ACS Applied Bio Materials
·
2026
·Vol. 9
·期 15
·6927-6940
·
IF 5.6
Peng Haorui,Zhang Yulin,Dai Qiyuan,Ding Yilin,Chen Hexuan,Zhang Shuai,Luo Huitong,Cao Xiaodong
The management of bone injuries arising from traumatic or pathological origins necessitates biomaterial platforms that bridge immediate hemorrhage control and long-term osteogenic guidance within a single implantable system. In this study, we fabricated a chitosan-based composite cryogel (CMS-BG/BMP2) using dual-template mesoporous bioactive glass (dMBG). By using the double-template agent method, we enhanced the specific surface area of bioactive glass, optimized its pore architecture, improved the loading efficiency of bone morphogenetic protein 2 (BMP2), and achieved its controlled release, thereby circumventing the adverse effects caused by excessive local concentration of BMP2. The cryogel exhibited over 20 kPa compressive strength, favorable cyclic compression resistance, and controlled degradation (∼50% mass loss in 28 days). Hemocompatibility assays confirmed its safety, while dMBG incorporation enhanced blood cell adhesion and hemostatic efficacy without compromising biocompatibility. In vitro tests showed that the composite promoted mice bone marrow mesenchymal stem cells (BMSCs) migration and osteogenic differentiation by upregulating ALP activity, calcium nodule formation, and osteogenesis-related genes. This multifunctional material integrates hemostasis, structural support, and bioactivity, offering great potential for the clinical treatment of hemorrhagic bone defects.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2026
·
IF 11.8
Yu-Ling Wang,Chen Chen,Jia-Yao Xu,Yu-Jie Jing,Bing Wang,Jing Zhang,Yan-Ming Liu,Jun-Tao Cao
Sensitive and accurate detection of tumor markers is crucial for disease diagnosis, yet numerous challenges still exist due to limitations of single-mode assays. This work constructed a universal dual-mode sensing platform combining closed bipolar electrode (cBPE) and split-type immunoassay, which realized simultaneous electrochemiluminescence (ECL) and electrochromic detection of proteins upon a single potential stimulus. Specifically, on the cBPE, L012 served as the ECL emitter at the anode, while Prussian blue (PB) film at the cathode acted as the electrochromic sensing unit. Applying a single potential stimulus could trigger simultaneous ECL emission and the color change from blue PB to white Prussian white. By virtue of MgO 2 @GOx-Ab 2 signal probes as bioprobe, a split-type immunoassay was developed for prostate-specific antigen (PSA) detection. The target-induced production of H 2 O 2 from cascade glucose oxidation and MgO 2 hydrolysis greatly enhanced the anodic ECL signal and facilitated the cathodic PB reduction. Consequently, the strategy achieved the highly sensitive and visual dual-mode assay for PSA, yielding the limits of detection of 2.7 × 10 −12 g/mL for ECL detection and 3.1 × 10 −9 g/mL for electrochromic sensing, respectively. The study opened up an avenue for developing simultaneous multi-mode sensing platforms toward more biomarkers.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 5
·124392
·
IF 7.5
Xinya Wang,Yongshuo Zhang,Zihao Li,Qi Wang,Wei Zhang,Yanjie Wu,Mingxing Chen
Janus membrane has been attracting more and more attention in field of oil-water separation, owing to its asymmetric wettability on opposite surfaces. Inspired by the special structure of lotus leaves and Setaria viridis, we successfully fabricated dual-bioinspired Janus nanofiber membranes via sequential electrospinning and low-temperature hydrothermal synthesis. The structure and performance were modulated by adjusting Zn(NO 3 ) 2 ·6H 2 O concentration and Zn(Ac) 2 ·2H 2 O addition amount. Specifically, with the Zn(NO 3 ) 2 ·6H 2 O concentration increasing from 0 g·L −1 to 22.2 g·L −1 , the diameter of ZnO NWs increased and the hydrophilic nanofiber layer became denser. When Zn(NO 3 ) 2 ·6H 2 O concentration was 14.8 g·L −1 , the hydrophilic nanofiber layer of obtained Janus nanofiber membrane exhibited excellent separation performance for oil-in-water emulsions with remarkable separation flux of 1957.68 L·m −2 ·h −1 and high separation efficiency of 98.53%. Moreover, the hydrophobic nanofiber layer showed relatively excellent separation performance for water-in-oil emulsions with remarkable separation flux of 1336.77 L·m −2 ·h −1 and high separation efficiency of 98.98%. Additionally, with Zn(Ac) 2 ·2H 2 O addition amount increasing from 0 wt% to 2.0 wt%, the growth density of ZnO NWs increased, while the diameter decreased slightly. Correspondingly, the separation flux and separation efficiency of hydrophilic nanofiber layer for oil-in-water emulsions increased with increase of Zn(Ac) 2 ·2H 2 O addition amount. Besides, the incorporation of ZnO NWs endowed the Janus nanofiber membranes with intrinsic antibacterial properties against both E. coli and S. aureus . Our study not only emphasized the tunability of Janus nanofiber membranes but also highlighted their dual functionality as effective option for effective oil-water separation and antibacterial barriers.
