JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 42
·19957-19971
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IF 4.682
Zhu Beibei,Song Pingan,Li Jingguo,Cao Shaokui,Shi Jun
Photodynamic therapy as an antibiotic-free method could effectively solve the bacterial infection problem and avoid the emergence of multidrug-resistant bacteria. In this paper, Ti 3 C 2 @gold nanorods (GNRs)/PDA nanoparticles with synergistic photodynamic antibacterial properties were obtained by coating PDA on the surface of in situ growth Ti 3 C 2 @GNRs. GNRs growing on the surface of Ti 3 C 2 MXene nanosheets effectively prevented the aggregation of Ti 3 C 2 nanosheets, which ensured the distinct photodynamic antibacterial performance of Ti 3 C 2 . In addition, the introduction of SH-PEG-CH 3 to Ti 3 C 2 @GNRs nanosheets endowed Ti 3 C 2 @GNRs/PDA nanoparticles with good biocompatibility. Furthermore, Ti 3 C 2 @GNRs/PDA nanoparticles possessed synergistically enhanced photodynamic properties, caused by the remarkable photodynamic properties of Ti 3 C 2 MXene and PDA. In addition, with the increase in PDA content, Ti 3 C 2 @GNRs/PDA nanoparticles could produce more 1 O 2 under 660 nm laser irradiation and the minimum inhibitory concentrations of Ti 3 C 2 @GNRs/PDA 50 nanoparticles against E. coli and S. aureus decreased to about 0.07 mg/mL. Thus, this work utilizes the 1 O 2 -generating performance of Ti 3 C 2 MXene and PDA to fabricate Ti 3 C 2 @GNRs/PDA nanoparticles with synergistically enhanced photodynamic antibacterial activities, which is expected to be applied in antibiotic-free antibacterial field. Graphical abstract
研究领域:
材料科学
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生物医学工程
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微生物学
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产品关联
DOI
高影响因子
EUROPEAN POLYMER JOURNAL
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2024
·
IF 5.8
Jiaofeng Ye,Shuanglong Chen,Libang Feng,Jianbin Zhang,Yanhua Liu,Danbin Zhu
Self-healing polyurethane used in architectural engineering often suffers from contradictory mechanical and self-healing properties, limited repair options and low repair efficiency. In this research, a series of self-healing polyurethane materials were manufactured by introducing Fe 3 O 4 , polydopamine (PDA) and Fe 3 O 4 @PDA nanoparticles into polyurethanes based on thermo-reversible Diels-Alder reaction. These nanoparticles endowed self-healing polyurethane with multiple responses to thermal, NIR and microwave. Consequently, the evident cracks were renovated quickly and repeatedly upon these excitations. Therefore, the nanoparticles not only improved the healing efficiency markedly, but also endowed polyurethane with multiple responsive self-healing ability. Interestingly, due to the synergistic interaction between photothermal effect, microwave effect, and rigidity of Fe 3 O 4 as well as photothermal effect and compatibility with organic matrix of PDA, Fe 3 O 4 @PDA-modified polyurethane was empowered with the most exceptional mechanical and self-healing properties. Results revealed that Fe 3 O 4 @PDA nanoparticles-modified polyurethane exhibited high mechanical properties such as strength, toughness and hardness as well as excellent multiple stimulus response self-healing performance. More importantly, results revealed that the recycled self-healing and multiple stimulus response ability of nanoparticles-modified self-healing polyurethane was implemented grounded on four synergistic effects of photothermal effect of nanoparticles, thermo-reversible Diels-Alder reaction, thermal movement of molecular chains and nanoparticles, and the dissociation and regeneration of hydrogen bonds. This research provided an ideal approach for numerous options for cracks repairing used in construction industry when exposed in harsh environments.
