ANALYTICAL LETTERS
·
2023
·
IF 2
Zhe Li,Chuting Xu,Chaohui Qiu,Weimin Wang,Chuan-Fan Ding,Fuxing Xu
This article reports on the development of an atmospheric pressure filtering electrospray ionization (FESI) source – composed of a syringe, a filter, and the ESI source – for the determination of furazolidone, amoxicillin, nitrofurantoin, and nitrofural, common antibiotics. Spiked food samples were also analyzed; the analytes were placed in the filter head, and the flow rate of the extraction solution from the syringe pump was adjusted. Using a mixture of oleic acid and antibiotics, hydrophilic and hydrophobic filters were compared, demonstrating the advantage of FESI in reducing the background and noise for the mixture. The device simplifies not only the experimental procedure but also the sample pretreatment process. Additionally, the limits of detection of the antibiotics were determined to be 1 mg L−1 for furazolidone, amoxicillin, and nitrofurantoin and 2 mg L−1 for nitrofural. The linear regression coefficients (R2) of the antibiotic standard solutions were all ≥0.99. Furthermore, the spiked recovery rates of pork, chicken, and egg samples ranged from 73.3% to 107.5%, with relative standard deviations (RSDs) from 1.1% to 15.6%. This study uncovers the potential capabilities of ion trap mass spectrometry (ITMS) for the on-site detection of antibiotics and offers a new method for ensuring food safety.
研究领域:
分析化学
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质谱分析
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食品科学
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药物分析
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产品关联
DOI
高影响因子
Advanced Optical Materials
·
2023
·Vol. 11
·期 15
·2300303
·
IF 9
Dangli Gao,Zhigang Wang,Qing Pang,Qingqing Kuang,Feng Gao,Xiangyu Zhang,Sining Yun,Xiaojun Wang
UV-charged optical stimulated single-band phosphors are being used for single-level optical data storage because of their ability to easily write/read information by light. In contrast, UV–visible–NIR rechargeable optical stimulated double-band phosphor is urgently necessary for multiplexed high-throughput optical data storage. Here, the authors design and synthesize Mn 2+ ,Cr 3+ co-doped zinc gallate storage persistent phosphor that exhibits strong red-green bicolor persistent luminescence (PersL). Besides the traditional ultraviolet charging, the phosphor can be effectively and repeatedly charged by using visible and NIR light by one- or two-photon process. Interestingly, red and green PersL exhibit the opposite temperature dependence, which is extremely important for multilevel information storage. The mechanism of temperature-dependent PersL intensity based on different trap types and filling approaches for the double luminescence centers is proposed. The phosphor promises a sophisticated application in optical data storage of wavelength multiplexing.
研究领域:
材料科学
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光学工程
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产品关联
DOI
高影响因子
Surfaces and Interfaces
·
2023
·
IF 6.2
Ziwei Gao,Shurao Cai,Daomin Min,Yutao Hao,Minzun Ji,Qingzhou Wu,Shengtao Li,Wenfeng Liu
Polymer dielectric materials are crucial for storage devices in power and electronic systems, as well as electric vehicles, due to their high energy density and fast discharge rates. Polymer nanocomposites (PNCs) possess superb electrical and energy storage properties, making them highly promising as next-generation thin-film dielectrics for energy storage. The excellent performance of PNCs derive from the interfacial region introduced by nano-doping. However, the current measurement equipment and technology make it difficult to accurately obtain the mesoscopic scale distribution characteristics of the conductivity of the interfacial region, and are also impossible to clarify the formation mechanism of deep traps in the interfacial region. We employed high-throughput simulation and experiment to investigate the mesoscopic conductivity and trap distribution properties of the interfacial region in PNCs. Furthermore, we developed a three-dimensional mesoscopic conductivity distribution simulation model of PNCs containing polymer matrix, nanoparticles, and interfacial region. The interfacial region size and conductivity distribution of the PNCs were determined by comparing with the experimental results, and the mesoscopic distribution characteristics of the interfacial traps in PNCs were obtained. It is proved that the nanofillers form a condensed structure with high order and compactness by restraining the movement of molecular chains, which deepens the trap energy in the interfacial region and restricts the free volume expansion. This results in the formation of interfacial regions with low conductivity, contributing to enhancing energy storage performance.