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2026
·
IF 6
Jun Yu,Xianwei Zhao,Yongjun Chen,Azhu Wang,Pei Li,Yuzhe Wang,Haining Chen,Huicong Liu,Hui Ye,Weiping Li
Ga-doped zinc oxide (GZO) has attracted considerable interest for applications in electronic transport owing to its superior electrical properties. In this study, we report a low-temperature (<100°C) aqueous open-system route for the in-situ synthesis of GZO powders. The efficient substitutional doping of Ga 3+ into the ZnO lattice is achieved via a formation, in-situ transformation and dissolution–reprecipitation pathway of ε-Zn(OH) 2 or ZnGa-layered double hydroxide (ZnGa-LDH) intermediates, which simultaneously endows the products with unique flower-like or bundle-like morphologies. Chemical equilibrium calculations and time-dependent experiments reveal that the ionic species Zn(NH 3 ) 4 2+ and Ga(OH) 4 - , formed in the aqueous solution under high ammonia concentration, serve as reactive monomers that facilitate the formation and transformation of the intermediate phases. Electrical measurements combined with UV-Vis-NIR, EPR, and PL spectroscopic analyses indicate that Ga doping introduces shallow donor-type defects alongside zinc vacancy-related acceptor defects into the ZnO lattice, narrowing the optical bandgap and enhancing the electrical conductivity of the resulting powders. The GZO powder with a nominal doping ratio of 5% exhibits the lowest resistivity (Surface resistivity measured by the four-probe method is 3.43 × 10 4 Ω/□). This work provides a new pathway for the controllable preparation of functional conductive oxide powders.
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
·
2026
·
IF 5.2
Wenzhi Zhou,Mingkun Wu,Yuelong Liang,Zhenghai Yang,Jindong Yang,Mengkui Tian
Constructing heterojunctions is an effective strategy to enhance charge carrier separation and photocatalytic performance. In this study, a Bi 4 O 5 Br 2 /InVO 4 S-scheme heterojunction composite was prepared by a solvothermal method. The physicochemical properties were thoroughly investigated using various characterization techniques. Visible-light degradation experiments of ciprofloxacin (CIP) showed that the optimal sample, 5% Bi 4 O 5 Br 2 /InVO 4 (BI-5), exhibited the highest degradation activity (92.77%) along with excellent cycling stability. The effects of different environmental factors on the degradation performance were also systematically studied. The enhanced activity is attributed to the synergistic effect of the S-scheme heterojunction and increased oxygen vacancies. The S-scheme charge transfer, driven by the IEF at the heterointerface, enables spatial separation of photogenerated electrons and holes while preserving strong redox potentials, with reductive electrons accumulating in Bi 4 O 5 Br 2 and oxidative holes remaining in InVO 4 . Meanwhile, the introduction of InVO 4 creates abundant oxygen vacancies. These vacancies act as electron capture centers to suppress bulk recombination, introduce in-gap states that facilitate interfacial charge transfer, and provide additional active sites for surface reactions. Consequently, the S-scheme junction and oxygen vacancies jointly promote the separation, migration, and surface utilization of charge carriers, leading to significantly improved photocatalytic performance.
