MATERIALS CHEMISTRY AND PHYSICS
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2011
·
IF 2.356
Meilan Wang,Tao He,Yanfei Pan,Weiping Liao,Shangzhou Zhang,Wei Du
Hydrolysis of tetrabutyl titanate (TBT) and crystallization from hydrolyzed intermediates were carried out in a simple ternary system including n -octanol, TBT and water. Anatase TiO 2 nanocrystals (NCS) were prepared with precise size control below 10 nm. The hydrolysis rate at different water concentration ( C water ) was evaluated by measuring the induction time before turbidity changing of the synthetic solution. Fourier transform infrared spectrum (FT-IR) and thermogravimetric/differential thermal analysis (TG/DTA) techniques were applied to make clear the composition of hydrolyzed intermediates obtained at different C water . Powder X-ray diffraction (XRD) technique was used to track the crystallization process of TiO 2 NCS. Transmission electron microscopy (TEM), XRD, FT-IR and TG/DTA techniques were used to characterize the particular properties of NCS. The C water controlled mechanism responsible for the slow hydrolysis and crystallization were discussed. Since no other organic capping ligands or rapid injecting techniques were used to limit NCS’ growth and the solvent n -octanol can be easily separated and reused, this simple synthetic process is of green chemistry and has application potential in large-scale preparation of inorganic NCS.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2021
·
IF 7.46
Hui Yue,Jinri Chen,Xu Chen,Xiaoli Wang,Yuting Zhang,Nandi Zhou
Sialic acids (SAs), particularly its most common derivative N-acetylneuraminic acid (Neu5Ac) are involved in many biological processes in vivo . Thus it is of great significance to detect Neu5Ac and trace the sialylation of glycoproteins and other bio-active molecules. Aptamers are molecular elements for bio-recognition with high affinity, which have been widely used in bioanalysis and imaging. However, the ideal aptamers for saccharides have seldom been reported. Magnetic beads (MB)-based SELEX is a commonly used method for screening of aptamers. Herein, three types of MB-based SELEX with different immobilization manners were carried out to systematically study and compare the screening efficiency, which may provide reference for screening of aptamers specific for low-molecular targets. After screening and sequencing, the obtained aptamer sequences were aligned and analyzed, among which three aptamers were selected as candidates. Then, the aptamer ap 3-1 with the highest affinity was optimized according to the results of molecular simulation docking. An optimal aptamer ap 3-1-a with 21 nucleotides (nt) was eventually obtained, with the K d value of 55.71 ± 12.29 nM. To verify the practicability of the aptamer, a fluorescent biosensor for Neu5Ac was constructed employing graphene oxide (GO)-based fluorescence quenching and Neu5Ac-induced fluorescence restoration. The biosensor showed a linear response range within 20−1000 nM. The specificity was verified and the interferents-resistance was validated by detecting Neu5Ac in actual samples. This study may inspire the efficient and universal strategy for screening and application of robust and practicable aptamers for low-molecular targets.
研究领域:
生物化学
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分子生物学
·
分析化学
✓ 已验证
DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2020
·
IF 3.573
Jun Tang,Yali Cao,Fei Ruan,Fengfeng Li,Yangxin Jin,Minh Ngoc Ha,Xinya Han,Qingping Ke
Condensation of 2-amino-phenols with carboxylic acid derivatives has been practically used for the production of benzoxazoles, wherein the homogeneous catalytic system including strong acids and dangerous peroxides is generally employed. Herein, we report the novel approach for controlled synthesis of nitrogen-doped MnOx (denoted as N-MnO2, N-Mn5O8, and N-Mn3O4), by adjusting the heteroatom nitrogen amount, and uncover that the N-MnO2 catalyst as a sustainable and cost-effective heterogeneous catalyst exhibits high catalytic performance for condensation of 2-amino-phenols and o-phenylenediamine with alcohols into the corresponding benzoxazoles and benzimidazole, respectively. The N-MnO2 catalyst displays >99.9% yield for benzoxazole synthesis under room temperature and no decay (10 cycles), compared with the neglect activity (∼0%) for MnO2 catalysts. X-ray absorption spectroscopies and experimental studies uncovered that oxygen vacancies generated by heteroatom N doping play a key role for promoting intramolecular oxidative dehydrogenation of alcohol and 2-aminophenol derivatives to directly yield desired products. N-MnO2 catalyst rapidly oxidative dehydrogenated the reactants into corresponding benzoxazoles for 10 examples with >87.6% yields.
