Journal of Cotton Research
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2024
·Vol. 7
·期 1
·1-14
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IF 3.1
Wang Wenhao,Song Xianpeng,Wang Dan,Ma Yajie,Shan Yongpan,Ren Xiangliang,Hu Hongyan,Wu Changcai,Yang Jun,Ma Yan
Background Plant hormones profoundly influence cotton growth, development, and responses to various stresses. Therefore, there is a pressing need for an efficient assay to quantify these hormones in cotton. In this groundbreaking study, we have established QuEChERS-HPLC‒MS/MS method, for the simultaneous detection of multiple plant hormones in cotton leaves, allowing the analysis and quantification of five key plant hormones. Results Sample extraction and purification employed 0.1% acetic acid in methanol and C18 for optimal recovery of plant hormones. The method applied to cotton demonstrated excellent linearity across a concentration range of 0.05–1 mg·L −1 , with linear regression coefficients exceeding 0.99. The limits of quantification (LOQs) were 20 μg·kg −1 for GA 3 and 5 μg·kg −1 for the other four plant hormones. Recovery rates for the five plant hormones matrix spiked at levels of 5, 10, 100, and 1000 μg·kg −1 were in the range of 79.07% to 98.97%, with intraday relative standard deviations (RSDs) ranging from 2.11% to 8.47%. The method was successfully employed to analyze and quantify the five analytes in cotton leaves treated with plant growth regulators. Conclusion The study demonstrates that the method is well-suited for the determination of five plant hormones in cotton. It exhibits excellent selectivity and sensitivity in detecting field samples, thus serving as a robust tool for in-depth research into cotton physiology.
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POLYMER BULLETIN
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2024
·
IF 3.1
Xiao Qinglin,Ai Xiujuan,Chen Zhiyuan,Chen Piaoyi,Chen Lingling,Liu Ou,Ma Yongyan,Huang Yugang,Li Xufeng,Ye Guodong
Transcatheter arterial embolization is one of the important tools in the interventional treatment of hepatocellular carcinoma. However, the existing embolic agents cannot achieve long-term visualization effectiveness. Therefore, we developed a radiopaque embolic microsphere (PTADE@Ta) capable of long-term imaging. PTADE@Ta was successfully prepared by dispersing tantalum nanoparticles in a poly (diallyl terephthalate) via photopolymerization. The microspheres were characterized by SEM observation and thermogravimetric analysis. The in vitro biocompatibility was assessed by determining the cell metabolic activity of human umbilical vein endothelial cells, and the in vivo biocompatibility was assessed by observing tissue sections from New Zealand white rabbits. Their non-degradability was verified by their degradability in lysozyme solution. The radiopaque effect was verified by X-ray and CT imaging capability. The results showed that the embolic product has good dispersibility, thermal stability, biocompatibility and long-term imaging. Graphical abstract
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CARDIOVASCULAR DRUGS AND THERAPY
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2024
·
IF 3.1
Ye Bozhi,Cai Xueli,Liang Xiaohe,Chen Yunxuan,Dai Shanshan,Huang Zhuqi,Huang Weijian,Zhang Lei,Wang Zixuan,Xing Jincheng,Lai Xianhui,Huang Zhouqing,Jia Zhuyin
Purpose Inflammatory responses induced by NLRP3 inflammasome contribute to the progression of atherosclerosis. This study seeks to investigate the effect of emodin on the NLRP3 inflammasome in atherogenesis and to probe the underlying mechanism. Methods ApoE-knockout (ApoE −/− ) mice were treated with a high-fat diet (HFD) for 12 weeks and intragastrically with emodin for 6 weeks. Human mononuclear cell line THP-1 was pretreated with emodin or signaling pathway inhibitors and induced into macrophages using phorbol 12-myristate 13-acetate (PMA) for 48 h. The NLRP3-mediated inflammatory response was studied both in vivo and in vitro. The level of the inflammation was detected by western blot, real-time PCR analysis, and ELISA. Results Emodin attenuated atherosclerotic lesions in HFD-treated ApoE −/− mice. Emodin dramatically decreased the expression of NLRP3, GSDMD, IL-1β, and IL-18 in HFD-treated ApoE −/− mice and PMA-induced macrophages. Moreover, emodin significantly hindered the activation of nuclear factor kappa-B (NF-κB) by inhibiting the formation of the TLR4/MyD88 complex in PMA-induced macrophages. Conclusion Our data demonstrate that emodin can inhibit the development of atherosclerotic plaques by alleviating NLRP3/GSDMD-induced inflammation through repressing the TLR4/MyD88/NF-κB signaling pathway in macrophages. This finding suggests that emodin can be a potential candidate for the treatment of atherosclerosis.
