Biosensors-Basel
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2024
·Vol. 15
·期 1
·9
·
IF 4.9
Changyun Quan,Yue Zhang,Yuanyuan Liu,Liping Wen,Haixia Yang,Xueqin Huang,Minghui Yang,Binjie Xu
Electrochemical glucose sensor holds significant promise for the monitoring of blood glucose levels in diabetic patients. In this study, we proposed a novel electrochemical glucose sensor based on 1,10-Phenanthroline-5,6-dione (PD)/Ru(III) as a dual redox mediator. The synergistic effect of PD and Ru(III) was utilized to efficiently facilitate the electron transfer between the enzyme-active center and the electrode. Then, a commercial disposable electrochemical glucose sensor was constructed based on screen-printing electrodes. Experimental results indicated the synergy between PD and Ru(III) provided a promising electron transfer environment for a glucose dehydrogenase (GDH)-catalyzed glucose reaction. The sensor exhibits a linear glucose response range from 0.01 to 38.6 µmol/L, with a limit of detection (LOD) as low as 7.0 µmol/L and a sensitivity of 38 µA·L/(mmol·cm2). The accuracy of the sensor was further validated in spiked recovery tests of human venous blood samples. The glucose recovery rate was between 99.5% and 107%, with a relative standard deviation (RSD) of less than 3.2%. These results demonstrate that our sensor has high potential for commercialization and practical application in glucose monitoring.
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CHEMICAL ENGINEERING JOURNAL
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2024
·
IF 13.3
Weikang Ling,Jiliang Ma,Min Hong,Runcang Sun
Photocatalytic CO 2 reduction and biomass selective oxidation have considerable practical implications in addressing environmental challenges. However, developing efficient photocatalyst is the key to realize the mass-market applications. Herein, an MoS 2 @GCN S-scheme heterojunction, rich in sulfur vacancies (Sv), was fabricated by a dicyandiamide-blowing and calcination strategy using NH 4 Cl as the gas template. With the synergistic effects of Sv and the S-scheme charge migration mechanism, the 30%-Sv-MoS 2 @GCN demonstrated exceptional performance, showcasing a CO evolution rate of 68.3 μmol g −1 h −1 and a xylonic acid yield of 64.2%, without using any sacrificial agents. The formation of Sv was confirmed through electron paramagnetic resonance (EPR) analysis. The S-scheme charge transfer mechanism of the Sv-MoS 2 @GCN heterojunction was verified by in-situ X-ray photoelectron spectroscopy (XPS) spectra, EPR analysis, and density functional theory (DFT) calculations. This study establishes a framework for enhancing photocatalytic CO 2 reduction and biomass selective oxidation by regulating charge transfer through sensible structural design.
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ChemistrySelect
·
2024
·Vol. 9
·期 40
·e202402030
·
IF 1.9
Wei Tang,Haojie Qian,Xinyue Wang,Caoxing Huang
Graphical The solid acid catalysts were triumphantly prepared using the residues of poplar sawdust's enzymatic hydrolysis, which displayed the most acidic sites and high catalytic activity, and achieved the highest furfural yield and furfural selectivity during xylose conversion. The utilization of biomass as a carbon source for the synthesis of renewable solid acid catalysts (SA) has emerged as a prominent research direction in the field of heterogeneous catalysis. Based on the challenges associated with reusing residues from lignocellulosic biorefining, the biomass-based SA (BCSA) were prepared using poplar sawdust (PS), hydrothermally pretreated PS (PPS), and the residue of PPS's enzymatic hydrolysis (ER). The characterization revealed that all three types of BCSA were loaded with catalytic groups, and the BCSA synthesized using ER rich in lignin components exhibited a highly efficient catalytic structure. Furthermore, the catalysis of a 20 g/L xylose solution with BCSA-ER as SA also achieved the highest furfural yield (89.3%) and furfural selectivity (90.3%). The findings of this study suggested that lignin holds significant potential as a carbon carrier for SA, thereby offering a viable solution for utilizing by-products from lignocellulosic biorefining.
