CHINESE JOURNAL OF POLYMER SCIENCE
·
2020
·Vol. 39
·期 4
·493-500
·
IF 3.154
Meng Xiao-Yu,Li Yi,Yao Shu-Fang,Wei Xue-Wei,Ye Hai-Mu
Spherulites are the most common crystalline morphology and thus the visual expression of crystal structures for polymers. The diversified patterns have provided intuitive morphology probes for various crystallization behaviors, while the correlations between them are still needed to be enriched. In this work, the complicated spherulitic morphology of poly(propylene fumarate) (PPF), which is sensitive to crystallization temperature, is investigated. PPF melt, respectively, crystallizes into rough spherulites, regularly banded spherulites, and spherulites containing both two kinds of morphology at low, high, and mediate temperatures. By systematically assaying, it is clear that the growth axis along the radial direction changes from a -axis to b -axis as the crystallization temperature increases, which leads to the formation of unique crystallization-temperature-dependent spherulites. Based on detailed characterization of Fourier transform infrared spectroscopy, the packing state of the specific hydrogen bonds of “C=C-H⋯O=C-C=C” in PPF crystal lattices is determined, and furthermore, the mechanism for temperature-dependent selection of growth axes for PPF spherulites in melt is reasonably speculated.
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高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-17
·
IF 14.7
Wu Min,Wang Tingting,Ji Nan,Lu Ting,Yuan Ran,Wu Lingxiang,Zhang Junxia,Li Mengyuan,Cao Penghui,Zhao Jiarui,Li Guanzhang,Li Jianyu,Li Yu,Tang Yujie,Gao Zhengliang,Wang Xiuxing,Cheng Wen,Ge Ming,Cui Gang,Li Rui,Wu Anhua,You Yongping,Zhang Wei,Wang Qianghu,Chen Jian
Glioblastoma (GBM) is the most common brain tumor and remains incurable. Primary GBM cultures are widely used tools for drug screening, but there is a lack of genomic and pharmacological characterization for these primary GBM cultures. Here, we collect 50 patient-derived glioma cell (PDGC) lines and characterize them by whole genome sequencing, RNA sequencing, and drug response screening. We identify three molecular subtypes among PDGCs: mesenchymal (MES), proneural (PN), and oxidative phosphorylation (OXPHOS). Drug response profiling reveals that PN subtype PDGCs are sensitive to tyrosine kinase inhibitors, whereas OXPHOS subtype PDGCs are sensitive to histone deacetylase inhibitors, oxidative phosphorylation inhibitors, and HMG-CoA reductase inhibitors. PN and OXPHOS subtype PDGCs stably form tumors in vivo upon intracranial transplantation into immunodeficient mice, whereas most MES subtype PDGCs fail to form tumors in vivo. In addition, PDGCs cultured by serum-free medium, especially long-passage PDGCs, carry MYC/MYCN amplification, which is rare in GBM patients. Our study provides a valuable resource for understanding primary glioma cell cultures and clinical translation and highlights the problems of serum-free PDGC culture systems that cannot be ignored.
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PubMed
高影响因子
Scientific Reports
·
2017
·Vol. 7
·期 1
·1-11
·
IF 4.259
Zhao Jiangtao,Zhang Peng,Wang Zhuo,Zhang Shijie,Gao Hongqing,Hu Junhua,Shao Guosheng
In the field of photocatalysis, the high-charge recombination rate has been the big challenge to photocatalytic conversion efficiency. Here we demonstrate the direct evidence of multichannel-improved charge-carrier mechanism to facilitate electron-hole transfer for raising photocatalytic H 2 evolution activity. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), and UV-Vis diffuse reflectance spectroscopy (DRS), were used to characterize the as-fabricated samples. The result shows that the present design of Au/Pt nanoparticles (NPs) decorated one-dimensional Z-scheme TiO 2 /WO 3 heterostructure composite nanofibers have been fabricated, which even exhibited excellent light absorption in the visible region and greatly enhanced photocatalytic activities on H 2 generation comparing with pure TiO 2 , TiO 2 /WO 3 and Pt/WO 3 /TiO 2 nanofibers. This greatpromotion is mainly on account of the photosynthetic heterojunction system, which include the surface plasmon resonance (SPR) of Au nanoparticles, low overpotential of Pt nanoparticles, and more importantly, the one-dimensional multichannel-improved charge-carrier photosynthetic heterojunction system with Pt as an electron collector and WO 3 as a hole collector. Transferring photoinduced electrons and holes at the same time, leading to effective charge separation was directly proved by ultraviolet photoelectron spectroscopy, electrochemical impedance spectroscopy, photocurrent analysis and incident photon-to-electron conversion spectrum.