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Virology Journal
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2025
·Vol. 22
·期 1
·1-14
·
IF 3.8
Liu Xianglan,Hu Jiaming,Wu Jiarui,Tian Yiru,Wang Jinbo,Wu Chunyan,Chen Qingfeng,Krall Leonard,He Yanping,Lu Qun
Background Human norovirus (HNV) is the predominant pathogen causing outbreaks of acute gastroenteritis globally. Despite significant efforts to combat norovirus infections, there is currently no FDA approved vaccine or antiviral drug available. Consequently, the development of effective antiviral agents is of critical importance. Methods and results In this study, a series of 41 5-cyano-2-thiacetyl aromatic pyrimidinone compounds were designed and synthesized. A cell viability-based screening for anti-murine norovirus (MNV) compounds was conducted, revealing that compound 29 (hereafter used as Co-29) exhibited antiviral activity against MNV. Co-29 demonstrated effective inhibition of MNV CW3 RNA replication, exhibiting an EC 50 of 58.22 μM. An RdRp enzyme activity assay indicated that Co-29 directly inhibits RdRp activity to both MNV and HNV. Molecular docking studies suggested that Co-29 interacts with the palm region of RdRp via hydrogen bonding with specific residues, which are conserved in RdRps across MNV and HNV norovirus variants. Conclusions In conclusion, our study suggests that the newly synthesized Co-29 may serve as a potential antiviral candidate or lead compound for future studies.
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Communications Biology
·
2025
·Vol. 8
·期 1
·1-15
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IF 5.1
Fan Zhan,Xu Yilun,Lu Yafang,Li Xinlin,Xu Mengli,Liu Jinxin,Cai Zhenzhen,Liu Jiayang,Su Jingping,Wang Jialu,Luo Qingming,Zhang Zhihong,Liu Zheng
The excessive accumulation of neutrophils within the epidermis is a significant hallmark of cutaneous diseases; however, the mechanisms governing neutrophil transepidermal migration (NTEM) remain inadequately understood. In this study, we develop trichromatic-fluorescence-labeled chimeric mice by utilizing Cx3cr1 GFP/+ Lyz2 RFP/+ mice as bone marrow donors and Krt14 YFP/+ mice as recipients. This approach enables us to visualize the process of NTEM and the crosstalk between neutrophils and monocytes in a murine model of irritant contact dermatitis (ICD). Intravital imaging reveals a preferential transmigration of neutrophils through hair follicle (HF), where dermal neutrophils exhibit limited mobility and interact with dermal monocytes. Notably, 18 h following hapten exposure, dermal neutrophils continuously migrate toward HF regions and form clusters within 3 h. Importantly, MMP-9 is identified as essential for the NTEM process; the depletion of dermal monocytes results in a significant reduction of MMP-9 expression in the skin and inhibits the NTEM process in ICD. Mechanistically, dermal monocytes are found to be a crucial source of the cytokines TNF-α and CXCL2, which promote the upregulation of MMP-9 in neutrophils. Therefore, our results highlight HF regions as crucial gateways for dermal monocyte-modulated NTEM and provide visual insights into the crosstalk between neutrophils and monocytes in inflammatory skin disorders.
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RARE METALS
·
2025
·
IF 11
Mao Pu,Sun Jie,Feng Hui-Min,Liu Zhi-Yong,Guo Kun,Xie Bing,Wang Ting,He Li-Qiang,Gao Jing-Hui
Copper calcium titanate (CaCu 3 Ti 4 O 12 , CCTO) ceramics with colossal permittivity have gained widespread concern because of their potential application in modern electronic devices with miniaturization and integration. However, the extent of grain and grain boundary contribution to the colossal permittivity of CCTO-based ceramics based on the internal barrier layer capacitor (IBLC) model is still in debate. This affects their electrical performance optimization and real-world applications. In this study, a series of novel lead-free colossal permittivity ceramics, x LiCuNb 3 O 9 –(1– x )CaCu 3 Ti 4 O 12 (LCNO-CCTO), were designed and prepared using a solid-phase reaction approach. The colossal permittivity response mechanism of LCNO-CCTO ceramics was further explored by performing the complex impedance spectrum and analyzing the activation energy from the grain and grain boundary contribution viewpoint. As a result, the LCNO-CCTO ceramics present the cubic perovskite structure with the space groups of \(Im \overline{3}\) . All the LCNO-CCTO ceramics exhibit the significantly enhanced colossal permittivity (10 5 ) response, and the ceramic with x = 0.15 shows the highest permittivity of about 4.64 × 10 5 (20 Hz, room temperature) accompanied by a lower grain resistance of 9.61 Ω and larger grain activation energy of 0.21 eV. The enhanced colossal permittivity response is primarily attributed to the great electrical response inside grains of LCNO-CCTO ceramics, resulting from a smaller grain resistance. Also importantly, the high-frequency dielectric relaxation characteristics are improved by incorporating the LCNO into CCTO ceramics as an ion form. Accordingly, the LCNO-CCTO ceramics show a suppressed high-frequency dielectric loss. These results can provide a thorough knowledge and useful optimization strategy for developing high-performance colossal permittivity materials. Graphical
