ANALYTICAL LETTERS
·
2024
·
IF 1.6
Yueting Ding,Yulan Song,Wei Xu,Qi Zhang,Yanwen Li,Qiangling Zhang,Qu Liang,Xun Bao,Dianlong Ge,Yan Lu,Lei Xia,Yawei Liu,Chaoqun Huang,Xue Zou,Chengyin Shen,Yannan Chu
Acetone is produced from fat metabolism which is increased in diabetic patients due to the disruption of glucose metabolism. Therefore, urinary acetone is expected to be a biomarker for noninvasive diagnosis of diabetes. Although several techniques have been developed for urinary acetone, none meet the clinical needs of automated multi-injection for numerous samples. In this study, we developed automated multi-injection gas chromatography-photoionization detection (AMI-GC-PID) to determine urinary acetone. First, we optimized the sample preprocessing during urine collection and storage before detection and established a standard protocol. The urine was immediately sealed in headspace bottles, stored at 20 °C for 1 h, and equilibrated for 20 min at 80 °C before analysis. Next we evaluated the repeatability of the method and the influence of the urine matrix. The relative standard deviations (RSDs) of the intra-day (nine measurements) and inter-day (three days) measurements were less than 5%. The recovery rate was 97.4% ± 4.6%. AMI-GC-PID was applied to determine urinary acetone in 44 diabetic patients and 29 healthy subjects. The median concentration of urinary acetone was much higher in diabetic patients than in healthy controls (2019 μg/L compared 699 μg/L). The results show that AMI-GC-PID possesses suitable analytical figures of merit for urinary acetone with broad applications in the noninvasive diagnosis of diabetes.
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高影响因子
MOLECULES
·
2024
·Vol. 29
·期 15
·3604
·
IF 4.2
Qiang Fu,Mingqiang Chen,Weixin Pang,Zengqi Liu,Zhen Xu,Xin Lei
The thermodynamic effect of octyl-β-D-glucopyranoside (OGP) on the formation of methane-1,3-dimethylcyclohexane (DMCH) hydrate was studied in this work. The thermodynamic equilibrium hydrate formation pressures between 275.15 K and 283.15 K were measured by the isothermal pressure search method. Different OGP aqueous solutions (0, 0.1, and 1 wt%) were used in this work. The experimental results show that OGP had no obvious thermodynamic inhibition on methane-DMCH hydrate formation when its concentration was low (0.1 wt%), whereas it had an inhibition on methane-DMCH hydrate formation when its concentration was high (1 wt%). The phase equilibrium hydrate formation pressure of the methane-DMCH-OGP system is about 0.1 MPa higher than that of the methane-DMCH system. The dissociation enthalpies of methane hydrate in different solutions remained uniform, which indicates that OGP was not involved in methane-DMCH hydrate formation. This phenomenon is explained from the perspective of the molecular structure of OGP. As a renewable and biological nonionic surfactant, the concentration of OGP in the liquid phase is low, so OGP can be added to the methane-DMCH system without significant thermodynamic inhibition.
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高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2015
·Vol. 22
·期 20
·15812-15820
·
IF 2.828
Wu Donghai,Lu Guanghua,Zhang Ran,Lin Qiuhong,Yan Zhenhua,Liu Jianchao,Li Yi
Combination of ozone together with electrolysis (ozone-electrolysis) is a promising wastewater treatment technology. This work investigated the potential use of carbon nanotube (CNT)-based gas diffusion cathode (GDC) for ozone-electrolysis process employing hydroxyl radicals (·OH) production as an indicator. Compared with conventional active carbon (AC)-polytetrafluoroethylene (PTFE) and carbon black (CB)-PTFE cathodes, the production of ·OH in the coupled process was improved using CNTs-PTFE GDC. Appropriate addition of acetylene black (AB) and pore-forming agent Na 2 SO 4 could enhance the efficiency of CNTs-PTFE GDC. The optimum GDC composition was obtained by response surface methodology (RSM) analysis and was determined as CNTs 31.2 wt%, PTFE 60.6 wt%, AB 3.5 wt%, and Na 2 SO 4 4.7 wt%. Moreover, the optimized CNT-based GDC exhibited much more effective than traditional Ti and graphite cathodes in Acid Orange 7 (AO7) mineralization and possessed the desirable stability without performance decay after ten times reaction. The comparison tests revealed that peroxone reaction was the main pathway of ·OH production in the present system, and cathodic reduction of ozone could significantly promote ·OH generation. These results suggested that application of CNT-based GDC offers considerable advantages in ozone-electrolysis of organic wastewater.
