APPLIED SURFACE SCIENCE
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2022
·
IF 7.392
Jiarong He,Tao Tao,Fan Yang,Zhipeng Sun
Sodium-ion batteries (SIBs) are prospective and fascinating for stationary energy storage systems (ESS) because of the abudance of sodium (Na) resource and their excellent cycle stability. Exploring for advanced anode materials with robust framework and appropriate crystallographic sites, is of great significance to effectively boost the practical applications of SIBs and to largely decrease the potential safety issues of alloy-type anodes with large volume changes during cycling. Herein, two hydrated vanadium phosphates [K 3 V 3 (PO 4 ) 4 ·H 2 O, KVP] are delicately prepared by freeze-drying and sol–gel heating drying, denoted as KVP-FD and KVP-HD, respectively, and used as novel anodes for SIBs to reveal their Na + intercalation mechanism. KVP-HD electrode possesses a much superior discharge capacity and a higher capacity retention (185.6 mAh g −1 , 72.2 %) at 1C for 300 cycles, and more excellent rate capability at high C-rates (greater than1C) than KVP-FD (127.4 mAh g −1 , 45.5 %). Cyclic voltammetry, galvanostatic intermittent titration and electrochemical impedance spectroscopy, manifest a more alleviated polarization, smaller impedance and faster diffusion kinetics of KVP-HD electrode than KVP-FD. Exsitu -X-ray diffraction ( exsitu -XRD) further reveals that polyanionic KVP-HD material possesses a robust structure and provides fast ion diffusion tunnels to reversibly (de)intercalate the Na + /K + due to the pillar K + residing and holding the structure. The electrochemical mechanism switch successively from an initial predominant K + to a subsequent mixed Na + /K + (de)intercalation in the polyanionic KVP during cycling. This work innovatively lights up the future to use Na-free KVP polyanion as robust framework for advanced anode in SIBs, which gives insightful reference for using Na-free materials for next-generation SIBs anodes towards a much safer and a more cost-effective battery system.
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FOOD CHEMISTRY
·
2022
·
IF 9.231
Swati Mahato,Da-Wen Sun,Zhiwei Zhu
This work studied the effects of electromagnetic fields (EMF) with frequencies between 100 and 400 Hz and a fixed strength of 12 mT on cold storage of grass carp at 4 °C for 30 min, and Ca 2+ ATPase enzyme activities, and lipid and protein oxidations in samples were measured to assess changes in intracellular Ca 2+ concentration and oxidative stability. Results showed higher Ca 2+ ATPase activities in samples treated with EMF frequencies. Significant ( p < 0.05) decreases occurred in protein oxidation for samples treated between 100 and 300 Hz, but an increase was observed for treatment with 400 Hz. However, the lipid oxidation increased for samples treated up to 200 Hz and decreased with further increase in frequency to 300 and 400 Hz. Nuclear magnetic resonance analysis showed that exposure to different frequencies of EMF could reduce the association of water molecules with protein for both bound and immobilized water. Overall, treatments of EMF between 100 and 400 Hz could improve grass carp quality during cold storage.
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2022
·
IF 9.136
Wensen Liu,Hui Su,Jian Zhang,Lina Wang,Yahui Liu,Jie Liang,Zhaowu Zhu
The hydrometallurgical process for the recovery of nickel and cobalt requires a complex and expensive impurity removal process. Solvent extraction is widely used in industry for the separation, purification, and concentration of metals. However, current commercial extractants encounter some difficulties when cobalt and nickel are extracted from solutions containing a large amount of impurities such as manganese and calcium. There is an urgent need to develop new reagents for the selective extraction of Ni and Co. In this study, N-(2-ethylhexyl)-pyridine-4-carboxamide (NEHPCA) was synthesized, and the metal extraction capacity of its synergistic solvent extraction (SSX) system with dinonylnaphthalene sulfonic acid (DNNSA) and tributyl phosphate (TBP) modifier was examined. The experimental results show that the selectivity of the new SSX system has the order Cu > Ni > Co > Zn > Mn > Ca > Al ≈ Cr (III) ≈ Mg ≈ Fe (III), with excellent selectivity for nickel and cobalt. Using an organic phase composed of 0.7 M NEHPCA, 0.35 M DNNSA, and 0.2 M TBP under 1:1O/A operation, after three-stage theoretical extraction, more than 99% of nickel and cobalt can be recovered from a synthetic leaching solution of nickel laterite ore. Mechanistic studies showed that NEHPCA and water molecules participate in the internal coordination of metals, and DNNSA provided coordination anions to achieve charge balance, forming the Ni complex in this SSX system which existed most likely in the form of [Ni(NEHPCA) 2 (H 2 O) 4 ](DNNS) 2 in the organic phase.
