ADVANCED SYNTHESIS & CATALYSIS
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2026
·Vol. 368
·期 9
·e70446
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IF 3.7
Dingbin Zhu,Yue Wang,Fuxiu Cao,Wanjun Xu,Wenlong Jia,Huai Liu,Rui Zhang,Lincai Peng,Tianping Lv,Tianwei He,Junhua Zhang
The photocatalytic conversion of biomass-derived monosaccharides to lactic acid (LA) provides a sustainable approach for the high-value utilization of biomass. However, conventional photocatalysts suffer from insufficient visible light absorption, rapid recombination of photogenerated charge carriers, and inadequate surface active sites, which severely hinder the generation of key active species, thereby limiting the catalytic activity and LA selectivity. Herein, this study constructs a Z-scheme heterojunction photocatalyst TiO 2 /C-CN by combining carbon skeleton and oxygen vacancy (V O )–modified TiO 2 with graphitic carbon nitride (CN), with excellent photocatalytic performance. Under visible light irradiation, it achieves 92.3% LA yield and 96.4% selectivity within 60 min. The carbon skeleton effectively enhances visible light absorption and electron transport, V O provides abundant active sites for the adsorption and activation of oxygen, and the construction of the Z-scheme heterojunction achieves efficient charge separation while retaining strong redox capability. The synergistic effect of these three components facilitates the efficient generation of superoxide radicals ( ), which selectively cleave the C3 C4 bond of glucose intermediates, directing the reaction toward LA formation. This study provides a rational strategy to design efficient and precise photocatalysts for biomass valorization through the synergistic regulation of electron transport channels, defect sites, and heterojunction engineering.
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SENSORS AND ACTUATORS B-CHEMICAL
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2026
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IF 8.3
Huan Li,Zhiguang Suo,Xueqing Zhu,Min Wei,Huali Jin,Rui Guo,Yong Liu,Renyong Zhao
The widespread misuse of ciprofloxacin (CIP) poses a serious threat to environmental safety and human health, necessitating its trace detection in food matrices. In this study, a novel electrochemical aptasensor was developed for the highly sensitive detection of CIP. Au@ZnCoN-C nanocomposites with superior conductivity were synthesized and employed as the electrode modification material. To improve assay sensitivity, a target-triggered cyclic amplification method relying on RecJf exonuclease was adopted. Notably, a cross-linked DNA framework (CLDF) was utilized for the first time in CIP detection. Its interconnected architecture provides abundant active sites for high-density loading of methylene blue (MB), thereby significantly amplifying the electrochemical response. Under optimized conditions, the aptasensor exhibited a wide linear range from 0.005 to 1000 ng/mL, with a low limit of detection (LOD) of 3.2 pg/mL. Furthermore, the sensor was successfully applied to the analysis of CIP in milk, egg, and pork samples with satisfactory results. Leveraging its high specificity, long-term stability, and high sensitivity, this method provides a robust strategy for the precise monitoring of CIP in food safety applications.
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LWT-FOOD SCIENCE AND TECHNOLOGY
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2026
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IF 7.1
Jingyi Xiao,Yiwei Liu,Shuaihao Guo,Weinong Zhang,Zongyuan Wu,Jiangtao Feng,Yanxia Cong,Xinghao Tu
Phosphatidylinositol (PI) is vital for studying metabolic diseases and cancer; however, its purification is challenging. An enzymatic-chromatographic approach for producing high-purity PI from concentrated soybean phospholipids was developed in this study. This method employs phospholipase C (PLC), which selectively hydrolyses phosphatidylcholine (PC) and phosphatidylethanolamine (PE) but leaves PI intact. This selective reaction serves as a critical pretreatment step for enriching PI content in mixtures. The optimal reaction conditions included a SCPs to water ratio of 1:1.57 (g/mL), temperature of 39.6 °C, PLC dosage of 22 mg/g, and reaction time of 3.3 h, complete hydrolysis of PE and PC was achieved. Subsequently, defatting and deglycosylation the hydrolysed phospholipids concentrated the PI from 152.90 to 513.30 mg/g. This step markedly facilitated the downstream PI purification process. Chloroform-methanol volume ratio (1.8:1) chromatography at a flow rate of 8 mL/min was used to purify the PI further, yielding a high-purity product with a purity of 91.86 g/hg and yield of 77.85 g/hg. High-purity PI is suitable for medical applications owing to its lipid properties. This efficient purification strategy paves the way for the development of new therapeutics.