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高影响因子
FUEL
·
2024
·
IF 6.7
Shikun Tong,Yuemeng Ren,Kele Yan,Yanxin Jin,Pengfei Li,Jianbo Zhang,Zhiyuan Wang
The coupling deposition and plugging caused by hydrate formation and wax precipitation during the development of deep water natural gas resources bring new industrial challenges and theoretical difficulty. We designed a single-pass pipeline with two types to investigate deposition behavior and systematically performed the coupling deposition and plugging of hydrate and wax experiments in gas–liquid annular flow . The experimental results illustrate that the single solid phase of hydrate is covered layer sheet deposition, while the coupling solid phase of hydrate and wax is bulk aggregations arch bridge deposition. Meanwhile, the natural eddy zone in reducing pipeline accelerates coupling solid particles deposition. Our finds provided the first knowledge on the double effect that wax crystals inhibit particles adhesion and gel network increases aggregations arch bridge blockage. For the low water content in emulsion system, the gel network provides gathering place for hydrate particles, and the arch bridge structure formed by aggregations accelerates the pipeline blockage. The plugging time is shortened by up to 72.6% with the wax concentration increase from 0 wt% to 3 wt%. For the high water content in emulsion system, the majority of wax crystals adsorbed on the hydrate particles and reduce particles cohesion force, which increase the plugging time. Combined with the microscopic morphology evolution perspective of hydrate particles coupled wax, the coupling deposition of hydrate and wax in gas–liquid annular flow has four stages: gas–liquid flow, coupling solid phase formation, coupling solid phase deposition and sloughing, and coupling solid phase plugging. This study can provide theoretical support and design basis for flow assurance program of deep water gas fields and low temperature natural gas transportation pipelines.
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高影响因子
ANALYST
·
2019
·Vol. 144
·期 16
·4897-4907
·
IF 4.019
Rui-Qian Zhang,Zhan-Qing Liu,Yan-Ling Luo,Feng Xu,Ya-Shao Chen
Novel nanocomposites consisting of polystyrene-block-polybutadienyl polyhexamethylene dicarbamate-block-polystyrene (PS-b-HTPB5-b-PS) and multiwalled carbon nanotubes (MWCNTs) were designed and prepared via noncovalent interactions. Scanning electron microscopy and transmission electron microscopy observations showed that segregated networks of MWCNTs were formed due to the cladding of PS-b-HTPB5-b-PS, presenting a parallel-arranged topology of the MWCNTs in a continuous PS-b-HTPB5-b-PS phase, which improved the dispersibility of the MWCNTs. The nanocomposites were fabricated into vapor sensing elements to detect CH2Cl2 vapor in the environment, exhibiting excellent responsive sensitivity, reproducibility and a low limit of detection (LOD) of 1 ppm when exposed to CH2Cl2 vapor. The chain extension of HTPB overcame the fragility and improved the tenacity of the thin films, and the responsivity was optimized by adjusting the content of the MWCNTs and the length of the PS chains. The newly developed conductive composites can be applied as a promising vapor sensor to accurately monitor CH2Cl2 vapor in the environment.
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高影响因子
RENEWABLE ENERGY
·
2024
·
IF 9
Xiangjun Guo,Yun Huang,Yunheng Tang,Ao Xia,Xianqing Zhu,Xun Zhu,Qiang Liao
Mixed bacterial syngas fermentation is a promising carbon-neutral method for producing acetic acid and ethanol. However, the bacterial community and metabolic pathways were different in the growth and ethanol production stages, whereas the activity of the bacterial community greatly depended on the pH of the culture. In this study, the effect of pH on syngas fermentation performance and microbial community composition under continuous gas supply was investigated. The mixed bacteria grew fastest at a pH of 7, while a constant pH of 6 led to the highest ethanol concentration of 5.15 g L −1 , which was 160 % higher than that at pH 7. Based on this, a two-step pH regulation method was proposed in this study to improve the ethanol production. Initially, the culture pH was maintained at 7 to create optimal growth conditions. Once bacterial density stabilized, it was then changed to a pH 6 to promote ethanol production. By doing this, compared with the control group, the maximum ethanol concentration (5.85 g L −1 ) increased by 148.9 %, the ethanol production rate (2.41 g L −1 d −1 ) increased by more than 8 times. This two-step pH regulation method ensured a high bacterial density and effectively stimulated ethanol production during syngas fermentation.