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高影响因子
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
·
2022
·
IF 7.088
Qidong Tang,Ting Peng,Jie Hu,Tao Zhang,Pengqin Chen,Daoxing Chen,Yunjie Wang,Lingfeng Chen,Linjiang Tong,Yi Chen,Hua Xie,Guang Liang
Pan-HER inhibitors exhibit extensive biological activity and offer unique advantages and usually bind to targets in an irreversible manner. Owing to the off-target toxicity of irreversible inhibitors, reversible pan-HER inhibitors are desirable. Herein, we describe the process of N -(ring structure fused phenyl)quinazoline-4-amine-based design, synthesis, and biological evaluation of pan-HER inhibitors in vitro and in vivo . Compound C5 , with the molecular skeleton of N -(3-bromo-1 H -indol-5-yl)-quinazolin-4-amine, displayed irreversible binding just like other effective pan-HER inhibitors. To our surprise, compound C6, which possessed the same skeleton, was found to be a high-strength reversible pan-HER inhibitor. This compound was capable of inhibiting HER1s (such as EGFR T790M/L858R and WT), HER2, and HER4 and can be considered as a breakthrough in the development of pan-HER inhibitors. Altogether, N -(3-bromo-1 H -indol-5-yl)-quinazolin-4-amine can serve as an effective molecular skeleton for developing both reversible and irreversible pan-HER inhibitors in the following discovery of antitumor drugs .
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高影响因子
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
·
2021
·
IF 6.514
Xing-Rong Wang,Shuai Wang,Wen-Bo Li,Kai-Yan Xu,Xue-Peng Qiao,Xue-Li Jing,Zi-Xiao Wang,Chang-jiang Yang,Shi-Wu Chen
Vascular endothelial growth factor-2 (VEGFR-2) plays a pivotal role in tumor angiogenesis . Herein, a library of novel 2-(4-(1 H -indazol-6-yl)-1 H -pyrazol -1-yl)acetamide derivatives were designed and synthesized as VEGFR-2 inhibitors based on scaffold hopping strategy. These compounds exhibited the excellent inhibitory in both VEGFR-2 and tumor cells proliferation . Especially, compound W13 possessed potent VEGFR-2 inhibition with IC 50 = 1.6 nM and anti-proliferation against HGC-27 tumor cells with IC 50 = 0.36 ± 0.11 μM, as well as less toxicity against normal GES-1 cells with IC 50 = 187.46 ± 10.13 μM. Moreover, W13 obviously inhibited colony formation, migration and invasion of HGC-27 cells by adjusting the expression of MMP-9 and E-cadherin, and induced HGC-27 cells apoptosis by increasing ROS production and regulating the expression of apoptotic proteins. Furthermore, W13 blocked the PI3K-Akt-mTOR signaling pathway in HGC-27 cells. In addition, anti-angiogenesis of W13 was proved by inhibiting tube formation and the expression of p-VEGFR-2 in HUVEC cells. All the results demonstrated that W13 could be developing as a promising anticancer agent for gastric cancer therapy.
