BIOSENSORS & BIOELECTRONICS
·
2018
·
IF 8.173
Guifen Jie,Junjun Ge,Xiaoshan Gao,Chunli Li
In this work, we designed a new strategy for ultrasensitive detection of CEA based on efficient electrochemiluminescence (ECL) quenching of Ru(bpy) 3 2+ -doped SiO 2 nanocomposite by ferrocene using target recycling amplification technique. A large number of [email protected] 2 ECL signal probe were firstly assembled on the novel magnetic core−shell Fe 3 O 4 @Au nanoparticles (NPs), then the ferrocene-labeled ECL quenching probe (Fc-probe) was linked to the magnetic NPs. Finally, numerous DNA1 sequences were produced by target CEA-triggered multiple recycling amplification and displaced the Fc-probe on the magnetic NPs, leading to significantly enhanced ECL signal for CEA detection. Because of the designed cascade signal amplification strategy, the newly developed method achieved a wide linear range of 10 fg/mL to 10 ng/mL with a low detection limit of 3.5 fg/mL. Furthermore, taking advantages of the magnetic Fe 3 O 4 @Au NPs for carring abundant signal probes, sensing target and ECL detection, the developed ECL strategy is convenient, rapid and displayed high sensitivity for CEA detection, which has great potential for analyzing the clinical samples in practical disease diagnosis applications.
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DOI
PubMed
高影响因子
Journal of Environmental Sciences
·
2023
·
IF 6.9
Linchun Nie,Shuangying Li,Xiaozhong Gao,Shuai Yuan,Guangyu Dong,Guojin Tang,Denghao Song,Lutong Bu,Qingxiang Zhou
Norfloxacin is widely used owing to its strong bactericidal effect on Gram-negative bacteria. However, the residual norfloxacin in the environment can be biomagnified via food chain and may damage the human liver and delay the bone development of minors. Present work described a reliable and sensitive smartphone colorimetric sensing system based on cobalt-doped Fe 3 O 4 magnetic nanoparticles (Co-Fe 3 O 4 MNPs) for the visual detection of norfloxacin. Compared with Fe 3 O 4 , Co-Fe 3 O 4 MNPs earned more remarkably peroxidase-like activity and TMB (colorless) was rapidly oxidized to oxTMB (blue) with the presence of H 2 O 2 . Interestingly, the addition of low concentration of norfloxacin can accelerate the color reaction process of TMB , and blue deepening of the solution can be observed with the naked eye. However, after adding high concentration of norfloxacin, the activity of nanozyme was inhibited, resulting in the gradual fading of the solution. Based on this principle, a colorimetric sensor integrated with smartphone RGB mode was established. The visual sensor exhibited good linearity for norfloxacin monitoring in the range of 0.13-2.51 µmol/L and 17.5-100 µmol/L. The limit of visual detection was 0.08 µmol/L. In the actual water sample analysis, the spiked recoveries of norfloxacin were over the range of 95.7%-104.7 %. These results demonstrated that the visual sensor was a convenient and fast method for the efficient and accurate detection of norfloxacin in water, which may have broad application prospect.