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CERAMICS INTERNATIONAL
·
2026
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IF 6
Yu Deng,Peiyuan Zhang,Xiaoshan Zhang,Chong Wang,Tianqi You,Ruizhang Wang,Lei Zhao,Zheng Zhang,Feilou Wang,Nana Xu,Xiaozhou Wang
Carbon nanofibers (CNFs) possess advantages such as high strength, high-temperature resistance, and high extinction coefficient, making them widely used in aerospace, industrial furnaces, and energy fields. However, the high solid thermal conductivity of CNFs limits their application in high-temperature thermal insulation. To address this issue, we propose simultaneously constructing porous structure and introducing low-thermal-conductivity zirconia (ZrO 2 ) nanocrystals into CNFs to prepare “lotus-root-like” porous ZrO 2 /C nanofibers (ZrO 2 /C-NFs). The ZrO 2 /C-NFs achieved ultra-low thermal conductivity of 0.013 W m −1 K −1 at ambient and 0.077 W m −1 K −1 at 1200 °C, representing reductions of 27.8% and 76.7% compared to solid ZrO 2 /C-NF membranes, respectively. In addition, the ZrO 2 /C-NFs exhibited excellent mechanical property and thermal stability. The tensile strength of ZrO 2 /C-NFs membrane was up to ∼2.2 MPa. The mass retention maintains over 85% even heated at 1400 °C in an argon atmosphere. The integrated properties of the ZrO 2 /C-NFs make them have great promising application in the field of high-temperature thermal insulation. This study also provides a novel approach for designing and fabricating high-performance thermal insulation materials.
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CANCER LETTERS
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2026
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IF 11.8
Shuangshuang Ma,Minxin Chen,Xiaozheng Sun,Baochao Wei,Fengxin Sun,Xueqi Xie,Yiheng Huang,Zhaoyun Liu,Rong Xiao,Ling Wei,Fei Wang,Ying Xu,Jinming Yu,Dawei Chen,Meng Wu
Tamoxifen has been commonly used in endocrinotherapy for estrogen receptor (ER)-positive breast cancer. In recent years, the immunomodulatory effects of high-dose tamoxifen have been discovered. The immunosuppressive tumor microenvironment (TME), however, remains a major obstacle to the efficacy of radiotherapy. Whether high-dose tamoxifen can reprogram TME to synergistically enhance radiation efficacy is still ambiguous. Here, we have found high-dose tamoxifen could dramatically enhance radiation-induced antitumor effects without significant side effects in immunocompetent mice. Flow cytometry and multiplex immunofluorescence experiments revealed that radiation combined with tamoxifen resulted in significant enrichment of effector CD8 + T cells and M1 tumor associated macrophages (TAMs). While depletion of TAMs and CD8 + T cells impaired the synergistic antitumor effects mediated by combination treatment of radiation and tamoxifen. Furthermore, spatial proximity analysis demonstrated a dramatically reduced nearest-neighbor distance between CD8 + T cells and M1-like TAMs in the combination group, indicating enhanced cellular interaction within the TME. In vitro experiments demonstrated that tamoxifen directly acted on TAMs, rather than CD8 + T cells, to promote M1 polarization and subsequently enhanced the activation and effector function of CD8 + T cells, regardless of ER expression in tumor cells and macrophages. Mechanistically, RNA-sequencing and experimental validation uncovered that tamoxifen and tumor cell-derived TNF-α and IL-1β after irradiation synergistically activated the JNK/c-JUN pathway and promoted M1 polarization of TAMs. In conclusion, our study revealed the immunomodulatory effects of high-dose tamoxifen in the context of radiation and provided preclinical evidence for combination therapy of high-dose tamoxifen and radiotherapy in both ER-positive and ER-negative cancers.
