POSTHARVEST BIOLOGY AND TECHNOLOGY
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2024
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IF 6.4
Saiqing Xu,Shuai Ge,Ying Xie,Jing Cheng,Ke Ding,Huan Li,Hua Huang,Zisheng Luo,Yang Shan,Shenghua Ding
Postharvest fruit infection by Alternaria alternata results in significant food waste and economic losses. Methyl ferulate (MF) emerges as a safe and potent plant-derived agent against A. alternata , yet its effectiveness is hindered by poor water solubility, limiting its wide application in postharvest preservation. This study aimed to address this issue by utilizing naturally derived grapefruit essential oil (GEO) as the dissolution carrier for MF, followed by the preparation of a nanosystem to stabilize it through ultrasound-assisted methods. At 20 mg/mL MF loading, nanoemulsions (NEs) exhibited the smallest droplet size (15.66 nm), highest centrifugation stability (Ke of 2.32 %), and optimal storage stability (15.44 nm after 30 d at 4 ℃). Importantly, MF in the nanosystem (named MN) acts as an Ostwald ripening inhibitor and reduces the interfacial tension, which in turn benefits the stability of this system. In vitro , MN showed enhanced inhibition of A. alternata hyphal growth (an inhibitory rate in potato dextrose broth medium of 99.07 ± 1.32 %) and a fourfold reduction in MIC compared to free MF. MN damaged A. alternata plasma membranes and induced reactive oxygen species (ROS) oxidative stress. In vivo , MN inhibited black spot disease and toxin production of A. alternata in pears. Additionally, MN incorporated into carboxymethylcellulose sodium (CMC) prolonged the shelf life of Korla pears and cherry tomatoes by delaying weight loss and maintaining their firmness and intrinsic nutrients. Therefore, this study broadened the application of MF, offering a viable approach for postharvest preservation of fruit infected by A. alternata .
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Advanced Energy Materials
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2025
·
IF 26
Xingzhi Zhu,Xiaoyun Miao,Chu Chen,Xiaofeng Ye,Yucun Zhou,Zhaoyin Wen
Protonic Ceramic Electrolysis Cells (PCECs) enable the in situ production of hydrogen and protons via steam electrolysis, positioning them as promising reactors for environmentally friendly ammonia synthesis. However, the efficiency and stability of this process are currently constrained by the limited catalysis activity and the aggregation of conventional fuel electrodes. Herein, in situ formed Fe-Co-Ni alloy nanoparticle catalysts are designed, and find that these alloy sites significantly enhance N 2 adsorption. Selective impregnation of Fe-Co and Ni exsolution is integrate to promote the in situ formation of Fe-Co-Ni alloy catalytic sites within the fuel electrode of tubular PCECs (10 cm 2 active area). Under an applied voltage of 0.6 V, the in situ alloyed PCEC reactor reaches 2.37 × 10 −8 mol s −1 NH 3 synthesis rate at 600 °C, which is 2.1 times that of with common fuel electrode. Density functional theory calculations further reveal that alloying reduces the activation energy for nitrogen hydrogenation, thereby facilitating the reaction pathway. Moreover, the in situ formed alloy sites exhibit a strong anchoring effect, effectively preventing catalyst aggregation at high temperature and enabling stable, efficient ammonia synthesis over 250 h. This study demonstrates the significant potential of in situ alloy catalysts combined with tubular PCECs for electrochemical ammonia synthesis.
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ACS Nano
·
2022
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IF 18.027
Yaru Gong,Shihua Zhang,Yunxiang Hou,Shuang Li,Chong Wang,Wenjie Xiong,Qingtang Zhang,Xuefei Miao,Jizi Liu,Yang Cao,Di Li,Guang Chen,Guodong Tang
SnSe single crystals have gained great interest due to their excellent thermoelectric performance. However, polycrystalline SnSe is greatly desired due to facile processing, machinability, and scale-up application. Here, we report an outstanding high average ZT of 0.88 as well as a high peak ZT of 1.92 in solution-processed SnSe nanoplates. Nanosized boundaries formed by nanoplates and lattice strain created by lattice dislocations and stacking faults effectively scatter heat-carrying phonons, resulting in an ultralow lattice thermal conductivity of 0.19 W m–1 K–1 at 873 K. Ultraviolet photoelectron spectroscopy reveals that Ge and In incorporation produces an enhanced density of states in the electronic structure of SnSe, resulting in a large Seebeck coefficient. Ge and In codoping not only optimizes the Seebeck coefficient but also substantially increases the carrier concentration and electrical conductivity, helping to maintain a high power factor over a wide temperature range. Benefiting from an enhanced power factor and markedly reduced lattice thermal conductivity, high average ZT and peak ZT are achieved in Ge- and In-codoped SnSe nanoplates. This work achieves an ultrahigh average ZT of 0.88 in polycrystalline SnSe by adopting nontoxic element doping, potentially expanding its usefulness for various thermoelectric generator applications.