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CATALYSIS LETTERS
·
2025
·Vol. 155
·期 5
·1-15
·
IF 2.4
Liu Tao,Zhou Guangming,Yu Bingyan,Fu Lihu,Yu Simiao,Xu Zhenjie,Lu Gang
To address the problem of dye wastewater pollution, hierarchical porous alumina ceramics (HPAC) were prepared as carriers in this study by using digital light processing (DLP) 3D printing combined with the freeze-drying method. The results showed that the hierarchical porous alumina ceramics with a porogenic agent content of 33 wt% exhibited the highest porosity of 34.20% ± 1.22% and a pore size of 2–5 nm. An efficient photocatalytic system was constructed by loading nickel oxide nanoparticles (n-NiO) via the sol-gel method. The prepared photocatalytic carriers and photocatalysts were characterized for structural and morphological analysis using X-ray diffraction (XRD), scanning electron microscopy (SEM), Brunauer-Emmett-Teller (BET) surface area analyzer, and energy-dispersive X-ray fluorescence spectroscopy (EDS). The results indicated that n-NiO/HPAC with 15.43% NiO loading achieved optimal performance in methylene blue (MB) degradation experiments, with the MB degradation rate reaching 94.51%. This study provides a theoretical basis and technical support for the practical application of porous-material-loaded n-NiO photocatalysts in dye wastewater treatment. Graphical abstract
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-11
·
IF 15.7
Zhi Yinglin,Shao Yan,Xia Rui,Lin Weikun,Cai Daohang,Zhao Fuxing,Dong Jiufeng,Li Qingxian,Wang Zihao,Li Lixuan,Gu Long,Tian Peng,He Zhen,Wang Jinlong,Ning Guiling,Li Baowen,Yang Canhui,Wang Hong,Yu Shuhong,Yu Yanhao
Oxide/elastomer composites combine the functional attributes of metal oxides with the mechanical deformability of elastomers, but face the challenge of balancing oxide loading and stretchability as ceramic fillers decrease the entropic elasticity of polymer networks. Here, we report an interfacial composite design that enables high oxide fraction and large stretchability by minimizing the contact area yet maximizing the binding strength between the oxide and elastomer. The elongation at break for an interfacial composite with 80 vol% of oxides reaches 500%, whereas that of a regular bulk composite with the same oxide fraction is 20%. These composites are synthesized based on a Marangoni co-assembly process with tuned interfacial tension and reaction at the water-oil interface. The assembly chemistry is nearly independent of oxides’ sizes, compositions, geometries, and functions, making this interfacial structure broadly applicable to optical, electric, magnetic, and thermal-conducting oxides. Compared to bulk composites, the interfacial composites deliver larger magnetic actuation, lower thermal resistance, and higher conformability with nonplanar surfaces, providing rich implications for designing intelligent and electronic systems.
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CELLULOSE
·
2024
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IF 4.9
Zhao Junchai,Chen Long,Zhou Wentao,Zhao Pengbo,Peng Zheng,Lin Xiaobo,Yang Jinhui
Here, a facile method to extract the carboxylated cellulose nanocrystals (CNCs) with high yield from microcrystalline cellulose (MCC) at room temperature (RT) is put forward that uses a solvent system of zinc chloride (ZnCl 2 ) and citric acid (CA) aqueous solution. The rod-like carboxylated CNCs were achieved with a maximum yield of 72.3% and a maximum carboxyl group content of 0.75 mmol/g. Meanwhile, the crystal transformation from cellulose I to II was detected with variation of solvent composition. In addition, to the best of our knowledge, this is the first time that the iridescent phenomenon was observed in extremely thin films which were prepared from carboxylated CNC suspension with a concentration of only 0.08–0.15 wt% via evaporation-induced self-assembly. The possible formation mechanism is considered to be related to the synergistic effects of film confinement and drying stresses. Furthermore, the interaction between Petri dish substrate and the film played a role. As the first example of isolation of carboxylated CNCs with high yield at RT using ZnCl 2 /CA aqueous solution, this work provides a facile and practical strategy for the preparation of functional cellulose nanomaterials.