研究领域:
材料科学
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纳米技术
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高分子化学
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工程材料
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产品关联
DOI
高影响因子
CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2023
·
IF 3.8
Pan Wang,Mengdei Zhou,Zhuangxin Wei,Lu Liu,Tao Cheng,Xiaohua Tian,Jianming Pan
Molecularly imprinted polymers (MIPs) have great potential as adsorbents for selective adsorption and separation of nucleoside compounds, but effectively enhancing the affinity of recognition sites by adjusting the forces between template molecules and functional monomers remains an important challenge. In this work, a surface imprinting strategy was used to construct bowl-shaped molecularly imprinted composite sorbents (BHPN@MIPs) based on polydopamine (PDA) particles and have achieved selective separation and purification of 2′-deoxyadenosine (dA). Where by the base complementary pairing interaction of the combined template molecule dA and the pyrimidine functional monomer can enhance the pre-assembly force, and the hydrophilic bowl-shaped PDA can provide a larger storage space contact efficiency of dA in the test solution, causing the site utilization much higher and improving the kinetic adsorption performance. The equilibrium adsorption time and maximum adsorption capacity of 60 min and 328.45 μmol·g −1 were observed by static adsorption experiments, and the selectivity experimental results showed an imprinting factor IF of 1.30. After four adsorption–desorption cycles, the initial adsorption equilibrium adsorption capacity of BHPN@MIPs still retained 91.14%. By evaluating the selective adsorption of dA in spiked human serum solutions, BHPN@MIPs can be used to selectively enrich and analyze target dA in complex biological samples.
研究领域:
材料科学
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分析化学
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生物技术
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药学
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产品关联
DOI
高影响因子
Green Energy & Environment
·
2020
·
IF 6.395
Qingmiao Wang,Yi Qin,Feifei Jia,Shaoxian Song,Yanmei Li
Volumetric solar evaporations by using light-absorbing nanoparticles suspended in liquids (nanofluids) as solar absorbers have been widely regarded as one of the promising solutions for clean water production because of its high efficiency and low capital cost compared to traditional solar distillation systems. Nevertheless, previous solar evaporation systems usually required highly concentrated solar irradiation and high capital cost, limiting the practical application on a large scale. Herein, for the first time in this work, polydopamine (PDA)-capped nano Fe 3 O 4 (Fe 3 O 4 @PDA) nanofluids were used as solar absorbers in a volumetric system for solar evaporation. The introduction of organic PDA to nano Fe 3 O 4 highly contributed to the high light-absorbing capacity of over 85% in wide ranges of 200–2400 nm because of the existence of numerous carbon bonds and pi (π) bonds in PDA. As a result, high evaporation efficiency of 69.93% under low irradiation of 1.0 kW m −2 was achieved. Compared to other nanofluids, Fe 3 O 4 @PDA nanofluids also provided an advantage in high unit evaporation rates. Moreover, Fe 3 O 4 @PDA nanofluids showed excellent reusability and recyclability owing to the preassembled nano Fe 3 O 4 , which significantly reduced the material consumptions. These results demonstrated that the Fe 3 O 4 @PDA nanofluids held great promising application in highly efficient solar evaporation.
研究领域:
材料科学
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环境科学
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能源科学
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2026
·
IF 8.7
Xuejin Zhang,Chao Hu,Yuanyuan Xia,Jingshun Zhuang,Minmin Chang,Lingqi Huang,Zhixin Jia,Qingzhi Ma,Shangru Zhai,Chang Geun Yoo
Bacterial cellulose (BC) aerogels provide a renewable biological macromolecular scaffold for constructing functional separation media due to their three dimensional nanofibrous network and abundant hydroxyl groups. In this study, BC derived composite aerogels were developed via a multiscale functional coordination approach, incorporating Fe 3 O 4 @PDA nanoparticles and silane derived hydrophobic domains into the cellulose framework. The BC macromolecular network preserved the porous architecture and supplied reactive sites for PDA mediated anchoring and silane condensation, while Fe 3 O 4 @PDA and FAS/MTMS enhanced interfacial adhesion, surface roughness, magnetic recoverability, and water repellency. The resulting composite aerogel exhibited excellent comprehensive performance, such as acid and alkali resistance, thermal stability, and self-cleaning ability. It retained over 80% recovery after 100 compression cycles at 50% strain and displayed outstanding hydrophobic and oleophilic behavior (water contact angle 161.9°) in oil/water separation. The adsorption capacities for oils and organic solvents were ranged from 20.73 to 48.21 g/g with over 85% capacity retention after 50 adsorption/desorption cycles and a continuous separation efficiency of 99.93%.