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2026
·
IF 6
Shiqing Yu,Yong Zheng,Yuze Du,Xi Zhang,Kai Wang,Juncheng Yao,Guangyu Wang
Antireflective coatings (ARCs) with self-cleaning and antistatic functionalities were fabricated using the sol-gel method with a Ti-Zn modified SiO 2 sol. Chain-like Ti-Zn composites were incorporated into SiO 2 nanoparticles exhibiting a dual-size distribution, forming a cross-linked composite structure that enhanced coating hardness while maintaining high transmittance and imparting multifunctional properties. The effects of Ti-Zn sol content on the surface morphology, microstructure, optical performance, mechanical strength, and wettability of the coatings were systematically investigated. The resulting coatings exhibited a hardness of 3H, an adhesion rating of 5B, and a solar-weighted transmittance (T sw ) of 95.31% across the wavelength range of 380–1100 nm, significantly higher than that of bare K9 glass (91.38%). Moreover, the introduction of the Ti-Zn composite sol imparted superhydrophilic properties to the coating (water contact angle, WCA = 1.8°) and facilitated the formation of continuous conductive pathways, reducing the surface resistivity to 3.61 × 10 8 Ω/□. This effectively suppressed electrostatic charge accumulation, thereby mitigating dust deposition. Furthermore, the coating demonstrated excellent multifunctional performance. A self-cleaning efficiency of 97.10% was achieved with a negligible loss in T sw (0.03%), while the haze value remained below 2% during antifogging tests. Additionally, the dust deposition density was reduced to 40.48% of that of bare glass, confirming the enhanced anti-dust performance.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Yang Wu,Long Zhang,Hao-Ran Yang,Jiaqi Li,Yuzhen Hou,Chang-Shun Li,Bobo Shi,Meng Zhou,Wulin Shang,Weiqing Kong,Huan Xu,Gang Zhou,Jiefeng Gao,Hongwei Zhao
Inspired by biological strategies, we developed an environment-adaptive Janus metafabric via multiscale interfacial electrospinning and soft-template-assisted phase separation strategy. • The Cyphochilus scale cooling layer achieves outstanding solar reflectance (94.8%) and mid infrared emissivity (98.1%), the Photon-trapping thermal layer achieves high solar absorptivity (81.8%). • Gradient porous architecture promotes directional sweat transport for enhanced wearing comfort. To mitigate heat stress during outdoor activities, passive radiative cooling (PRC) has been recognized as promising candidate for personal thermal management (PTM). However, conventional single-layer cooling fabrics cannot meet dynamic environments and wearing comfort. Herein, inspired by the highly scattering porous scales of Cyphochilus beetles, we developed an environment-adaptive Janus metafabric (EAJM) composed of a Cyphochilus scale-inspired cooling (CSC) layer and a Photon-trapping thermal (PTT) layer via multiscale interfacial electrospinning and soft-template-assisted phase separation (ST-PS) strategy. The EAJM combines hydrophilic PAN/SiO 2 fibers and hydrophobic PLA/PPy fibers into a functional Janus architecture. The CSC layer achieves outstanding solar reflectance (94.8%) and mid-infrared emissivity (98.1%), whereas the PTT layer serves as an efficient photon-trapping absorber (81.8%). This asymmetric spectral modulation enables dual-mode thermal management beyond the capabilities of conventional single-layer cooling fabrics. In outdoor tests, EAJM achieved outstanding radiative cooling (∆T max = 7.2 °C) and photothermal performance (∆T max = 2.8 °C) compared with bare skin. Meanwhile, the net cooling and heating power reached 113.7 W m −2 and 363.1 W m −2 , respectively. Furthermore, the wettability and pore-size gradient of EAJM facilitate anisotropic capillary-driven moisture transport, enabling rapid sweat wicking and evaporation. This work offers a promising strategy for PTMM and next-generation smart wearable textiles. Download: Download high-res image (363KB) Download: Download full-size image
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2026
·
IF 9.2
Chong Zhang,Xinbao Li,Lei Chen,Gonggang Sun,Qi Wang