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PubMed
高影响因子
APPLIED SURFACE SCIENCE
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2026
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IF 6.6
Yuanhao Mao,Chunfeng Mao,Xincai Chen,Run Qian,Ziyi Wang,Lanjing Zhao,Pengxu Yan,Yuxi Zhang
The surface of the C shell is covered with mesoporous channels, which promotes the occurrence of the confinement effect. • The abundant hydroxyl groups enable the C shell not only to exert physical adsorption but also to cooperate with chemical adsorption. • Both the dual transition metal regulation mechanism and the electron cooperative mechanism can be applied in ODS. • The desulfurization rate (99.53%) can be achieved under the mild reaction condition with less dosages of catalysts and ILs. • EPR analysis and radical scavenging assay experiments confirmed that one type of free radicals acts in the ODS. Common transition metal catalysts have been widely applied in catalytic reaction. However, the shortcomings in electronic regulation mechanism, confinement effect, and synergistic adsorption remain to be urgently addressed. This study designed a dual-transition-metal-based catalyst (Mo-W@C) with a surface rich in hydroxyl functional groups. Its bimetallic active components are obtained through protonation reaction. The C shell is coated on the bimetallic active components through self-assembly and directional anchoring. These procedures reduce the interatomic distance between Mo and W in the bimetallic active component, enhancing the electronic interaction between them. The confinement effect of the C shell accelerates the collision of reaction molecules. Furthermore, the abundant hydroxyl groups on the surface of the C shell facilitate the rapid adsorption of H 2 O 2 . A high sulfur removal rate of Mo-W@C (99.56 %) was achieved under mild reaction conditions (V(ILs) = 0.1 mL, m(catalyst) = 10 mg, V(H 2 O 2 ) = 0.15 mL, 80 °C, 90 min). Moreover, the catalyst still maintained a high desulfurization rate (95.76 %) after seven cycles. The catalytic reaction mechanism involving peroxide state and electronic synergy was elucidated by experiments and analyses (XPS, EPR, etc.). This catalytic structure provides a new perspective for the research on supported catalysts. Download: Download high-res image (151KB) Download: Download full-size image
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2026
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IF 9.2
Yubin He,Shuting Zhang,Xiu Yu,Jiamiao Lu,Hairen Tang,Shiyang Qin,Xudong Xiao,Kun Lang,Yanhong Zhang,Baojiang Jiang
Bifunctional seawater electrolysis is limited by the activity–durability trade-off in chloride-containing media. Here, in-situ-grown Co-BTC MOF arrays on nickel foam were converted into self-supporting CoP/Co 2 P-C/NF electrodes, enabling controlled evolution Co 2 P-rich to CoP-rich compositions and identifying a favourable CoP/Co 2 P coexistence range. The continuous conductive carbon framework shortens charge-transport paths, maintains electrolyte–electrode contact, and supports rapid interfacial kinetics. Theoretical calculations indicate that the CoP/Co 2 P biphasic interface modulates intermediate adsorption, weakening Cl adsorption while favouring water-splitting-related intermediates, consistent with suppressed chlorine-related competition. At 10 mA cm −2 in 1.0 M KOH, the optimized electrode requires 31 mV for hydrogen evolution reaction (HER) and 180 mV for oxygen evolution reaction (OER), and drives overall water splitting at 1.47 V with stable operation over 100 h at 1.56 V. In 1.0 M KOH + seawater, it maintains low voltage and outperforms Pt/C||RuO 2 , providing a reproducible phase-ratio regulation strategy for non-precious bifunctional seawater electrolysis electrodes.
