JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2011
·
IF 2.089
Xue Wang,Jianming Pan,Wei Guan,Jiangdong Dai,Xiaohua Zou,Yongsheng Yan,Chunxiang Li,Wei Hu
A simple method for selective recognition of 3-chlorophenol (3-CP) from aqueous solution has been developed using a surface molecularly imprinted polymer (MIP) as sorbent. Characterization of the obtained MIP was achieved by Fourier transform infrared spectroscopy (FTIR). Kinetic, thermodynamic, dynamic adsorption, and selectivity experiments were investigated in this study. Kinetic experimental data were well-described by the pseudosecond-order kinetic model. The obtained Arrhenius activation energy Ea from the kinetic data indicated a physisorption mechanism, and the negative values of ΔHo demonstrated that the adsorption of 3-CP onto MIP was exothermic. Equilibrium experimental data of MIP fitted the Langmuir isotherm well. The MIP showed outstanding affinity toward 3-CP in aqueous solution, and the optimum pH value for binding has been found around the neutral range. When methanol was used as eluent, the adsorbed 3-CP eluted easily from MIP. The total dynamic capacity of the imprinted sorbent was calculated to be 1137.58 mg·g–1. The breakthrough of 3-CP started after 60 mL, and the breakthrough capacity was 756.8 mg·g–1. Meanwhile, selectivity experiments demonstrated that MIP showed high affinity to target molecules over competitive CPs (2,6-dichlorophenol and 2,4,6-trichlorophenol).
研究领域:
环境科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2015
·Vol. 39
·期 8
·5898-5901
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IF 3.086
Xiao Lian,Bing Yan
Both metal organic frameworks (IRMOF-3) and SBA-15 have been used to assemble novel photofunctional multi-component lanthanide hybrid materials (Ln-SBA-15-Si-IRMOF-3, Ln = Eu, Tb, Nd, and Yb), whose luminescent color can be tuned by adjusting the composition.
研究领域:
材料科学
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光学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2017
·
IF 4.529
Lei Zhou,Zhiqiang Xiong,Wei Liu,Liqiang Zou
Gentisic acid and cyanidin-3-O-glucoside are important bioactive polyphenols which are widely distributed in many fruits and cereals. In this work, kinetic study, spectral analysis and computational simulation were used to compare the inhibitory effects and inhibition mechanisms of gentisic acid and cyanidin-3-O-glucoside on mushroom polyphenoloxidase (PPO). The inhibitory effect of cyanidin-3-O-glucoside on PPO was much stronger than that of gentisic acid. Gentisic acid inhibited PPO in a reversible mixed-type manner while cyanidin-3-O-glucoside was an irreversible inhibitor. Gentisic acid and cyanidin-3-O-glucoside made the thermal inactivation of PPO easier, and induced apparent conformational changes of PPO. Compared with gentisic acid, cyanidin-3-O-glucoside had stronger effects on the thermal inactivation and conformation of PPO. Molecular docking results revealed gentisic acid bound to the active site of PPO by hydrogen bonding, π–π stacking and van der Waals forces. However, cyanidin-3-O-glucoside might irreversibly interact with the Met or Cys in PPO by covalent bonds.
研究领域:
生物化学
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食品科学
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产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 6
·1-16
·
IF 5.3
Li Guiyin,Guo Fei,Liang Jianlu,Wan Bingbing,Liang Jintao,Zhou Zhide
A new sandwich-type electrochemical biosensing platform was developed by gold @polyphthalenediamine nanohybrids (AuNP@PoPD) as the sensing platform and phosphorus doped reduced graphene oxide-hemin-palladium nanoparticles (PrGO-Hemin-PdNP) as the signal amplifier for phosphatidylinositol proteoglycan 3 (GPC3). AuNP@PoPD, co-electrodeposited into the screen printed electrode with high conductivity and stability, is dedicated to assembling the primary GPC3 aptamer (GPC3 Apt ). The second GPC3 Apt immobilized on the high conductivity and large surface area of PrGO-Hemin-PdNP was utilized as an electrochemical signal reporter by hemin oxidation (PrGO-Hemin-PdNP-GPC3 Apt ). In the range 0.001–10.0 ng/mL, the hemin oxidation current signal of the electrochemical aptasensor increased log-linearly with the concentration of GPC3, the lowest detection limit was 0.13 pg/mL, and the sensitivity was 2.073 μA/μM/cm 2 . The aptasensor exhibited good sensing performance in a human serum sample with the relative error of 4.31–8.07%. The sandwich sensor showed good selectivity and stability for detection GPC3 in human serum samples, providing a new efficient and sensitive method for detecting HCC markers. Graphical Abstract
研究领域:
生物医学工程
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分析化学
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肿瘤学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
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2020
·
IF 4.3
Yi Cheng,Jilin Zhang
Excessive phosphate in wastewater can cause eutrophication of water body, which will worsen the ecological environment and threaten human health and biological life safety. Adsorption of phosphate is the most effective way to remove phosphate, and efficient adsorbent is the key. Amorphous La(OH) 3 has been deemed as a potential phosphate adsorbent on account of high adsorption capacity and environmentally friendly property. However, it also shows some disadvantages such as easy agglomeration, poor water dispersion. In this study, UiO-66-NH 2 was used as carrier to load amorphous lanthanum hydroxide as an adsorbent for phosphate removal. The adsorbent (UiO-66-NH 2 @La(OH) 3 , ULCs) has good water dispersibility and it is easy to be separated and recovered. At the same time, the maximum phosphate adsorption capacity can reach 140.7 mg P/g. The adsorption process accords with pseudo second order kinetic model and Freundlich isotherm model. The thermodynamic results showed that the adsorption process was spontaneous and endothermic. In addition, in the presence of coexisting anions (such as Cl − , SO 4 2− , NO 3 − ), it also exhibited high selectivity and phosphate removal efficiency. Meanwhile, the adsorption capacity keeps at a high level in the range of pH 3–11. By the merit of above-mentioned properties, the prepared material is expected to be an ideal candidate for phosphate removal from contaminated water.
