TALANTA
·
2018
·
IF 4.244
Yue Wang,Xue Li,Geoffrey I.N. Waterhouse,Yunlei Zhou,Huanshun Yin,Shiyun Ai
In this work, a novel and sensitive photoelectrochemical (PEC) strategy was designed for protein kinase A (PKA) detection, comprising carbon microsphere (CMS) modified ITO electrode, TiO 2 as the phosphate group recognition material and graphite-carbon nitride (g-C 3 N 4 ) as photoactive material. For the first time, gold nanoparticle decorated zeolitic imidazolate frameworks (Au-ZIF-8) was employed to fabricate biosensor for PKA activity assay with the function of substrate peptide immobilization and signal amplification. Firstly, substrate peptides were assembled on the Au-ZIF-8/CMS/ITO surface through the covalent bonding between the gold nanoparticles (AuNPs) and sulfydryl groups of the peptides. Then, in the presence of ATP , phosphorylation of the substrate peptide was achieved under PKA catalysis. Finally, TiO 2 -g-C 3 N 4 composites were further modified on the electrode surface based on bonding between TiO 2 and phosphate groups created via phosphorylation of the peptide (yielding TiO 2 -g-C 3 N 4 /P-peptide/Au-ZIF-8/CMS/ITO), which is different with our previous work by directly immobilizing g-C 3 N 4 composite on electrode surface. The developed method showed a wide linear range from 0.05–50 U mL −1 . The detection limit was 0.02 U mL −1 (S/N = 3). The constructed biosensor exhibited high detection specificity for PKA. In addition, the wide applicability of this biosensor was demonstrated by evaluating the inhibition ability of ellagic acid towards PKA.
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高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2018
·
IF 5.091
Jirong Bai,Chaochuang Yin,Haiyang Xu,Gang Chen,Zhijiang Ni,Zhilei Wang,Yaguang Li,Shifei Kang,Zheng Zheng,Xi Li
Hydrogen generation photocatalyzed by low-cost graphite carbon nitride (g-C 3 N 4 ) is a fascinating and effective route to solve energy crisis, but is mainly limited by the few reactive sites, low carrier separation efficiency and mediocre visible-light utilization. In this work, these limitations were tackled through a facile eco-friendly precursor pretreatment by tuning bulk g-C 3 N 4 into porous structure. This pretreatment restricted agglomeration in the subsequent condensation and created more porous channels for charge carrier transfer and more surface active sites for reaction. The modified g-C 3 N 4 has larger surface area, broader visible-light response, enhanced electron migration capacity and prolonged lifetime of photogenerated carriers. These well-amended g-C 3 N 4 nanosheets possess an average hydrogen evolution rate 5.7 times that of bulk g-C 3 N 4 . This work affords a facile, eco-friendly and scalable strategy to design or synthesize other porous materials.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2018
·
IF 5.091
Xinxin Liu,Minmin Chang,Bei He,Ling Meng,Xiaohui Wang,Runcang Sun,Junli Ren,Fangong Kong
High strength hydrogels open new possibilities in the fields of bioengineering and biomedical. In this paper, a highly efficient one-pot strategy was developed to prepare carboxymethyl xylan-g-poly (acrylic acid) (CMX-g-PAA) hydrogels with high compression strength, high elongation and high elasticity by using the metal coordination and the reinforcement of hydroxylate multi-walled carbon nanotubes (HCNTs). Prepared hydrogels were characterized by means of FTIR, XRD, SEM, rheological measurements as well as their swelling and mechanical properties. Results showed that the Fe 3+ -carboxyl coordination and HCNTs imparted hydrogels with high strength and good rapid recovery properties, in which the maximum high compressive strength and elongation at break were achieved to 10.4 MPa and 1032%, and the shape of hydrogels almost returned to the original shape after the external force was removed after 30 cycles of compression. These hydrogels also exhibited Fe 3+ -triggered shape memory properties. Therefore, as-prepared hydrogels possessing high strength, rapid recovery and shape memory properties, could broaden access for application in intelligent toys, electronic skin, biosensing, and tissue engineering.