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高影响因子
BULLETIN OF MATERIALS SCIENCE
·
2020
·Vol. 43
·期 1
·1-6
·
IF 1.392
Li Dan,Wang Yuxiang,Guo Meng,Song Mingjun,Ren Yang
Ethylene glycol (EG)-based hybrid nanofluids containing graphene oxide–silver nanosheets (GO–Ag) were simply prepared without using any surfactant. The graphene oxide–silver composites were characterized using X-ray diffraction analysis, transmission electron microscope, infrared and UV–visible spectroscopy. The stability of GO–Ag nanofluids was estimated by UV–visible spectroscopy. The GO–Ag/EG hybrid nanofluids has good stability without significant sedimentation for 60 days. A few thermophysical properties of GO–Ag/EG nanofluids with 0.1, 0.2 and 0.3 wt% nanosheets were analysed experimentally at different temperatures ranging from 20 to 50°C.
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高影响因子
CHROMATOGRAPHIA
·
2020
·Vol. 83
·期 8
·985-992
·
IF 1.596
Zhao Yang,Zeng Jiao,You Junheng,Duan Yuanxing,Li Yuandong,Liu Chunbo,Liu Zhihua,Yang Liu,Shen Qinpeng,Li Zhenjie
A poly ( N -isopropyl acrylamide) (polyNIPA)-based hybrid column for capillary liquid chromatography (cLC) was prepared with N -isopropyl acrylamide (NIPA) and alkoxysilanes through a sol–gel “one-pot” method. In this process, the hydrolyzed tetramethoxysilane (TMOS) and vinyltrimethoxysilane (VTMS) were the precursors for the synthesis of a silica-based monolith and subsequently reacted with organic monomer (NIPA) via free radical polymerization within the confines of a capillary. The effects of polymerization temperature, the volume of TMOS, VTMS, and acetic acid (HAc) as well as the amount of progens [polyethylene glycol 10,000 (PEG10000) and urea] on the morphology and permeability were investigated in detail. Uniform pore structure and good mechanical stability were obtained for columns prepared under optimized conditions. Separation of various neutral, acidic and basic analytes was achieved by cLC in reversed-phase liquid chromatography (RP-LC) mode. Moreover, the resulting hybrid column was also applied for the analysis of small organic pollutants, including polycyclic aromatic hydrocarbons (PAHs), perfluorinated compounds (PFCs) and chlorophenols (CPs). The successful application demonstrated its potential in the separation of small molecules.
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高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2021
·Vol. 32
·期 17
·22024-22034
·
IF 2.478
Li Hong,Jiao Jinxu,Ye Qi,Wu Zhixin,Luo Donglian,Xiong Dehua
Quantum dots (QDs) attract extensive attention because of their excellent optoelectronic performance. However, few research has been done on the synthesis of core–shell QDs by one-step thermal injection. Here the CdSe/ZnS core–shell QDs were successfully synthesized by a one-step thermal injection method. The synthesis process of CdSe/ZnS core–shell QDs was investigated from two aspects of reaction time and oleic acid dosage. The results suggest that the reaction time and the dosage of oleic acid have important effects on the optical properties of CdSe/ZnS core–shell QDs. The action mechanism of oleic acid was also explained in this paper. Moreover, highly efficient green quantum dot light-emitting diodes (QLEDs) were fabricated with CdSe/ZnS core–shell QDs on ITO glass substrate by rotary coating method. The minimum starting voltage of 1.91 V and the maximum brightness of 12,057 cd m −2 were achieved in the QLEDs. This study is of great significance for the development of the synthesis of core–shell QDs by one-step thermal injection and QLEDs.