研究领域:
环境科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2020
·
IF 10.652
Ihtisham Ul Haq,Shen Hui Li,Hong-Gang Zhen,Rehan Khan,Ao-Shuai Zhang,Zhi-Ping Zhao
For separating 1, 3-butadiene (BD) from BD/N 2 mixture, among numerous studied metal–organic frameworks-based adsorbents, Ni-ZIF-8 was comparatively selected here based on intelligent gravimetric analysis, simulation studies, facile synthesis, and very good IAST selectivity. Experimental results showed good butadiene uptake capacity of Ni-ZIF-8 of 7.41 mol/kg, which is 42% higher than pure ZIF-8. Additionally, Ni-ZIF-8 exhibits IAST selectivities of 2826 and 3302 at 0.1 bar, at 25 and 45 °C respectively, for 20% BD/N 2 adsorption. The molecular simulation results showed that Ni-ZIF-8 has binding energies of 65.25, 9.54 kJ/mol, while ZIF-8 has 56.07, 15.03 kJ/mol for butadiene, and nitrogen, respectively. This strongly supported the experimental results. To the best of our knowledge, Ni-ZIF-8 showed the best working capacity of 5.91 mol/kg for butadiene among all the reported adsorbents. Moreover, dynamic adsorption experiments revealed that butadiene could be recovered from BD/N 2 mixtures at room temperature, suggesting great potential for industrial BD/N 2 separation.
研究领域:
材料科学
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化学工程
✓ 已验证
产品关联
DOI
高影响因子
Food Science & Nutrition
·
2018
·Vol. 6
·期 8
·2020-2027
·
IF 1.521
Hong Fu,Mengqi Li,Ruimin Ni,Yangming Martin Lo
Two different fish oil preparations, namely triglycerides and ethyl esters containing, respectively, 30.02% and 74.38% of omega-3 fatty acids, were employed as the substrates for transesterification. Catalyzed by immobilized lipase using imidazolium-based ionic liquid systems, the total content of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in the resulting triglyceride reached 63.60% when 4% hydrophobic ionic liquid was used, which was 11.74% higher than that of the triglyceride produced in a solvent-free reaction system. The activation energy of the product (triglyceride-type fish oil) was 173.64 KJ mol −1 , which was not significantly different from that of the commercial ethyl ester-type fish oil, so were the other thermal oxidative kinetic parameters. The kinetic parameters depicting the thermal and oxidative stability of the fish oil product provide the basis for industrial processing, storage, and applications.
研究领域:
生物化学
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可持续生产
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食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ORGANIC & BIOMOLECULAR CHEMISTRY
·
2014
·Vol. 13
·期 2
·601-611
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IF 3.487
Xiong-Li Liu,Bo-Wen Pan,Wen-Hui Zhang,Chao Yang,Jun Yang,Yang Shi,Ting-Ting Feng,Ying Zhou,Wei-Cheng Yuan
A highly efficient and environmentally benign method for the synthesis of oxindoles featuring two contiguous quaternary carbon centers via an aldol reaction starting from various 3-substituted oxindoles has been established. A wide variety of such featured multi-substituted 1,3-indandione ring-fused 3-oxindole scaffolds were obtained smoothly in good yields (up to 98%) employing the most green of solvents, namely water, as reaction medium. Furthermore, their biological activity has been preliminarily demonstrated by in vitro evaluation against human prostate cancer cells PC-3, human lung cancer cells A549 and human leukemia cells K562 by MTT-based assays, using the commercially available standard drug, cisplatin, as a positive control. Gratifyingly, compounds 3s, 3u, 3y and 3c′ exhibited the best levels of in vitro inhibitory activity against human leukemia cells K562, which were almost 2.0, 2.8, 2.5 and 2.2 times, respectively, the activity of the positive control, cisplatin. Compound 3y had 2.7 times the activity of the positive control, cisplatin, against PC-3 cancer cells, and 3s, 3u and 3c′ showed levels of in vitro inhibitory activity against PC-3 cancer cells that were comparable to that of cisplatin. Compounds 3s, 3u and 3y had good inhibitory ability against human lung cancer cells A549. The results indicated that 1,3-indandione ring-fused 3-oxindole analogs may be useful leads for further biological screenings.
