INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Xiaojun Wang,Binbin Liu,Zhili Liu,Jing Li,Runhua Lu,Haixiang Gao,Canping Pan,Wenfeng Zhou
The main goal of this study is to create a CS-CMC-SF aerogel consisting of chitosan sodium carboxymethylcellulose and silk fibroin. The aerogel is designed to remove types of dyes from water while also being environmentally friendly. This innovative adsorbent has been optimized for extracting both cationic and anionic dyes from solutions. It incorporates chitosan sodium carboxymethylcellulose and silk filament fibers to enhance its strength . Experimental data illustrates that the CS-CMC-SF aerogel possesses remarkable adsorption capabilities - 5461.77 mg/g for Congo Red (CR), 2392.83 mg/g for Malachite Green (MG), and 1262.20 mg/g for Crystal Violet (CV). A kinetic study aligns with the pseudo-second-order kinetic model suggesting predominant chemisorption phenomena occur during adsorption process. Isotherm analysis further identifies multilayered adsorption occurring on irregularly shaped surfaces of the aerogel while thermodynamic assessments validate exothermic and spontaneous characteristics inherent in its absorption mechanism. Several analytical methods such as SEM, FT-IR, XRD, and XPS were employed to examine physicochemical attributes tied to this unique material design conceptually; identifying mechanisms including pore filling, π-π interactions, ion exchange activity, electrostatic connections along with hydrogen bonding inducing overall superior performance output. Furthermore substantial soil biodegradability alongside compostable features associated with our proposed CS-CMC-SF aerogels established it's potential suitability within applications demanding sustainable options thereby validating its underlying ecological credibility.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Mochou Gao,Chenglin Xu,Jinyu Deng,Tong Zhu,Zhilong Xie,Xueyan Zou,Wensheng Yang
Chitosan (CS) was deposited onto the surface of Fe 3 O 4 nanoparticles by anionic cross-linking to obtain Fe 3 O 4 @CS nanocomposite with improved biocompatibility ascribed to CS. The optimized reaction condition for preparing Fe 3 O 4 @CS was established. Furthermore, polyacrylic acid (PAA) was grafted onto the surface of Fe 3 O 4 @CS to obtain magnetically responsive Fe 3 O 4 @CS/PAA nanocomposite; and dextrin was grafted onto the surface of Fe 3 O 4 @CS/PAA by hydrogen bonding to obtain Fe 3 O 4 @CS/dextrin nanoadsorbent with desired magnetic response for the rapid purification of the maltose binding protein-tagged (MBP-tagged) fusion proteins from Escherichia coli lysate. The as-obtained Fe 3 O 4 @CS/PAA nanocomposite was loaded with relevant antibodies to construct the platform for the purification of MBP-tagged, glutathione S-transferase-tagged, and histidine-tagged fusion proteins. Findings demonstrate that multi-tagged proteins platform exhibits rapid recognition and high binding abilities as well as desired specification, universality, and recycling ability to the tested tagged fusion proteins, because they can strongly load different protein ligands.
