Journal of Functional Foods
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2020
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IF 3.701
Lvqi Zhou,Ning Hao,Xiaotian Li,Jiaxi Chen,Runyu Yang,Changqin Song,Yang Sun,Qi Zhang
In this study, we investigated the protective effect of Nattokinase (NK), the most active ingredient in natto used for healthcare, on dextran sulfate sodium (DSS)-induced chronic colitis and unraveled the potential mechanisms. NK dramatically attenuated clinical symptoms and pathological damage of DSS-induced chronic colitis. NK also inhibited proinflammatory cytokines production in DSS-induced colonic tissues. Mucosal integrity was maintained by NK. Moreover, nattokinase reversed DSS-induced decline of bacteria community diversity and intestinal microbial imbalance by decreasing levels of Firmicutes and increasing levels of Bacteroidetes . Tryptophan (Trp) metabolism analysis demonstrated that NK suppressed Trp catabolism especially the Kynurenine (Kyn) pathway in chronic colitis. Furthermore, NK strikingly down-regulated the protein expression of IDO-1 in chronic colitis mice. Taken together, the study demonstrated that NK relieved DSS-induced chronic colitis by regulating gut microbiota and suppressing Trp metabolism via inhibiting IDO-1. This study indicated that NK might be a promising and effective agent for IBD.
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CATALYSIS LETTERS
·
2021
·Vol. 151
·期 9
·2513-2526
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IF 3.186
Cui Kai,Qian Wei,Shao Zhengjiang,Zhao Xiuge,Gong Honghui,Wei Xinjia,Wang Jiajia,Chen Manyu,Cao Xiaoming,Hou Zhenshan
Furfural (FFR) is one of the most important biomass-derived chemicals. Its large-scale availability calls for the exploration of new transformation methods for further valorization. Herein, we demonstrate that Ru nanoparticles (Ru NPs)-supported on a sulfonated carbon layer coated SBA-15 can be employed as an efficient bi-functional catalyst for one step conversion of FFR into 1,4-pentanediol (1,4-PeDO). The optimum bi-functional catalyst can afford the full the conversion of FFR and 86% selectivity to 1,4-PeDO. The catalysts have been characterized thoroughly by using a complementary combination of powder X-ray diffraction, N 2 adsorption–desorption, scanning/transmission electron microscopy, Fourier transform infrared spectroscopy, elemental analysis, and X-ray photoelectron spectroscopy. The characterization revealed that acidic groups (–SO 3 H) have been introduced on the surface of the carbon layer coated SBA-15 support after sulfonation with 98% H 2 SO 4 and the surface acidity can be tuned facilely by the sulfonating time. Meantime, Ru(0) sites was highly dispersed via an impregnation and sequential reduction and directly adjacent to the surface –SO 3 H group. There existed an electronic interaction between Ru(0) sites and sulfonic groups, in which the electronic transfer from sulfonic sites to Ru(0) sites occurred. Brönsted acid sites (–SO 3 H) have a significant influence on the FFR conversion and the selectivity to 1,4-PeDO. The ordered mesoporous structure, the appropriate density of acid sites and the electron-rich Ru(0) sites accounted for the the excellent performance of the catalyst for an efficient production of 1,4-PeDO from FFR. Graphic Abstract
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ANALYTICA CHIMICA ACTA
·
2020
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IF 5.977
Jiating Zheng,Shuyao Huang,Yuanjun Tong,Songbo Wei,Guosheng Chen,Siming Huang,Gangfeng Ouyang
The secretion disorder of sex hormones is the source that leads to the occurrence of many diseases such as polycystic ovarian syndrome (PCOS), hyperandrogenism and so on. There exist physiological changes in human body when slight fluctuations in concentrations of sex hormones happen. Therefore, it’s of great significance for accurate detection of sex hormones in human body. In this work, TpPa-1 COF solid-phase microextraction (SPME) fiber was prepared using high-efficient in-situ synthesis strategy and coupled with HPLC-MS/MS to detect three sex hormones, including Progesterone (P), testosterone (T) and dehydroepiandrosterone (DHEA) in human serum. The thickness of the coating reached 7 μ m within 2 h. Under the optimal conditions, the established method presented low limit of detections (LODs, ≤ 0.75 ng/mL), wide linear ranges (0.100–100 ng mL −1 ) and good reproducibility, and three sex hormones (T, P, DHEA) were successfully detected and quantified in human serum. In conclusion, the established SPME method presented high-efficient fiber preparation and good analytical performances of sex hormone detection, therefore was in great potential for application in clinical.