✓ 已验证
DOI
高影响因子
PROGRESS IN ORGANIC COATINGS
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2024
·
IF 6.5
Xinyuan Wang,Xiaohua Jia,Hongyan Ren,Jin Yang,Haojie Song
Self-cleaning coatings need to have a certain degree of breathability to avoid peeling due to interfacial stress. In this study, a multifunctional superhydrophobic breathable DDA-PDA@BNNS/silicon resin coating is successfully designed by modifying sucrose-assisted exfoliation of boron nitride nanosheets (BNNS) with dodecylamine (DDA) and polydopamine (PDA). The coating shows a contact angle as high as 153.6° and a rolling angle as low as 4.8°, which can effectively avoid the adhesion of solid and liquid contaminants and extend the freezing time of ice up to six times. Meanwhile, the porous network structure of boron nitride nanosheets hardly changes the water vapor transmission rate of the substrate material . The DDA-PDA@BNNS/silicon resin breathable superhydrophobic coating is expected to achieve practical applications in long-lasting self-cleaning and antifouling.
研究领域:
材料科学
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表面工程
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产品关联
DOI
高影响因子
FIBERS AND POLYMERS
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2024
·
IF 2.2
Zhou Xinnan,Xin Binjie,Gao Di,Newton Md. All Amin
In the purification of oily wastewater, polyvinylidene fluoride (PVDF) nanofiber membranes have attracted widespread attention for their excellent water–oil separation performance. And chitosan (CS), as a natural polymeric alkaline polysaccharide containing many functional groups interacting with heavy metal ions, such as –NH 2 and –OH, has been widely used to treat heavy metal ions in wastewater. However, a few studies have been conducted on superhydrophilic and underwater hydrophobic PVDF composite membranes for the simultaneous removal of heavy metal ions and oil from wastewater. In this paper, PVDF/PVP composite membranes were used as the substrate of separation membranes, and PVDF/PVP-modified membranes were prepared by surface coating with PDA and CS in turn. Among them, CS can be coated on the surface of PVDF/PVP composite membrane by cross-linking the amino group on the molecule with the quinone structure in the PDA molecule to form a stable CS/PDA gel layer. Compared with other modified membranes, CS/PDA-PVDF/PVP has better hydrophilicity and underwater oleophobicity. The underwater OCA of dichloromethane could reach 161°, and the OCA of other oils were above 140°. The water flux was 14,171 L m −2 h −1 . After 15 mixture and emulsion separation tests, the separation efficiency was higher than 99% and 98%, respectively. The adsorption efficiency for Cu 2+ , Pb 2+ , and Cr 3+ aqueous solutions with concentrations of 10–60 mg/L reached more than 80%. Therefore, this method has great potential in treating oily wastewater.
研究领域:
环境科学
·
材料科学
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产品关联
DOI
高影响因子
ACS Biomaterials Science & Engineering
·
2018
·
IF 4.432
Yifei Zhu,Lili Yao,Wenjian Weng,Kui Cheng
Polydopamine (PDA) is capable of adhering on nearly all kinds of surfaces and shows good biocompatibility. Moreover, its surface state could be switched between oxidation and reduction states under different electrical stimulation. In this work, the effects of PDA redox states on protein adsorption, as well as the subsequent effects on cellular responses were characterized and evaluated. It was found that the electrical treatment changed the redox states of PDA, which in turn changed the state of preadsorbed protein molecules and eventually affected the cellular responses. BSA preadsorbed PDA film was found to be beneficial for cell proliferation when PDA was changed into reduction state (RPDA), while BMP-2 preadsorbed PDA film showed promotion on cell differentiation when PDA was changed into oxidation state (OPDA). It was found that the transitions of PDA to RPDA and OPDA greatly changed the secondary structure of protein preadsorbed on it. This work provides a deeper insight on changes of protein molecules between cells and PDA surfaces with different redox states, which is important for both optimization of cell–material interactions and application of PDA as a functional coating for biomedical engineering.