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FOOD CHEMISTRY
·
2025
·
IF 9.8
Pengfei Jiao,Xingmei He,Zhihao Zhou,Xuan Wang,Yunrui Zhang,Pin Chang,Xin Zhang,Peng Wang,Pengpeng Yang,Qiuhong Niu
s Extraction of bioactive substances from food processing waste is currently an important research topic. Ultrasonic and hyper-cross-linked resin in-situ adsorption method were proposed to synergistically assist in the extraction of phenolic antioxidants from hawthorn seeds using deep eutectic solvents (DESs). DES composed of choline chloride and oxalic acid outperforms other DESs in terms of extraction efficiency. The adsorption of non-polar resin XDA-1 increases the yield of polyphenols and flavonoids by 45.16 % and 3.61 times, respectively. The extraction kinetic curves conform to pseudo-second-order rate model. The extraction yield and rate using DES is markedly superior to that using conventional solvents. The components analyzed using UPLC-MS indicate that the phenolic compounds in extract are mainly ellagic acid, vanillin, hesperetin-7-O-β-D-glucopyranoside, and hesperidin, etc. The primary forces facilitating extraction are hydrogen bonding and van der Waals interactions found by the conductor-like screening model for real solvents calculation.
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FUEL
·
2024
·
IF 6.7
Guojun Liu,Shaoshuai Wang,Caiming Zhou,Qiang Zhao,Jiaxue Hu,Zhenzheng Gui,Yuhui Chen,Yong Huang,Peng Zhang,Fenfen Wang
Formic acid is a versatile and promising value-added chemical derived from the chemoselective transformation of renewable biomass resources. However, achieving a high production rate of formic acid remains a pivotal and enormous challenge. Herein, we synthesized a sequence of BiVO x catalysts based on vanadium-promotion by a facile and cost-effective strategy for selective oxidation of biomass-derived xylose in water under O 2 atmosphere. Particularly, the resultant Bi 1 V 2 O x exhibited a remarkably enhanced catalytic activity, higher selectivity toward formic acid, and excellent recyclability, giving a yield of 75.8 % and a production rate of formic acid (9.22 mol FA mol V −1 h −1 ) at 170 °C within only 20 min. Such pronounced improved performance was largely attributed to the synergistic effect between V and Bi species, with higher surface area, abundant surface acidity, as well as stronger adsorption energy, meanwhile efficiently suppressing the formation of undesired by-products. This study demonstrates that the promotion of V in BiVO x leads to more efficient catalytic oxidation of xylose to formic acid, and with further driven research that proved great potential for generating formic acid from renewable biomass resources for future industrial application.
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Nanomaterials
·
2024
·Vol. 14
·期 23
·1887
·
IF 4.4
Xiaolong Qiao,Shixing Wang,Qiulian Liu,Yuanming Zhang,Guangting Han,Haoxi Ben,Wei Jiang,Haiguang Zhao,Yan Song
China is the country with the most abundant bamboo resources in the world. Using bamboo as a raw material for pulping and papermaking can save a lot of wood and protect forests. Bamboo pulping enterprises mostly adopt sulfate processes to produce a large amount of black liquor (BL), which contains monosaccharides, polysaccharides, oligosaccharides, pectin, lignin, etc. The utilization of the high-value organic matter is of great economic and environmental significance. In this study, blue-green carbon dots (C-dots) were prepared from bamboo ( Lingnania chungii ) kraft pulp BL using a hydrothermal method. The changes in carbohydrate content in BL in relation to hydrothermal temperature and hydrothermal time were discussed in detail. Then, a series of characterizations of BL-C-dots, prepared under one of the hydrothermal conditions (180 °C, 6 h), were performed and the BL-C-dots showed an excitation-dependent photoluminescence (PL) spectrum and a quantum yield (QY) of 2.9% in an aqueous solution. Finally, the as-prepared BL-C-dots were successfully used as fluorescent materials to develop an anti-counterfeiting code. The fluorescent code exhibited a clear outline, an excitation-tunable color, good stability, and high security, showing great anti-counterfeiting potential and realizing the high-value utilization of BL.