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Nano Energy
·
2021
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IF 17.881
Haitao Li,Hui Yin,Han Dai,Hiang Kwee Lee,Yanying Cui,Fuwei Sun,Yihe Zhang,Qi An
Promoting the quality of surface-enhanced Raman spectra (SERS) holds immense significance in various research fields, such as high-sensitive detection or real-time in situ monitoring. However, obtaining rich molecular information from the vibration modes in SERS remains difficult due to the surface selection rules. Herein, we develop an electrically enhanced, composite SERS substrate by combining flower-like Ag nanostructures with a piezoelectric-dielectric polymeric film . The piezoelectricity generated in the polymeric film transforms into combined quasi-static electrical fields with multi-directional distributions and intensified plasmonic hotspots in the Ag nanoflowers . Molecules adsorbed on the Ag nanoflowers are propelled by the quasi-static electrical fields and deviate from the absorption equilibrium states, a key criterion to present additional SERS peaks. In addition, the intensified hotpots generate SERS peaks with higher intensities (> ~ 2 times). Dual-enhanced SERS in both the intensity and the number of vibration peaks e.g., 3 peaks more for 4-Mpy, are obtained from a variety of widely used molecular Raman probes as well as pesticide contaminants. The universality of the dual enhancement effects from our SERS design with increasing detection sensitivity demonstrates high applicability in the rapid and on-site detection of real samples. The changes to SERS spectra, and thus the molecular vibrational fingerprints, in the combined static and plasmonic electrical fields may also inspire scientific understanding in photoelectrical catalytic processes.
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Nature Communications
·
2022
·Vol. 13
·期 1
·1-10
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IF 17.694
Yang Yang,Zhu Xiaojuan,Wang Lili,Lang Junyu,Yao Guohua,Qin Tian,Ren Zhouhong,Chen Liwei,Liu Xi,Li Wei,Wan Ying
Pd catalysts are widely used in alkynol semi-hydrogenation. However, due to the existence of scaling relationships of adsorption energies between the key adsorbed species, the increase in conversion is frequently accompanied by side reactions, thereby reducing the selectivity to alkenols. We report that the simultaneous increase in alkenol selectivity and alkynol conversion is achieved by manipulating interstitial atoms including B, P, C, S and N in Pd catalysts. A negative linear relationship is observed between the activation entropies of 2-methyl-3-butyn-2-ol and 2-methyl-3-buten-2-ol which is highly related to the filling of d -orbital of Pd catalysts by the modification of p -block elements. A catalyst co-modified by B and C atoms has the maximum d charge of Pd that achieves a 17-fold increase in the turn-over frequency values compared to the Lindlar catalysts in the semi-hydrogenation of 2-methyl-3-butyn-2-ol. When the conversion is close to 100%, the selectivity can be as high as 95%.
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JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2024
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IF 4.1
Huanli Liu,Li Zhang
The pore structure of carbon-based materials and the voltage window of the electrolyte are two key factors affecting the energy density of carbon-based supercapacitors (SCs). In this paper, activated carbon materials of different pore sizes is successfully synthesized by chemical activation method by adjusting the mass ratio of ZnCl 2 to sucrose, and successfully applied to construct SCs based on different electrolyte systems. As the specific surface area of the prepared porous carbon materials shows a tendency to increase and then decrease, reaching a maximum in the presence of micropores. Further summarizing the constitutive relationship between pore structure-electrochemical performance in the high-concentration electrolyte system, it is found that the normalized specific capacity is larger at smaller pore sizes, and with the increase of mesoporous proportion, the normalized specific capacity decreases and tends to be stable. In addition, the different strengths of solvation of anions and cations in the electrolyte, with the cations contributing more to the contrast, and the presence of mesopores providing ion transport channels to improve the efficiency of ion transport in porous materials, which provide directions for designing a suitable pore structure for highly concentrated salt electrolytes, as well as another way of optimizing the properties of carbon-based materials for SCs.
