SENSORS AND ACTUATORS B-CHEMICAL
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2024
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IF 8
Guopan Sun,Shanfu Sun,Yinglin Wang,Xidong Hao,Yue Hao,Chao Liu,Caili Gong,Qianyong Yang,Weian Du,Pengfei Cheng
Developing efficient drug-detecting technologies is critical to the fight against their related abuse and trafficking crimes. In the present work, a novel morphine detection device based on metal-oxide-semiconductor (MOS) gas sensors with low-cost, highly sensitive, and portable is designed and fabricated. The exclusive sensitive material, ZnO nanoparticles self-assembly porous networks (ZnO-N) with ample oxygen vacancies (O V ) defects prepared by PVP-chelated precipitation followed by a chemical blowing calcination method, is decisive to morphine drug identification. O V defects can modulate the intrinsic electronic structure and endow ZnO-N with more suitable band structures for enhancing oxygen species adsorption and morphine molecules oxidation. The optimal ZnO-N-2 sensor exhibits positive linear relationship response values of 1.1–8.8 in the concentrations of 2–200 ppm toward the standard morphine drug sample at the optimal operating temperature of 250°C. More importantly, the homemade portable device equipped with the ZnO-N-2 sensor can accurately identify the morphine drug and perform early warning. This work innovatively demonstrates the feasibility of MOS gas sensors for the detection of stashing morphine drugs in methanol, which is of great significance for effectively combating global drug-related crimes.
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JOURNAL OF CHROMATOGRAPHY A
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2009
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IF 3.756
Jia Li,Huan-Yang Qi,Yan-Ping Shi
News stories about the contamination of milk with melamine in China emerged on Sept 11, 2008, and the situation has since become an international health scare. In this work, a novel analytical method based on enrichment and pretreatment of analytes in the milk sample, hollow fiber sorptive extraction and gas chromatography–mass spectrometry has been developed for the rapid analysis of melamine in the dairy products. In the proposed method, melamine in the fresh milk was extracted by zirconia hollow fiber, enriching on zirconia coating of the hollow fiber, and then analyzed by GC–MS. The method validations including linearity, limit of detection, limit of qualification, recoveries at three different concentrations, precision, and repeatability were investigated. It was found that the proposed method provided linear range from 0.001 to 1000 μg/mL ( r 2 = 0.9997), low detection limit of 0.001 μg/mL, and preferable recoveries at three different concentrations. The obtained results demonstrated that zirconia hollow fiber combined with GC–MS is a simple, rapid and solvent-free method for the analysis of melamine in the dairy products.
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MATERIALS RESEARCH BULLETIN
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2024
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IF 5.3
Yu Chang,Jianan Zhang,Ivan S. Babichuk,Hailong Liu,Yijie Liu,Jian Yang
The release of ammonia (NH 3 ) in industry or daily life is harmful to human health. A gas sensor was developed using h -MoO 3 nanorods and graphene film to detect and eliminate this. The h -MoO 3 nanorods were first synthesized by chemical bath deposition using ammonium molybdate tetrahydrate (NH 4 ) 6 Mo 7 O 24 •4H 2 O and HNO 3 and then deposited on the graphene film transferred to SiO 2 /Si substrate by electrochemical bubbling method. Subsequently, gas-sensitive h -MoO 3 @Graphene composite films were prepared and analyzed using Raman, XRD, SEM, and UV–vis. The gas sensor's performance was evaluated to detect NH 3 at a room temperature concentration range of 1–60 ppm. Compared with graphene, the conductivity of the composite film with 10 mg/ml h -MoO 3 nanorods was increased by 40 % and the sensitivity increased by 10 times. The sensor h -MoO 3 @G-10 showed the best sensing performance to 1 ppm NH 3 . Sensor sensitivity, response and recovery time are 1.1 %, 46.8 s and 17.8 s.
