ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2026
·
IF 3.8
Xia Yong,Wang Qi,Wang Xu,Shan Liancong,Zhang Bo,Li Sheng,Guo Chang
The accurate and rapid detection of fluoroquinolone antibiotics (FQs) is crucial, yet their structural homology often leads to cross-reactivity that compromise accuracy. Herein, we designed a poly(3,4-ethylenedioxythiophene) doped with a poly(styrenesulfonate) (PEDOT:PSS)-based dual-channel organic electrochemical transistor (OECT) array on a flexible, low-cost polyimide substrate. By leveraging the synergistic catalysis of single-walled carbon nanotubes (SWCNTs) and gold nanoparticles (AuNPs), effective discrimination of three FQs was achieved using gate electrodes modified with only two Nafion/SWCNTs/AuNPs composites, differing solely in AuNP mass fraction—this significantly simplifies fabrication for an electronic tongue system (ETS). Aided by principal component analysis (PCA), the system discriminates and quantifies ofloxacin (OFL), levofloxacin (LEV), and ciprofloxacin (CIP) across a wide concentration range of 0.4–1000 μM, with limits of detection (LODs) of 0.32–0.40 μM, while exhibiting excellent selectivity, anti-interference, consistency, stability, and rapid response. The comprehensive performance of this platform establishes a practical foundation for portable FQ sensing in environmental and clinical applications. Graphical abstract
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2026
·
IF 7.7
Songjia Luo,Xianzhi Dou,Lu Wang,Lei Zheng
Chloramphenicol (CAP) residues in milk pose severe health risks, yet current detection methods (e.g., chromatography-mass spectrometry) suffer from complexity and high costs. In this work, we address this gap by developing an ultrasensitive aptamer-gated graphene Field-effect biosensor. A self-assembled Aptamer-functionalized solution-gated graphene transistor (Apt-SGGT) was engineered via systematic optimization of aptamer surface density to overcome spatial-confinement limitations and enhance conformational switching efficiency. We applied the Apt-SGGT biosensor to the analytical determination of CAP in actual skim milk samples, achieving a detection limit as low as 21.5 pM with a spiked recovery rate of 97.65 % ± 5.72 %. This study not only presents a promising platform for the rapid, on-site detection of antibiotic residues in complex food matrices but also provides a generalizable interfacial engineering strategy to enhance the performance of aptamer-based field-effect biosensors.
✓ 已验证
产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2026
·
IF 4.6
Yulong Han,Huanhuan Lu,Haili Liu,Hengye Chen,Wei Lan,Xinming Lv,Wanjun Long,Haiyan Fu
In this work, a ratiometric fluorescent sensing platform based on the antenna effect of Tb-doped metal – organic framework (Tb-MOF) was constructed for sensitive and visual detection of enoxacin (Eno). The coordination of Tb 3+ with the β-diketone structure of the Eno molecule activates yellowish-green fluorescence emission through the “antenna effect”. The Tb-MOF fluorescent probe exhibits excellent response-sensitivity and selectivity for Eno with a low detection limit (LOD) of 0.09 μM, showing a good linear response in the concentration range of 0–20 μM. Under excitation with 365 nm ultraviolet light, the fluorescence color of the sensor system gradually changes from blue to yellow-green as the Eno concentration increases. Further, Tb-MOF ratiometric fluorescent sensor combined with cloud-based machine learning algorithm-assisted WeChat Mini Program realized the intelligent quantification of Eno in complex matrices such as honey, milk, and beef was achieved, which overcomes the reliance of traditional methods on large-scale instruments and provides a portable and efficient solution for on-site monitoring of food safety.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 2
·81
·
IF 5.3
Zhang Haili,Peng Man,Lu Anjiang,Peng Xishun,Wang Cunwei,Zu Caizhen,Bai Zhongchen
A surface-enhanced Raman scattering (SERS) sensor of Au/Ag nanoparticles (NPs) grown on ZnO/polypyrrole@Poly(3,4-ethylene dioxythiophene)-poly(styrene sulfonate) (PPy@PEDOT:PSS) film for detecting norfloxacin (NFX) residues in milk is presented. The ZnO/PPy@PEDOT:PSS film was prepared by the electrochemical deposition method. Subsequently, Ag NPs and Au NPs were deposited on the surface of ZnO/PPy@PEDOT:PSS film to form a Au/Ag/ZnO/PPy@PEDOT:PSS film by an electrochemical deposition process and the magnetron sputtering process, respectively. Owing to the charge transfer between the SERS substrate and the NFX molecules, this SERS sensor could effectively identify low-concentration NFX molecules with a limit of detection (LOD) of 0.84 nM. Moreover, it could also recognize NFX residues in milk with recoveries of 91.2% to 108.4%. The SERS sensor of Au/Ag/ZnO/PPy@PEDOT:PSS film had a high sensitivity, excellent long-term stability, and significant potential in food safety monitoring applications. Graphical abstract