Liquid hydrogen is attractive for large-scale hydrogen storage and long-distance transport because of its high volumetric energy density. However, exothermic ortho-para hydrogen conversion at cryogenic temperature causes boil-off loss and requires efficient catalysts. Iron-based catalysts are widely used, but their practical application is limited by poor stability under water, oxygen, and impurity attack. Herein, Fe@SiO 2 core-shell catalysts with tunable shell thicknesses were prepared by precipitation combined with hydrolytic coating and evaluated at 77 K. An amorphous SiO 2 shell was uniformly formed on the iron-based particles without destroying the active phase. The optimized catalyst achieved an outlet para-H 2 content of 47.5% and remained stable over 120 h. The improved catalytic performance is attributed to the SiO 2 coating, which enhances the structural stability of the iron-based particles while retaining accessible mesoporous transport pathways. These pathways facilitate H 2 transport to the iron-based active phase while reducing its exposure to the external environment.
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2026
·
IF 6.1
Peng Zhao,Kai Liu,Yueyan Li,Xiaofang Ban,Yuheng Wu,Jiaqi Liu,Xiaohong Wu,Ziyi Cheng,Fan Wang,Shuo Li,Feng Lin,Huifang Tang,Qingnan Zhao
The excessive activation of sympathetic nerve is closely related to cardiovascular diseases (CVDs). In this study, we developed a novel MIL-100(Fe)@Ag surface-enhanced Raman scattering (SERS) substrate for the simultaneous and effective detection of plasma norepinephrine (NE) and adenosine—two pivotal sympathetic hormones. The microscopic morphology and crystal structure of the substrate were characterized using techniques such as transmission electron microscope (TEM) and X-ray diffraction (XRD). Mechanistically, the HOMO-LUMO energy levels of the detection molecules were calculated using Gaussian. The substrate realized a dual SERS enhancement mechanism through the synergistic effect of localized surface plasmon resonance and interfacial charge transfer. Consequently, the MIL-100(Fe)@Ag platform exhibited high-sensitivity quantitative detection capabilities for NE and adenosine: the detection limit for NE is 0.596 nmol/L; the detection limit for adenosine is 0.24 nmol/L. Crucially, when applied to patients with pheochromocytoma—a neuroendocrine tumor characterized by plasma catecholamine surges, this method achieved robust and stable detection of plasma NE. It offered comparable diagnostic accuracy to conventional mass spectrometry while significantly reducing analysis complexity. Therefore, this innovative strategy may hold great promise for the long-term, decentralized monitoring of sympathetic nerve activity in populations at risk for CVDs or related clinical disorders.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2026
·
IF 5.3
Simeng Shao,Yi Wu,Peng Yu,Xilin Wan,Hongmei Yang
Panax ginseng is widely utilized as a functional food ingredient. The steaming process is a critical treatment that profoundly alters the metabolic profiles and enhances the therapeutic properties of Panax ginseng . This study characterized ginsenosides, saccharides, and amino acids in eight ginseng samples using ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) and multivariate data analysis. A total of 224 ginsenosides were identified, with 128 compounds exclusively detected in black ginseng (BG). Quantitative analysis of 49 metabolites showed that BG was enriched in rare ginsenosides (e.g., Rg3, Rg5, and Rk1) and monosaccharides (glucose and fructose) but had lower levels of basic amino acids, particularly arginine. Partial least-squares discriminant analysis (PLS-DA) identified 10 key discriminative markers distinguishing BG from other varieties. Furthermore, desorption electrospray ionization mass spectrometry imaging (DESI-MSI) visualized the spatial distribution of these markers, revealing their preferential accumulation in the cambium and phloem tissues. These findings provide comprehensive insights into the phytochemical transformation of ginseng during mild thermal processing, facilitating the development of BG as a functional food ingredient and supporting quality control in the food industry.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF RARE EARTHS