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高影响因子
MICROCHIMICA ACTA
·
2013
·Vol. 180
·期 13
·1325-1332
·
IF 3.434
Wu Ying,Feng Xun,Zhou Shenghai,Shi Hongyan,Wu Hongmin,Zhao Shujie,Song Wenbo
We report on a sensor for epinephrine (EP) that is based on an ITO electrode modified with multi-walled carbon nanotubes pre-coated with a polymerized ionic liquid (PIL-MWNTs). A chitosan film was then electrodeposited on the ITO electrode in the presence of EP (the template) and the PIL-MWNTs. This film acts as an excellent recognition matrix due to its excellent film-forming ability and the many functional groups that favor hydrogen bond formation with the target (EP). The PIL-MWNTs, in turn, can improve the sensing performance due to their good electrical conductivity, high dispersity, and large surface area. The imprinted films were characterized by scanning electron microscopy, X-ray diffraction, Fourier transform IR spectroscopy, and thermogravimetric analysis. The electrochemistry of the imprinted electrode was investigated by cyclic voltammetry, electrochemical impedance spectroscopy, differential pulse voltammetry and chronoamperometry. The response to EP is linear in the 0.2 μM to 0.67 mM concentration range, and the detection limit is as low as 60 nM (at an S/N of 3). The electrode is reusable and offers good reproducibility and stability.
An epinephrine imprinted electrode was facile achieved by electrodepositing chitosan on ITO surface in the presence of epinephrine and polymerized ionic liquid-functionalized carbon nanotubes, followed by removal of the epinephrine template molecule. Specific recognition of EP molecule and its determination were realized at this imprinted sensor.
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高影响因子
MICROCHIMICA ACTA
·
2014
·Vol. 182
·期 5
·1197-1204
·
IF 3.719
Zhong Anni,Luo Xiaoli,Chen Liping,Wei Shanshan,Liang Yonghong,Li Xinchun
We describe a new electrochemical platform for direct sensing of glucose. The electrode was prepared by controlled electrodeposition of nickel nanoparticles onto carbon nanotubes on a copper electrode. The sensor was optimized by investigating the effects of the concentration of nickel precursor, electrolysis time and acidity of the medium. The nanocomposite was characterized by scanning electron microscopy and energy dispersive spectroscopy. Cyclic voltammetry of glucose in 0.1 M NaOH solution gives a well-defined anodic wave with a peak potential at 0.53 V (vs. Ag/AgCl) that indicates the direct electrooxidation of glucose at the nanomaterial. The electrode responds to glucose over a wide linear range (from 2 μM to 10 mM), with high sensitivity (3.8 mA∙mM −1 ∙cm −2 ) and a low detection limit (0.7 μM). The sensor was applied to the determination of glucose in blood samples, and the results were in good agreement with data obtained by a commercially available glucometer. The method holds promise due to the ease of sensor fabrication and its robust performance and longevity.
An enzyme-free glucose amperometric sensor based on nickel nanoparticle-carbon nanotubes modified copper electrode is described. The sensor is easily fabricated and shows excellent analytical performance.
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高影响因子
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
·
2018
·Vol. 124
·期 12
·1-13
·
IF 1.604
Li Yueqin,Zhou Minya,Li Yun,Gong Qiang,Wang Yiting,Xia Zongbiao
High performance alkoxy-functionalized polythiophene (PM4EOT) and TiO 2 nanocomposites were prepared via a facile in situ oxidative chemical polymerization of thiophene monomer. The morphology studied demonstrated that nanocomposites were of the core–shell structure with a particle size of approximately 30 nm and PM4EOT shell was of about 2–10 nm thickness. X-ray photoelectron spectroscopy (XPS) spectra proved that there was a new Ti–S interaction between the polymer and TiO 2 surface. The supercapacitive behaviors of the nanocomposites investigated by cyclic voltammetry galvanostatic charge–discharge and AC impedance measurements demonstrated that the prepared PM4EOT/TiO 2 nanocomposite [1:1 (weight ratio)] exhibits enhanced specific capacitance and cycling stability as compared to the two pristine components and various ratio contents. The specific capacitance of PM4EOT/TiO 2 nanocomposite (1:1) was obtained up to 111 F/g at a current density of 0.5 A/g, which is much higher than that of the pure PM4EOT (45 F/g) and TiO 2 (1.6 F/g). In addition, the energy density of 15.4 Wh kg −1 and the power density of 308 W kg −1 delivered by composite (1:1) capacitor were achieved at a current density of 0.5 A/g.
