Food Analytical Methods
·
2018
·Vol. 12
·期 1
·1-11
·
IF 2.245
Chang Qingyun,Zang Xiaohuan,Wu Tong,Wang Mengting,Pang Yachao,Wang Chun,Wang Zhi
A functionalized covalent organic framework (COF) was synthesized via room-temperature solvent-free mechano-chemical grinding method and used as a solid-phase extraction adsorbent for the extraction of eight biogenic amines (tryptamine, n-butylamine, phenylethylamine, cadaverine, putrescine, tyramine, spermine, and spermidine) in diverse meat samples. The target biogenic amines were derived with dansyl chloride to form stable fluorogenic derivatives for their high-performance liquid chromatography–fluorescence detection. The main important experimental parameters were investigated and optimized by both one-factor-at-a-time and response surface methodologies. Under the optimum conditions, a linear response for the biogenic amines was observed in the concentration range of 5.0–800.0 μg L −1 with the coefficients of determination ( r 2 ) ranging from 0.9944 to 0.9981. The limits of detection of this method (at a signal-to-noise ratio of 3) for the analytes ranged from 0.92 to 2.57 μg L −1 . The method recoveries of the target biogenic amines for five meat samples ranged from 80.3 to 115%, with relative standard deviations lower than 12%. The results indicate that the prepared COF is an effective adsorbent for the enrichment of biogenic amines.
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高影响因子
FIBERS AND POLYMERS
·
2018
·Vol. 19
·期 10
·2030-2038
·
IF 1.353
Sheng Chao,Zhou Yiming,Zhang Xinyu,Xue Guoxin
Cross-linked hydrogels of chitosan/poly(vinyl alcohol) (PVA)/oxidized cellulose nanowhiskers (CNWs) were prepared by using oxidized CNWs as a cross-linker. The effects of the oxidation level of CNWs on the swelling behavior, thermal stability, viscoelastic properties and compressive strength of the hydrogels were studied. Chemical cross-links, hydrogen bonds, as well as nanofiller reinforcement between the three materials played a major role in determining the properties of the hydrogels. Swelling test results showed that the incorporation of oxidized CNWs decreased the water absorbability of the hydrogels due to the increase in cross-linking degree. Viscoelastic properties of the hydrogels with oxidized CNWs was increased by 537 % in storage modulus, from 4.65 kPa to 29.6 kPa. Compressive strength of 181.5 kPa at 50 % strain was observed from the cross-linked hydrogels, compared with 21.2 kPa of the non-cross-linked hydrogels. The thermal experiments showed that the chemical cross-linking slightly increase the resistance toward thermal degradation of the hydrogels.
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International Journal of Oral Science
·
2024
·Vol. 16
·期 1
·1-16
·
IF 10.8
Chen Jiayao,Kuang Shuhong,Cen Jietao,Zhang Yong,Shen Zongshan,Qin Wei,Huang Qiting,Wang Zifeng,Gao Xianling,Huang Fang,Lin Zhengmei
The consumption of a high-fat diet (HFD) has been linked to osteoporosis and an increased risk of fragility fractures. However, the specific mechanisms of HFD-induced osteoporosis are not fully understood. Our study shows that exposure to an HFD induces premature senescence in bone marrow mesenchymal stem cells (BMSCs), diminishing their proliferation and osteogenic capability, and thereby contributes to osteoporosis. Transcriptomic and chromatin accessibility analyses revealed the decreased chromatin accessibility of vitamin D receptor (VDR)-binding sequences and decreased VDR signaling in BMSCs from HFD-fed mice, suggesting that VDR is a key regulator of BMSC senescence. Notably, the administration of a VDR activator to HFD-fed mice rescued BMSC senescence and significantly improved osteogenesis, bone mass, and other bone parameters. Mechanistically, VDR activation reduced BMSC senescence by decreasing intracellular reactive oxygen species (ROS) levels and preserving mitochondrial function. Our findings not only elucidate the mechanisms by which an HFD induces BMSC senescence and associated osteoporosis but also offer new insights into treating HFD-induced osteoporosis by targeting the VDR-superoxide dismutase 2 (SOD2)-ROS axis.