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Journal of Materials Research and Technology-JMR&T
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2024
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IF 6.2
Jinan Cao,Jingping Wang,Youlong Xu,Hao Yuan,Lihua Yang,Huiying Yuan
The oil and gas industry frequently uses liquid corrosion inhibitors to reduce equipment and pipeline corrosion. However, this approach requires frequent additions, which are costly in terms of labor and materials. Solid corrosion inhibitor capsules (SCICs) have become an optimal alternative, as they provide long-term corrosion protection. However, the current encapsulation materials need to be modified for improving encapsulation capability. In this study, lauryl acrylate (LA) was grafted onto Ethylene-vinyl-acetates (EVA) to reduce its crystallinity and increase the interface force between EVA and oleic imidazoline (OIM). OIM was then encapsulated using the grafted EVA (EVA- g -LA) to form matrix-type solid capsules that possess the high encapsulation efficiency and long service life. The analysis with a UV–Vis spectrophotometer revealed that OIM had a stable release process from the SCIC matrix. Over a period of 91 days, the released OIM still had a high corrosion inhibition efficiency towards N80 steel (>80%). Using the prepared SCIC can reduce annual anticorrosion costs in oil and gas fields by 70%.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2024
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IF 9.4
Le Guo,Yi Zhou,Jiayi Ding,Jiabao Xiong,Lijun Zhu,Siyiti Amuti,Chi Zhang,Zhong Du,Xueliang Zhang,Biao Dong,Nuernisha Alifu
The integration of photothermal and near-infrared (NIR) imaging capabilities of indocyanine green (ICG) small molecules has attracted considerable attention in tumor diagnosis and treatment. However, the abnormal upregulation of cellular heat shock proteins (HSPs) induced by photothermal therapy (PTT) enhances cellular heat resistance, thereby severely affecting the efficacy of PTT. In this study, to address the impact of HSPs on the efficacy of PTT while obtaining high-quality NIR fluorescence imaging in the NIR region, we designed a targeted peptide@ICG nanofluorescent probe encapsulated in liposomes. The introduced cRGD targeting peptide not only possesses tumor-targeting capabilities but also features LA as the last amino acid in the targeting peptide, which can generate nitric oxide (NO) under reactive oxygen species (ROS) triggering. It can happen under 808 nm single-light source NIR light, and the guanidine group in the peptide decomposes and combines with singlet oxygen molecules to generate NO gas molecules, thereby exerting an elevated photothermal effect by inhibiting the expression of HSP70. In addition, the nanoprobes enable deep imaging and treatment of glioma in situ and can be combined with a laser speckle contrast imaging (LSCI) system for multimodal imaging. This composite probe demonstrates synergistic tumor therapeutic effects of photodynamic therapy (PDT), PTT, and gas therapy, offering a promising strategy for cancer treatment.
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JOURNAL OF NANOBIOTECHNOLOGY
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2024
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IF 10.6
Shaojie Dong,Yuwei Zhang,Yifei Zhang,Yukun Mei,Ahmadi Sina,Rui Zou,Lin Niu
Considering the high recrudescence and the long-lasting unhealed large-sized wound that affect the aesthetics and cause dysfunction after resection of maxillofacial malignant skin tumors, a groundbreaking strategy is urgently needed. Photothermal therapy (PTT), which has become a complementary treatment of tumors, however, is powerless in tissue defect regeneration. Therefore, a novel multifunctional sodium nitroprusside and Fe 2+ ions loaded microneedles (SNP-Fe@MNs) platform was fabricated by accomplishing desirable NIR-responsive photothermal effect while burst releasing nitric oxide (NO) after the ultraviolet radiation for the ablation of melanoma. Moreover, the steady releasing of NO in the long term by the platform can exert its angiogenic effects via upregulating multiple related pathways to promote tissue regeneration. Thus, the therapeutic dilemma caused by postoperative maxillofacial skin malignancies could be conquered through promoting tumor cell apoptosis via synergistic PTT—gas therapy and subsequent regeneration process in one step. The bio-application of SNP-Fe@MNs could be further popularized based on its ideal bioactivity and appealing features as a strategy for synergistic therapy of other tumors occurred in skin. Graphical Abstract Supplementary Information The online version contains supplementary material available at 10.1186/s12951-024-02409-4.
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MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
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2024
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IF 4.2
Xin Shao,Siqi Han,Yang Kang,Xuewen Yang,Lin Yang,Qihan Zhang,Xiaomin Wang
The plasma-silane coupling agent synergistically modified the hollow glass microsphere (HGM) process, blended with epoxy resin (EP), to prepare an acoustic matching layer suitable for the gas ultrasonic transducers. In comparison to the traditional NaOH solution stirring co-hydroxylation process, the plasma treatment method can rapidly activate the surface activity of HGM, leading to the generation of a large number of hydroxyl groups on the HGM surface. This process eliminates the need for mechanical stirring and cleaning steps, thus reducing the damage degree of HGM and the loss degree of surface hydroxyl groups . The results indicate that the amination modification effect of HGM treated with plasma is more pronounced, and the HGM/EP composite material exhibits better compatibility and density. The assembled ultrasonic transducer exhibits a sensitivity of up to 1.58 V, showing an improvement of nearly 61.2 % compared to the reference ultrasonic transducer with a sensitivity of 0.98 V. Furthermore, the calibrated testing of the gas ultrasonic flowmeter using the improved ultrasonic transducer demonstrates a percentage error absolute value below 0.7 % and a measurement result standard deviation below 0.15 %, demonstrating better measurement accuracy and consistency. This study aims to provide a new feasible process for improving the performance of gas ultrasonic transducers and ultrasonic flowmeters.