研究领域:
材料科学
·
催化化学
·
有机合成
✓ 已验证
DOI
高影响因子
MACROMOLECULES
·
2023
·
IF 5.5
Jirong Wang,Chi Zhang,Yong Zhang,Gong Chen,Rinaldo Poli,Xiaolin Xie,Zhigang Xue
Assembling polymer electrolytes (PEs) with lithium metal anodes is a promising strategy to address safety and specific capacity concerns. Molecular design on conductive polymer matrices avoids inherent high crystallinity, poor ion transport, and combustion drawbacks by adjusting the chain structure and functional groups. However, conventional structural modulation methods are difficult to conduct via in situ polymerization and cell assembly, thus hampering the further performance enhancement of PEs in lithium batteries. Herein, we report a simple aza-Michael addition method induced by lithium salts for designing and fabricating high-performance PEs. This method fulfills the in situ structure modulation of polyether-based PEs without any introduction of non-electrolytic components. The obtained polyether electrolytes exhibit a more amorphous cross-linked structure, leading to a favorable medium for ion migration and excellent flexibility. In addition, the introduction of C–N bonds imparts excellent non-flammability to the material as well as the ability to interact with sulfolane. Hence, the in situ-constructed gel polymer electrolyte (GPE) is characterized by a high ionic conductivity (1.76 × 10–4 S cm–1 at 30 °C) and excellent interface stability with the electrodes. The assembled Li/LiFePO4 (LFP) battery based on this newly designed GPE exhibits a high initial specific discharge capacity and a good rate performance (112.7 mAh g–1 at 5 C). Long-term stability was also demonstrated, with a capacity retention of 86.8% after 500 cycles at 0.5 C.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Yue Sun,Yingpeng Gu,Jinpeng Yang
N-heterocyclic compounds (NHCs) in industrial wastewater, such as pyridine, have potential toxicity to organisms and are difficult to biodegrade, causing great harm to the environment and human health. In this work, four sulfonic acid-functionalized resins (30-R, 40-R, 60-R and 70-R) with different sulfonation degree were prepared on the basis of the conventional hypercrosslinked resin by controlling the reaction temperature with concentrated sulfuric acid. The batch experiments showed that the adsorption capacities of pyridine on the sulfonic resins are pH-dependent, and the optimum pH increases with the increase of sulfonation degree. The adsorption of pyridine on the resin was monolayer, and the maximum adsorption capacity fitted by Langmuir model was positively correlated with sulfonation degree. The fitting results of Weber-Morris model showed that high sulfonation degree meant high intraparticle diffusion rate. The driving forces of adsorption included electrostatic attraction, π-π conjugation and hydrophobic interaction. Although the electrostatic attraction, which played the most important role, significantly improved the adsorption capacity of the sulfonic resin, it weakened the effect of the other two. This phenomenon was caused by the introduction of sulfonic groups significantly promoted the adsorption performance of the resin for single-ring NHCs, but that for fused-ring NHCs with π-electron-rich regions and strong hydrophobicity was unremarkable, or even decreased. Under the synergism of the three driving forces, sulfonic acid-functionalized hypercrosslinked resin exhibited superior adsorption performance for NHCs with easy protonation, high π-electron cloud density and strong hydrophobicity.