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高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2018
·
IF 11.698
Zhi Zhu,Xu Tang,Tianshuai Wang,Wenqian Fan,Zhi Liu,Chunxiang Li,Pengwei Huo,Yongsheng Yan
Developing low-cost and high-efficiency g-C 3 N 4 (CN) semiconductor with modification has been proved to possess the potential advantage for environmental remediation in recent years. Herein, element doping of CN framework was found significantly on controlling its electronic structure. The new two-dimensional photocatalyst of Co-doped CN (Co-CN) applicable in photocatalytic reactions for 2-Mercaptobenzothiazole degradation was designed and synthesized. It was for the first time revealed that the Co-N bonding could lead to enhance significantly photoelectric properties, the rate for electron-hole pairs separation and photocatalytic activity in comparison with bulk CN. The characterization and density functional theory (DFT) results insight into the reason that the 3d electrons of the doped Co has excellent contribution to adjust the band gap of Co-CN. The present work provide a broadening window for Metal-doped CN with outstanding performance.
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高影响因子
Energy Technology
·
2018
·Vol. 7
·期 8
·1800846
·
IF 3.175
Sibo Chen,Siyuan Yang,Xiaolin Sun,Kelin He,Yun Hau Ng,Xin Cai,Wuyi Zhou,Yueping Fang,Shengsen Zhang
The photocatalytic H 2 evolution is an important technology to solve the energy crisis. The hydrogen evolution rate of the graphite carbon nitride (g-C 3 N 4 ) system in triethanolamine solution as sacrificial agent is clearly higher than that in methanol solution. But up to now, most of the Cu nanoparticles as cocatalyst of g-C 3 N 4 photocatalytic systems for hydrogen evolution are performed in methanol solution because Cu nanoparticles are unstable in triethanolamine solution. Here, carbon-coated Cu nanoparticles as a cocatalyst of g-C 3 N 4 composites (Cu@C/g-C 3 N 4 ) are prepared by a simple two-step technology that includes annealing followed by grinding. The compositions, morphology, and optical and photoelectrochemical properties of the composites are characterized by means of physicochemical techniques. The prepared composition is used to generate hydrogen under visible-light irradiation in triethanolamine solution. The results show that the hydrogen evolution rate of the optimal Cu@C/g-C 3 N 4 is up to 265.1 μmol g −1 h −1 , which is close to the activity of 0.5% Pt/g-C 3 N 4 , and after four repeated reactions, the photocatalytic activity decreases only by ≈15%. The good photocatalytic activity and stability result from Cu nanoparticles increase the transfer efficiency of charge carriers by trapping the photogenerated electrons produced by g-C 3 N 4 and the protective effect of carbon layer on Cu nanoparticles.
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APPLIED CATALYSIS B-ENVIRONMENTAL
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2018
·
IF 11.698
Yabin Jiang,Zongzhao Sun,Chao Tang,Yuxia Zhou,Lei Zeng,Limin Huang
Porous structure, nitrogen defects and oxygen dopants are simultaneously introduced into the framework of graphitic carbon nitride (g-C 3 N 4 ) by a simple co-pyrolysis of dicyandiamide and ammonium persulphate ((NH 4 ) 2 S 2 O 8 ). The (NH 4 ) 2 S 2 O 8 plays multi-function roles in the co-pyrolysis process. It not only restrains polycondensation to generate nitrogen defects but also introduces porous structure and oxygen dopants due to its strong oxidative ability. The synergetic effect of the nitrogen defects and oxygen dopants leads to the change of π band state and LP state (lone pair electrons), causing the change of electron transition in the modified g-C 3 N 4 . The transitions from impurity levels play a predominant role in excitation process while the transition from intrinsic HOMO to LUMO becomes subordinate, which improve the charge separation significantly. The modified g-C 3 N 4 exhibits excellent photocatalytic hydrogen evolution activity under visible light illumination, which is almost 6 times higher than pristine g-C 3 N 4 because of the improved efficiency of charge separation and increased specific surface area. These findings provide a simple and efficient method to improve the photocatalytic activity of g-C 3 N 4 by changing the electron transition through a rational band structure engineering.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2018
·
IF 3.909
Lin Shao,Yang Cao,Zhanying Li,Wenbin Hu,Shize Li,Lingbin Lu
Alginate was grafted with NIPAM and NHMAM successfully, and a new responsive copolymer, alginate-g-P(NIPAM-co-NHMAM), was obtained. A novel dual responsive polysaccharide-based aerogel with thermo/pH sensitive properties was designed from the copolymer as drug controlled release system. The chemical structure of the copolymer was characterized by FT-IR and 1 H NMR. Lower critical solution temperature (LCST) of the copolymer covered a wide temperature range from 27.6 °C to 42.2 °C, which could be adjusted with changing the ratio between NIPAM and NHMAM. The dual responsive aerogel had a three-dimensional network structure. As a drug controlled release system, the aerogel was high responsive to both temperature and pH with drug loading efficiency up to 13.24%. Above LCST, the aerogel had a faster drug release, and drug was completely released in neutral environment, while the drug release was obstructed in acid environment. Furthermore, the drug release mechanism of the aerogel was illuminated. These results indicated that the dual responsive aerogel was a promising candidate for drug carriers.