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高影响因子
IONICS
·
2022
·Vol. 28
·期 12
·5571-5580
·
IF 2.961
Wu Meijuan,Wang Liwei,Xu Fugang,Ma Guangran
A Ni-MOF superstructure composed of 2D nanosheet (2D Ni-MOFss) was prepared and further combined with reduce graphene oxide (rGO) for electrochemical detection of acetaminophen (AP). The structure and properties of the 2D Ni-MOFss were characterized by SEM, XRD, XPS, and electrochemical method. The loosened 2D lamella structure endowed the 2D Ni-MOFss with improved electrocatalysis and low charge transfer resistance than bulky Ni-MOF. After integration with rGO, the composite 2D Ni-MOFss/rGO shows significantly enhanced catalysis for redox reaction of AP with high current response and low over-potential. An electrochemical sensor for AP based on the 2D Ni-MOFss/rGO shows a wide linear range of 0.036 to 50 μM, and a low detection limit of 0.012 μM. The sensor with high sensitivity, good selectivity, and stability also show satisfied recovery for detecting AP in real sample. The facile preparation and enhanced catalysis make these 2D MOF composite attractive materials for electrochemical sensors.
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高影响因子
Nano Research
·
2024
·
IF 9.5
Liu Dong-Xue,Deng Xin,Zhu Yong-Fu,Meng Zhe,Sun Xue-Feng,Shi Miao-Miao,Zhong Hai-Xia,Yan Jun-Min
Electrocatalytic reduction of nitrate \(({\rm{N}}{{\rm{O}}_3}^ - )\) and nitride \(({\rm{N}}{{\rm{O}}_2}^ - )\) to ammonia (NH 3 ) is of wide interest as a promising alternative to the energy-intensive Haber-Bosch route for mitigating the vast energy consumption and the accompanied carbon dioxide emission, as well as benefiting for the relevant sewage treatment. However, exploring an efficient and low-cost catalyst with high atomic utilization that can effectively facilitate the slow multi-electron transfer process remains a grand challenge. Herein, we present an efficient hydrogenation of \({\rm{N}}{{\rm{O}}_3}^ - /{\rm{N}}{{\rm{O}}_2}^ - \) species to NH 3 in both alkaline and neutral environments over the Fe 2 (MoO 4 ) 3 derived hybrid electrocatalyst with the metallic Fe site on FeMoO 4 (Fe/FeMoO 4 ). The Mo ingredient can play a synergistically positive role in further promoting the NH 3 production on Fe. As a result, Fe/FeMoO 4 behaves well in the electrochemical NH 3 generation from \({\rm{N}}{{\rm{O}}_2}^ - \) with a maximum NH 3 Faradaic efficiency (FE) of 96.53% and 87.68% in alkaline and neutral electrolyte, corresponding to the NH 3 yield rate of 640.68 and 302.56 \({\rm{mg}} \cdot {{\rm{h}}^{ - 1}} \cdot {\rm{m}}{{\rm{g}}_{{\rm{cat}}.}}^{ - 1}\) , respectively, which outperforms the Fe and Mo counterpart and other similar catalyst, showing the robust catalytic capacity of each active site.
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高影响因子
Scientific Reports
·
2021
·Vol. 11
·期 1
·1-13
·
IF 4.38
Hu Pan,Shen Shaohang,Yang Hu
Two series of binary graft cationic starch-based flocculants (CS-DMCs and CS-DMLs) with different hydrophilicity and charge density (CD) were prepared by graft copolymerization of acrylamide with 2-(Methacryloyloxy)- N , N , N -trimethylethanaminium chloride and methacrylic acid 2-(benzyldimethylaminio) ethyl chloride, respectively, on the starch (St) backbone. The sludge dewatering performance of CS-DMCs and CS-DMLs were evaluated and compared based on the changes in filter cake moisture content (FCMC), specific resistance of filtration (SRF), fractions and components of extracellular polymeric substances, and various physiochemical characteristics of sludge flocs and cakes. Increase in CD of the St-based flocculants caused improved sludge dewaterability. Under the similar CD, CS-DML with relatively high hydrophobicity exhibited lower FCMC and SRF, larger and denser sludge flocs, and better permeability of sludge cakes than CS-DMCs due to the synergistic effects of charge neutralization, bridging flocculation and hydrophobic association. Furthermore, a second-order polynomial model on the basis of phenomenological theory was successfully applied to quantitatively evaluate the influences of the two important structural factors of these St-based flocculants, i.e., hydrophobicity and CD, on the sludge dewaterability. The structure–activity relationship of the St-based flocculants in sludge dewatering was obtained according to the theoretic simulation. The dewatering mechanisms was discussed in depth on the basis of the experimental and simulated results; besides, the FCMC and optimal dose can be predicted by the established structure–activity relationship. This current work offered a novel and valuable way to exploit and design of low-cost and high-performance graft natural polymeric flocculants applied in efficient conditioning of sludge.
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高影响因子
危险品化学品经营许可证（带存储）