研究领域:
环境科学
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化学工程
✓ 已验证
DOI
高影响因子
Journal of Nanomaterials
·
2019
·
IF 2.233
Manlin Li,Weiqiu Huang,Bo Tang,Fujiao Song,Aihua Lv,Xiang Ling
The Cu-BTC, a widely studied metal-organic framework (MOF), has been applied in various fields such as gas adsorption, separation, storage, and catalysis. However, the Cu-BTC collapses due to the replacement of the organic linker by water molecules under humid conditions, which limits its practical application in industries. In consideration of the undesirable water effect on the framework stability of Cu-BTC, a stable activated carbon (AC) was incorporated into it by the in situ method to yield a composite material AC/Cu-BTC with high water stability. XRD and SEM patterns proved that the AC7%/Cu-BTC successfully retains its crystal structure after being exposed to water molecules. The adsorption amount of n-hexane vapor of the AC7%/Cu-BTC after water vapor adsorption-thermal desorption is 307% of that of the Cu-BTC. The addition of the AC changes the adsorption active sites and reduces the strong affinity of the Cu-BTC to water molecules, resulting in the AC7%/Cu-BTC having a much lower adsorption rate for water vapor than the Cu-BTC. Therefore, the AC7%/Cu-BTC can be protected from a large amount of water molecules and avoid structural collapse caused by the disconnection between the copper center and the organic linker. The composite displays a potential value for stable applications of MOF-based materials under ambient conditions.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
Petroleum Science
·
2023
·
IF 5.6
Fan Ding,Xin Jin,Tao Shen,Shan-Shan Mao,Qing Zhao,Mang-Lai Gao
Wettability is an important surface property that deserves to further explore the factors on its alteration. Series of bis -N-heterocyclic quaternary ammonium salts with different spacer length and N-heterocyclic headgroups (morpholinium (BMMB, BMMD and BMMH), piperidinium (BPMH) and piperazinium (BMPMH)) have been synthesized and employed for altering the wettability of vermiculite and its derivates (Vts) treated by Li + -saturated heating method. The results of X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TG-DTG), scanning electron microscopy (SEM) and N 2 adsorption/desorption isotherms indicate that all of the bis -N-heterocyclic quaternary ammonium salts have been successfully inserted into the vermiculite layers, leading to the organic monolayer. The results of capillary rise tests combined with Lipophilic to Hydrophilic Ratio ( LHR ) values unveil the wettability alteration of the organo-Vts. As the layer charge decreases, the hydrophilicity of the organo-Vts gradually increases, which is probably caused by the decline in binding sites. As the result of the change in spacer length of modifier, the wetting properties of morpholinium-based organo-Vts change in order of BMMD-Vts > BMMH-Vts > BMMB-Vts, and difference in N-heterocyclic headgroups leads to the sequence of wettability: BMPMH-Vts > BPMH-Vts > BMMH-Vts. Layer charge of Vt, spacer length and the type of the N-heterocyclic headgroup of modifier have the synergistic effect on the regulation of the wettability.
研究领域:
材料科学
·
表面化学
✓ 已验证
DOI
高影响因子
PROTEIN EXPRESSION AND PURIFICATION
·
2022
·
IF 2.025
Zhiting Lao,Shuanqi Li,Jinhui Liang,Jingyi Su,Xin Gong,Xiping Cui,Suqing Zhao
Glypican-3 (GPC3) has a promise to be the diagnostic biomarker as well as therapeutic target for hepatocellular carcinoma (HCC). Nanobody have the great potential in clinical diagnosis and treatment for their characteristics of small size, high solubility, stability, manipulability, binding advantages, and ease of production. In this study, the recombinant glypican-3-N terminal (GPC3-N) protein was expressed as inclusion body in E. coli BL21(DE3)pLysS cells and then purified, which is then used as the immunogen to construct nanobody phage library. The positive clone (named MF15) was obtained by four rounds of bio-panning, and then transformed into the E. coil TOP10F’ cells to express nanobody protein, with the molecular weight of 19 kDa. Both Western blot and immunofluorescence analysis revealed that bacterially expressed GPC3-N protein is biologically active, and MF15 could specifically recognized native GPC3 expressed in HepG2 cells. The results in this study would provide the technical support for the development of diagnostic kits and antibody drugs targeting GPC3.
研究领域:
分子生物学
·
癌症研究
·
生物技术
✓ 已验证
DOI
PubMed
高影响因子
FUEL
·
2023
·
IF 7.4
Yu Feng,Huihang Zhang,Deming Zhang,Fuqiang Chen,Xinhai Xu,Jiang Qin,Yi Jiao
The cracking of on-board hydrocarbon fuels is a strong endothermic reaction and can provide an additional chemical heat sink in the cooling process of the hypersonic vehicle. However, the cooling capacity of current hydrocarbon fuels can hardly meet the cooling requirements of the hypersonic vehicle at higher flight speeds. Blending ethanol is an effective method to improve the chemical heat sink of hydrocarbon fuels, but the mechanism of ethanol on chemical heat sink is unclear. In this study, n-decane was selected as a model compound of hydrocarbon fuels to investigate the physical and chemical effect of ethanol on the chemical heat sink of n-decane cracking by analyzing the chemical reactions involved through experimental study and chemical dynamic simulation. The results indicate that there is an optimum ethanol blend ratio to achieve the maximum chemical heat sink. The carbon monoxide methanation reaction which is an exothermic reaction can deteriorate endothermic process at 300–375 °C. With ethanol blending ratio above 20 wt%, ethanol vaporization deteriorates chemical heat sink by reducing the residence time in the temperature range of 225–250 °C. Pressure can suppress the reduction of residence time caused by ethanol evaporation and also suppress the positive reaction of ethanol cracking. The kinetic model of ethanol and n-decane mixture cracking was established. The calculated results verify that ethanol cracking ( C 2 H 5 OH =CO+ C H 4 + H 2 ) and methane cracking ( C H 4 =C+ 2H 2 ) are dominant reactions in ethanol-assisted n-decane thermal cracking below 475 °C.