研究领域:
材料科学
·
电气工程
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Meng Wu,Yiping Wu,Hao Song,Yanjie Zhang
Traditional anti-counterfeiting technology based on fluorescent materials is usually single-color emission and far from enough to meet the growing demand for anti-counterfeiting with high-level security. Here, dual luminescent centers with blue emission at 470 nm and green-yellow emission at 546 nm have been successfully achieved by controlling the Eu 2+ sites in the Sr x Ba 1-x Si 2 O 2 N 2 (x = 0.25–0.50) host lattices via fine-tuning of Sr contents (x). Notably, Sr 0.50 Ba 0.50 Si 2 O 2 N 2 : 0.02Eu 2+ exhibits particular optical information storage properties with intense yellow emission and can repeat the corresponding image patterns under the thermal stimulus, which can be regarded as an essential candidate in multicolor anti-counterfeiting technology. Further, the different luminescent center-trap center pairings have been found in Sr 0.33 Ba 0.67 Si 2 O 2 N 2 : 0.02Eu 2+ due to the substitution of Ba 2+ and Sr 2+ by Eu 2+ to generate blue and yellow luminescent centers and the substitution of N 3− for O 2− in the Sr and Ba lattices resulting in oxygen vacancies. Typically, Sr 0.33 Ba 0.67 Si 2 O 2 N 2 : 0.02Eu 2+ exhibits a cool white emission in photoluminescence (PL) mode and changes to yellow emission in persistent luminescence (PersL) mode. Moreover, Sr 0.33 Ba 0.67 Si 2 O 2 N 2 : 0.02Eu 2+ displays a thermochromic phenomenon (from cool white emission to blue emission) in thermally stimulated luminescence (TSL) mode, attributed to the different trap depths in Sr and Ba lattice. Hence, flexible film for optical information storage and patterns for multimodal dynamic anti-counterfeiting are fabricated using Sr 0.33 Ba 0.67 Si 2 O 2 N 2 : 0.02Eu 2+ . Finally, a dynamic optical information encryption and decryption strategy for Morse code is developed based on the different properties of Sr x Ba 1-x Si 2 O 2 N 2 : 0.02Eu 2+ (x = 0.25, 0.30, 0.33, and 0.50). The results demonstrate that Sr x Ba 1-x Si 2 O 2 N 2 : 0.02Eu 2+ (x = 0.25–0.50) phosphors can be potential candidates in optical information storage and optical anti-counterfeiting applications.
研究领域:
材料科学
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光学工程
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
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2020
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IF 8.758
Wenli Wei,Jinmei Li,Qi Wang,Dong Liu,Jingye Niu,Peng Liu
Conductive supports could improve the electrical conductivity of the electrode in lithium–sulfur (Li–S) batteries but suffer from the shuttle effect originated from the polysulfide dissolution, while the hydrophilic metal oxides could avoid the shuttle effect but with poor conductivity. Herein, a facile approach was developed to fabricate hierarchically porous tin oxide (SnO2) nanoparticle-anchored tubular polypyrrole (T-PPy) as a sulfur host, in order to integrate the advantages of conductive supports and metal oxides but overcome their shortcomings. In the unique structure, the T-PPy nanotubes acted as a conductive network to not only improve the electrical conductivity of cathodes but also accommodate the volume expansion of the sulfur cathode during cycling as well as relatively confine the polysulfide diffusion, while the SnO2 nanoparticles served as a high-efficient polysulfide trap to mitigate the shuttle effect due to the chemical bond between SnO2 and polysulfides. Moreover, the hierarchically porous structure and therefore large surface area of the proposed S/(T-PPy)@SnO2 cathode were favorable for the accommodation of sulfur and lithium sulfides. Consequently, S/(T-PPy)@SnO2 with 64.7% sulfur mass content exhibited excellent cyclic stability with a decay rate of only 0.05% per cycle along with 500 cycles at 1 C, rate capability of 383.7 mA h/g at 5 C, and Coulombic efficiency above 90%, outstanding among most of the reported PPy-based sulfur cathodes and PPy-based ternary sulfur cathodes.