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
·
2026
·Vol. 132
·期 3
·226
·
IF 3
Hong Khanh Trung,Dang Huu Phuc,Le Hanh Ngoc Thi,Dieu Nguyen,Duyen Ky,Nguyen Quoc Thang,Nguyen Van Cuong
This study introduces a rapid synthesis method for nitrogen-doped carbon quantum dots (N-CQDs) using microwave irradiation, with citric acid and urea serving as the carbon and nitrogen sources, respectively. The material was characterized by Fourier transform infrared (FTIR) spectroscopy, transmission electron microscopy (TEM), ultraviolet-visible (UV-Vis) spectroscopy, and fluorescence spectroscopy, revealing a uniform structure, nanoscale size (4–10 nm), and excellent optical properties. N-CQDs were used as fluorescent sensors to detect Fe³⁺ ions and oxytetracycline (OTC) with high sensitivity and selectivity. The results demonstrated limits of detection (LOD) of 1.685 µM and 0.638 µM for Fe³⁺ and OTC, respectively, within linear ranges of 1–32 µM and 0.2–100 µM, respectively. The fluorescence quenching mechanism for Fe³⁺ was attributed to static quenching, whereas OTC enhanced the fluorescence via hydrogen bonding and π–π interactions. The analytical performance of the N-CQDs surpassed that of many previously reported methods, highlighting their potential for environmental sensing and antibiotic residue monitoring.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 3
·168
·
IF 5.4
Ma Ya,Zheng Yuqing,Wang Jiahao,Bai Liwei,Liu Jizhong,Bai Weidong,Zhao Xiaojuan
Cu-metal organic framework (MOF) derived porous carbon (Cu/Cu 2 O@C 700 ) derived from Cu-based MOF was prepared by one-step pyrolysis, and then used together with nitrogen-doped longan shell carbon (NCs) to establish a new electrochemical sensor for the rapid detection of enrofloxacin (ENR) by differential pulse voltammetry. The materials and the preparation process of electrochemical sensor were characterized. Results have shown that Cu/Cu 2 O@C 700 exhibited abundant porous structures, high surface area, and numerous active sites, which significantly improved response sensitivity. NCs is a porous carbon material which possess high specific surface area and make the diffusion and transport of electrolyte ions easier. Under optimal conditions, the peak current of ENR exhibits favorable linear relationships with the concentration within a range 0.1–1000 ng mL − 1 , and the detection limit is 7.73 × 10 − 3 ng mL −1 (S/ N = 3). The sensor has good selectivity, stability and repeatability, and good recovery (93.90 ~ 104.0%, RSD<4%) for the detection of ENR in fresh fish and shrimp. Compared with LC-MS/MS, it also shows competitive accuracy, which is of great significance in ensuring the safety of aquatic products. Graphical abstract
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Water Process Engineering
·
2026
·
IF 6.6
Yi Ming Jun
β-CD to Fe-Al oxyhydroxide e − transfer induces positive ESP shift, forming e − -deficient cavity. • Activated β-CD cavity enhances TC affinity, supported by experiments and simplified DFT. • Composite achieves 152 mg/g capacity and good reusability and selectivity. • Cooperative enrichment-stabilization: β-CD recognition & Fe coordination. The development of high-performance adsorbents is often constrained by an inherent trade-off between rapid sequestration kinetics and strong binding capacity. To address this bottleneck, we rationally design a β-cyclodextrin-modified mixed-valent iron (Fe 2+ /Fe 3+ ) ‑aluminum hydroxide hybrid composite (CD-FeAl-HC) for efficient tetracycline (TC) removal. A unique cooperative enrichment-stabilization mechanism is realized in this structured composite: interfacial activated β-CD acts as a molecular recognition unit that rapidly pre-concentrates TC from bulk solution, while the adjacent mixed-valent Fe 2+ /Fe 3+ sites provide strong coordination binding for stable immobilization. DFT calculations further reveal that interfacial electron transfer from β-CD to FeAl-HC induces a distinct positive shift in the electrostatic potential of the β-CD cavity, converting it from an inert pocket into an electron-deficient molecular trap. Benefiting from this synergistic effect, CD-FeAl-HC delivers a competitive maximum adsorption capacity (151.99 mg/g), remarkably fast adsorption kinetics, and excellent anti-interference performance against