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DOI
高影响因子
NANOTECHNOLOGY
·
2017
·Vol. 28
·期 40
·405101
·
IF 3.44
Qi Zhang,Jian Liu,Kunjie Yuan,Zhengguo Zhang,Xiaowen Zhang,Xiaoming Fang
Herein a novel multi-controlled drug release system for doxorubicin (DOX) was developed, in which monodisperse mesoporous Fe3O4 nanoparticles were combined with a phase change material (PCM) and polyethylene glycol 2000 (PEG2000). It is found that the PCM/PEG/DOX mixture containing 20% PEG could be dissolved into water at 42 °C. The mesoporous Fe3O4 nanoparticles prepared by the solvothermal method had sizes of around 25 nm and exhibited a mesoporous microstructure. A simple solvent evaporation process was employed to load the PCM/PEG/DOX mixture on the mesoporous Fe3O4 nanoparticles completely. In the Fe3O4@PCM/PEG/DOX system, the pores of the Fe3O4 nanoparticles were observed to be filled with the mixture of PCM/PEG/DOX. The Fe3O4@PCM/PEG/DOX system showed a saturation magnetization value of 50.0 emu g−1, lower than 71.1 emu g−1 of the mesoporous Fe3O4 nanoparticles, but it was still high enough for magnetic targeting and hyperthermia application. The evaluation on drug release performance indicated that the Fe3O4@PCM/PEG/DOX system achieved nearly zero release of DOX in vitro in body temperature, while around 80% of DOX could be released within 1.5 h at the therapeutic threshold of 42 °C or under the NIR laser irradiation for about 4 h. And a very rapid release of DOX was achieved by this system when applying an alternating magnetic field. By comparing the systems with and without PEG2000, it is revealed that the presence of PEG2000 makes DOX easy to be released from 1-tetradecanol to water, owing to its functions of increasing the solubility of DOX in 1-tetradecanol as well as decreasing the surface tension between water and 1-tetradecanol. The novel drug release system shows great potential for the development of thermo-chemotherapy of cancer treatment.
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DOI
高影响因子
ADVANCED ENGINEERING MATERIALS
·
2024
·Vol. 26
·期 12
·2400059
·
IF 3.4
Chuangji Liu,Yingjie Xu,Beiqing Huang,Wan Zhang,Xingyu Zhao,Yuxin Wang
Multiwalled carbon nanotube (MWCNT)/polypyrrole nanotube (PPyNT)/triiron tetraoxide (Fe 3 O 4 ) composites with a sword-sheath structure are added to a UV-curable resin to form a unique highly microwave-absorbing material with a low absorbent content. Specifically tailored for high-precision stereolithography three-dimensional (3D) printers, the low absorbent content ensures an efficient curing and molding of the photosensitive resin. The conducting polymer polypyrrole is coated on the MWCNTs via free-radical polymerization, forming a sheath structure. The initiator of the free-radical polymerization, FeCl 3 , is converted into Fe 3 O 4 and loaded onto the sheath structure. This ternary composite material is uniformly dispersed in the photosensitive resin with interconnected sword-sheath structures, ensuring a favorable dielectric loss performance even at a low absorbent content. Importantly, the material exhibits both dielectric loss and magnetic loss properties. Using a UV-cured microwave-absorbing material with an absorbent content of 0.5 wt%, an electromagnetic loss of −22.5 dB can be achieved with a thickness of 1 mm. This UV-cured microwave-absorbing material facilitates the high-precision 3D printing of microwave structures with various intricate shapes, broadening the application scope of microwave-absorbing materials.
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DOI
高影响因子
Desalination and Water Treatment
·
2024
·
IF 1
Dezhi Qin,Guangrui Yang,Li Zhang
The Al-doped Fe 3 O 4 /hydroxyapatite (HAP) nanocomposites prepared in pectin matrix was employed as adsorbent that offers high adsorption capacity for fluoride, magnetic separability and good stability. Powder X-ray diffraction and transmission electron microscopy characterizations were used to determine the structure and morphology of as-prepared samples. The needle-like Al-doped Fe 3 O 4 /HAP nanocrystals were coated with pectin molecules, which not only induced the nucleation, but inhibited the further growth of nanocrystals. The results of thermogravimetric analysis and Fourier transform infrared spectra showed that the obtained products are organic–inorganic nanocomposites; and the Al doping in composites increased the amount of hydroxyl groups, which could supply more adsorption sites for fluoride. In bath experiments, the adsorption capacity of Al-doped samples was significantly higher than that of pure HAP due to the high affinity of aluminium toward fluoride. The effect of reaction parameters such as pH, calcination temperature, co-existing anions and Al/Ca molar ratio on the adsorption capacity was also investigated to determine optimum adsorption condition. The Al-doped Fe 3 O 4 /HAP nanocrystals exhibited high adsorption rate for fluoride during the first 30 min and reached equilibrium within 80 min. The adsorption kinetics and isotherms were well-fitted by the pseudo-second-order kinetic model and the Freundlich isotherm model, respectively. In addition, the adsorption mechanism of fluoride on Al-doped Fe 3 O 4 /HAP nanocomposites was investigated, which can be mainly attributed to electrostatic attraction and ion-exchange.