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JOURNAL OF FISH DISEASES
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2024
·Vol. 47
·期 4
·e13915
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IF 2.2
Fei Yang,Bin Yang,Kaige Song,Yingjie Jin,Gaoxue Wang,Pengfei Li,Qing Yu,Fei Ling
Micropterus salmoides rhabdovirus (MSRV) is a formidable pathogen, presenting a grave menace to juvenile largemouth bass. This viral infection frequently leads to epidemic outbreaks, resulting in substantial economic losses within the aquaculture industry. Unfortunately, at present, there are no commercially available vaccines or pharmaceutical treatments to combat this threat. In order to address the urgent need for therapeutic strategy to resist MSRV infection, the antiviral activity of natural product honokiol against MSRV was explored in this study. Firstly, cellular morphology was directly observed in an inverted microscope when treated with honokiol after MSRV infection. The results clarified that honokiol significantly lessened cytopathic effect (CPE) induced by MSRV and protected the integrity of GCO cells. Furthermore, the viral nucleic acid expression (G gene) was detected by reverse transcription real-time quantitative PCR (RT-qPCR) and the results indicated that honokiol significantly decreased the viral loads of MSRV in a concentration-dependent manner, and honokiol showed a high antiviral activity with IC 50 of 2.92 μM. Besides, honokiol significantly decreased the viral titre and suppressed apoptosis caused by MSRV. Mechanistically, honokiol primarily inhibited the initial replication of MSRV and discharge of progeny virus to exert anti-MSRV activity. More importantly, in vivo experiments suggested that honokiol (40 mg/kg) expressed a fine antiviral activity against MSRV when administrated with intraperitoneal injection, which led to a notable 40% improvement in the survival rate among infected largemouth bass. In addition, it also resulted in significant reduction in the viral nucleic acid expression within liver, spleen and kidney at 2, 4 and 6 days following infection. What is more, 100 mg/kg honokiol with oral administration also showed certain antiviral efficacy in MSRV-infected largemouth bass via improving the survival rate by 10.0%, and decreasing significantly the viral nucleic acid expression in liver, spleen and kidney of largemouth bass on day 2. In summary, natural product honokiol is a good candidate to resist MSRV infection and has promising application prospects in aquaculture.
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PubMed
高影响因子
CERAMICS INTERNATIONAL
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2024
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IF 5.1
Yan Sun,Aowen Chen,Jingdao Yang,Kun Zhang,Sikai Wang,Xuerong Xu,Luyue Niu,Yue Jing,Ci Wang,Jing Ren,Jianzhong Zhang
Expanding gain bandwidth into the L-band for erbium-doped fiber amplifiers (EDFAs) is a crucial strategy to overcome limitations in prevalent C-band focused commercial silica-based EDFAs, significantly boosting optical network transmission capacity. Herein, we synthesized Er 3+ -doped broadband near-infrared emission tellurite glasses utilizing the melt quenching process, systematically exploring the impact of ZnCl 2 on the glass structure and optical properties. The 82TeO 2 –3Nb 2 O 5 –15ZnCl 2 –3Er 2 O 3 (TNZ15) glass emerged as a standout candidate for broadband amplifiers around wavelength at 1.55 μm. With escalating ZnCl 2 concentration, a discernible red shift in the emission peak wave lines was observed, accompanied by an expansion of the full width at half maximum (FWHM) from 98 nm to 106 nm. Noteworthy characteristics of all samples included exceptional thermal stability and elevated near-infrared (NIR) transmittance. Application of the Judd-Ofelt (J-O) theory facilitated the calculation of J-O parameter intensity, providing deeper insights into the optical behavior of the materials. Finally, the evaluation of TNZ15 planar optical waveguides, employing the vertical top pumping mode of two 980 nm LEDs, encompassed both the C-band (1530–1565 nm) and the L-band (1565–1625 nm). The results underscore the potential of TNZ15 glass as a promising gain material for broadband optical amplifiers and lasers, offering valuable insights into the development of next-generation optical amplification technologies.
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Toxicology Research
·
2024
·Vol. 13
·期 3
·
IF 2.2
Ma Peng,Wang Xu,Wen Xiuqi,Pu Lingyun,Ou Yu
IntroductionCurrently, the role and mechanism of dopamine in non-alcoholic steatohepatitis (NASH) remains unclear.MethodsIn vitro experiments utilized FFA and LPS to establish NASH cell models, while a fibrotic cell model was created using TGFβ1 to investigate the impact of dopamine on cellular lipid metabolism, inflammation, and fibrosis. In vivo experiments involved the use of MCD and HFD diets to induce NASH in mouse models for observing the effects of dopamine on NASH disease progression.ResultsOur study showed that dopamine significantly downregulated the expression levels of Caspase 1, IL-1β and IL18 in the HepG2 NASH cell model. In addition, dopamine could inhibit the TGF-β1-induced accumulation of collagen I and α-SMA in LX2 cells. In vivo experiments have shown that dopamine attenuation in mice is associated with MCD diet-induced and HFD-induced steatohepatitis. Mechanically, dopamine inhibits the p65 signaling pathway in NASH.ConclusionIn conclusion, the present study demonstrates the role of dopamine in ameliorating the symptoms of NASH and provides a direction for future research on the application of the dopaminergic system to liver disease.
