Materials Today Communications
·
2022
·
IF 3.662
Qiao Zhao,Dongqin Xiao,Yuwei Li,Xinghan Chen,Kun Hu,Xuwei Luo,Fei Yang,Zelong Yang,Kang Liu,Gang Feng,Jinhui Liu,Daxiong Feng,Ke Duan
Osteonecrosis of the femoral head (ONFH) is a common disease with limited options of treatment. In this study, we prepared self-setting nano-sized hydroxyapatite carriers incorporating microspheres for controlled release of growth differentiation factor-5 (GDF-5) and/or alendronate (ALN). GDF-5 release enhanced the proliferation of rabbit bone mesenchymal stem cells (BMSCs), and ALN release inhibited the proliferation of macrophages. A rabbit ONFH model was created by liquid nitrogen infusion, and the carriers were implanted into the channel-shaped defects and harvested at 12 weeks. Imaging examination and histological analyses found that all carriers increased new bone formation in the defects, with the group simultaneously incorporating GDF-5 and ALN yielding the greatest improvement. The synergistic release of ALN and GDF-5 from the carrier may offer a promising option for the treatment of ONFH after surgical decompression.
✓ 已验证
DOI
高影响因子
MACROMOLECULES
·
2017
·
IF 5.835
Yan Wang,Ming-Zhe Lv,Nan Song,Zeng-Jie Liu,Chunyu Wang,Ying-Wei Yang
We report a new strategy to construct a multi-stimuli-responsive fluorescent supramolecular polymer by the strong host–guest interactions between a diselenium bond-bridged pillar[5]arene dimer and an AIE-active tetraphenylethylene (TPE)-containing neutral guest bearing two imidazole terminal binding sites. The resulting supramolecular polymer shows a remarkable fluorescence emission decrease at low concentration. Significantly, the diselenium bonds introduced into the supramolecular polymer serve as redox-responsive building blocks. Upon addition of reductants, the supramolecular polymer depolymerized owing to the cleavage of the covalent diselenium bonds in the system. On the other hand, competitive guests such as adiponitrile, which bind strongly with pillar[5]arenes, could lead the disassembly of the polymer to oligomers without breaking any covalent bonds in the system. These two types of depolymerization approaches can both result in the fluorescence intensity recovery of the system to a certain extent, which will hopefully enrich the methodology toward the construction of smart supramolecular polymeric materials with different properties.
✓ 已验证
DOI
高影响因子
INORGANICA CHIMICA ACTA
·
2020
·
IF 2.304
Li Li,Feifei Xing,Shourong Zhu
Two N 3 O 3 macrocyclic compounds with rigid chromogenic 1,8-dihydroxylenanthraquione and flexible diethylenetriamine/dipropenetriamine (L1 and L2), were synthesized and characterized. L1/L2 can interact with alkaline, alkaline-earth, as well as Zn 2+ , Pb 2+ , and Al 3+ chloride/perchloride evidenced by their DPV change and 1 H NMR spectra. Unexpectedly, both L1 and L2 can show chromogenic response to Na + , K + , and TBA + hydroxide (but not LiOH). Large cavity L2 can show chromic response to Ca(OH) 2 and Ba(OH) 2 , but L1 can only respond to Ca(OH) 2 in DMSO. L1 and L2 form 1:1 and 2:1 (Host:Guest) complex respectively with NaCl, NaOH, TBAOH in DMF/DMSO. Both hosts bind smaller Zn 2+ and Al 3+ in 2:1 in DMSO. L2 can form L2·TBAOH greenish yellow complex that gradually transformed to red L2 2 ·TBAOH in two steps in DMSO. Different from other macrocycles, L1 and L2 are ion-pair hosts that recognize cation and OH − via carbonyl groups.