研究领域:
有机化学
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药物化学
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肿瘤学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHEMICAL RESEARCH
·
2020
·
IF 0.593
Mingguang Zhang,Zhongbao Bi,Yunyun Wang,Yuxun Zhao,Yang Yang,Yongqiang Zhu,Shifa Wang
A new and practical synthesis of 3-chloro-2,4-difluoro-5-hydroxybenzoic acid, a key intermediate for preparing antimicrobial 3-quinolinecarboxylic acid drugs, is synthesized from 2,4-difluoro-3-chlororobenzoic acid. The protocol involves nitration, esterification, reduction of NO2, diazotization, and hydrolysis with a 70% overall yield. The structures of the synthesized compounds are determined by infrared spectroscopy, nuclear magnetic resonance spectroscopy, and high-resolution electrospray ionization mass spectrometry. The advantages of this developed synthetic strategy include an improved overall yield and readily controllable reaction conditions.
研究领域:
有机化学
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药物化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF LOSS PREVENTION IN THE PROCESS INDUSTRIES
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2015
·
IF 1.406
L. Zhang,W.D. Yu,X.H. Pan,J.J. Fang,M. Hua,F.M. Chen,J.C. Jiang
The exothermic oxidation of 3-methylpyridine with hydrogen peroxide was analyzed by Reaction Calorimeter (RC1e) in semi-batch operation. Heat releasing rate and heat conversion were studied at different operating conditions, such as reaction temperature, feeding rate, the amount of catalyst and so on. The thermal hazard assessment of the oxidation was derived from the calorimetric data, such as adiabatic temperature rise (ΔT ad ) and the maximum temperature of synthesis reaction (MTSR) in out of control conditions. Along with thermal decomposition of the product, the possibility of secondary decomposition under runaway conditions was analyzed by time to maximum rate (TMR ad ). Also, risk matrix was used to assess the risk of the reaction. Results indicated that with the increase of the reaction temperature, the reaction heat release rate increased, while reaction time and exotherm decreased. With the increase of feeding time, heat releasing rate decreased, but reaction time and exotherm increased. With the amount of the catalyst increased, heat releasing rate increased, reaction time decreased and exothermic heat increased. The risk matrix showed that when the reaction temperature was 70 °C, feeding time was 1 h, and the amount of catalyst was 10 g and 15 g, respectively, the reaction risk was high and must be reduced.
研究领域:
化学工程
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安全科学
✓ 已验证
产品关联
DOI
高影响因子
FOOD SCIENCE AND TECHNOLOGY RESEARCH
·
2021
·
IF 0.668
Zhe Zheng,Mingwu Qiao,Zhongwei Zhang,Chang Li
The effects of three phytosterols (β-sitosterol, stigmasterol, and campesterol) on the formation of 3-monochloropropane-1,2-diol (3-MCPD) esters and the possible mechanism were investigated in this study. Model reaction with 1,2-dipalmitoyl-sn-glycerol (DPG) and sodium chloride as the reacting precursors was adopted to investigate effects of three phytosterols on the formation of 3-MCPD esters. The results showed that three phytosterols exhibited inhibiting activity on the formation of 3-MCPD esters in the model reactions. ESR signal detection indicated that the phytosterols suppressed the formation of free radical in the model reactions. In addtion, 3-chloro-Δ5-cholestenes were detected in the reaction models by using UPLC-APCI-MS. It suggested that phytosterols reacted with chloride and transformed to 3-chloro-Δ5-cholestenes. Therefore, the possible mechanism of phytosterols inhibiting the formation of 3-MCPD esters could be proposed that phytosterols suppressed formation of free radical intermediates in model reactions and competed with DPG for chloride ion to reduce the formation of 3-MCPD esters.
研究领域:
食品科学
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化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
·
2022
·Vol. 103
·期 1
·205-213
·
IF 2.606
Zhao Qian,Yang Wensheng,Zhang Qin,Qiu Liren,Zhou Min,Lu Shengshang,Tao Benfu,Wang Xinhai,Xie Quan,Ruan Yunjun
Sodium super ion conductor (NASICON) structure materials, known for fast diffusion channels for Na + , are promising solid electrolyte materials for sodium-ion batteries (SIBs). However, the high carbon content in the NASICON electrolyte materials originated from the carbothermal reduction (CR) reaction will cause short-circuit and self-discharge of the batteries. Herein, we developed a facile and straightforward two-stage calcining strategy to prepare Na 3 V 2 (PO 4 ) 3 (NVP) with high purity and crystallinity. By precisely controlling the dosage of reducing agent and heat temperature, the purity of NVP can reach 99.97%. Moreover, the NVP film was prepared by the as-synthesized pure NVP powder via fast hot-pressing sinter, whose Vickers hardness is (5.0 ± 0.4) × 10 2 HV and relative density is 99.05%. This study provides a safe and facile strategy to prepare high-purity NVP powder and high-quality NVP films, which is of great significance in exploring NVP as a solid electrolyte for SIBs.
Graphical abstract
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）