coexisting ions and natural organic matter. Notably, the composite achieves over 90% removal efficiency for both TC and ofloxacin in mixed solution, while maintaining >90% TC removal in real water matrices (reservoir and landscape water). Furthermore, it retains more than 90% of removal efficiency after 10 consecutive adsorption-desorption cycles, demonstrating outstanding reusability. This work establishes a generalizable design strategy that integrates molecular enrichment and surface stabilization within a single hybrid material, providing a promising framework for the rational construction of high-performance adsorbents toward emerging organic pollutant remediation. Download: Download high-res image (160KB) Download: Download full-size image
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL LETTERS
·
2025
·
IF 1.8
Xuemei Wang,Xue Zhang,Yunsheng Shang,Guohai Yang,Xin Zhang,Lu-Lu Qu,Yingqiu Gu
Surface-enhanced Raman spectroscopy (SERS) is a powerful tool for the rapid, real-time monitoring of trace aquatic pollutants. However, a major challenge persists in the development of SERS substrates capable of simultaneously determining and degrading pollutants. Herein, a highly sensitive Au/TiO2/Au sandwich-structured substrate was fabricated that exhibited excellent SERS performance with an enhancement factor (EF) of 1.05 × 107. Limits of detection (LODs) as low as 1.42 × 10−7 M for ofloxacin (OFL) and 1.26 × 10−9 M for trimethoprim (TMP) were achieved. Notably, the substrate retained stable SERS activity even after five consecutive detect-degrade cycles. By integrating plasmonic enhancement (for SERS detection) with photocatalytic degradation (for pollutant removal), this dual-functional platform demonstrated high reproducibility, with a relative standard deviation (RSD) below 6%, and long-term stability, retaining 60% of its initial SERS intensity after 60 days of storage. The strategy reported herein provides a practical approach for the simultaneous determination and degradation of antibiotics in aqueous matrices.
✓ 已验证
产品关联
DOI
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2023
·
IF 22.1
Ding Liu,Zhenkun Su,Bo Han,Kaisheng Xia,Chenggang Zhou,Qiang Gao
Cobalt–aluminum oxide clusters-embedded γ-Al 2 O 3 nanosheets (CAO@AO) were facilely fabricated and developed for peroxymonosulfate (PMS) activation. Interestingly, the Al–OH-rich amphiphilic surface of CAO@AO endowed the catalyst with unique interfacial pH-buffering property, which stabilized the reaction media at nearly neural level and thus prevented the cobalt sites from leaching. Moreover, the presence of Al–OH groups around the Co−Al oxide clusters facilitated the activation of PMS and the redox cycle of Co 2+ /Co 3+ , which resulted in a boosted catalytic activity. Consequently, the CAO@AO exhibited zero leaching of cobalt and high efficacy for PMS activation, enabling complete and ultrafast removal of metronidazole with a significantly higher turnover frequency (TOF, 1.83 min −1 ) than that of Co 3 O 4 (0.004 min −1 ). It was also demonstrated that introducing suitable foreign metal into CAO@AO could further enhance the catalytic activity (e.g., TOF of Mn(40%)-CAO@AO: 5.80 min −1 ). Furthermore, Mn(40%)-CAO@AO-decorated granular support was synthesized that dominated a continuous-flow degradation in column reaction system.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Peng Xu,Xiang Li,Rui Wei,Chunyan Yang,Tianyao Shen,Peng Wang,Guangshan Zhang
The adaptability and stability of catalysts guarantee efficient catalytic performance. Hence, we fabricated FeCo 2 O 4 /diatomite for efficient peroxymonosulfate (PMS) activation. Distinct from stacked FeCo 2 O 4 , FeCo 2 O 4 /diatomite possessed a 1.2-fold larger specific surface area (94.84 m 2 g −1 ), achieving 100% ATZ removal within 10 min at 0.2 g L −1 PMS and 0.1 g L −1 FeCo 2 O 4 /diatomite. The system could adapt to a broad pH range (3–11) and complex water matrices, efficiently removing multiple contaminants. High removal performance (>92%) and mineralization (>57%) were maintained after six cycles with minimal leached Co (0.10 mg L −1 ). The conversion between ≡Fe(III)/≡Fe(II) and ≡Co(III)/≡Co(II) could trigger PMS persistently, producing abundant active species, in which SO 4 •− was dominant. Then, intermediates and degradation pathways were proposed based on DFT calculations and ESI-QTOF-MS/MS data. Toxicity analysis showed that most intermediates were more eco-friendly than ATZ. This study developed FeCo 2 O 4 /diatomite with superior catalytic performance, high adaptability, and stability for eliminating refractory organic pollutants.