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高影响因子
CHEMOSPHERE
·
2023
·
IF 8.8
Huiwang Dai,Jingyi Zhu,Fanxu Meng,Daohui Lin,Wenjun Zhou,Dingjiang Chen,Ming Zhang,Qingqing Wang
In this study, Cu hybridization coupling oxygen defect engineering was adopted to synthesis of CuNiFe layered double oxides (CuNiFe-LDOs) in peroxymonosulfate (PMS) activation for degradation of methyl 4-hydroxybenzoate. The morphology and crystal structure of CuNiFe-LDOs was characterized in detail, which exhibited regular layered-structure at a Cu:Ni doping ratio of 1:1 and annealing temperature of 400 °C, and presented the crystal of Cu x O@Fe 3 O 4 –NiO. Besides, the X-ray photoelectron spectroscopy (XPS) and electron paramagnetic resonance (EPR) results demonstrated that abundant oxygen vacancies (OVs) and low oxidation state Cu species were composed in CuNiFe-LDOs400. The Cu 1·5 Ni 1·5 Fe 1 -LDOs400/PMS system showed excellent catalytic performance toward the degradation of butyl 4-hydroxybenzoate (BuP), and resistant to the effect of pH value and background inorganic anions. Based on quenching experiments and EPR measurements, singlet oxygen ( 1 O 2 ) was identified as the dominant active species during the heterogeneous catalytic process, which was generated by the synergistic interaction between OVs-Cu(I) site and PMS . In this process, the electron-drawing property of OVs promoted the adsorption of PMS molecule on Cu(I) site, followed by the accumulation of electron and cleavage of O–O bond to generate intermediate oxygen radical species, which donated one electron to eventually generate singlet oxygen.
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高影响因子
JOURNAL OF FLUORESCENCE
·
2021
·Vol. 31
·期 4
·1125-1132
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IF 2.217
Wu Chuqiao,Lin Xin,Wang Qianming
The new design strategy will provide the possibility for preparing a dynamic sensor by employing the inhibition of C = N isomerization. In this work, the functional probe 4-(1 H-imidazo [4,5-f] [1,10]-phenanthrolin-2-yl) benzaldehyde oxime (compound 4 ) has been synthesized and such molecule gives rise to blue emission. Due to the incorporation of hypochlorite, the oxime group can be oxidized to the structure of aldehyde. As a result, the molecular motif exhibits sharp emission change from blue to green due to the addition of hypochlorite with enough sensitivity and selectivity (detection limit = 53 nM, linear range 0.5-8.0 µM). It has also been used for monitoring ClO − by employing solution color change and the absorption signal difference could effectively rule out the effects of interference species. To our knowledge, it will be the first case of a highly selective hypochlorite sensor derived from oxime isomerization reaction based on phenanthroline backbone.
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高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2021
·
IF 6.953
Jialin Liu,Ying Shao,Chunhong Yuan,Koichi Takaki,Yujin Li,Yubin Ying,Yaqin Hu
Effects of the eugenol-chitosan nanoemulsion as an edible coating on the quality of hairtail ( Trichiurus haumela ) during storage at 4 °C were evaluated. For all samples, such parameters as pH, thiobarbituric acid (TBA), total volatile basic nitrogen (TVB-N), water holding capacity (WHC), electrical conductivity (EC), total bacteria count (TVC) and sensory were examined periodically. The results demonstrated that eugenol-chitosan nanoemulsion coating showed better preservative effects than chitosan nanoemulsion alone. Therefore, a coating based on eugenol-chitosan nanoemulsion could be regarded as an effective food-grade biopreservative to maintain the quality of hairtail fish and prolong its shelf life during chilled storage.
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高影响因子
FOOD CHEMISTRY
·
2021
·
IF 7.514
Wenting Zhu,Yushun Zhou,Shuai Liu,Mei Luo,Jun Du,Jieping Fan,Hua Xiong,Hailong Peng
In this study, surface imprinting, magnetic separation, and fluorescent detection were integrated to develop a dual-recognition sensor (MF-MIPs), which was used for highly selective and sensitive detection of 4-nitrophenol (4-NP) in food samples. Silane-functionalized carbon dots (Si-CDs) participated in the imprinting process and were uniformly distributed into the MIPs layers. MF-MIPs sensor exhibited a high fluorescence response and selectivity based on the dual-recognition mechanism of imprinting recognition and fluorescence identification. The relative fluorescence intensity of MF-MIPs sensor presented a good linear relationship in the range of 0.08–10 μmol·L −1 with a low limit of detection (23.45 nmol·L 1 ) for 4NP. MF-MIPs sensor showed high anti-interference, as well as excellent stability and reusability. The 4-NP recovery from spiked food samples ranged from 93.20 to 102.15%, and the relative standard deviation was lower than 5.0%. Therefore, MF-MIPs sensor may be a promising method for 4-NP detection in food samples.