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PubMed
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RSC Advances
·
2020
·Vol. 10
·期 20
·11643-11651
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IF 3.119
Qi Xia,Hong Peng,Lin Yuan,Lifang Hu,Yu Zhang,Roger Ruan
The exploration of a highly efficient and environment-friendly solvent for dissolving hemicellulose is significant. In this study, 1-butyl-3-methylimidazolium carboxylate ([Bmim]carboxylate)-based ionic liquids (ILs), including [Bmim]formate, [Bmim]acetate, [Bmim]propionate, and [Bmim]butyrate, were used as solvents to dissolve arabinoxylan-rich hemicellulose from bamboo. The hemicellulose solubility in the ILs was determined as a function of temperature. The interaction between the hemicellulose and the ILs was evaluated by using 1H and 13C NMR techniques. The hemicelluloses regenerated from the saturated IL solutions were characterized. Results showed that the temperature and structure of carboxylate anions deeply affected the hemicellulose solubility. The carboxylate anion played a more important role than the imidazolium cation in hemicellulose dissolution. The hydrogen bond that formed between the ILs and the hydroxyl groups at the XC2 position of xylopyranose units of hemicellulose was stronger than that between the ILs and the hydroxyl groups at XC3 position of xylopyranose units. The hydrogen bond strength between the hemicellulose and the ILs was affected by the alkyl chain of the carboxylate anion and the hemicellulose concentration. The disruption of the inter- and intra-molecular hydrogen bonds in hemicellulose by the ILs was responsible for the hemicellulose dissolution. The main chain of hemicellulose remained nearly unchanged during the dissolution process.
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CHINESE JOURNAL OF CATALYSIS
·
2020
·
IF 6.146
Xuemei Li,Junying Tian,Hailong Liu,Congkui Tang,Chungu Xia,Jing Chen,Zhiwei Huang
A highly efficient and green process was developed for the synthesis of useful 5-amino-1-pentanol (5-AP) from biomass-derived dihydropyran by coupling the in situ generation of 5-hydroxypentanal (5-HP, via the ring-opening tautomerization of 2-hydroxytetrahydropyran (2-HTHP)) and its reductive amination over supported Ni catalysts. The catalytic performances of the supported Ni catalysts on different oxides including SiO 2 , TiO 2 , ZrO 2 , γ-Al 2 O 3 , and MgO as well as several commercial hydrogenation catalysts were investigated. The Ni/ZrO 2 catalyst presented the highest 5-AP yield. The characterization results of the oxide-supported Ni catalysts showed that the Ni/ZrO 2 catalyst possessed high reducibility and a high surface acid density, which lead to the enhanced activity and selectivity of the catalyst. The effect of reaction parameters on the catalytic performance of the Ni/ZrO 2 catalyst was studied, and a high 5-AP yield of 90.8% was achieved in the reductive amination of 2-HTHP aqueous solution under mild conditions of 80 °C and 2 MPa H 2 . The stability of the Ni/ZrO 2 catalyst was studied using a continuous flow reactor, and only a slight decrease in the 5-AP yield was observed after a 90-h time-on-stream. Additionally, the reaction pathways for the reductive amination of 2-HTHP to synthesize 5-AP were proposed.