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PubMed
高影响因子
Discover Nano
·
2023
·Vol. 18
·期 1
·1-14
·
IF 0
Shao Runrun,Qiao Xiaofang,Cao Linlin,Man Jianliang,Guo Lingyun,Li Lanlan,Liu Wen,Li Lihong,Wang Bin,Guo Lixia,Ma Sufang,Zhang Boye,Wang Haojiang,Yan Lili
The development of nanoparticles capable of inducing reactive oxygen species (ROS) formation has become an important strategy for cancer therapy. Simultaneously, the preparation of multifunctional nanoparticles that respond to the tumor microenvironment is crucial for the diagnosis and treatment of tumors. In this study, we designed a Molybdenum disulfide (MoS 2 ) core coated with Manganese dioxide (MnO 2 ), which possessed a good photothermal effect and could produce Fenton-like Mn 2+ in response to highly expressed glutathione (GSH) in the tumor microenvironment, thereby generating a chemodynamic therapy (CDT). The nanoparticles were further modified with Methoxypoly(Ethylene Glycol) 2000 (mPEG-NH 2 ) to improve their biocompatibility, resulting in the formation of MoS 2 @MnO 2 -PEG. These nanoparticles were shown to possess significant Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) imaging capabilities, making them useful in tumor diagnosis. In vitro and in vivo experiments demonstrated the antitumor ability of MoS 2 @MnO 2 -PEG, with a significant killing effect on tumor cells under combined treatment. These nanoparticles hold great potential for CDT/photothermal therapy (PTT) combined antitumor therapy and could be further explored in biomedical research.
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Journal of Neuroinflammation
·
2024
·Vol. 21
·期 1
·1-24
·
IF 9.3
Wang Zhimeng,Liu Jing,Han Jing,Zhang Tianyi,Li Shangjin,Hou Yanfei,Su Huili,Han Fangping,Zhang Conggang
Accumulating evidence implicates that herpes simplex virus type 1 (HSV-1) has been linked to the development and progression of Alzheimer’s disease (AD). HSV-1 infection induces β-amyloid (Aβ) deposition in vitro and in vivo, but the effect and precise mechanism remain elusive. Here, we show that HSV-1 infection of the brains of transgenic 5xFAD mice resulted in accelerated Aβ deposition, gliosis, and cognitive dysfunction. We demonstrate that HSV-1 infection induced the recruitment of microglia to the viral core to trigger microglial phagocytosis of HSV-GFP-positive neuronal cells. In addition, we reveal that the NLRP3 inflammasome pathway induced by HSV-1 infection played a crucial role in Aβ deposition and the progression of AD caused by HSV-1 infection. Blockade of the NLRP3 inflammasome signaling reduces Aβ deposition and alleviates cognitive decline in 5xFAD mice after HSV-1 infection. Our findings support the notion that HSV-1 infection is a key factor in the etiology of AD, demonstrating that NLRP3 inflammasome activation functions in the interface of HSV-1 infection and Aβ deposition in AD.