研究领域:
材料科学
·
能源存储
✓ 已验证
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2026
·
IF 8.5
Dongshan Chen,Yuan Zeng,Yuanchen Liu,Haochen Cui,Yixuan Zhao,Lei Yan,Yuanwei Zang
Clear cell renal cell carcinoma (ccRCC) progression is closely associated with pro-tumorigenic neutrophil extracellular traps (NETs) within the tumor microenvironment; however, the upstream molecular mechanisms remain poorly defined. Through integrated multi-omics analysis of ccRCC cohorts, we identified ITPKB as a key downregulated gene associated with NET formation. Subsequent functional validation, including dual-luciferase reporter assays, confirmed that ITPKB is a direct target of the miR-301b-3p. Mechanistically, the loss of ITPKB prevents the ubiquitination-mediated degradation of PARP1, leading to its stabilization and accumulation. Stabilized PARP1 acts as a transcriptional co-activator for NF-κB, triggering a robust secretion of IL-8, which recruits neutrophils and induces their transformation into NETs. These NETs facilitate tumor cell migration and adhesion while conferring resistance to tyrosine kinase inhibitors (sunitinib and sorafenib) and anti-PD-1 therapy. In vivo, the treatment with DNase1 to disrupt NETs effectively reversed this therapeutic resistance. Our findings unveil the miR-301b-3p/ITPKB/PARP1/IL8/NETs axis as a novel mechanistic link between tumor-intrinsic signaling and neutrophil-driven immunosuppression, providing a solid experimental foundation for developing combination therapeutic strategies for advanced ccRCC.
✓ 已验证
DOI
PubMed
高影响因子
Journal of Materials Chemistry A
·
2024
·Vol. 12
·期 17
·10260-10268
·
IF 10.7
Yingfen Li,Xingye Chen,Runxi Wang,Nian Zhou,Fang Huang,Jun Zhao,Zhenghua Su,Shuo Chen,Guangxing Liang
In this study, Sb2S3 was introduced into the two-step selenization process to promote bottom grain growth and reduce the surface roughness of the Cu2ZnSn(S,Se)4 light-absorber layer. The introduction of Sb doping in Cu2ZnSn(S,Se)4 can passivate bulk and interface defects and a small conduction band offset (CBO) can be found, which facilitate the improvement of heterojunction carrier transport properties. Similarly, simulations illustrated that Sb doping improved device efficiency by controlling bulk and interface defects and band alignment. This optimized method facilitated the penetration of Sb, resulting in a high-quality CZTSSe absorber layer. Ultimately, the research culminated in a significant enhancement, yielding a solar cell with an impressive efficiency of 13.11%. These findings offer new possibilities for kesterite solar cells and advance the potential of CZTSSe materials in thin film photovoltaic applications.