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CHEMICAL ENGINEERING JOURNAL
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2020
·
IF 10.652
Liyu Zheng,Sanyuan Hu,Heping Li,Youwei Yan
The fast development of optoelectronics makes a huge boost to the searching for flexible indium-free transparent conductors. In recent years, metal networks (currently are Au, Ag and Cu) have emerged as promising alternatives, however, facile fabrication of high-performance, chemically stable, and low-cost transparent conductor is still a big challenge. Here, ultra-long W microfibers (with conductivity of 4.3 × 10 4 S/cm) are successfully produced by draw spinning and further assembled into well-regulated patterns. Such a solution-processed patterning effectively eliminates the fiber-to-fiber joint resistance, and thus enables the W network to achieve an ultra-low sheet resistance of 0.2 Ω sq −1 at ~90% transparency, which corresponds to a high figure of merit σ dc /σ opt = 1.7 × 10 4 (up to 10–40 times the value of Cu and Au networks). Moreover, the W network possesses excellent anti-thermal and anti-corrosion properties, which enable it to work in the erosion solution with pH ranging from 1 to 13 with a restrained increase (<3%) in its sheet resistance. With a marvelous combination of high conductivity and transparency, high chemical stability and good mechanical flexibility, the ultrathin W fibers may open a new door to find flexible indium-free transparent conductors for the development of both flexible electronics and energy conversion.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2020
·Vol. 31
·期 11
·8489-8495
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IF 2.22
Shi Liang,Zhang Huaiwu,Shi Xiaolei,Liu Cheng,Peng Rui,Wang Gang,Wang Xueying
Excellent microwave ceramics play a dominant role in current 5G communication technology and Internet of things technology. In current work, high-quality factor of Li 2 Mg 3 TiO 6 - x BaV 2 O 6 (LMT- x BV 2 , x = 0.1, 0.3, 0.4, 0.5, 0.6) ceramics were synthesized via the traditional solid-state reaction method. Phase composition, microstructure, microwave dielectric properties and co-firing compatibility with silver were investigated systematically. The sintering temperature of LMT ceramics was successfully reduced from 1280 °C to below 950 °C with the addition of BV 2 ceramics. In particular, when x value was 0.1, high-quality factor 90,100 GHz (at 10 GHz), a permittivity 14.3 and τ f value − 65 ppm/°C were gained when sintered at 900 °C for 4 h. The linear approximation formula was used to qualitatively illustrate the relationship between microstructure and microwave dielectric properties. The good chemical compatibility of LMT-0.1BV 2 with silver provides a good candidate for LTCC processing.
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APPLIED CATALYSIS B-ENVIRONMENTAL
·
2020
·
IF 16.683
Wangyang Wang,Wei Zhou,Wei Li,Xuewei Xiong,Yuhao Wang,Kang Cheng,Jincan Kang,Qinghong Zhang,Ye Wang
Maximizing the use of palladium without compromises in catalytic activity and stability in the combustion of methane is extremely challenging due to the harsh operation conditions. To achieve this goal, a series of core-shell-structured catalysts with different amounts of palladium nanoparticles confined in hydrophobic silicalite-1 (Pd@S-1) was designed. Unexpectedly, a volcanic trend between catalytic activity and palladium loading was found as the loading increased from 0.3 wt% to 1.6 wt%, among which the 0.6 wt%Pd@S-1 exhibited the highest catalytic activity with a complete combustion temperature of 380 °C. Besides, the 0.6 wt%Pd@S-1 showed an ultrahigh stability in the high temperature applications due to the spatial confinement of palladium inside the rigid zeolite matrix. Moreover, owing to the hydrophobicity of the pure silica zeolite, the Pd@S-1 could selectively hinder the diffusion of water vapor into the palladium sites, leading to the outstanding water-resistance ability.
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LIFE SCIENCES
·
2020
·
IF 3.647
Xiuhuan Chen,Cui Zhang,Yan Guo,Xin Liu,Tianxin Ye,Yuhong Fo,Chuan Qu,Jinjun Liang,Shaobo Shi,Bo Yang
Aim The purpose of the study was to investigate what effects the sigma-1 receptor (S1R) could exert on the cardiac myocyte ion channels in a rodent model of depression and to explore the underlying mechanisms since depression is an independent risk factor for cardiovascular diseases including ventricular arrhythmias (VAs). Materials and methods To establish the depression model in rats, chronic mild unpredictable stress (CMUS) for 28 days was used. The S1R agonist fluvoxamine was injected intraperitoneally from the second week to the last week for 21 days in total, and the effects were evaluated by patch clamp, western blot analysis, and Masson staining. Key findings We demonstrated that depression was improved after treatment with fluvoxamine. In addition, the prolongation of the corrected QT (QTc) interval under CMUS that increased vulnerability to VAs was significantly attenuated by stimulation of S1R due to the decreased amplitude of L-type calcium current (I Ca-L ) and the restoration of reduced transient outward potassium current (I to ) resulting from CMUS induction. The S1R also decelerated I to inactivation and accelerated I to recovery by activating Ca 2+ /calmodulin-dependent kinase II. Moreover, the stimulation of S1R ameliorated the structural remodeling as the substrate for maintenance of VAs. All these effects were abolished by the administration of S1R antagonist BD1047, which verified the roles for S1R. Significance Activation of S1R could decrease the vulnerability to VAs by inhibiting I Ca-L and restoring I to , in addition to ameliorating the CMUS-induced depressive symptoms and structural remodeling.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2020
·Vol. 31
·期 13
·9974-9981
·
IF 2.22
Fan Xuemin,Li Peng,Du Juan,Chen Chong,Fu Peng,Hao Jigong,Yue Zhenxing,Li Wei
The (1 − x )[0.935(Bi 0.5 Na 0.5 )TiO 3 –0.065BaTiO 3 ]– x Ba(Zr 0.3 Ti 0.7 )O 3 (BNT–BT– x BZT) ceramics with high-energy storage properties were designed and characterized. All the BNT–BT– x BZT ceramics exhibit a pure perovskite structure. The grain size of ceramics becomes larger as the BZT content increases. Enhanced energy density performances ( W rec = 1.9 J/cm 3 , η = 86%) are achieved for the BNT–BT–0.4BZT ceramics at 210 kV/cm. Specifically, the energy stored in the material can be rapidly released within 0.27 µs. Excellent temperature stability with the variation of W rec less than 7% is realized in a wide temperature range from 20 to 140 °C. Moreover, the energy storage performances have good reliability after 10 5 electric field cycles. The high-energy storage performances indicate that the BNT–BT–0.4BZT ceramics are promising candidates in pulsed-power applications.