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Advanced Healthcare Materials
·
2024
·
IF 10
Jing Wang,Yi Zhang,Huadong Chen,Yihan Wu,Jinliang Liu,Hailong Che,Yong Zhang,Xiaohui Zhu
Tumor microenvironment, characterized by dense extracellular matrix and severe hypoxia, has caused pronounced resistance to photodynamic therapy (PDT). Herein, it has designed an artificial nitric oxide (NO) nanotractor with a unique “motor-cargo” structure, where a photoswitching upconversion nanoparticle (UCNP) core serves as the optical engine to harvest NIR light and asymmetrically coated mesoporous silica (SiO 2 ) shell acts as a cargo unit to load nitric oxide (NO) fuel molecule (RBS, Roussin's black salt) and PDT photosensitizer (ZnPc, zinc phthalocyanine). Upon illumination by 980 nm light, the UCNP emits blue light to excite RBS salt and release NO gas. On one hand, NO is used as the driving force to propel the particle with a high speed of ≈194 µm s −1 that generates significant rupture stress (over 0.95 kPa) on cell membrane to promote cellular endocytosis and intratumoral penetration. On the other hand, NO enables to alleviate tumor hypoxia by inhibiting cellular respiration as an oxygen conserver. When the excitation is subsequently switched to 808 nm light, the UCNP emits red light, triggering ZnPc to produce large amount of reactive oxygen species for PDT treatment. This study explores Janus-typed nanostructures for cell-particle interaction and gas-assisted phototherapy, opening avenues for versatile bioapplications.
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高影响因子
Current Research in Food Science
·
2025
·
IF 7
Qian-qian Jia,Jia-xing Li,Sen Yang,Ding-ding Su
Ginger is widely acclaimed for its pungent aroma, nutritional benefits, and unique pharmacological properties, making it essential in culinary and medicinal applications. This study investigates volatile flavor profile differences in ginger resulting from various cultivation practices. Gas chromatography–ion mobility spectrometry (GC–IMS) was utilized to isolate and identify volatile compounds. Subsequent analyses, including relative odor activity values (ROAV) and multivariate statistical analysis, precisely identified key flavor compounds differentiating organically cultivated ginger from conventional field-grown varieties. A total of fifty-six volatile compounds were identified, comprising 17 esters, 4 alcohols, 7 ketones, 18 terpenoids, 6 aldehydes, and 4 miscellaneous compounds, with esters and terpenoids constituting over 50 % of total volatiles. Compounds such as α-phellandrene, β-citronellal, butyl 2-propenoate, 2-heptanone-D, and 3-octanone predominantly contributed lemon, banana, and citronella notes in organically cultivated ginger. In contrast, citral dominated in conventional ginger. This research significantly advances our understanding of ginger's aroma under varied cultivation conditions and demonstrates GC–IMS's utility in effectively profiling ginger flavor, thereby guiding improved cultivation and management.
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Dongshun Sai,Xiaoxiang Cheng,Peijie Li,Xinsheng Luo,Jin Wang,Haiqing Chang,Daoji Wu,Heng Liang
Substantial amounts of hazardous shale gas produced water (SGPW) were generated with the development of hydraulic fracturing and horizontal drilling technologies. While membrane technique has gained popularity for SGPW treatment, membrane fouling remains a significant obstacle. Herein, a novel pretreatment process of ferrate (Fe(VI)) oxidation enhanced by ferrous iron (Fe(II)) was suggested to mitigate ultrafiltration membrane fouling in the treatment of SGPW. Results indicated that Fe(II)/Fe(VI) (100/30 μM) pretreatment increased the terminal normalized flux from 0.18 to 0.47, while reducing the irreversible and reversible fouling resistances by 71.1 % and 83.6 %, respectively. Interfacial free energy assessment revealed that Fe(II)/Fe(VI) pretreatment significantly enhanced the repulsive forces between pollutants and the membrane. Furthermore, the water quality of SGPW was generally improved by Fe(II)/Fe(VI) treatment, in comparison with single Fe(VI) oxidation. The synergistic effect of Fe(II) and Fe(VI) facilitated pollutants aggregation and enhanced the conversion of organic contaminants. In general, the generated high-valent iron intermediates (Fe(IV)/Fe(V)) were key contributors to the synergistic process and prolonged the oxidation duration. Simultaneously, the formation of Fe(III) promoted the flocculation performance. This novel approach presents promise for effective SGPW treatment and membrane fouling mitigation.
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高影响因子
CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Qihua Sun,Yan Xu,Weijing Wang,Jun Sun,Jialin Li,Jin Li,Zhaofeng Wu,Haiming Duan
The detection of trimethylamine (TMA) is important not only for assessing the quality of seafood products but also for monitoring the environment. Biomass-derived carbon materials have been used for gas-sensitive detection because of their environmental friendliness, abundance, diversity, and chemical stability. In this work, the green waste of groundsel fibers (GFs) was used as a substrate, and ultrathin SnO 2 nanosheets were successfully grown in situ on GFs via a simple hydrothermal reaction (SnO 2 /CGFs). The structures and morphologies of the materials were characterized to detect TMA gas at room temperature. Compared with pure CGFs, SnO 2 /CGFs showed satisfactory selectivity for TMA (500 ppm), higher sensitivity, and a response/recovery time of 5.5/3.3 s. The SnO 2 /CGF sensor exhibits good long-term stability and repeatability for the detection of TMA gas. It exhibits good linearity in measuring TMA gas in the concentration range of 5–200 ppm with a theoretical detection limit of 0.475 ppm and monitored the spoilage process of sea bass at room temperature. The improved gas-sensitive performance of SnO 2 /CGFs is attributed to the unique microstructure, heterojunction formation, and abundance of oxygen species of SnO 2 on carbon tubes of biomass grown in situ.