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PubMed
高影响因子
CATALYSIS LETTERS
·
2021
·Vol. 152
·期 3
·781-790
·
IF 3.186
Yao Jie,Sheng Mengdi,Bai Shiyang,Su Hongjing,Shang Hui,Deng Han,Sun Jihong
Three mesoporous silica materials (MCM-41, MSN and BMMs) possessing different morphologies but similar hexagonal arranged mesopores with almost the same pore size (2–3 nm) were functionalized by Zn and [1-(trimethoxysilyl)propyl-3-methylimidazolium] ionic liquid (ILs) via post-grafting treatment. The ILs grafted mesoporous silicas were then characterized by porosity, microscopy and SAXS techniques, and the successful loading of Zn and ILs, as well as the different distribution of functional groups in different supports were shown. Furthermore, the cycloaddition reaction of CO 2 with epoxide was employed to evaluate the influences of the ILs distribution, which was proved to be caused mainly by varying morphologies of different supports. All the catalysts showed good catalytic activities. Interestingly, at low temperature, the inter particle supported ILs in BMMs had the highest catalytic efficiency, while the aggregation grafting ILs on MCM-41 present the lowest activity. However, the mesoporous silicas with ordered arranged nanopores present the superiority at higher temperature. The results highlight the crucial role played by the morphology of the supports. Graphical abstract
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Nano Research
·
2020
·Vol. 14
·期 4
·969-975
·
IF 8.183
Yang Lu,Zou Yuan,Xia Wei,Li Haotian,He Xinyu,Zhou Yi,Liu Xianhu,Zhang Chaoqun,Li Yiwen
Discovery and development of new sustainable photothermal materials with tunable light absorption spectra play a key role in solar energy harvesting and conversion. One possible solution to this quest is to check nature as a source of matters or inspiration. Inspired by the formation of tea stains, a unique class of dark stain materials generated by the interfacial reaction between tea polyphenols and metal substance, we reported the facile preparation and screening of a series of photothermal nanocoating layers via the metal ion (i.e. Cu(II),Fe(III), Ni(II), Zn(II)) promoted in situ polymerization of typical phenolic moieties of tea polyphenols (i.e., catechol and pyrogallol). It was found that those resulting metal-polyphenolic nanocoatings showed various promising features, such as high blackness and strong adhesion, excellent and tunable light absorption properties, good hydrophilicity and long-term stability. We further fabricated the photothermal composite devices by in situ formation of metal-polyphenolic nanocoatings on pristine silks for solar desalination, which demonstrated promising durable evaporation behaviors with excellent evaporation rates and steam generation efficiencies. We believe that this work could provide more opportunities towards new types of bio-inspired and sustainable photothermal nanomaterials for solar energy harvesting applications such as water desalination.
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高影响因子
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
·
2022
·Vol. 194
·期 11
·4999-5016
·
IF 3.094
Ma Teng,Kong Weixi,Liu Yunting,Zhao Hao,Ouyang Yaping,Gao Jing,Zhou Liya,Jiang Yanjun
The application of immobilized enzymes in pharmaceutical and bulk chemical production has been shown to be economically viable. We demonstrate the exceptional performance of a method that immobilizes the old yellow enzyme YqjM and glucose dehydrogenase (GDH) on resin for the asymmetric hydrogenation (AH) of C = C bonds in a SpinChem reactor. When immobilized YqjM and GDH are reused 10 times, the conversion of 2-methylcyclopentenone could reach 78%. Which is because the rotor of the SpinChem reactor effectively reduces catalyst damage caused by shear force in the reaction system. When the substrate concentration is 175 mM, an 87% conversion of 2-methylcyclopentenone is obtained. The method is also observed to perform well for the AH of C = C bonds in other unsaturated carbonyl compounds with the SpinChem reactor. Thus, this method has great potential for application in the enzymatic production of chiral compounds.
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高影响因子
Science China-Materials
·
2023
·Vol. 66
·期 6
·2192-2198
·
IF 8.1
Chen Shaojie,Hu Xiangchen,Nie Lu,Yu Yi,Liu Wei
Solid-state lithium metal batteries (SSLMBs) have attracted a lot of interest owing to their high safety and high energy density potential. However, the growth of lithium dendrite in solid electrolytes still hinders practical applications of SSLMBs. In this study, we develop a simple heat treatment method for reviving and recycling garnet oxide electrolytes with Li dendrite penetration. Interestingly, the recovered garnet electrolyte exhibits higher relative density, enhanced ionic conductivity and improved critical current density compared with the pristine one. The thermal healing is due to the products of the reaction between dendritic Li metal and air that contribute to the further densification of garnet electrolytes during heat treatment. This work demonstrates a new way to recycle garnet electrolytes, which may further extend to other various solid electrolytes.