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高影响因子
RSC Advances
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2014
·Vol. 4
·期 106
·61759-61766
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IF 3.708
Hongmei Chen,Xingrong Tan,Juanjuan Zhang,Qiyi Lu,Xin Ou,Yuan Ruo,Shihong Chen
In this article, a new electrochemiluminescent (ECL) biosensor based on a g-C3N4–hemin nanocomposite and hollow gold nanoparticles (HGNPs) was constructed to detect lactate. Firstly, the g-C3N4 nanosheets were prepared through ultrasonication-assisted liquid exfoliation of bulk g-C3N4, which was obtained through polymerizing melamine under 600 °C. Then, the nanocomposites of g-C3N4 nanosheets and hemin were prepared to modify a glassy carbon electrode. Subsequently, HGNPs were self-assembled onto the electrode for adsorbing lactate oxidase to achieve a lactate biosensor. Due to the excellent catalytic effect of g-C3N4–hemin and HGNPs on the luminol/H2O2 ECL system, the as-prepared biosensor exhibited a good response performance to lactate with a linear range of 1.7 × 10−8 to 5.0 × 10−4 M and a detection limit of 5.5 × 10−9 M. In addition, the prepared ECL biosensor exhibited satisfying reproducibility and stability. The g-C3N4–hemin nanocomposite might have great potential application in a luminol/H2O2 ECL system.
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JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
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2015
·Vol. 91
·期 5
·1378-1386
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IF 2.349
Qiujin Jia,Dongping Li,Xuechuan Gao,Jilong Yan,Qinglin Ma,Fanjun Meng
BACKGROUND Although methyl acrylate has been graft polymerized from cellulose and functionalized with hydrazine and hydroxylamine for removal of copper and nickel ions, the adsorption capacity was less than 80 mg g −1 . The present work reported hydrazinolysis of cellulose-graft-polymethyl acrylate and remarkably improved adsorption capacity for Cu(II) and Ni(II) in aqueous solution. RESULTS Hydrazinolyzed cellulose-graft-polymethyl acrylate (Cell-g-PMA-HZ) has been prepared by ceric salt-initiated graft polymerization of methyl acrylate from microcrystalline cellulose surface and subsequent hydrazinolysis with hydrazine hydrate. The successful synthesis was confirmed by Fourier-transform infrared spectroscopy, 13 C-NMR, elemental analysis, scanning electron microscopy and thermogravimetric analysis. Adsorption behavior of Cell-g-PMA-HZ for Cu(II) and Ni(II) were studied through batch static adsorption processes and column chromatography methods. The influences of graft yield, initial pH, contact time and temperature on adsorption capacity of Cell-g-PMA-HZ as well as adsorption equilibrium, kinetic and thermodynamic properties were studied in detail. Kinetic adsorption can be explained by pseudo-second-order and adsorption isotherms fitted with Langmuir isotherm model, from which maximum equilibrium adsorption capacity can be derived as 229.36 mg g −1 for Cu(II) and 173.91mg g −1 for Ni(II) at 28°C. Further thermodynamic investigation indicated that adsorption of Cu(II) and Ni(II) by adsorbent Cell-g-PMA-HZ was exothermic and spontaneous under the studied conditions. CONCLUSIONS Hydrazinolysis of cellulose-graft-polymethyl acrylate has been accomplished. As an adsorbent, the prepared Cell-g-PMA-HZ was reusable and fairly efficient for removal of Cu(II) and Ni(II) from aqueous solution. © 2015 Society of Chemical Industry
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Journal of Materials Chemistry B
·
2015
·Vol. 3
·期 27
·5478-5489
·
IF 4.726
Yong Sun,Yaning Wang,Yani Cui,Wen Zou,Yanfei Tan,Jie Liang,Yujiang Fan,Xingdong Zhang