·
2026
·
IF 9.6
Dan Wu,Yanni Lang,Junhao Li,Qiu Fu,Yugeng Wen,Dacheng Zhou,Yong Yang,Yongjin Li,Zhiguo Song,Jin Han,Jianbei Qiu
Upconversion luminescent materials can convert near-infrared excitation into higher-energy emissions, showing great potential in applications such as temperature sensing and optical anti-counterfeiting. However, it remains challenging to simultaneously achieve high thermal stability, sensitive temperature response, and circularly polarized luminescence within a single system. In this work, chiral Bi 4 O 5 Br 2 : Yb 3+ /Er 3+ nanosheets were synthesized via a hydrothermal method combined with chiral modification and pH regulation, and their structural and luminescent properties were systematically investigated. The results indicate that pH regulation during precursor synthesis facilitates the optimization of the Bi 4 O 5 Br 2 morphology and improves its crystallinity, thereby promoting a more ordered crystal growth process. Subsequently, chiral induction introduces local lattice distortion while suppressing defect formation. The synergistic effect of both helps to significantly enhance upconversion luminescence performance. Under variable-temperature conditions, the 849 nm near-infrared emission ( 4 I 9/2 - 4 I 15/2 ) exhibits negligible thermal quenching over the temperature range of 293−533 K, in sharp contrast to the thermally quenched behavior of visible emissions. Based on this feature, a fluorescence intensity ratio (FIR) thermometry strategy was established, achieving high sensitivity with an absolute sensitivity ( S a ) of 20.73%/K and a relative sensitivity ( S r ) of 3.45%/K. Furthermore, the material exhibits pronounced emission intensity differences under circularly polarized excitation and detection. This enables the construction of a polarization-color synergistically tunable luminescent anti-counterfeiting system. This work provides a new strategy for designing multifunctional upconversion materials that integrate optical thermometry and polarization-based anti-counterfeiting capabilities.
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2026
·
IF 7.8
Yang Yige,Lei Peng,Song Kaichao,Zhou Chuchu,Tang Rou,Li He,Hao Yumei,Tan Huajin,Tan Xiaochuan,Zhang Yujia,Mei Mei,Huang Hongdong,Wang Lulu,Li Zhenhua,Zheng Wensheng
Cisplatin-induced acute kidney injury (AKI) remains a serious clinical complication, with excessive reactive oxygen species (ROS) recognized as key contributors. The natural antioxidant epigallocatechin-3-gallate (EGCG) shows promise in mitigating oxidative stress–related damage. However, its clinical application is limited by poor stability and low renal bioavailability. To address this, we developed a biocompatible nanoplatform by encapsulating EGCG within mesoporous polydopamine nanoparticles (EGCG-MPDA). Ultrasmall nanoparticles (<10 nm or <20 kDa) undergo rapid glomerular filtration and renal clearance, limiting therapeutic retention. While uncoated MPDA nanoparticles (∼200 nm) are large enough to avoid renal filtration, their size renders them highly susceptible to opsonization and MPS sequestration. To address this MPS-mediated clearance, we coated MPDA with a preclinically used BSA shell to create EGCG-MPDA@BSA. The biocompatible BSA corona acts as a “stealth” layer to attenuate opsonization, reduce early hepatic sequestration, and enhance interactions with peritubular endothelial cells, promoting nanoparticle passage into injured tubular epithelial cells. In a murine cisplatin-induced AKI model, EGCG-MPDA@BSA exhibited significantly enhanced therapeutic efficacy compared to uncoated nanoparticles and free EGCG. Transcriptomic and biochemical analyses revealed that its superior therapeutic efficacy arises from the activation of the Nrf2/HO-1/GPX4 antioxidant pathway, thereby alleviating oxidative stress, inflammation, and tubular damage. Collectively, this work presents an albumin corona strategy that enables effective renal retention of large nanoparticles, offering a safe, translatable approach for localized AKI therapy.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）