✓ 已验证
产品关联
DOI
高影响因子
ChemSusChem
·
2024
·
IF 7.5
Lixinyu Wang,Shangwen Zha,Shenxiang Zhang,Jian Jin
Graphical A highly stable, CO 2 facilated transport membrane that can operate at simulated flue gas conditions with temperature up to 90 °C and high humidity is reported. The mobile amine-carriers for CO 2 were stablized within the sulfonated chitosan ion gel membrane. By virtue of carrier-facilitated transport, high CO 2 permeance (as high as 1155 GPU) and ultrahigh CO 2 /N 2 selectivity (above 550) were achieved. Capturing carbon dioxide (CO 2 ) from flue gases is a crucial step towards reducing CO 2 emissions. Among the various carbon capture methods, facilitated transport membranes (FTMs) have emerged as a promising technology for CO 2 capture owing to their high efficiency and low energy consumption in separating CO 2 . However, FTMs still face the challenge of losing mobile carriers due to weak interaction between the carriers and membrane matrix. Herein, we report a sulfonated chitosan (SCS) gel membrane with confined amine carriers for effective CO 2 capture. In this structure, diethylenetriamine (DETA) as a CO 2 -mobile carrier is confined within the SCS gel membrane via electrostatic forces, which can react reversibly with CO 2 and thus greatly facilitate its transport. The SCS ion gel membrane allows for the fast diffusion of amine carriers within it while blocking the diffusion of nonreactive gases, like N 2 . Thus, the prepared membrane exhibits exceptional CO 2 separation capabilities when tested under simulated flue gas conditions with CO 2 permeance of 1155 GPU and an ultra-high CO 2 /N 2 selectivity of above 550. Moreover, the membrane retains a stable separation performance during the 170 h continuous test. The excellent CO 2 separation performance demonstrates the high potential of gel membranes for CO 2 capture from flue gas.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Water Process Engineering
·
2025
·
IF 6.7
Hanlu Zeng,Yunlan Xu,Dengjie Zhong,Qingmei Qiao,Yuqin Yang,Jitai Li
Photocatalytic fuel cell (PFC) is a new device that can efficiently degrade organic pollutants and recover their energy. This paper used solvothermal method to prepare a flower-like copper bismuth oxide/bismuth oxy bromide/Chitosan/Titanium (CuBi 2 O 4 /BiOBr/CS/Ti) photoanode. It was then assembled with a Cu cathode to produce a PFC for reducing rhodamine B (RhB) and generating power. Different analytical methods were utilized to analyze the photoanode's chemical composition, crystal structure, and electrochemical properties. CuBi 2 O 4 /BiOBr/CS/Ti had higher photocatalytic activity than single and binary composite photoanodes, which had good stability. The RhB degradation rate, maximum power density ( P max ), maximum photocurrent density ( J sc ) and the fill factor ( FF ) of the PFC were 90.98 %, 30.80 μW·cm −2 , 0.283 mA·cm −2 and 0.22, respectively. The results of transient photocurrent (i-t), electrochemical impedance spectra (EIS) and Mott-Schottky (M-S) spectra, and free-radical capture experiments indicated that the enhancement of the photocatalytic performance of the CuBi 2 O 4 /BiOBr/CS/Ti photoanode was due to the formation of the Z -scheme heterojunction between CuBi 2 O 4 and BiOBr and the electron mobility of CS. This achieved the rapid separation and transfer of electron (e − )-hole (h + ) pairs and maintained the strong oxidation of holes in the valence band (VB) of BiOBr and the strong reduction of electrons in the conduction band (CB) of CuBi 2 O 4 . This research introduces a novel approach to design and establish excellent performance photoanode of PFC system.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Jiali Yang,Yuanyuan Han,Lifeng Zhang,Qiteng Ding,Shuwen Sun,Shuai Zhang,Yue Wang,Ning Wang,Hewei Wei,Taojing Yu,Wencong Liu,Chuanbo Ding