Stimuli-responsive targeted polymeric micelles as drug delivery systems have recently attracted significant attention for the treatment of various cancers, which could improve delivery efficiency by tumor-specific recognition via active targeting strategies. In this research, DOX-incorporated bioreducible polymeric micelles based on PAA-g-PEG/PEG–Fa conjugated polymers were prepared and characterized as nanocarriers for promoting intracellular anti-tumor drug delivery efficiency via folate receptor-mediated endocytosis. The anti-proliferative activity on cancer cells, biodistribution, active-/passive-targeting efficiency, tumor growth inhibition efficiency, and biological toxicity were evaluated in vitro and in vivo. The MTT assay demonstrated that the DOX-encapsulated active-targeting PAA-g-PEG/PEG–Fa micelles had much greater growth inhibition effect against 4T1 and KB than passive-targeting micelles. These active-targeting micelles showed superior tumor accumulation and excellent tumor growth inhibition effect as revealed by the fluorescence optical imaging technique and tumor volume change investigation, as well as the survival study of the tumor-bearing Balb/c mice. Furthermore, the active targeting micelles greatly decreased the toxicity of DOX on the heart and other organs. These potential results encouraged us to further optimize the molecular structure to achieve more excellent targeted therapeutic effect.
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JOURNAL OF APPLIED POLYMER SCIENCE
·
2015
·Vol. 132
·期 44
·
IF 1.768
Li-Feng Fang,Ming-Yong Zhou,Na-Chuan Wang,Bao-Ku Zhu,Li-Ping Zhu
To improve the antifouling property of poly(vinyl chloride) (PVC) membranes, a series of poly(methacrylic acid) grafted PVC copolymers (PVC -g- PMAA) with different grafting degree were synthesized via one-step atom transfer radical polymerization process utilizing the labile chlorines on PVC backbones followed by one-step hydrolysis reaction. PVC/PVC -g- PMAA blend membranes with different grafting degree and copolymer content were prepared by nonsolvent induced phase separation method. The surface chemical composition, surface charge, membrane structures, wettability, permeability, separation performances and the fouling resistance of blend membranes were carefully investigated. The results indicated that the PMAA chains were segregated towards the surface and the membranes were endowed with negative charge. The hydrophilicity and permeability of the blend membranes were obviously improved. Furthermore, the antifouling ability especially at neutral or alkaline environments was also significantly increased. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132 , 42745.
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Analytical Methods
·
2015
·Vol. 7
·期 21
·9340-9346
·
IF 1.821
Kewei Wang,Na Sun,Xinpan Li,Ruihua Zhang,Guangyue Zu,Jine Wang,Renjun Pei
This study reported the development of a p–n heterojunction photoelectrochemical biosensor using a G-quadruplex as the recognition system. The n-type ZnO nanorods and p-type BiOI nanoflakes were combined to form the heterostructure by in situ growth of BiOI attributed to a simple impregnating-hydroxylation method. This simple p–n heterojunction fabrication method could facilitate the development of rapid and sensitive visible light activated PEC sensors. In this study, the ZnO/BiOI photoelectrode showed a rapid photocurrent decrease in the presence of Pb2+ due to the electron withdrawing effect of hemin which bound with the G-quadruplex/Pb2+ complex. This PEC biosensor exhibited a good response following the concentration of Pb2+ in the range from 10 to 100 μM.
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