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DOI
高影响因子
NANOTECHNOLOGY
·
2019
·Vol. 30
·期 33
·335701
·
IF 3.399
Fei Wang,Chuqing Wang,Hong Chen,Wenlong Zhang,Rujia Jiang,Zhanheng Yan,Zhongyuan Huang,Haihui Zhou,Yafei Kuang
The iron oxide-based anode materials are widely studied and reported due to their abundance, low cost, high energy density and environmental friendliness for lithium ion batteries (LIBs). However, the application of LIBs is always limited by the poor rate capability and stability. In order to tackle these issues, a novel material with carbon-encapsulated Fe3O4 nanorods stuck together by multilevel porous carbon (Fe3O4@C/PC) is prepared through directly carbonizing the Fe-based metal-organic framework under a nitrogen atmosphere. This novel material shows a high specific capacity and rate performance. The initial specific capacity can reach 1789 mAh g−1 at a current density of 0.1 A g−1, and the specific capacity still remains 1105.3 mAh g−1 and 783.5 mAh g−1 after 150 cycles at the current densities of 0.1 A g−1 and 1 A g−1, respectively. Even under a current density as high as 12 A g−1, the specific capacity can achieve 309 mAh g−1 after 2000 cycles with an average attenuation rate of 0.019% per cycle. Overall, the simple strategy, low cost and high capacity can make the practical application possible.
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DOI
高影响因子
ELECTROCHIMICA ACTA
·
2015
·
IF 4.504
Dekang Huang,Yanping Luo,Shaohui Li,Mingkui Wang,Yan Shen
To realize a large-scale application of fuel cells, it is highly desirable to develop noble metal-free electrocatalysts for oxygen reduction reaction (ORR). Herein, a highly active electrocatalyst is synthesized by impregnating in situ generated iron(III)-1,10-phenanthroline complex on commercially high specific surface area carbon blacks and subsequent pyrolysis at high temperature. High ORR limiting current density (5.79 mA cm −2 ) and positive half-wave potential (0.859 V versus RHE) over this electrocatalyst with a mass loading of 0.2 mg cm −2 can be achieved in 0.1 M KOH solution, which are very comparable with the benchmark Pt/C electrocatalyst. Detailed investigations have revealed the existence of nitrogen doped carbon (N-C), nitrogen coordinated to Fe (Fe-N), and Fe@Fe 3 O 4 core-shell nanoparticles in this composite electrocatalyst. The high activity of this electrocatalyst is attributed to the synergistic effect among them.