✓ 已验证
DOI
高影响因子
RESEARCH ON CHEMICAL INTERMEDIATES
·
2023
·Vol. 49
·期 10
·4523-4539
·
IF 3.3
Guo Hui,Han Long,Baloch Humair Ahmed,Wang Zhonghui,Xia Jia,Zhang Chengkun,Yin Xuejian
Biomass-derived 5-Hydroxymethylfurfural (HMF) is a vital platform compound for synthesizing biofuel and various high-value chemicals. This work prepared carbonaceous solid acid catalysts with Brønsted acid and Lewis acid using pine biomass as raw materials through chloride salts impregnation, carbonization and sulfonation. The obtained catalysts were characterized by XRD, FTIR, SEM–EDS, BET, and Py-IR. The catalysts were applied to convert glucose into HMF in a biphasic system involving NaCl solution and γ-valerolactone. The results showed that the catalyst of PC-Al-SO 3 H exhibited larger microspheres and pore sizes compared with the sulfonated catalyst of PC-SO 3 H without AlCl 3 impregnation. Effects of key variables such as reaction temperature, reaction time on conversion of glucose into HMF were examined. By using PC-2Al-SO 3 H with stronger Lewis acid, glucose conversion and HMF yield achieved 86.53 mol% and 59.62 mol% at 160 °C and 6 h. The cyclic experiments revealed that PC-2Al-SO 3 H exhibited relatively stable activity.
✓ 已验证
DOI
高影响因子
Journal of the Iranian Chemical Society
·
2015
·Vol. 12
·期 12
·2149-2159
·
IF 1.087
Wu Kai-Fei,Jiang Fen,Bai Xian-Li,Mo Shao-Yin,Qin Gui-Fang,Feng Yu
The reactions of a semirigid carboxylic ligand 5-(Pyridin-3-yl)isophthalic acid(H 2 pyip) with Mn(CH 3 COO) 2 /Zn(NO 3 ) 2 /Pb(NO 3 ) 2 afforded three new complexes: [Mn(pyip)(H 2 O) 2 ] n ( 1 ), [Zn(pyip)(H 2 O) 2 ] n ( 2 ), and [Pb(pyip)] n ( 3 ). Their structures have been determined by single-crystal X-ray diffraction analyses and further characterized by elemental analyses, IR spectra, powder X-ray diffraction (PXRD), and thermogravimetric (TG) analyses. X-ray structure analysis reveals that complexes 1-2 showed identical 3D supramolecular architecture that just connect different metal centers. They all crystallize in hexagonal space group P6(5) and exhibit the same coordination mode. One of the H 2 pyip adopts bidentate chelate coordination mode, and the other coordinate carboxylate oxygen atom adopts the single dentate-bridging mode. Complex 3 adopts different coordination modes crystallized in monoclinic space group P2(1)/c compared to 1-2, combined bidentate chelate and chelating–bridging tetradentate coordination modes. A noticeable point in this paper is that compounds 1-3 exhibit preferable catalytic properties on degradation of Rhodamine B (RhB). Moreover, the luminescent properties were investigated.
✓ 已验证
DOI
高影响因子
Materials Today Sustainability
·
2023
·
IF 7.8
W. Dai,L. Zhang,R. Liu,Z. Huo,W. Dai,N. Guan
Zeolite catalysts with high propylene selectivity and superior stability are highly desirable in the methanol to propylene (MTP) conversion. Herein, plate-like MFI zeolites with different Si/Al (Ga) ratios were successfully prepared via a fluoride assisted strategy and applied in the MTP reaction. The influences of the zeolite morphology, acid density, and strength on the MTP activity as well as the reaction mechanism were clarified by combining spectroscopic and catalytic results. The plate-like MFI zeolites with lower acid density could efficiently suppress the aromatic-based cycle and promote the olefin-based cycle and thus exhibited a remarkable catalytic performance in the MTP conversion. However, owing to occurrence of irreversible hydrolysis of the Si-OH-Ga group during the MTP conversion, the catalytic activity of the Ga-MFI catalyst was not recyclable. On the contrary, the plate-like ZSM-5 catalyst shows excellent stability and recyclability in the MTP conversion.