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EUROPEAN JOURNAL OF PLANT PATHOLOGY
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2025
·
IF 1.9
Huang Zhixing,He Zhenrui,Ding Jiexin,Zhu Yiming,Zhou Erxun
Soybean root rot, caused by Fusarium neocosmosporiellum , poses a significant threat to soybean productivity. Although chemical fungicides are widely used, their environmental risk necessitate sustainable alternatives. This study proposes an integrated control strategy combining the biocontrol bacterium Pseudomonas aeruginosa E1 - 23 with prochloraz. Initial screening of seven candidate bacterial strains identified E1 - 23 as the most potent antagonist, exhibiting 64.1% inhibition against F. neocosmosporiellum in dual-culture assays. Concurrent fungicide evaluation revealed prochloraz as the optimal agent (EC 50 = 0.1646 μg/mL). Compatibility analysis demonstrated E1 - 23's robust tolerance to prochloraz concentrations at ≤ 50 μg/mL. In vitro combination of prochloraz (0.25 μg/mL) and E1 - 23 (1 × 10 6 CFU/mL) achieved 91.86% pathogen suppression, surpassing individual treatments by > 10% and theoretical additive effects. Greenhouse trials confirmed enhanced efficacy, with integrated application increasing disease control efficacy by 34.35%—significantly outperforming standalone bacterial (18.96%) or fungicide (20.52%) controls. The qRT-PCR analysis revealed that the combination application of E1 - 23 and prochloraz up-regulated the expression of some defense genes of soybean plants 5 days post-inoculation (dpi), but the induced plant disease resistance was low. This study highlights the potential of E1 - 23-prochloraz as an eco-friendly approach to mitigate soybean root rot while reducing fungicide dependency.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2025
·Vol. 36
·期 12
·1-21
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IF 2.8
Chen Yu,Yi Changnan,Wu Yurong,Yang Fan,Xu Longshan,Hu Yanling,Wang Xiaoshuai,Chen Yuanyi,Qiu Wenqian
Nanosheets self-assembled WO 3 microsphere with hollow and special core–shell structures was successfully synthesized using hydrothermal, acid etching, and heat treatment methods. The special core–shell WO 3 samples with oxygen vacancies (WN-O) have higher carrier concentration and specific capacitance. The symmetrical supercapacitors (SCs) assembled by WN-O show excellent potential in PVA/KOH gel electrolyte and 3 M KOH aqueous solution. The aqueous symmetric WN-O SCs demonstrated great capacitance (22 mAh g −1 , 1 A g −1 ), extraordinary stability in cycling (118% of the retained capacity after 20 000 cycles, 5 A g −1 ), and a huge energy storage capacity (8.8 Wh Kg −1 of energy density, 400 W Kg −1 of power density). Additionally, the all solid-state symmetric WN-O SCs displayed 52.2% retained capacitance even when the current density increases five times, to 5 A g −1 , and an outstanding capacity of 18.7 mAh g −1 at 1 A g −1 . The distinct core–shell structure and plenty of oxygen vacancies of the WN-O electrode are responsible for its exceptional electrochemical performance. The oxygen vacancies and loose core–shell structure provide more active sites, while the unique cavity structure on the core–shell provides channels for charge transfer and successfully prevents collapse caused by contraction and expansion during charge and discharge processes. The mechanism discovered in this study will contribute to the design of better performing WO 3 energy storage devices in the future.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2025
·Vol. 36
·期 25
·1-13
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IF 2.8
Zhang Yuexing,Feng Wenlin,Ullah Arif
To address the need for high-sensitivity carbon monoxide (CO) gas sensing at room temperature, a CO gas sensor based on Au-modified tin oxide/zinc oxide (SnO₂/ZnO) nanocomposites is fabricated. SnO₂ nanoparticles, ZnO nanosheets, and Au nanoparticles (AuNPs) were synthesized using sacrificial template, hydrothermal, and chemical reduction methods, respectively. The resulting nanocomposite was then drop-casted onto interdigitated electrodes and dried to obtain the CO gas sensor. The performance of the sensor was evaluated using a custom airtight chamber and a semiconductor parameter analyzer. The n–n heterojunction between SnO₂ and ZnO significantly increased oxygen vacancy in the composite material, enhancing surface chemisorption of oxygen. Moreover, the catalytic sensitization effect of AuNPs facilitated electron migration, while their inherent spillover effect promoted the activation of gas molecule interactions. Consequently, the sensor exhibited a high response (22.11%) to 70 ppm CO at room temperature, along with excellent stability, selectivity, and anti-interference capabilities. This work offers a promising approach for developing highly sensitive room-temperature gas sensors.
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