研究领域:
材料科学
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光伏技术
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半导体物理
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薄膜太阳能电池
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无机功能材料
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固态电子学
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DOI
高影响因子
JOURNAL OF LUMINESCENCE
·
2018
·
IF 2.732
Ruoshan Lei,Xinyao Luo,Ziyuan Yuan,Huanping Wang,Feifei Huang,Degang Deng,Shiqing Xu
In this work, a new optical thermometer relying on highly temperature-dependent 1 D 2 Pr 3+ emission and temperature insensitive Y 2 Ti 2 O 7 trap emission is reported. Based on the fluorescence intensity ratio (FIR) between them, Pr 3+ : Y 2 Ti 2 O 7 with remarkably high absolute and relative sensitivities of ~ 983 × 10 −4 K −1 and 5.25% K −1 as well as good signal discriminability is realized. It also exhibits a tunable luminescent color from red to purplish blue with temperature from 289 to 573 K. The strong thermal quenching of 1 D 2 Pr 3+ emission is mainly related to the charge transfer state (CTS). Similarly, Pr 3+ : Gd 2 Ti 2 O 7 phosphor also demonstrates a favorable temperature sensing feature, indicating the temperature sensing strategy based on the combination of host trap emission and CTS interfered Pr 3+ luminescence is a promising pathway to develop high-performance optical thermometric materials.
研究领域:
光学传感
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发光材料
·
测温技术
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稀土掺杂
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固体物理
✓ 已验证
DOI
高影响因子
Redox Biology
·
2025
·
IF 11.9
Miao Zhang,Shan Gao,Nannan Tan,Yu Yan,Rongxin Zhu,Jiajing Liu,Qin Mao,Keyan Wang,Wenhao Zhang,Gang Wang,Zhuo Wang,Tieshan Wang,Xueshi Huang,Rong Zhang,Baofeng Yang
The complement system activation-induced inflammation is a critical contributor to myocardial ischemia/reperfusion (I/R) injury. However, effective therapeutic targets and pharmacological interventions remain limited. In this study, we identified 13-methylpalmatine (13-Me-PLT), a natural isoquinoline alkaloid isolated from Coptidis chinensis , as a cardio-protective agent that improved cardiac function and reduced inflammation in a rat model of myocardial I/R injury. RNA sequencing (RNA-seq) analysis revealed significant up-regulation of neutrophil extracellular trap (NET) formation-related signaling pathway and C5ar1 gene in myocardial I/R, both of which were reversed by 13-Me-PLT treatment. Bioinformatics analysis, biophysical assays, and flow cytometry confirmed that 13-Me-PLT effectively inhibited C5a receptor 1 (C5aR1) on neutrophils. However, the role of the C5a-C5aR1 axis in NET formation during myocardial I/R injury has remained unclear. In this study, using a pharmacological inhibitor of C5aR1, we demonstrated that activation of the C5a-C5aR1 axis promoted myocardial I/R injury by inducing NET formation, and that 13-Me-PLT effectively inhibited both processes in a BM213 (C5aR1 agonist)-treated rat model. In vitro , 13-Me-PLT suppressed the expression of NET-associated proteins and alleviated fibrous NET structures in neutrophils, further supporting its cardio-protective effects. In conclusion, our findings revealed that C5a-C5aR1 axis activation exacerbated myocardial I/R injury in a NET-dependent manner. 13-Me-PLT exerted cardio-protective effects by potentially inhibiting C5a-C5aR1 axis-mediated NET formation, highlighting its potential as a therapeutic candidate for myocardial I/R injury.
研究领域:
药理学
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心脏病学
·
免疫学
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分子生物学
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生物医学研究
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产品关联
DOI
PubMed
高影响因子
Advanced Optical Materials
·
2024
·
IF 8
Yixuan Xu,Zihan Cheng,Henggang Wang,Jun Jiang,Zuxu Zhou,Linger Feng,Xiaomeng Wang,Hengwei Lin,Kai Jiang
Luminescent materials with time-resolved dynamic discoloring afterglow (TDDA) hold significant potential for applications in anti-counterfeiting and data encryption. However, the afterglows coming from organic systems are usually unidentifiable due to their shorter durations (less than 10 s). Achievement of long-lasting and visually discernible TDDA remains highly desirable but challenging. In this work, the TDDA duration is successfully extended from less than 10 s to minutes by engineering the luminescent centers of carbon dots (CDs) and introducing deep trap-states in a composite of CDs and carbon nitrides (CNs) (named Y-CDs@CN). It is confirmed that the regulation of luminescent centers in CDs containing both C═N and C═O bonds is responsible for the color changes during TDDA from yellow to green. Moreover, the generation of deep trap states is found to be significant for prolonging the afterglow duration to minutes level through converting room temperature phosphorescence into long persistent luminescence, thus making the entire dynamic discoloring process being easily recognized to naked eyes. Furthermore, the afterglow of Y-CDs@CN can also be excited by blue light and even using white light of a cell phone. To harness these characteristics, potential applications of Y-CDs@CN for portable anti-counterfeiting and multidimensional information encryption are primarily investigated.