研究领域:
生物材料学
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细胞生物学
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生物医学工程
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DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2022
·
IF 5.518
Wenjie Xu,Cong Yang,Wenming Su,Nongjun Zhong,Xinnian Xia
Adding functional inorganic two-dimensional nanomaterials is an effective means to improve the long-term anti-corrosion ability of polymer coatings . Here, due to the mussels’ adhesive ability to various substrates, polydopamine (PDA) was used to modify hexagonal boron nitride (h-BN) and a novel PDA-BN@CeO 2 nanohybrid was synthesized through an in situ hydrothermal approach. X-ray diffraction analysis (XRD), scanning electron microscopy (SEM), Fourier transform infrared (FT-IR) spectroscopy, and X-ray photoelectron spectroscopy (XPS) were employed to characterize the as-prepared nanomaterials. The results of salt spray test and electrochemical measurement showed that the composite coatings exhibited a notable superiority in enhancing the anti-corrosion performance, in which the |Z| 0.01 Hz was nearly three orders of magnitude higher than that of the neat epoxy coatings when soaked for 35 days. The enhancement mechanism can be attributed to the synergistic effect of BN nanosheets extending the corrosion medium diffusion pathway and CeO 2 acting as a corrosion inhibitor to block the contact of corrosion ions with the metal substrate. This study provides a new way for the development of h-BN-based anti-corrosion materials.
研究领域:
材料科学
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腐蚀与防护
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纳米技术
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产品关联
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2025
·
IF 5.6
Wenbin Nan,Hao Wang,Linxiao Li,Jiulong Du,Xiangjuan Wei,Dongmei Wang,Yan Yang,Yongxue Wang,Dan Ding,Hongli Chen
The persistence of non-healing diabetic wounds is frequently attributed to excessive inflammation and bacterial infections. Therefore, strategies that target the reduction of inflammation while simultaneously inhibiting bacterial proliferation may offer an effective approach to overcoming this clinical challenge. In this study, we have developed an innovative formulation of hyaluronic acid (HA)-based dissolving microneedles (Cu(II)-PDA/ORI MNs) that incorporate oridonin (ORI) and Cu(II)-PDA nanoparticles, specifically designed for the treatment of chronic wounds in diabetic murine models. Our findings demonstrate that the composite MNs exhibit robust mechanical properties, facilitate drug delivery to the deeper layers of the skin, and exhibit favorable cytocompatibility and hemocompatibility. The encapsulation of ORI within the MNs effectively modulates the phenotype of RAW264.7 macrophages and exhibits significant anti-inflammatory properties, thereby contributing to the reduction of excessive inflammation within the wound microenvironment. Cu(II)-PDA nanoparticles significantly mitigate the toxicity associated with Cu(II) while retaining substantial antibacterial efficacy. Furthermore, they effectively promote wound angiogenesis, thereby expediting the wound healing process. Consequently, these Cu(II)-PDA/ORI MNs emerge as promising candidates for multifunctional wound dressing applications.