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高影响因子
ENERGY
·
2025
·
IF 9.4
Xingxing Wang,Guancheng Jiang,Guoshuai Wang,Haozhe Chen,Lili Yang,Yinbo He,Tengfei Dong
A novel approach to enhance wellbore stability was put forth based on the wellbore rock properties and instability mechanism of the hydrate reservoir given the issue of wellbore instability when using water-based drilling fluid in drilling operations in weakly cemented muddy fine silt reservoirs of natural gas hydrates in the South China Sea. Three main strategies were used to increase the stability of reservoirs: enhancing the underwater connection between sandstone particles and clay minerals, preventing clay hydration from spreading and expanding, and strengthening the stability of hydration skeleton structure. An appropriate drilling fluid system was built with soil phase containing wellbore stabilizer. Sulfonic acid groups and electrostatic interaction were introduced based on the characteristics of underwater adhesion of mussels. Through the process of free radical polymerization, a zwitterionic polymer containing catechol groups named DAAT was prepared for application in natural gas hydrate reservoir drilling. DAAT is composed of tannic acid (TA), dimethyl diallyl chloride ammonium chloride (DMDAAC), 2-acrylamide-2-methylpropanesulfonic acid (AMPS) and acrylamide (AM). Experimental results from mechanical property testing reveal an adhesion force of up to 4206 nN between SiO 2 and 5 wt% DAAT, demonstrating its ability to bind quartz sand particles effectively. The compressive strength and cohesion of the cores treated with DAAT increased by 58.33wt% and 53.26wt%, respectively, at -10°C, compared with pure ice particle cores. This demonstrates DAAT can significantly enhance the compressive strength and cohesion of the core. Furthermore, the adhesion force between DAAT and hydrate particles reaches up to 344.4 mN/m, significantly improving the structural stability between hydrate particles. It demonstrates excellent adhesive properties to hydrate particles. In addition to adsorbing clay minerals, rocks, and hydrate particles, DAAT also forms hydrogen bonds with argillaceous fine silt particles with its low temperature cohesiveness characteristic. As a result, it improves the cohesion between core particles, and enhances the adhesion between hydrates and rocks, thereby enhancing the stability of hydrate reservoirs. In summary, DAAT is characterized by a simple preparation process, cost-effectiveness, and environmental friendliness. It is an innovative and practical material for enhancing wellbore stability in water-based drilling fluid for natural gas hydrate exploration in the South China Sea.
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高影响因子
Science China-Chemistry
·
2021
·Vol. 64
·期 10
·1796-1810
·
IF 9.445
Wu Cheng-Guang,Liang Jing-Lan,Wang Xiang,Zhou Xiaoyan,Cai Xiang,Xu Jun,Wang Meng,Wang Wen-Bo,Ma Dong,Xue Wei
The limited intratumoral perfusion of nitric oxide (NO)-carrying nanoparticles into solid tumors caused by the inherent biological barriers in vivo greatly attenuates their generated efficacy. Herein, through entrapping heat-sensitive NO donors (BNN6) on mesoporous polydopamine nanoparticles (M-PDA) and subsequently enveloping with red blood cells membranes, a heat-responsive biomimetic theranostic nanoerythrocyte (M/B@R) is developed to boost NO-based cancer therapy. The reserved intact structure of red blood cells membranes (RBCm) endows M/B@R with superior biosafety and stealth properties for prolonged circulation time and subsequent enhanced tumor accumulation. Once internalized in tumors and excited by near-infrared light (NIR, 808 nm) irradiation, M/B@R can not only yield plenty of heat for photothermal therapy (PTT) but also achieve the overproduction of NO for highly-efficient NO gas therapy due to its high loading capacity and NIR-absorbing property of M-PDA. The generated NO further ensures the formation of ONOO − which possesses remarkable toxicity to tumor as well as alleviating tumor hypoxia. It is found that M/B@R with NIR as the excitation source can significantly induce synthetic lethality to tumors via the hyperthermia, DNA damage and the ease of tumor hypoxia. Simultaneously, M/B@R also exhibits the potential for bimodal fluorescence and photothermal imaging. The RBCm-camouflaged NO delivery nanoplatform with bimodal imaging capability in this work may provide a new combinatorial paradigm to induce PTT/NO for cancer theranostic applications.
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高影响因子
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