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DOI
高影响因子
Journal of Physical Chemistry C
·
2012
·
IF 4.805
Qiao An,Meng Yu,Yuting Zhang,Wanfu Ma,Jia Guo,Changchun Wang
The heterostructure Ag–Au bimetallic nanocrystals supported on Fe3O4@carbon composite microspheres were synthesized by one facile and controllable approach, wherein the Ag nanocrystals attached on the Fe3O4@carbon microspheres were prepared first and served as reductant for the galvanic replacement reaction with the Au precursor (HAuCl4). Upon varying the feeding amounts of the Au precursor, the bimetallic compositions on the Fe3O4@carbon microsphere could be readily tuned resulting in a series of composite microspheres with different Au-to-Ag molar ratios. Subsequently, we thus investigated the catalytic activity and selectivity of the magnetic composite catalysts from two sides. First, 4-nitrophenol (4-NP) was applied as a model molecule to study the effect of different Au-to-Ag molar ratios on catalytic capabilities of the resulting composite microspheres. It was found that upon the addition of NaBH4 the catalytic capability was markedly enhanced when the Au content was increased. The maximum activity parameter value reached 1580 s–1 g–1, which is far higher than those of known monometallic composites. Also, they could give the equally high yields for other nitroaromatic compounds with various substituents, irrespective of the linked electron-donating or electron-withdrawing groups. Second, the synergistic effects of the carbon substrate in the catalysis reaction were demonstrated. When compared with colloidal SiO2, TiO2, and poly(styrene-co-acrylic acid) substrates, the carbon support not only facilitated the enhancement of the catalytic performance of the noble metal nanocrystals but was also more suitable for the in situ preparation of Au–Ag bimetallic nanocrystals using the GRR. Besides, the particles’ convenience in terms of their magnetic separability and outstanding reusability was validated through many successive reduction reaction cycles. In light of these unique characteristics, the Fe3O4@C@Ag–Au composite microspheres show promising and great potential for practical applications.
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DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2013
·
IF 2.112
Yaohui Xu,Yang Zhou,Wenhui Ma,Shixing Wang,Shaoyuan Li
The Fe 3 O 4 nanoparticles [NPs] coated with silica nanoparticles were designed to produce magnetic core–shell Fe 3 O 4 @SiO 2 NPs, which were modified with rhodamine B derivatives and defined as Fe 3 O 4 @SiO 2 -Rho NPs. The obtained Fe 3 O 4 @SiO 2 -Rho NPs served as a fluorescent OFF-ON nanosensor was utilized to detect Zn 2+ selectively in acetonitrile medium. The Fe 3 O 4 @SiO 2 -Rho NPs exhibited selective “turn-on” type fluorescent enhancements and distinct color changes with Zn 2+ . The Fe 3 O 4 @SiO 2 -Rho NPs also showed a high capacity for removal of Zn 2+ at room temperature. The removal efficiency toward Zn 2+ was about 87.34%. In addition, the presence of magnetic Fe 3 O 4 particles as core in Fe 3 O 4 @SiO 2 -Rho NPs could facilitate the magnetic separation of the Fe 3 O 4 @SiO 2 -Rho-Zn 2+ from the solution.
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DOI
高影响因子
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
·
2014
·Vol. 2014
·期 20
·3172-3177
·
IF 2.965
Zhiming Chen,Zhirong Geng,Zhiyang Zhang,Lianbing Ren,Tingxian Tao,Renchun Yang,Zuxiang Guo
Graphical Core–shell magnetic Fe 3 O 4 @C nanoparticles are functionalized with sulfonic and carboxylic acid groups and employed to capture heavy metal ions in aqueous media. The magnetic Fe 3 O 4 @C nanoparticles can be easily separated with an external magnet and possess rapid removal kinetics, high adsorption capacities, and removal efficiencies for Pb 2+ , Hg 2+ , and Cd 2+ ions from aqueous solution. Core–shell magnetic Fe 3 O 4 @C nanoparticles functionalized with sulfonic and carboxylic acid groups were synthesized and employed to capture heavy metal ions in aqueous media. The Fe 3 O 4 cores possess unique magnetic properties for adsorbent separation, and the –SO 3 H and –COOH groups attached to the surface of the carbon shells determine the efficiency of heavy metal ion removal. Batch adsorption experiments showed that Pb 2+ , Hg 2+ , and Cd 2+ ions can be completely and quickly removed by the Fe 3 O 4 @C nanoparticles. The equilibrium was established within 5 min, and the maximum adsorption capacities of the Fe 3 O 4 @C nanoparticles toward Pb 2+ , Hg 2+ , and Cd 2+ ions were 90.7, 83.1, and 39.7 mg/g, respectively. The removal efficiencies were 96.3, 98.1, and 93.8 % for Pb 2+ , Hg 2+ , and Cd 2+ ions, respectively. This work provides a facile and general approach to synthesize magnetic functional nanocomposites for wastewater treatment.