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DIAMOND AND RELATED MATERIALS
·
2026
·
IF 5.2
Muhammad Ali Hamza Shahbaz,Madaminov Sanjarbek Maxmudjon ugli,Hamid Nasir,Maryam Al Huwayz,Muneerah Alomar,Amir Muhammad Afzal,Sohail Mumtaz,Abhinav Kumar
Dysprosium cobalt oxide (DCO)-graphitic carbon nitride (gCN)-MXene hybrid nanocomposites were synthesized with a simple hydrothermal technique for advanced energy storage and catalysis devices. The result of XRD, SEM, and XPS analyses validated that it exhibited high crystallinity, uniform morphology, and a significant amount of surface functionalities. The electrochemical testing was conducted, and the specific capacity (Qs) is estimated to be 1865.9C g −1 at 3 mV s −1 , while the hybrid supercapacitor has a Qs of 280.04C g −1 , energy density (Ed) of 45 Wh kg −1 , and power density (Pd) of 2836 W kg −1 . Furthermore, the composite showed a remarkable electrocatalytic activity with an overpotential of 69 mV and the Tafel slope of 64 mV dec −1 , which indicates that it has good charge transfer property. The findings prove that DCO@MXene@gCN is an electroactive material with multifunctional properties suitable for novel and advanced energy systems. Download: Download high-res image (176KB) Download: Download full-size image
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CHINESE JOURNAL OF CATALYSIS
·
2026
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IF 17.2
Chongzheng Xu,Haoping Di,Fengyue Sun,Wenjing Bao,Yanwei Ju,Dengwei Yan,Changle Yue,Yiyuan Xu,Yunxiu Zhao,Shuo Wang,Jiqian Wang,Yukun Lu
Sulfided NiMo catalysts can effectively hydrogenate oxygen-rich bio-oils into high quality hydrocarbon fuels. However, precisely controlling the cleavage of C−O bonds remains challenging. Here, we synthesized an oil-soluble precursor NiMo 6 -DODA by encapsulating the polyoxometalates (POMs) (NH 4 ) 4 [NiMo 6 O 24 H 6 ] (NiMo 6 ) with surfactants, followed by in-situ construction of an ultra-dispersed monolayer NiMoS catalyst. The “surfactant shell” of the precursor ensured its homogeneous dispersion in the oil phase, while gradually sacrificing and decomposing during the sulfidation to mitigate the aggregation of the MoS 2 nanosheets. Meanwhile, the well-defined “POMs core” established an atomic-level Ni-Mo proximity, ensuring the dominance of the Ni-promoted MoS 2 active phase. This design not only altered the adsorption configuration of esters on the NiMo catalyst but also introduced abundant edge sulfur vacancies to promote oxygen atom adsorption and accelerate C−O bond cleavage. The results showed that NiMo 6 -DODA achieved 100% conversion of methyl palmitate and 100% alkane selectivity under low catalyst loading conditions. Notably, the selectivity for n -hexadecane reached 94.2%, significantly surpassing that obtained with a commercial oil-soluble precursor (69.8%). Furthermore, the catalyst maintained high activity across multiple reaction cycles and in the solvent-free conversion of real bio-oils. This strategy of pre-assembly combined with sacrificial sulfidation provides a simple and effective route for designing hydrodeoxygenation catalysts that enable precise control over ester C−O bond cleavage.