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Journal of Advanced Ceramics
·
2020
·Vol. 9
·期 3
·292-302
·
IF 2.889
Wang Hongxian,Zhao Peiyao,Chen Lingling,Li Longtu,Wang Xiaohui
Multilayer ceramic capacitors (MLCCs) for energy storage applications require a large discharge energy density and high discharge/charge efficiency under high electric fields. Here, 0.87BaTiO 3 -0.13Bi(Zn 2/3 (Nb 0.85 Ta 0.15 ) 1/3 )O 3 (BTBZNT) MLCCs with double active dielectric layers were fabricated, and the effects of inner electrode and sintering method on the energy storage properties of BTBZNT MLCCs were investigated. By using the pure Pt as inner electrode instead of Ag 0.6 Pd 0.4 alloys, an alternating current (AC) breakdown strength ( BDS ) enhancement from 1047 to 1500 kV/cm was achieved. By investigating the leakage current behavior of BTBZNT MLCCs, the Pt inner electrode and two-step sintering method (TSS) were confirmed to enhance the Schottky barrier and minimize the leakage current density. With relatively high permittivity, dielectric sublinearity, and ultra-high BDS , the Pt TSS BTBZNT MLCCs exhibited a surprisingly discharge energy density ( U dis ) of 14.08 J/cm 3 . Moreover, under an operating electric field of 400 kV/cm, the MLCCs also exhibited thermal stability with U dis variation < ±8% over a wide temperature ( t ) range from -50 to 175 °C and cycling reliability with U dis reduction < 0.3% after 3000 charge-discharge cycles. These remarkable performances make Pt TSS BTBZNT MLCCs promising for energy storage applications.
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JOURNAL OF NUCLEAR MATERIALS
·
2020
·
IF 2.485
Yi Ding,Zhengdi Jiang,Tianheng Xiong,Zimei Bai,Dandan Zhao,Hui Dan,Tao Duan
Zircon is important ceramic used widely due to its excellent properties, in particular for nuclear waste immobilization . However, it is difficult to obtain mono-phase zircon with high yield, usually result in double-phase ZrO 2 /ZrSiO 4 ceramics. Herein, Ce-doped double-phase 0.2Zr 1- x Ce x O 2 /Zr 1- y Ce y SiO 4 (0 ≤ x + y ≤ 1) ceramics were fabricated and their phase and microstructure evolution were studied. The results demonstrated that Ce content has great influence on the phase composition and microstructure. The ceramics with 0 ≤ x + y < 0.1 are tetragonal-ZrSiO 4 , monoclinic-ZrO 2 and tetragonal-ZrO 2 phases, with 0.1 ≤ x + y ≤ 0.3 are tetragonal-ZrSiO 4 , monoclinic-ZrO 2 , tetragonal-ZrO 2 and cubic-ZrO 2 phases, with 0.3 < x + y ≤ 0.6 are tetragonal-ZrSiO 4 , tetragonal-ZrO 2 and cubic-ZrO 2 phases, and with 0.6 < x + y ≤ 1 are cubic-ZrO 2 and Ce 2 Si 2 O 7 phases. With increasing Ce-doping content, the ZrSiO 4 retained the tetragonal phase, while ZrO 2 transformed from monoclinic to stable cubic phase. Furthermore, lattice parameters , grain size and compactness increased with increasing Ce content.
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