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高影响因子
JOURNAL OF NANOPARTICLE RESEARCH
·
2022
·Vol. 24
·期 4
·1-15
·
IF 2.533
Wang Zhentao,Hasan Jaafar,Wang Jingjing,Zhang Caiwei,Iqbal Waheed,Chang Ninghui,Qin Chuanguang
The treatment of dye-bearing wastes by adsorption using low-cost synthetic adsorbents is urgently needed and challenging because it offers the dual benefit of water treatment and waste management. Herein, the flower-like MoS 2 /g-C 3 N 4 nanocomposites with a size range of 200–400 nm and a specific surface area of 70.656 m2/g were synthesized as new methylene blue (MB) adsorbent materials. Their adsorption mechanisms and influences of pH, adsorbent dosage, concentration, and temperature on the adsorption properties were investigated by batch sorption experiments. Adsorption isotherm data were fitted with the Langmuir model, and the adsorption kinetic characteristics conform to the quasi second-order kinetic equation. According to thermodynamic data, methylene blue (MB) adsorption was endothermic and spontaneous, exhibiting a maximum adsorption capacity of 278.4 mg/g at 45 °C. Additionally, the impact of MB effluent on the germination of chickpea and wheat was studied contrastively with treatment of the tested materials. The results indicated that adequate adsorption of flower-like MoS 2 /g-C 3 N 4 nanocomposite could potentially treat wastewater from the textile industry to be used for irrigation and solve the problem of textile effluent disposal. Graphical abstract
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高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2020
·Vol. 325
·期 2
·453-462
·
IF 1.137
Lu Shichao,Chang Shuquan,Li Zheng,Zhang Xiaohong,Hu Xiaodan,Zhang Haiqian
Magnetic Au/Fe 3 O 4 /poly(styrene-sodium styrene sulphonate) composite microspheres (Au/Fe 3 O 4 /P(St-NaSS) CMs) were successfully prepared via a gamma-radiation method. Au and Fe 3 O 4 were formed at the same time under irradiation and well dispersed on uniform P(St-NaSS) microspheres. The as-prepared CMs exhibit good catalytic properties and recyclable performances for the catalytic reduction of 4-nitrophenol (4-NP). The kinetic rate constants are 8.75 × 10 −3 s −1 and 7.71 × 10 −3 s −1 for two samples, respectively. The conversion rate of 4-NP can keep about 95% with catalysts after five cycles. They exhibit good magnetic behavior and have saturation magnetization value of about 9 emu g −1 , which can be easily separated from the solution under external magnetic field. This strategy is efficient and facile, which can be extended to fabricate other CMs.
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高影响因子
CELLULOSE
·
2021
·Vol. 29
·期 1
·605-617
·
IF 5.044
Gao Shan,Li Hongqiang,Guan Hang,Zheng Longzhu,Lai Xuejun,Chen Wanjuan,Zeng Xingrong
The inherent hydrophilicity, flammability and electrical insulation of pristine cotton fabric (CF) severely restrict their applications in many traditional fields including tents, umbrellas and outdoor jackets and some emerging fields such as wearable electronics. Herein, we report a facile approach to fabricate multifunctional CF with superhydrophobicity, flame-retardancy and electrical conductivity via layer-by-layer assembly and spray-coating. Specifically, the pristine CF was alternately covered with branched polyethyleneimine modified halloysite nanotubes (P-HNTs) and phytic acid (PA), followed by a sprayed layer of octadecylamine modified carboxylated carbon nanotube (CNT-ODA)/polydimethylsiloxane (PDMS) hybrid coating. The obtained multifunctional CF exhibited superhydrophobicity with a high water contact angle (WCA) of 162° and excellent surface stability. Owing to the physical barrier roles of the HNT layer, intumescent char layer by the N-P synergy of b-PEI and PA and the CNT/Si–C compounds after the pyrolysis of the outer CNT-ODA/PDMS layer, the SFRC-CF exhibited good thermal stability and outstanding flame-retardant performance. Furthermore, the SFRC-CF based piezoresistive pressure sensor had the advantages of stable resistance signal and good repeatability, and was successfully applied for detecting different human behavior even under wet environment. Our findings conceivably stand out as a new methodology to fabricate multifunctional cotton fabrics for practical applications in the fields of wearable devices and flexible electronics. Graphic abstract
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高影响因子
危险品化学品经营许可证（带存储）