottlenecks in clinical application of anticancer agents SN38/CPT-11 and the most potent breast cancer resistant protein (BCRP) inhibitor Ko143, a “combo” nanotherapeutic simultaneously delivering SN38 and Ko143 was constructed and named as [email protected] By generating panels of colorectal cancer models, we demonstrate that [email protected] nanoparticles effectively and selectively reversed BCRP-mediated tumor resistance to SN38/CPT-11 in vitro and in vivo . As the first nano-formulation of Ko143 and the first systemic co-delivery vehicle of SN38/CPT-11 and a BCRP inhibitor, [email protected] provides a new strategy for clinical development of SN38 and numerous “chemosensitizers”, and exhibits promising applicability in precision cancer medicine. Panels of cancer cell lines established here provides a useful platform for BCRP- and cancer-related research and technology development.
研究领域:
肿瘤学
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药学
·
纳米技术
·
分子生物学
✓ 已验证
DOI
PubMed
高影响因子
Science Advances
·
2024
·Vol. 10
·期 40
·
IF 11.7
Zhenliang Hu,Qiang Fu,Junpeng Lu,Yong Zhang,Qi Zhang,Shixuan Wang,Zhexing Duan,Yuwei Zhang,Xiaoya Liu,Qiang Pan,Guangsheng Jiang,Tong Yang,Xu Han,Yutian Yang,Tianqi Liu,Tao Tao,Wenhui Wang,Bei Zhao,Xueyong Yuan,Dongyang Wan,Yanpeng Liu,Yumeng You,Peng Zhou,Hongwei Liu,Zhenhua Ni
The construction of miniaturized light-emitting diodes (LEDs) with high external quantum efficiency (EQE) at room temperature remains a challenge for on-chip optoelectronics. Here, we demonstrate microsized LEDs fabricated by a dry-transfer van der Waals (vdW) integration method using typical layered Ruddlesden-Popper perovskites (RPPs). A single-crystalline layered RPP nanoflake is used as the active layer and sandwiched between two few-layer graphene contacts, forming van der Waals LEDs (vdWLEDs). Strong electroluminescence (EL) emission with a low turn-on current density of ~20 pA μm−2 and high EQE exceeding 10% is observed at room temperature, which sets the benchmark for the EQE of vdWLEDs ever recorded. Such efficient EL emission is attributed to the inherent multiple quantum well structure and high photoluminescence quantum yield (~35%) of RPPs and a low charge injection barrier of ~0.10 eV facilitated by the Fowler-Nordheim tunneling mechanism. These findings promise a scalable pathway for accessing high-performance miniaturized light sources for on-chip optical optoelectronics.
研究领域:
材料科学
·
光电子学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CARBON
·
2026
·
IF 12.7
Xiaoqi Mao,Qichao Wei
The conventional approach of enhancing the strength of titanium alloys and their composites through mechanical processing to induce dislocations often leads to compromised ductility. In recent years, structural design strategies have stimulated the exploration of the material community towards deformation mechanisms and their impact on mechanical properties. Herein, we introduce the {10 1 ‾ 2} twinning to the B@Gr/TC4 composites, which were synthesized using ball milling, spark plasma sintering, hot rolling, and heat treatment processes. These composites are reinforced by in-situ formed TiC and TiB hybrid phases, achieving a high ultimate tensile strength (UTS) of 1424 MPa and fractured elongation (FE) of 13%, which are superior to those of TC4 alloy (with its UTS of 984 MPa and FE of 12%) and Gr/TC4 composite (with its UTS of 1325 MPa and FE of 12%). The enhanced strength of the composite is primarily attributed to the grain refinement and dislocation strengthening effects contributed by the high percentage of small-angle grain boundaries pinned by TiC and TiB hybrid phases. Furthermore, the twinning-induced strain softening effect is identified as the key mechanism for maintaining exceptional ductility. This study provides an effective structural strategy to simultaneously improve the strength-ductility of Ti matrix composites.
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产品关联
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2026
·
IF 19.9
Biao Li,Juanjuan Peng,Zhouyan Chang,Yaqing Yang,Fusong Chen,Zeya Yang,Mingmin Cao,Qian Xu,Awu Zhou,Yibo Dou,Jun Lu,Jingbin Han
The rapid and efficient separation of nanoscale targets in liquid matrices presents a critical yet formidable challenge. Polyamide (PA) membranes, while recognized as the benchmark for industrial-scale nanoscale separation, face ongoing limitations in performance optimization. Although advances in nanomaterials have enabled breakthroughs in PA membrane performance, scalable production remains hindered by integration challenges. Here, we present a scalable strategy to fabricate ultra-thin (<10 nm) nanofiltration membranes by constructing a layered double hydroxide (LDH) nanoplate-enhanced piperazine (PIP) intermediate layer via interfacial polymerization (IP) with trimesoyl chloride. Hydrogen-bond networks between PIP and LDH, combined with ordered water structures induced by LDH hydroxyl groups, restricted PIP diffusion, thus yielding ultrathin membranes with high ionization. Moreover, the rough LDH intermediate layer promoted a rougher membrane surface, enhancing the effective filtration area and permeability. The optimized membranes achieved a pure water permeance of 89.6 ± 3.5 L m −2 h −1 bar −1 and a Na 2 SO 4 rejection rate of 95.7%, achieving one of the best-reported levels. Leveraging the accessibility of LDH colloids and the scalable fabrication process, this strategy enables the production of large-area membranes via spraying and IP, making it highly promising for purifying and recovering antibiotics.
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DOI
高影响因子
危险品化学品经营许可证（带存储）