研究领域:
材料科学
·
光学
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产品关联
DOI
高影响因子
Journal of Energy Storage
·
2025
·
IF 9.8
Liang Gao,Qianqian Xiao,Chengxi Wang,Xuan Wang
Sandwich structure and encapsulation techniques are highly effective methods for reducing leakage current density ( J ) in polymer nanocomposites. However, most studies focus on electric field homogenization, and the low-field discharge energy density ( U dis ) of current polymer nanocomposites is still limited to 5 J/cm 3 at operating conditions of 200–300 kV/mm for film capacitors in electric vehicles. To address these issues based on the multi-interface trap energy levels, we hereby design a poly(vinylidene fluoride) (PVDF) composite filled with core-shell nanoparticles of BaTiO 3 @polydopamine (BT@PDA) and sandwiched by poly(methyl methacrylate) (PMMA) layers for high low-field U dis . The coordination of deep electron traps at the PMMA/PVDF interlayer interface along with deep hole and electron traps at the PVDF/PDA interfaces can trap charges and hinder charge transport. This effectively suppresses J and significantly increases the low-field U dis , as demonstrated by interfacial energy band analysis and phase field simulations. Consequently, a high low-field U dis of 6.65 J/cm 3 at 310 kV/mm was achieved on this PMMA-BDP-PMMA nanocomposite, along with a low dielectric loss of 0.037 and a low J of 3.88 × 10 −7 A/cm 2 at 25 kV/mm and a high energy efficiency of 66 %. It represents an effective approach to improving the energy storage performance of polymer dielectrics at low fields.
研究领域:
材料科学
·
能源存储
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Qitong Wang,Tianze Wang,Hui Chi,Danying Zhao,Lixuan Yu,Zhenhua Jiang,Yunhe Zhang
Polymer dielectrics are key component for energy storage capacitors in modern electronical equipment with their high breakdown strength, great reliability and processable for large-scale manufacture. However, deteriorated capacitive performance due to dramatically increased conductive loss at elevated temperature fails polymer dielectrics to meet the rising demand for harsh working environment. Herein, a novel thermosetting polymer benzoxazines (BZ) is selected, and a serial of polyetherimide (PEI)/benzoxazines (BZ) dielectric films designed with rich traps are prepared for high temperature capacitive application. The density functional theory (DFT) simulations have revealed that energy barrier can be formed based on the difference in energy band structure of BZ and PEI. Constructed concurrently with dense cross-linking network formed by the polymerization of benzoxazines monomers, PEI/BZ composites can exhibits great capability in restraining the charge transport, suppressing the leakage current density, therefore endowing a significant improvement in energy storage density at elevated temperature. At 150 °C, the PEI/5 wt% BZ composite processes energy storage density ( U e ) as high as 4.64 J cm −3 with charge–discharge efficiency of 92 % at 550 MV m −1 , representing a 2.3-fold increase compared to pure PEI, and capacitive reliability of 50,000 cycles at 400 MV m −1 . Notably, integrated with the controllability of BZ monomer, straightforward film fabrication and the over-all low cost, this design strategy have shed a bright light in the industrial manufacture of high-temperature capacitive materials with superior energy storage performance.
研究领域:
材料科学
·
电子工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）