Bone defects have always been a difficult problem in clinical practice. Taxifolin (TAX) is beneficial to bone regeneration. In order to obtain more attractive biomaterials, we extracted cellulose (LC) from larch sawdust and prepared a TAX-loaded hydrogel (DCT) together with L-arginine chitosan (CA). The hydrogel had a uniform porous structure and good mechanical properties. After drug loading, the adhesion, antibacterial, and antioxidant properties of the hydrogel were improved. In addition, DCT has good biocompatibility. In vitro cell experiment results showed that DCT can promote cell proliferation and migration, and DCT has a certain ability to promote the osteogenic activity and enhance the expression of osteoblastic factors (OCN and Osx) and vascular endothelial growth factor (VEGF) in MC3T3-E1 cells. In addition, in vivo studies showed that the DCT treatment could promote bone regeneration by increasing the levels of osteogenic markers (OPN, OCN, and Osx) and VEGF. Transcriptome analysis showed that DCT intervention affected the hematopoiesis function in bone tissue. Meanwhile, KEGG analysis showed that DCT promoted bone regeneration mainly by activating the PI3K/AKT signaling pathway, which was verified by a western blot. Therefore, DCT is a good material for bone repair.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
POLYMERS FOR ADVANCED TECHNOLOGIES
·
2025
·Vol. 36
·期 3
·e70140
·
IF 3.4
Xianning Wang,Runqi Zhang,Lujia Xuan,Mengmeng Yu,Jianqing Mao,Gang Cheng,Jieqiong Yan,Hongzhen Wang
Covalent adaptable networks offer a viable approach for producing recyclable rubber materials. Nevertheless, the intricate synthesis process and insufficient mechanical strength limit their commercialization applications. In this study, the reinforced, thermal-healing, and recyclable chitosan/ethylene propylene diene rubber (CEF-CS) was synthesized using a solid-phase blending process via the Diels-Alder (D-A) reaction. Furfural modified chitosan (F-CS) was included as a reinforcing filler and dynamic cross-linking point into the network formed via the D-A reaction. The influence of F-CS content on the mechanical, thermomechanical, and thermal repair characteristics of CEF-CS composites was examined. The results showed that the CEF-CS composites exhibited certain mechanical strength and dependable repair capabilities. As the F-CS content increased, the tensile strength of CEF-CS composites initially rose and subsequently declined, reaching a peak of 5.1 MPa, which was 5.1 times more than the control without F-CS. The first healing efficiency of tensile strength exceeded 70%, whereas the second healing efficiency was above 60%. Moreover, the simple preparation procedure and enhanced mechanical strength facilitate the commercial utilization of recyclable rubber materials, which is crucial for addressing the environmental pollution issue associated with rubber materials.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Aili Niyazi,Chaoqun Mu,Ting Wang,Wangsheng Ye,Lvling Zhong,Zhixian He,Haoyang Xu,Zhiqiang Zhang,Liang Zhang
In this work, temperature-responsive poly(N-isopropylacrylamide) (PNIPAM) and the guanylthiourea (GLA) were used to modify chitosan (CS) to prepare a novel PNIPAM/GLA/CS adsorbent for Ag(I) ions. Temperature variations near the lower critical solution temperature (LCST) facilitate the adjustment of functional group distribution within the composite material, thereby influencing its adsorption performance for silver ions. The characteristics of this composite material were confirmed using a variety of techniques, including scanning electron microscopy (SEM), variable-temperature ultraviolet-visible near-infrared spectroscopy, Fourier-transform infrared spectroscopy (FTIR), Raman spectroscopy, X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS). Studies on the adsorption of Ag(I) ions by the PNIPAM/GLA/CS adsorbent indicated that the optimal pH for adsorption is 6.0. The adsorption kinetics were best described by the pseudo-second order kinetic model, while the equilibrium adsorption data aligned more closely with the Langmuir adsorption isotherm model, achieving a maximum adsorption capacity of 336.33 mg/g at 40°C. Experimental results demonstrated that higher adsorption amounts were observed above the LCST, while desorption of target ions was more favorable below the LCST. This research provides valuable insights for the design of new structural adsorbents.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
EUROPEAN POLYMER JOURNAL
·
2025
·
IF 6.3
Yanfei Liu,Juan Li,Shengnan Huang,Xiaokai Wu,Shaowen Huang,Dingbo Shu,Chi Zhang,Xiaogang Yin