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高影响因子
ACS Omega
·
2021
·
IF 3.512
Junjun Yin,Duo Wang,Zhifeng Zheng,Yueyuan Ye,Shuirong Li,Xingyong Jia
Based on the characteristic that Ca2+ can react with 4-ethyl-2-methoxyphenol (EMP) to form a complexation with a phenol–calcium ratio of 4:1, a new extraction and purification method of EMP is developed for the first time in this work. At an optimum purification condition, 99.60% purity of EMP can be obtained through a reaction and decomposition operation. By combining a variety of characterizations, which consist of in situ Fourier transform infrared spectrometer (FTIR), nuclear magnetic resonance (NMR), inductively coupled plasma optical emission spectrometer (ICP-OES), gas chromatography–mass spectrometry (GC–MS)/flame ionization detector (FID), elemental analysis, and thermogravimetric analysis, the reaction mechanism of the coordination process is studied. It is demonstrated that there are three stages of the coordination reaction between Ca2+ and EMP. A neutralization reaction occurs in the first stage, while the second stage is a mixing reaction stage including neutralization and coordination reaction. When the reaction proceeds to the third stage, another coordination reaction occurs. Furthermore, phenol and ethanol are added as impurities in EMP. EMP with a purity of more than 99.50% can be obtained using this purification method. It confirms that this efficient method can achieve a good purification effect even for EMP solutions with complicated components.
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2020
·Vol. 56
·期 4
·3011-3023
·
IF 3.553
Wang Jing,Li Jing,Liu Yuanyuan,Wang Meiri,Cui Hongtao
The cycling stability of electrode materials is a key for Faraday supercapacitors (FSs), especially the structure-unstable Ni(OH) 2 . There exist various strategies for stabilizing the structure of Ni(OH) 2 such as cobalt ions doping and mechanical support from substrate. However, these strategies have their own disadvantages. On the other hand, the combination of two or more strategies has the serious issues in materials synthesis. In this work, a branched nanosheets-interlaced structure of Co 2+ /Co 3+ -doped Ni(OH) 2 is built by a method of precursor template, which effectively applies two strategies including ions doping and self-supportive structure. Due to the synergistic contribution of these two strategies, the cycling stability of as-prepared material is significantly enhanced. This material also presents excellent high-rate capacity, and the as-assembled asymmetric supercapacitors (ASCs) show both high energy and power densities. These results prove that the effective combination of ions doping and self-supportive structure strategies is a promising route for the preparation of Ni(OH) 2 -based electrode materials with high performance.
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Journal of Materials Research and Technology-JMR&T
·
2020
·
IF 5.289
Yufei Liu,Siyuan Jiang,Wei Yan,Jun Qin,Min He,Shuhao Qin,Jie Yu
In order to expand its application range in electronics and membrane industries, this paper aimed to develop polyamide 6 (PA6)/P ( N -(4-carboxyphenyl) maleimide-alt-triallyl isocyanurate) (PCT) composites with heat-resisting, thermally conductive and anti-moisture, by employing PCT as a reactive reinforcement material and applying irradiation for solid-state interfacial reaction (SSIR) between PCT and PA6. According to the results, the SSIR occurred between PA6 and PCT. Compared with non-SSIR PA6, the PA6/PCT composite with SSIR showed the highest heat resistance, thermal conductivity and anti-moisture absorption and its relative crystallinity ( X c ), glass transition temperature ( T g ), and heat deflection temperature ( HDT ), thermal conductivity and anti-moisture absorption were improved by 61.4, 24.0, 83.9, 18.5 and 40.2%, respectively. This is because that the chemical bond between the PCT surface and the PA6 matrix is formed by SSIR, which provides a theoretical basis either for the development of PA6 or other semi-crystalline polymers.
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