研究领域:
生物医学工程
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药学
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材料科学
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产品关联
DOI
PubMed
高影响因子
Theranostics
·
2024
·Vol. 14
·期 19
·7534
·
IF 12.4
Wenfang He,Chenguang Ding,Ting Lin,Binqi Wang,Wenjing Wang,Zhichao Deng,Taian Jin,Yiwei Shang,Danna Zheng,Ting Bai,Mingzhen Zhang,Runqing Li,Juan Jin,Qiang He
Rationale : Ischemia-reperfusion-induced acute kidney injury (IR-AKI), characterized by the abrupt decline in renal function, is distinguished by the intricate interplay between oxidative stress and inflammation. In this study, a reactive oxygen species (ROS) scavenger-CF@PDA was developed to effectively target antioxidant and anti-inflammatory pathways to disrupt the oxidative stress-inflammation cycle in IR-AKI. Methods : UV-vis absorption spectra, FTIR spectra, and TEM were employed to determine the successful construction of CF@P. ABTS, TMB, and NBT analyses were performed to detect the antioxidant ability and enzyme-mimicking ability of CF@P. In vitro and in vitro , the antioxidant/anti-inflammatory effect of CF@P was detected by MTT, qPCR, fluorescence, and flow cytometry. Multi-omics revealed the mechanism of CF@P in IR-AKI therapy, and molecular docking was further used to determine the mechanism. MRI and photoacoustic imaging were employed to explore the dual-mode imaging capacity of CF@P in IR-AKI management. Results : CF@P could disrupt the oxidative stress-inflammatory cascade by scavenging ROS, reducing pro-inflammatory cytokines, and modulation of macrophage polarization. Subsequent multi-omics indicated that the renal protective effects may be attributed to the inhibition of pyruvate dehydrogenase kinase 4 (PDK4). Metabolomics demonstrated that CF@P could improve the production of antioxidant compounds and reduce nephrotoxicity. Additionally, CF@P exhibited promising capabilities in T1-MRI and photoacoustic imaging for AKI management. Conclusions : Collectively, CF@P, possessing antioxidant/anti-inflammatory properties by inhibiting PDK4, as well as imaging capabilities and superior biocompatibility, holds promise as a therapeutic strategy for IR-AKI.
研究领域:
医学
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药理学
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生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Qian Wang,Ze Zhang,Jiang Yin,Lingyi Shen,Lingli Zhu,Carl Redshaw,Qilong Zhang
Wound infections caused by pathogenic bacteria can cause delayed wound healing and even threaten the life of patients. Drug resistance and effectiveness with regard to traditional wound dressings have become urgent issues which need to be addressed. The antibacterial effect of hydrogels, as novel wound dressings, is through contact-active antibacterial was limited by the contact area and time. In this paper, MXene (a 2D carbonitride) has been employed as the substrate and via the in-situ reduction of silver nanoparticles and the polymerization of dopamine on its surface the photothermal agent MXene-Ag-PDA was obtained. This was then introduced into the hydrogel matrix via the block cationic polymer (AM-VBIMBr-AAPBA), oxidized sodium alginate (OSA) and quaternary ammonium chitosan (HACC). Multifunctional composite hydrogels (PNVAO/M-A-P) possessing photo-thermal effects and inherent antibacterial activity were obtained after crosslinking, and were employed as medical materials to promote the healing of infected wounds. The cationic groups contained in the PNVAO/M-A-P were capable of capturing and killing bacteria by electrostatic interactions, and produced local heat killing adsorption and residual bacteria in the surrounding solution under NIR irradiation, thereby shortening the antibacterial cycle and improving the sterilization efficiency. Meanwhile, the introduction of glycerin in the hydrogel improved its anti-freezing and anti-drying properties, enabling the hydrogel to function stably under extreme environments. PNVAO/M-A-P composite hydrogels based on chemical and dynamic crosslinking exhibited the desired mechanical strength, and via their self-healing ability can adapt to dynamic wounds. The hydrogel dressing showed excellent anti-freezing and anti-drying properties, high bovine serum albumin (BSA) adsorption capacity (308.17 mg·g −1 ), good biocompatibility (the cell viability exceeded 100 % after 48 h of incubation), antioxidant properties and excellent antibacterial activity (the sterilization rate can reach 99.9 %). Furthermore, the hydrogel was applied to infected wound treatment and was able to control the wound infection, reduce pro-inflammatory factor production, promote collagen deposition and neovascularization formation, and thus promote wound healing. Therefore, multifunctional composite hydrogels with synergistic antibacterial effects can be used as an novel dressing for the treatment of bacterial infected wounds.
研究领域:
生物材料学
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医学
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纳米医学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）