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DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2022
·
IF 6.911
Shitao Feng,An Zhang,Fengshou Wu,Xiaogang Luo,Juan Zhang
In this study, a novel core-shell structured magnetic metal-organic framework nanospheres (Fe 3 O 4 @PD@BA-Zr-MOF) were fabricated by in-situ growth of boronic acid-decorated porphyrin-based metal-organic frameworks on polydopamine (PD) functionalized Fe 3 O 4 nanospheres for highly efficient enrichment of cis -diol containing nucleosides by magnetic solid phase extraction (MSPE). PD as a molecular linker promotes the nucleation and crystal growth of boronic acid-decorated porphyrin-based metal-organic framework (BA-Zr-MOF), which was synthesized via a dual-ligand strategy by using Zr 4+ as a metal unit as well as meso-tetra (4-carboxylphenyl) porphyrin (TCPP) and 1, 4-phenylenebisboronic acid (BA) as dual organic ligands. It is worth noting that the nitrogen-rich skeleton of TCPP and abundant boric acid groups in MOF allows for effective and selective enrichment of cis -diol containing compounds by hydrophilic interaction and boron affinity. Also, Zr 4+ well assembled into the MOF is beneficial to extraction via metal oxide affinity interaction due to reversible covalent complex formation/dissociation between Zr and cis -diol compounds. The morphology, structure and saturation magnetization of Fe 3 O 4 @PD@BA-Zr-MOF were systematically characterized. The as-prepared adsorbent coupled with high performance liquid chromatography was used for analysis of four nucleosides including cytidine , uridine , guanosine , and adenosine in urine sample with the detection limits in range of 0.002–0.005 μg mL −1 and the quantitative limits in range of 0.008–0.018 μg mL −1 . The as-fabricated Fe 3 O 4 @PD@BA-Zr-MOF nanospheres shows high selectivity , low detection limit, excellent reusability and reproducibility for nucleosides enrichment. The large specific surface area and quick magnetic response performance endow the affinity magnetic nanospheres with outstanding enrichment capability for rapid extraction. The adsorbent of Fe 3 O 4 @PD@BA-Zr-MOF nanospheres has great potential for identification and analysis of trace cis -diol containing nucleosides in biological samples.
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DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2020
·
IF 7.1
Meng Wang,Xianwen Kan
A novel dual-modal sensing interface was constructed for the electrochemical/colorimetric dual-modal sensing of aloe-emodin (AE). Fe 3 O 4 micro-particles were directly synthesized on a multi-layer exfoliated graphite paper (EGP) by the in-situ hydrothermal approach, which was subsequently modified with a layer of molecularly imprinted polymer (MIP) using pyrrole and aloe emodin (AE) as monomer and template, respectively. Due to the specific recognition ability of MIP, the prepared sensing interface showed a good selectivity to AE. The advantages of the multi-layer EGP, such as the large surface area and the excellent conductivity, enabled the sensing interface to sensitively detect AE based on the electrochemical mode. Moreover, due to the peroxidase-like activity of the modified Fe 3 O 4 micro-particles, 3,3′, 5,5′-tetramethyl-benzidine can be oxidized to deep blue by the prepared sensor in the presence of H 2 O 2 . However, the rebound AE molecules in imprinted cavities blocked the activity of Fe 3 O 4 micro-particles and caused the light blue of color, which achieved the visual colorimetric assay of AE with the good sensitivity and selectivity. With the merits of easy preparation, good selectivity, and high sensitivity, the present electrochemical/colorimetric dual-modal strategy would greatly broaden the practical application of the molecular imprinting.
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高影响因子
危险品化学品经营许可证（带存储）