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CARBON
·
2026
·
IF 12.7
Huimin Xie,Wenhui Liu,Linkun Wu,Liping Zhang,Yuxiang Wang,Zaizhe Cheng,Xiucheng Sun,Shuhao Wei,Guojun Lan,Ying Li
Ni-phyllosilicate hard-templating yields sintering-resistant mesoporous Ni–C catalysts. • Achieves high-loading, ultrafine Ni NPs via a confined interfacial layer. • Enhanced SMSI and anti-leaching stability are confirmed by multi-technique analysis. • Superior LA-to-GVL hydrogenation: 99.7% conversion, 99.3% selectivity. • A general design for high-performance non-noble metal-carbon hydrogenation catalysts. Carbon-encapsulated metal catalysts prepared by in-situ carbonization generally suffer from severe metal sintering during high-temperature treatment. Herein, we develop a nickel phyllosilicate-assisted hard-templating strategy to construct mesoporous Ni–C catalysts with ultrafine, high-loading Ni nanoparticles partially embedded in the carbon support. A Ni 3 Si 2 O 5 (OH) 4 interfacial layer is pre-formed via ammonia evaporation prior to carbonization, which effectively inhibits Ni sintering and strengthens the metal-support interaction. The embedded structure generates charge-polarized Ni δ+ –Ni δ– sites that promote hydrogen dissociation and spillover, and enable synergistic activation of levulinic acid and H 2 . Under mild conditions (S/C = 50, 160 °C, 1 MPa H 2 ), the optimized Ni–C–p catalyst achieves 99.7% LA conversion and 99.3% γ-valerolactone selectivity within 2 h, with a reaction rate approximately three times that of conventional impregnated Ni/C. This strategy exhibits good universality for designing other non-noble metal-carbon composites toward challenging liquid-phase hydrogenation reactions. Download: Download high-res image (290KB) Download: Download full-size image
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JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2025
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IF 3.8
Sheng Li,Junjie Shi,Yuchao Qiu,Yongyi Zhou,Xiaoyu Gong,Hongjian Tang,Dong Li,Xiao Sai,Jianzhang Li
Phase relationships in the Yb 2 O 3 –Al 2 O 3 –SiO 2 system are critical for the design and corrosion protection of environmental barrier coatings (EBCs), the available data remain scarce and primarily limited to studies from the 1990s. The isothermal phase diagram of the Yb 2 O 3 –Al 2 O 3 –SiO 2 system at 1600°C was conducted using a classical high-temperature equilibrium quenching technique, followed by XRD, SEM, and EPMA phase analysis. The data were reported in the form of liquidus projections and an isothermal phase diagram at 1600°C, with one single-phase region, six two-phase regions, and seven three-phase regions. A comparison of the liquid phase regions at 1550°C and 1600°C revealed a systematic expansion with increasing temperature, consistent with thermodynamic expectations. The experimental results from the present work are essential for the development of a thermodynamic database for rare earth oxides, providing vital guidance for designing next-generation EBCs.
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RARE METALS
·
2025
·
IF 11
Chen Taoran,Qin Tian,Sun Hongli,Su Chenliang
Photocatalytic oxidation of toluene to valuable benzaldehyde offers a promising pathway for sustainable production of fine chemicals and pharmaceuticals. In this process, photogenerated holes play a crucial role in C(sp 3 )-H bond dissociation. However, the photocatalytic performance of current photocatalysts is often hindered by the low separation and transfer efficiency of photogenerated charges. In this work, we presented a perovskite-based heterostructure via in situ growth of defective WO 3- x nanosheets on Cs 2 AgBiBr 6 nanoparticles for photocatalytic toluene transformation. In situ Fourier transform infrared spectroscopy tests proved the introduction of oxygen-deficient WO 3- x component enhanced the chemisorption of molecular oxygen. The in situ electron paramagnetic resonance and 4-chloro-7-nitro-1,2,3-benzoxadiazole fluorescence measurements further confirmed the presence of oxygen vacancies, and the formation of heterostructure synergistically accelerated the formation of the superoxide radicals and the transfer of photogenerated charge carriers. Under visible light irradiation, Cs 2 AgBiBr 6 /WO 3- x photocatalyst could effectively oxidize toluene toward benzaldehyde with a conversion rate of 9020 μmol g −1 h −1 , which was a 3.5-fold increase over that of the unmodified Cs 2 AgBiBr 6 . Graphical abstract
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危险品化学品经营许可证（带存储）