In this study, a novel three-dimensional bio-based superabsorbent hydrogel, SL-P(AA-AMPS)/CMCS, was synthesized via freeze-drying using sodium lignosulfonate (SL) with rigid phenylpropane structures as the bio-based framework, carboxymethyl chitosan (CMCS) enriched with hydrophilic groups (–OH, –COOH, and –NH 2 ) as the hydrophilic modifier, and acrylic acid (AA) and 2-acrylamido-2-methylpropanesulfonic acid (AMPS) as monomers. Polymerization was initiated by ammonium persulfate (AP) and crosslinked with N,N’-methylenebisacrylamide (MB). The hydrogel’s structure, morphology, and absorption properties were systematically characterized using Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and scanning electron microscopy (SEM). Results revealed a uniform porous structure with an average pore size of 5.8 μm. Absorption capacities in deionized water and 0.9 % NaCl solution reached 1132.9 g/g and 127.9 g/g, respectively, surpassing commercial diaper fillers (273.3 g/g and 61.5 g/g) and feminine hygiene products (223.5 g/g and 45.8 g/g). Under pressurized conditions (2068 Pa), absorption values remained high at 125.7 g/g (deionized water) and 24.0 g/g (0.9 % NaCl solution). The hydrogel exhibited exceptional water retention, retaining 88.8 % and 85.8 % of absorbed water after 8 h at 40 °C and 60 °C, respectively. Swelling kinetics followed a pseudo-first-order model (R 2 > 0.99), achieving equilibrium within 600 s (deionized water) and 60 s (0.9 % NaCl solution). Biodegradation tests demonstrated a 47.5 % degradation rate in soil after 28 days, significantly exceeding that of non-bio-based P(AA-AMPS) (3.7 %). Application tests highlighted superior absorption capacities for artificial urine (82.4 g/g) and blood (179.2 g/g), outperforming conventional hydrogels by 3.3- and 7-fold, respectively.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
·
2025
·
IF 3.5
Donghui Li,Ziyuan Zhou,Shilin Liu,Yan Li
BACKGROUND Cinnamaldehyde (CA) is the main functional component of cinnamon essential oil, exhibits strong anti-microbial activity and safety. Shellac (SHL) nanoparticles enable the encapsulation and controlled release of CA while improving the physiochemical properties of chitosan (CS) films. To strengthen the anti-bacterial activity of SHL–CS films, CA–SHL nanoparticles were prepared by an anti-solvent precipitation method with Tween 80 as surfactant, and subsequently incorporated into CS film-forming solution. The resulting CA–SHL nanoparticle-filled CS coatings were then applied for the preservation of chilled beef. RESULTS The particle size of CA–SHL nanoparticles showed a unimodal distribution, decreasing with higher SHL content or lower CA concentration. Stable CA–SHL nanoparticles had relatively low zeta-potential values, indicating the stabilization effect of Tween 80. Incorporation of CA–SHL nanoparticles into CS films improved UV barrier properties, reduced water vapor permeability, improved pH corrosion resistance, and strengthened anti-bacterial activity. The CA–SHL nanoparticle-filled CS coatings extended the shelf life of chilled beef from 4 to 8 days. CONCLUSION The enhanced properties of CA–SHL nanoparticle-filled CS composite films highlight their strong potential for food packaging and preservation. © 2025 Society of Chemical Industry.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2025
·
IF 5.4
Hongdong Song,Yaqiong Chen,Ruihan Huang,Xiao Guan
To enhance the oral bioavailability and hypoglycemic effect of insulin, we developed a novel bilayer liposome delivery system in this study. The outer layer of this system was decorated with propanoic acid-functionalized chitosan (CS/PA) to improve gastrointestinal stability and facilitate intestinal targeting of mono-carboxylate transporter protein 1 (MCT1). We encapsulated insulin in this newly developed delivery system. The CS/PA coating significantly enhanced the protective effect of liposomes on insulin in the gastrointestinal environment. Experiments using Caco-2 cells and ligated intestinal loops showed that IN-LIP-CS/PA facilitated insulin absorption and increased intestinal permeability. Importantly, MCT1-mediated energy-dependent endocytosis played a crucial role in the absorption process. Additionally, endocytosis of IN-LIP-CS/PA was mediated through clathrin, lipid raft, caveolin, and macropinocytosis. Furthermore, the endoplasmic reticulum and Golgi apparatus were mainly involved in the intracellular transport of IN-LIP-CS/PA. The combination of MCT1-mediated endocytosis and the intracellular transport pathways may help IN-LIP-CS/PA avoid lysosomal degradation, thereby improving the intracellular transport efficiency of insulin. In vivo studies demonstrated that IN-LIP-CS/PA achieved a significantly better hypoglycemic effect. These findings suggested that the newly developed bilayer liposome delivery system holds promise as an effective platform for the oral delivery of insulin.