✓ 已验证
产品关联
DOI
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2023
·
IF 9.8
Roujia Du,Qianxin Zhang,Frank Leresche,Mengmeng Zhong,Ping Chen,Jun Huang,Shubo Deng,Fernando L. Rosario-Ortiz,Gang Yu
To determine and predict the reaction rate between 3 DOM* and PPCPs in various water bodies, this study defines a reaction rate coefficient ( α 3 DOM ∗ ) to describe the reaction between 3 DOM* and PPCPs. As the values also included the inhibition effect of DOM's antioxidant moieties, the calculation of α 3 DOM ∗ is inconsistent with that of a bimolecular rate constant via the steady-state kinetic method. The α 3 DOM ∗ values of 12 selected PPCPs were determined in two DOM solutions and ten DOM-containing water samples collected from typical surface water bodies in Beijing. The Pearson coefficients between nine predictors including the absorbance ratio (E2/E3), specific absorption coefficient at 254 nm (SUVA 254 ), fluorescence index (FI), biological index (BIX), humification index (HIX), pH, total organic carbon (TOC), total fluorescence intensity (TFI) and TOC normalized TFI (TFI/TOC) and α 3 DOM ∗ were examined. Correlation patterns for sulfonamides, β-blockers and diclofenac supported the electron transfer pathway, and was distinctly different from those appeared for FQs where quenching effect played a main part. TFI and TFI/TOC were recognized as the most useful surrogates in empirically predicting α 3 DOM ∗ . For PPCPs that went through the electron transfer pathway, α 3 DOM ∗ could be well fit to the Rehm-Weller model assuming a proportional relationship between TFI and △G et . For FQs, α 3 DOM ∗ was found to linearly correlated with TFI/TOC. The α 3 DOM ∗ values determined in this study enrich the database of PPCPs photolysis parameters, and the correlation analysis provides reference for forecasting PPCPs fate in the aquatic environment.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Junyang Pan,Dan Hua,Yiping Hong,Xi Cheng,Fangsong Guo,Kok Bing Tan,Ziqi Zhong,Guowu Zhan
Photocatalytic membranes with concurrent catalytic oxidation and separating functions possess promising potentials for the degradation of organic pollutants in wastewater treatment. Herein, we designed a hybrid photocatalytic membrane ( viz. , g-C 3 N 4 /GO/MCE) by vacuum-filtration-assisted assembling method, consisting of graphitic carbon nitride (g-C 3 N 4 ) nanosheets as a top layer, graphene oxide (GO) nanosheets as an interlayer, and commercial mixed cellulose ester (MCE) as a substrate layer. The microstructures, chemical compositions, and physicochemical properties of the designed g-C 3 N 4 /GO/MCE membranes were systematically characterized by a series of characterization techniques. Particularly, photocatalysis-filtration reactor cells were designed for the evaluation of the simultaneous separation and photocatalytic degradation performance in a single unit using both organic dyes and antibiotics as modeling pollutants in wastewater. Four parameters were adopted to represent the integrated photocatalysis-filtration performance of our designed photocatalytic membranes, including permeance ( P ), rejection ( R’ , filtration alone), removal ( R , combined photocatalysis-filtration under light-irradiation), and degradation rate ( D ). The hybrid membranes showed superior permeance and solute removal under visible-light irradiation (300 W, λ > 420 nm), in which the permeance was 20% higher than that of no-irradiation conditions. In addition, 10 consecutive cycling tests and light-on/off cycles of the as-prepared g-C 3 N 4 /GO/MCE membrane toward RhB showed quite stable permeance in the range of 268.9 to 352.9 L h −1 m −2 bar −1 , and the removal was maintained in the range of 88.4% to 95.4%, indicating excellent long-term stability. Remarkably, it also exhibited good removal performance of antibiotics ( e.g. , ofloxacin, norfloxacin, sulfamethoxazole, erythromycin, and roxithromycin). Accordingly, the designed hybrid g-C 3 N 4 /GO/MCE photocatalytic membranes with excellent photocatalytic activity and photocatalysis-filtration performance are promising for wastewater treatment and water purification applications.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）