研究领域:
能源科学
·
化学工程
·
航空航天工程
✓ 已验证
DOI
高影响因子
ChemCatChem
·
2025
·Vol. 17
·期 6
·e202401780
·
IF 3.9
Jingru Li,Siyuan Hu,Longmei Shang,Guowu Zhan
Graphical This study investigates N -doped Co 3 O 4 /Pt catalysts synthesized using a Pt-decorated ZIF-67 sacrificial template, followed by a water-soaking treatment to enhance surface hydroxyl (-OH) group content. The interfacial N -stabilized Co 3+ -OH-Pt active sites in N -Co 3 O 4 /Pt improved synergy between cobalt and platinum, enhancing agglomeration resistance and enhancing catalytic performance. CO 2 hydrogenation is a promising method for converting CO 2 into valuable products. Cobalt-based catalysts are favored for their low cost and high activity, but they face challenges from sintering-induced deactivation. This study investigates N -doped Co 3 O 4 /Pt catalysts synthesized using a Pt-decorated ZIF-67 sacrificial template, followed by a water-soaking treatment to enhance surface hydroxyl (─OH) group content. The as-designed N -Co 3 O 4 /Pt catalyst achieved a CO 2 conversion of 64% and CH 4 selectivity of 98% at 340 °C under ambient pressure. It was demonstrated that the interfacial N -stabilized Co 3+ -OH-Pt active sites in N -Co 3 O 4 /Pt improved synergy between cobalt and platinum, enhancing agglomeration resistance and enhancing catalytic performance. In situ diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) demonstrated that CO 2 is converted to methane mainly through a formic acid pathway, with no CO detected. This work underscores the critical role of surface hydroxyl groups in promoting CO 2 adsorption and activation, guiding the CO 2 methanation reaction toward efficient methane production.
研究领域:
催化化学
·
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 71
·57482-57489
·
IF 3.84
Qianchun Zhang,Feifei Meng,Lin Zha,Xingyi Wang,Guoyi Zhang
In this paper, we developed a cataluminescence-based sensor using SrCO3/graphene for sensitive and selective detection of n-propanol. The composite was characterized by X-ray diffraction, transmission electron microscopy, Fourier transform infrared spectroscopy, and gas adsorption. The sensor was coupled with a miniature vaporizing device to detect n-propanol in liquid samples. The experimental results revealed that the SrCO3/graphene sensor exhibited a sensitivity for n-propanol 5.8 times higher than that of pure SrCO3, indicating that the sensitivity of the SrCO3/graphene sensor was increased by adding graphene to SrCO3. The linear range of the sensor was 0.2 to 32 mg L−1 (r = 0.9987) with a limit of detection of 0.08 mg L−1. The sensor showed a rapid response of 2 s and a recovery time of 20 s, respectively. The sensor was used to analyze samples spiked with known concentrations of n-propanol. The concentrations of n-propanol in all samples were well quantified with satisfactory recoveries, indicating that the SrCO3/graphene sensor is a promising candidate for fast, sensitive, selective detection of n-propanol. We also discuss the possible mechanism based on the reaction products.
研究领域:
分析化学
·
材料科学
✓ 已验证
DOI
高影响因子
Frontiers in Energy
·
2023
·Vol. 18
·期 1
·42-53
·
IF 2.9
Fang Can,Tang Xiangmei,Wang Jiaoyan,Yi Qingfeng
Highly efficient and stable iron electrodes are of great significant to the development of iron-air battery (IAB). In this paper, iron nanoparticle-encapsulated C-N composite (NanoFe@CN) was synthesized by pyrolysis using polyaniline as the C-N source. Electrochemical performance of the NanoFe@CN in different electrolytes (alkaline, neutral, and quasi-neutral) was investigated via cyclic voltammetry (CV). The IAB was assembled with NanoFe@CN as the anode and IrO 2 + Pt/C as the cathode. The effects of different discharging/charging current densities and electrolytes on the battery performance were also studied. Neutral K 2 SO 4 electrolyte can effectively suppress the passivation of iron electrode, and the battery showed a good cycling stability during 180 charging/discharging cycles. Compared to the pure nano-iron (NanoFe) battery, the NanoFe@CN battery has a more stable cycling stability either in KOH or NH 4 Cl + KCl electrolyte.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）