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APPLIED SURFACE SCIENCE
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2024
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IF 6.3
Wei Yang,Hao Cui,Mi Wang,Xiaohui Weng,Guolong Lu,Zhiyong Chang,Youhong Sun
Methane detection is crucial in identifying combustible ice within the energy sector. The gas–liquid separation membrane, a key component of methane sensors, plays a critical role in effectively separating methane and water. It significantly enhances the efficiency and stability of detecting methane concentration in situ. However, the related permeability and mechanical property present conflicting requirements in order to achieve optimal membrane performance. This work proposes an investigation into the mass transfer performance of a high-strength composite membrane, utilizing PDMS as the functional layer and porous ceramics as the supporting layer. By adjusting the pore distribution of the porous ceramics, particularly through the use of spherical graphite as a porogen, the study examines the impact of spherical graphite (SG) on the support layer’s morphology and its ability to regulate pore structure. Results indicate that incorporating spherical graphite with a porogen content of 10 wt% and a particle size of 25 μm enhances connections between ceramic grains, resulting in a flexural strength of 56.36 MPa and a permeability coefficient of 1861.57 barrer. This configuration demonstrates good waterproof and breathable performance. Overall, this research presents a novel approach for fabricating methane-water separation membranes, offering valuable insights for underwater methane detection efforts.
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ACS Applied Materials & Interfaces
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2025
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IF 8.2
Yi Wang,Liang Li,Fangli Zhang,Huajiang Wang,Zhaoliang Cui,Zhaohui Wang,Xiaozu Wang
Mixed matrix membranes (MMMs) can significantly improve gas separation performance, but the type and state of the filler in the membrane matrix are key indicators for the development of MMMs. Therefore, in this work, 6FDA-DAM/ODA (1:1), metal–organic frameworks (MOFs) with different particle sizes (UiO-66 and UiO-66-NH2) were synthesized, and then MOFs were doped into 6FDA-DAM/ODA to prepare MMMs. The effects of the dopant materials and their particle sizes on the gas separation performance of the membranes were investigated by testing the permeability of the MMMs to H2, CO2, CH4, and N2. When the dopant material was UIO-66, the permeability and selectivity of MMMs for each gas were significantly improved compared with that of the original membrane; when the dopant material was 300 nm UIO-66-NH2 with a loading of 10 wt %, the permeability performance and the CO2/CH4 selectivity increased from 44.1 to 57.2 compared with that of the original membrane. The permeation performance for CO2, N2, and H2 and the selectivity for CO2/N2, H2/N2, and H2/CH4 were also significantly improved. In terms of comprehensive separation performance, doping 300 nm UiO-66-NH2 was better than doping 70 and 400 nm UiO-66-NH2 and also showed excellent performance in 50:50 (vol/vol) CO2/CH4 binary mixed gas separation. This work provides an idea for the fabrication of MMMs for high-performance gas separation.
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ELECTROPHORESIS
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2024
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IF 3
Zhi-Yong Gao,Xi-Jin Li,Yuan-Yuan Cui,Cheng-Xiong Yang
The large surface area, excellent thermal stability and easy modification make microporous organic networks (MONs) good candidates in the field of gas chromatography (GC). Due to the limited species and highly conjugated networks of MONs, their applications are still in infancy and restricted. To accelerate their developments and to enrich their types in GC, here we report the first example of synthesizing alkyl MON and its capillary column for GC separation of position isomers. Linear 1,8-dibromooctane is used as the alkyl monomer instead of traditional aromatic ones to construct novel alkyl MON to decrease the inherent conjugated characteristic of MONs. The alkyl MON exhibits good thermal stability (up to 350°C), large surface area (1173 m 2 g −1 ), and non-polar character, allowing good resolution for alkanes, alkyl benzenes, alcohols, ketones, and diverse position isomers, including dichlorobenzene, trichlorobenzene, bromotoluene, nitrotoluene, methylbenzaldehyde, and ionone with the limits of detection (0.003 mg mL −1 ) and limits of quantitation of (0.10 mg mL −1 ). The in situ growth–prepared alkyl MON column demonstrates remarkable duration time and precisions for the retention relative standard deviations, (RSDs%, intra-day, n = 7), 0.06%–0.53% (intra-day, n = 7), and 2.87%–10.59% (column-to-column, n = 3). In addition, the fabricated alkyl MON-coated capillary column offers better resolution than three commercial GC columns for the resolution of methylbenzaldehyde, bromotoluene, and chlorotoluene isomers. This work reveals the practicability for synthesizing alkyl MONs and demonstrates their prospects for position isomers separation.