✓ 已验证
产品关联
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2025
·
IF 12.5
Lu Qin,Zhixiang Cui,Ziwei Zhang,Qiyao Zhai,Yu Wu,Jian Guan,Enyu Xu,Xin Zhang,Shirui Mao
Inspired by the structural and functional attributes of Cell-penetrating peptides (CPPs), in this study, diverse cationic and hydrophobic amino acids (AAs), which are regarded as the essential sequence of CPPs, were adopted to functionally modify chitosan (CS) to further enhance drug absorption across lung epithelial cells, and explore the absorption enhancing mechanism of different AA categories. Here, taking octreotide as a drug model, multifarious amino acids decorated chitosan copolymers (AA-CSs) were synthesized to investigate the influence of biomimetic AA-CSs structure on drug transmembrane absorption utilizing both 3D Transwell cell models and Sprague Dawley rats. It was demonstrated that indeed the absorption enhancing action of AA-CSs was AA categories-dependent. In comparison to native CS, hydrophobic AA-CSs induced no obvious enhancement in transmembrane permeation, while cationic AA-CSs improved drug absorption across pulmonary epithelium to varying degrees, with the highest enhancement ratio observed for arginine-CS (Arg-CS) group. Mechanism studies indicated paracellular pathway-mediated drug transport of AA-CSs. The in vivo pharmacokinetic data from microparticle groups revealed the AA categories-dependent absorption enhancing effect. In conclusion, the absorption enhancing activity of AA-CS copolymers depends on their AA categories, the enhancement extent of cationic AAs, particularly arginine, is preferable than that of hydrophobic AAs.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2025
·
IF 6.6
Tangyu Yang,Haiwei Jia,Yuting Song,Shiqi He,Bing Li,Lin Li,Xia Zhang
Sucrose fatty acid esters are increasingly valued as multifunctional surfactants, nutraceuticals, and bacteriostats due to their emulsifying and antimicrobial properties. While enzymatic synthesis provides an eco-friendly route to high-purity esters, challenges remain in optimizing lipase activity, reusability, and mass transfer. This study introduces a novel edible biomaterials-based catalytic system: lipase immobilized within shellac nanoparticle-coated chitosan microgels (SCL) for synthesizing sucrose laurate via Pickering interfacial catalysis (PIC). SCL stabilized oil-in-water (O/W) emulsions, with sucrose and vinyl laurate partitioned into aqueous and oil phases, respectively. Structural characterization (SEM, CLSM, Cryo-SEM) revealed SCL's localization at the O/W interface, with preferential oil-phase immersion and ordered interfacial alignment. Optimized conditions yielded a conversion rate of 55.35 ± 1.88 %, and the immobilized lipase retained >80 % activity over four cycles. Purified via solvent extraction and chromatography, the product was confirmed as 6-sucrose monolaurate (through FT-IR, NMR, XRD, and TG-DSC). Comparative analysis demonstrated its higher air/water interfacial stabilization versus commercial sucrose monoesters, evidenced by lower critical micelle concentration ( cmc ), enhanced emulsifying/foaming capacity, and improved pH/thermal stability. Collectively, this SCL-based PIC system achieved sustainable synthesis of 6-sucrose monolaurate with exceptional enzyme recyclability, overcoming limitations in lipase stability and mass transfer, and produced a surfactant with superior properties.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）