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ANALYTICAL CHEMISTRY
·
2024
·
IF 6.7
Shen Jiang,Qiuyun Li,Guangrun Wu,Xuming Mu,Xiaotong Wang,Yunpeng Wang,Yanli Wu,Jing Wu,Yang Li
In the landscape of biomolecular detection, surface-enhanced Raman spectroscopy (SERS) confronts notable obstacles, particularly in the label-free detection of biomolecules, with glucose and other sugars presenting a quintessential challenge. This study heralds the development of a pioneering SERS substrate, ingeniously engineered through the self-assembly of nanoparticles of diverse sizes (Ag1@Ag2NPs). This configuration strategically induces ‘hot spots’ within the interstices of nanoparticles, markedly amplifying the detection signal. Rigorous experimental investigations affirm the platform’s rapidity, precision, and reproducibility, and the detection limit of this detection method is calculated to be 6.62 pM. Crucially, this methodology facilitates nondestructive glucose detection in simulated samples, including phosphate-buffered saline and urine. Integrating machine learning algorithms with simulated serum samples, the approach adeptly discriminates between hypoglycemic, normoglycemic, and hyperglycemic states. Moreover, the platform’s versatility extends to the detection and differentiation of monosaccharides, disaccharides, and methylated glycosides, underscoring its universality and specificity. Comparative Raman spectroscopic analysis of various carbohydrate structures elucidates the unique SERS characteristics pertinent to these molecules. This research signifies a major advance in nonchemical, label-free glucose determination with enhanced sensitivity via SERS, laying a new foundation for its application in precision medicine and advancing structural analysis in the sugar domain.
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MOLECULES
·
2024
·Vol. 29
·期 13
·3136
·
IF 4.2
Yupeng Ren,Jianhui An,Cheng Tian,Longchen Shang,Yexing Tao,Lingli Deng
Dihydromyricetin (DMY) has been encapsulated in delivery systems to address the solubility limitations of DMY in water and improve its bioavailability. Air-assisted electrospinning has been used as a novel technology to load DMY. To evaluate the impact of adding DMY to dextran/zein nanofibers and understand the effects of the Maillard reaction (MR) on the physical and functional properties of DMY-loaded nanofibers, dextran/zein/xylose nanofibers with 0%, 1%, 2%, 3%, and 4% DMY were fabricated, followed by MR crosslinking. Scanning electron microscopy (SEM) observations indicated that the addition of DMY and the MR did not affect the morphology of the nanofibers. X-ray diffraction (XRD) results indicated amorphous dispersion of DMY within the nanofibers and a decreased crystalline structure within the nanofibers following the MR, which might improve their molecular flexibility. The nanofibrous film formed after the MR exhibited both increased tensile strength and elastic modulus due to hydrogen bonding within the nanofibers and increased elongation at break attributed to the increased amorphization of the structure after crosslinking. The nanofibers were also found to exhibit improved heat stability after the MR. The antioxidant activity of the nanofibers indicated a dose-dependent effect of DMY on radical scavenging activity and reducing power. The maintenance of antioxidant activity of the nanofibers after the MR suggested heat stability of DMY during heat treatment. Overall, dextran/zein nanofibers with various DMY contents exhibited tunable physical properties and effective antioxidant activities, indicating that dextran/zein nanofibers offer a successful DMY delivery system, which can be further applied as an active package.
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ADVANCED FUNCTIONAL MATERIALS
·
2024
·
IF 18.5
Rong Ding,Yu-Pu Zhou,Yu-Chuan Zhang,Hao Chen,Fu-Rong Zeng,Yu-Tao Wang,Bo-Wen Liu,Yu-Zhong Wang,Hai-Bo Zhao
Carbon materials play a pivo tal role across various advanced applications, yet their synthesis traditionally necessitates inert atmospheres to avert oxidation at high temperatures, thus inflating production costs and resource utilization. Achieving precision synthesis of functional porous carbon materials via air-pyrolysis remains a formidable challenge. Herein, a streamlined, one-step lava-like carbonization approach is introduced enabling the fabrication of porous carbons boasting tailored morphologies (0-3D), elevated specific surface areas (540.7–1047.6 m 2 g⁻¹), heteroatom doping, and commendable carbon yields (20-39.1%) through direct pyrolysis within an air environment. Leveraging recyclable boric acid as a reaction medium, a lava-like flowing protective barrier above 170 °C is engendered that spontaneously creates an oxygen-free-like milieu devoid of high pressure or intricate procedures. This boron-containing lava serves dually as a template and chemical activator, facilitating pore formation and catalyzing porous carbon production. Notably, the method accommodates a spectrum of carbon sources, encompassing sugars, proteins, graphene oxide, and their metal mixtures. The resultant morphologically customizable carbons exhibit excellent performance in areas as diverse as microwave absorption and electrocatalysis. This work pioneers a novel pathway for large-scale precision synthesis of high-quality carbon materials via air-pyrolysis under mild conditions.