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JOURNAL OF HAZARDOUS MATERIALS
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2024
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IF 12.2
Hongyi Shu,Chuang Wang,Liu Yang,Dongcang Sun,Changtong Song,Xianhong Zhang,Dong Chen,Yuhong Ma,Wantai Yang
Nowadays, effluent treatment is a severe challenge mainly because of its complex composition, which includes oil, heavy metal ions, and dyes. Developing new intelligent membranes is one of the strategies to tackle these significant challenges in wastewater treatment . In this study, we fabricated asymmetric polyethylene glycol terephthalate (PET) membranes by grafting cross-linked poly (itaconic anhydride) (CL-PITA) nanoparticles onto the irradiated face. These nanoparticles were then functionalized with polyethyleneimine (PEI) and protonated with HCl to introduce numerous active electropositive amine groups. The fundamental purpose was to increase surface roughness, introduce numerous hydrophilic groups, and modify it to create a multi-functional PET membrane to separate complex environments. The promising results demonstrated that the protonated PET- g -ITA/DVB (10) -cat membrane exhibited excellent separation efficiencies (SE) for water/light oil, water/heavy oil and oil-in-water (O/W) emulsion. Compared to PET- g -ITA/DVB (0) -cat, it showed superior performance in SE for O/W emulsion and flux decay for water/light oil after 10 cycles. More interestingly, owing to numerous positively charged active amino groups and negativley charged carboxylate groups, the intelligent membrane exhibited a high removal rate of ca. 90 % for anionic dye (congo red) and heavy metals (Cu 2+ and Co 2+ ), showing great potential in complex water treatment environments.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2025
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IF 4.6
Jingjiao Xie,Huiyuan Gong,Zhihan Du,Chen Hong,Wen Luo
Hydrogen sulfide (H 2 S) plays an important role in various pathophysiological processes, and its concentration is associated with various diseases. As such, the development of new H 2 S probes for the early detection of these diseases is of great significance. To date, a variety of probes have been developed for H 2 S detection, however, most probes exhibit response to other sulfur-containing compounds, resulting in a lack of specificity and weaker anti-interference performance. In this paper, a new flavone-based near-infrared (NIR) fluorophore was synthesized by introducing a 5-[4-(dimethylamino) phenyl] thiophene group at the 2-position of the chromone structure. Moreover, using nitrobenzoate as recognition group, two novel probes (TF-3NO 2 and TF-4NO 2 ) were synthesized to detection of H 2 S in biological systems. Among them, TF-3NO 2 exhibited a more specific fluorescent response to H 2 S compared to TF-4NO 2 . Upon treatment with H 2 S, the fluorescence intensity showed a significant increase, showcasing the high specificity, strong anti-interference capability, near-infrared emission (690 nm), and large Stokes shift (∆λ = 223 nm) of the probe. Moreover, the probe was successfully applied for imaging both exogenous and endogenous H 2 S in cells and mice, and enabled to distinguish changes in the H 2 S concentration in the brains of APP/PS1 transgenic and wild-type mice. The above results indicate that TF-3NO 2 can penetrate the mouse blood brain barrier, and is expected to be a powerful molecular tool for detecting H 2 S in living systems within basic and biomedical research fields.
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ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Luyang Zhang,Ziran Wang,Zaiyu Zhang,Yuting Huang,Zhongjing Ren,Haipeng Wang,Wu Duan,Chaqi Gai,Chen Wang,Yang Zhang,Bomi Gweon,Rui You,Peng Yan
Metabolic health is a major global health challenge associated with increased risks of disability, cancers, premature deaths, and a negative impact on patient quality of life. Precise monitoring of biomarkers in human urine, including metabolites and electrolytes, provides crucial guidance for treatment. While rich impurities in urine will induce cross-interference of the biosensors array, making continuous and reliable analysis of multiple biomarkers challenging. To address these issues, a multiplexed and in situ self-calibrated biosensing system (MSSCBS) is proposed with remarkably high stability and sensitivity in untreated urine samples. These desirable characteristics are achieved through the design of multiple electrochemical channels with self-assembled nanostructure and an in situ bio-signals self-calibration method of dynamic normalized least mean squares. MSSCBS delivers reliable sensitivities (e.g., 0.04 µA/µ m for uric acid), a wide linear range (e.g., 0.2–23.6 m m for glucose), and long-term stability (>20 days) of urinary impurities. Combination with a customized circuit for signal processing and wireless data transmission to mobiles supports convenient and long-term continuous monitoring of urine. This study validates MSSCBS's usability in assessing metabolic states in healthy participants and patients with diabetes, kidney disease, showing the potential of at-home biosensing platform for healthcare applications.
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