✓ 已验证
DOI
高影响因子
JOURNAL OF CLUSTER SCIENCE
·
2020
·Vol. 32
·期 6
·1519-1529
·
IF 1.731
Soomro Najaf Ali,Amur Safdar Ali,Wei Yun,Shah Aamir Hassan,Jiao Mengzhao,Liang Hao,Yuan Qeping
Abstract Silver nanoparticles (AgNPs) are effective antibacterial agent but lack of stability and rapid aggregation limits their antibacterial efficiency in biomedical applications. To overcome these shortcomings, various strategies have been adopted so far but those strategies are not much effective at room temperature and in absence of external stimuli. Thus, herein, we have successfully grafted AgNPs into copper and guanosine 5′-monophosphate (Cu/GMP) metal organic frameworks at room temperature without using any external stimuli. The loading encapsulation ratio of AgNPs into Cu/GMP was approx. 99.83% at neutral pH. The AgNPs@Cu/GMP was characterized by various techniques, such as energy-dispersive x-ray spectroscopy, transmission electron microscopy, x-ray diffraction and Fourier transforms infrared spectroscopy. All these techniques have confirmed the loading of AgNPs into Cu/GMP (MOFs). Furthermore, antimicrobial activities of AgNPs, Cu/GMP and AgNPs@Cu/GMP were assessed against Escherichia coli (Gram-negative) and Staphylococcus aureus (Gram-positive) bacterium. As compared to pure AgNPs, the composite material AgNPs@Cu/GMP had shown significant growth of inhibition zones against tested bacteria. The stability of AgNPs@Cu/GMP was remarkable, i.e., six times higher than free AgNPs even after 15 days. These results make AgNPs encapsulated into Cu/GMP a promising antimicrobial candidate and is expected to deliver an advance platform to pharmaceuticals and biomedical applications. Graphic abstract
✓ 已验证
DOI
高影响因子
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
·
2020
·
IF 2.734
Kai An,Huiting Kang,Lilei Zhang,Lianxiong Guan,Dating Tian
Biocompatible thermosensitive molecularly imprinted polymers (MIPs) based on konjac glucomannan was prepared by graft copolymerization of N -isopropyl acrylamide , a thermosensitive monomer , with konjac glucomannan, a natural polysaccharide . The products were characterized by various means. The MIPs possessed switchable thermal regulation on the recognition and delivery of 5-fluorouracil (5-Fu), an anticancer drug . The results of adsorption experiments showed that the MIPs had excellent adsorption capacity at a temperature below the lower critical solution temperature, and the MIPs could specifically recognize and adsorb 5-Fu with good selectivity, repeatability, and stability. The adsorption isotherms of MIPs were fitted by six isothermal models and the dual-site Langmuir- Freundlich model presented the best fit. In addition, the in vitro release properties of 5-Fu from the thermosensitive MIPs were evaluated in phosphate buffer solution and the cumulative release of 5-Fu at 25 °C was higher than that at 38 °C. The release curves were fitted by zero-order, first-order, and Higuchi kinetic equations, respectively, and the results showed that the release of 5-Fu complied with the Fick 's law. Compared with non-molecularly imprinted polymers, the MIPs could release 5-Fu continuously for a certain period with a good controlled release effect, indicating that they possess great prospects as drug delivery materials.
✓ 已验证
DOI
高影响因子
Journal of the American Chemical Society
·
2017
·
IF 13.858
Shuai Xu,Peng Zhou,Zehui Zhang,Changjun Yang,Bingguang Zhang,Kejian Deng,Steven Bottle,Huaiyong Zhu
Selective oxidation of 5-hydroxymethylfurfural (HMF) to 2,5-furandicarboxylic acid (FDCA) is one of the key reactions for producing chemical commodities from biomass and their derivatives. The challenge for this reaction is to develop an efficient catalytic process that can be conducted under mild conditions (room temperature and atmospheric pressure, using oxygen molecules in air as the oxidant) and a recyclable catalyst. Herein we report a photocatalyst of cobalt thioporphyrazine (CoPz) dispersed on g-C3N4 (abbreviated as CoPz/g-C3N4), which exhibits excellent catalytic activity toward the selective oxidation of HMF into FDCA under simulated sunlight using oxygen molecules in air as a benign oxidant. For example, an FDCA yield of 96.1% in an aqueous solution at pH = 9.18 is achieved at ambient temperature and air pressure. At lower pH (4.01), the product generated is 2,5-diformylfuran. Hence, it is possible to control the reaction outcome by control of the pH of the reaction system. g-C3N4 itself is not a suitable catalyst for the selective oxidation because under the experimental conditions g-C3N4 generates hydroxyl radicals that initiate processes that oxidize HMF directly to CO2 and H2O. CoPz on the other hand activates O2 to give singlet oxygen (1O2), which more controllably oxidizes HMF to FDCA albeit at a more moderate yield (36.2%). The strong interaction between the CoPz and g-C3N4 in the CoPz/g-C3N4 catalyst is experimentally evidenced, which not only improves accessibility of the CoPz sites and makes the catalyst recyclable but also disables the hydroxyl radical generation by g-C3N4 and promotes 1O2 generation on the CoPz sites, significantly enhancing the catalytic performance. This study demonstrates the potential for efficient non-noble metal photocatalysts for organic transformations driven by sunlight.