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JOURNAL OF CHROMATOGRAPHY A
·
2024
·
IF 3.8
Zhen Yao,Kehan Zhu,Tianyi Gu,Oliver J. Schmitz,Duxin Li
Polysaccharides have unique physio-chemical properties and various biological functions and have rapidly expanded interest over the last two decades. The purification of polysaccharides and their degraded oligosaccharides is challenging because carbohydrates have no chromophore and need a proper detector to monitor the chromatographic elution process. This study proposed an active derivatization detection (ADD) method based on active splitting from post-column flow, a microchannel reactor for efficient derivatization of polysaccharide reducing sugars with p-hydroxybenzoic acid hydrazide, and in-line detection by the UV detector of liquid chromatography system. The method and device were validated by the use of 11 monosaccharides, sulfated oligosaccharides (from degraded carrageenan), and polysaccharides (from Zizania latifolia ). It has shown much better performance than the traditional phenol-sulfuric acid method (gold standard). Moreover, the ADD module presumes an add-in to the original preparative LC system, independent of the scale of the purification process and type of system. The developed method is versatile for chromatographic separation of carbohydrates and lays the foundation for their subsequent studies.
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BIORESOURCE TECHNOLOGY
·
2012
·
IF 4.98
Weina Liu,Yucui Hou,Weize Wu,Muge Niu,Wenhua Wang
Efficient pretreatment is important for complete enzymatic conversion of lignocellulosic materials. Pretreatment of wheat straw with sulfur dioxide (SO 2 ) dissolved in hot water achieved xylose and total product yields of up to 61.1% and 93.9%, respectively, based on the mass of lignocellulose in wheat straw. The apparent activation energies for hemicellulose conversion and xylose dehydration were 7.8 and 9.0 kJ/mol. FT-IR spectra of the residual solid after treatment showed that the hemicellulosic components were converted, the hydrogen bonds in cellulose were broken, but the lignin structure was not changed. Importantly, the SO 2 was recovered from the product mixture by steam stripping and could be reused. Thus, the SO 2 –H 2 O system is an efficient and environmentally friendly way for the conversion of hemicellulose in wheat straw into monosaccharides, such as xylose, glucose and arabinose.
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ENERGY & FUELS
·
2012
·
IF 2.721
Junhua Zhang,Lu Lin,Shijie Liu
We present here the results of an investigation aimed at identifying catalysts for the dehydration of glucose and xylose to 5-hydroxymethylfurfural (HMF) and furfural in a diphasic reaction system, and the subsequent conversion of HMF and furfural to 2,5-dimethylfuran (DMF) and 2-methyl furan (MF) was also investigated. For the dehydration of glucose and xylose mixture, a series of SO42–/ZrO2–TiO2 solid acid catalysts were prepared by precipitation and impregnation method. Effects of various reaction parameters and catalyst reuse cycle toward the reaction performance were studied. Experimental results indicated that the product yield could reach 30.9 mol % (for HMF) and 54.3 mol % (for furfural) under the optimal experimental conditions. The SO42–/ZrO2–TiO2 catalyst is recoverable from the resulting product mixture and reused multiple times after calcination without any substantial change on the HMF and furfural yield. Furthermore, effects of various hydrogenation parameters of HMF and furfural in n-butanol promoted by carbon-supported ruthenium (Ru/C) were discussed, and the highest yield could reach 60.3 mol % (for DMF) and 61.9 mol % (for MF) under the optimal experimental conditions by starting with HMF and furfural in pure n-butanol, but the target products of DMF and MF could not be detected when directly used by the separated organic phase as solvent and substrate. However, the DMF and MF yield could reach 32.7 and 17.5 mol %, respectively, when the separated organic phase undergoes a further purification, which indicated that the purification of the organic phase is a key step for the further hydrogenation of HMF and furfural to DMF and MF.
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