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Biomaterials Research
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2024
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IF 8.1
Lin Liu,Yucen Yao,Yang Liu,Bingrong Hong,Ziqing Li,Xuejun Chen,Yaofeng Zhang,Hongbo Fu,Degong Yang,Chunrong Yang
Management of myocardial ischemia–reperfusion injury (MIRI) in reperfusion therapy remains a major obstacle in the field of cardiovascular disease, but current available therapies have not yet been achieved in mitigating myocardial injury due to the complex pathological mechanisms of MIRI. Exogenous delivery of hydrogen sulfide (H 2 S) to the injured myocardium can be an effective strategy for treating MIRI due to the multiple physiologic functions of H 2 S, including anti-inflammatory, anti-apoptotic, and mitochondrial protective effects. Here, to realize the precise delivery and release of H 2 S, we proposed the targeted H 2 S-mediated gas therapy with pH-sensitive release property mediated by platelet membranes (PMs). In this study, a biomimetic functional poly(lactic-co-ethanolic acid) nanoparticle (RAPA/JK-1-PLGA@PM) was fabricated by loading rapamycin (RAPA; mTOR inhibitor) and JK-1 (H 2 S donor) and then coated with PM. In vitro observations were conducted including pharmaceutical evaluation, H 2 S release behaviors, hemolysis analysis, serum stability, cellular uptake, cytotoxicity, inhibition of myocardial apoptosis, and anti-inflammation. In vivo examinations were performed including targeting ability, restoration of cardiac function, inhibition of pathological remodeling, and anti-inflammation. RAPA/JK-1-PLGA@PM was successfully prepared with good size distribution and stability. Utilizing the natural infarct-homing ability of PM, RAPA/JK-1-PLGA@PM could be effectively targeted to the damaged myocardium. RAPA/JK-1-PLGA@PM continuously released H 2 S triggered by inflammatory microenvironment, which could inhibit cardiomyocyte apoptosis, realize the transition of pro-inflammation, and alleviate myocardial injury demonstrated in hypoxia/reoxygenation myocardial cell in vitro. Precise delivery and release of H 2 S attenuated inflammatory response and cardiac damage, promoted cardiac repair, and ameliorated cardiac function proven in MIRI mouse model in vivo. This research outlined the novel nanoplatform that combined immunosuppressant agents and H 2 S donor with the pH-sensitive release property, offering a promising therapeutic for MIRI treatment that leveraged the synergistic effects of gas therapy.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2025
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IF 9
Peng Gao,Bohao He,Yu Tian,Chi Wang,Xin Sun,Ping Ning,Kai Li,Fei Wang
Hydrogen fluoride (HF) gas is a major combustion byproduct in non-ferrous metal smelting, aluminum electrolysis, coal combustion, and waste incineration processes. Due to its high corrosivity and toxicity, which pose a serious threat to human health and environmental ecosystems, it is necessary to strictly control HF emissions from industrial processes or remove it using proper methods. In this study, an oxygen vacancy-containing magnesium-based adsorbent (2NC@Mg(NO 3 ) 2 –500) was successfully synthesized via a one-pot method. This adsorbent demonstrated a maximum HF adsorption capacity of 195.65 mg·g −1 (at 90 % efficiency), significantly exceeding values reported in previous literature. The basic sites of magnesium oxide (MgO) were critical for promoting HF dissociation, while oxygen vacancies facilitated HF adsorption and its conversion to magnesium fluoride (MgF 2 ). Density functional theory (DFT) calculations further confirmed the experimental findings, demonstrating that oxygen vacancies significantly enhance HF adsorption on MgO by stabilizing fluoride ions (F - ) at the vacancy sites. The subsequent consumption of these vacancies and the conversion of MgO to MgF 2 led to adsorbent deactivation. This study highlights the important role of oxygen vacancies in HF gas adsorption.
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