✓ 已验证
DOI
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2013
·Vol. 36
·期 7
·1283-1290
·
IF 2.591
Shaolei Yang,Chunyan Chen,Zhihong Yan,Qingyun Cai,Shouzhuo Yao
Metal-organic frameworks, a new class of materials with high surface area and great porosity, have been widely applied in gas sorption. It is generally known that metal-organic framework 5 cannot be applied in aqueous phase since it is water sensitive. However, this work reveals that the derived material of metal-organic framework 5 is a good SPE sorbent that can be applied to aqueous phases. Metal-organic framework 5 was prepared and used as a SPE sorbent for the determination of polycyclic aromatic hydrocarbons in environmental matrices coupling with HPLC. The water treatment induced changes in the properties were investigated in detail. Even though metal-organic framework 5 is conversed to a second phase after water treatment, it still shows high extraction ability. Under the optimized experimental conditions, good sensitivity levels were achieved with low LODs ranging from 0.4 to 4.0 ng L −1 and a linearity of 0.004–20 μg L −1 ( R 2 > 0.996) for the investigated polycyclic aromatic hydrocarbons. The method has been validated in the analysis of real water samples with recoveries in the range of 80.2–120.2% and RSDs in the range of 0.5–11.7%.
✓ 已验证
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2019
·
IF 7.65
Weicheng Xu,Bingxu Chen,Xueding Jiang,Feng Xu,Xin Chen,Limin Chen,Junliang Wu,Mingli Fu,Daiqi Ye
The effect of Ca modification on the Ni/ZSM-5 catalyst for efficient toluene oxidation was studied in a plasma-catalytic system. The Ni/ZSM-5 and Ca-Ni/ZSM-5 catalysts were prepared by a wet impregnation method and characterized by X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET), Fourier transform infrared (FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS), Pyridine-FTIR spectroscopy and temperature programmed desorption of ammonia (NH 3 -TPD). Among the catalysts tested, the Ca-Ni/ZSM-5 sample showed the best potential for toluene conversion (90.2%) and CO 2 selectivity (70.7%). Pyridine-FTIR spectra and NH 3 -TPD results proved that the introduction of Ca and Ni onto ZSM-5 caused a decrease in the strong and weak acidic sites. In addition, gas chromatography/mass spectrometry (GC-MS) result showed that the Ca-Ni/ZSM-5 catalyst reduced the production of undesirable byproducts (such as p-nitrotoluene and methyl benzoate). Calcium in the Ni/ZSM-5 system influenced the acidity and other surface characteristic of the catalyst, as well as directly impacting the reactive plasma species and the intermediates. Finally, possible reaction mechanisms in the plasma catalysis of toluene were also proposed.
✓ 已验证
DOI
高影响因子
FUEL
·
2025
·
IF 7.5
Xuege He,Jiayu Shi,Chang Gao,Wenrong Che,Xianhai Zeng,Miao Zuo
This study presents a novel method for synthesizing biochar catalysts with multiple oxygen-containing functional groups, enabling the high-yield production of the biomass-derived platform compound 5-hydroxymethylfurfural (HMF) under mild conditions. Using an aqueous–methyl isobutyl ketone (MIBK) biphasic system, fructose conversion at 100°C for 4 h achieved an HMF yield of 92%. Furthermore, the roles of various functional groups on sulfonated biochar in substrate conversion were elucidated through molecular binding energy calculations, intermolecular weak interaction analysis, and frontier orbital theory. Detailed density functional theory (DFT) calculations further explored the catalytic mechanism, reaction energy barriers, and solvent effects in aqueous-phase fructose-to-HMF conversion. The results revealed that, compared to sulfate and sulfonic groups, hydroxyl and carboxyl groups on sulfonated biochar exhibited higher binding energies with fructose but lower energy gaps, facilitating electron exchange with reaction substrates and promoting nucleophilic side reactions. This study provides a solid theoretical foundation and valuable insights for the efficient and green synthesis of HMF using biochar catalysts in aqueous solvents.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）