Arabian Journal of Chemistry
·
2023
·
IF 6
Zhujuan Li,Shuliang Chen,Futing Zi,Xianzhi Hu,Yunlong Chen
A fast and efficient Au (I) recovery adsorption method from an actual leaching solution of Cu 2+ -en-S 2 O 3 2- is presented. Aminophosphonic acid derivatized polyacrylonitrile fibers (PAN-NP), prepared with triethylenetetramine and phosphoric acid by chemical grafting, were used as the adsorbent. The adsorbent was well characterized by FT-IR, SEM, TGA and XPS. The effects of contact time, pH, temperature, and Au (Ⅰ) concentration were also investigated. PAN-NP can rapidly capture Au(S 2 O 3 ) 2 3– (20 min) and has a maximum adsorption capacity of 14.68 kg/t. Compared with -SH modified, PAN-NP has better stability and without oxidized. The adsorption process was described based on the Langmuir isothermal model ( R 2 > 0.99). Thermodynamic parameters indicated that the adsorption of Au(S 2 O 3 ) 2 3– on PAN-NP was exothermic ( ΔH θ = −9.906 kJ/mol) and adsorption mechanism involved a collective effect resulting the anion exchange of Au(S 2 O 3 ) 2 3– with –RNH 3 + H 2 PO 3 - , electrostatic attraction between –RNH 3 + and Au(S 2 O 3 ) 2 3– and complexation of P = O with Au (Ⅰ). Besides, PAN-NP-Au can be effectively eluted by sodium sulfite. Importantly, in the Cu 2+ -en-S 2 O 3 2- actual leaching solution, the PAN-NP can efficiently recover Au (I) with an adsorption percentage of up to 97 % at a the solidliquid ratio of 1:50, thereby affording a satisfactory application result. This is a meaningful method for recovering Au (Ⅰ) from thiosulfate solution.
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BIOSENSORS & BIOELECTRONICS
·
2023
·
IF 12.6
Jun Wang,Jiawen Han,Juan Wang,Xujuan Lv,Daoqing Fan,Shaojun Dong
Versatile nanozymes with fascinating catalytic properties provide inspiring and effective options for biosensing and pharmaceutical analysis. Herein, we report the first nanozyme-based ratiometric fluorescent platform for cysteine (Cys) and bleomycin (BLM) detection by harnessing the cost-effective and “mix & act” G-quadruplex/Cu(II) (G4/Cu) metal-nanozyme with satisfactory peroxidase-like activity, which was fully proven by circular dichroism (CD), electron paramagnetic resonance (EPR) spectra and reactive oxygen species (ROS) scavenging experiments. Based on the catalytic oxidation of G4/Cu metal-nanozyme toward two fluorescent substrates (Amplex Ultrared, AU; Scopoletin , Sc) with opposite responses in the presence of H 2 O 2 , and the specific interaction between Cu 2+ and targets, we achieved the highly sensitive detection of Cys and BLM. Through recording the fluorescence changes of AU (emission at 590 nm, F590) and Sc (emission at 465 nm, F465), we obtained good linear relationships between ratiometric fluorescence values (F590/F465) and variable contents of targets, resulting in the competitive LODs of Cys (6.7 nM) and BLM (10 nM), respectively. Moreover, this platform presented high selectivity (without the need for masking agent) and acceptable performance in human serum samples. Furthermore, a library of DNA contrary logic pairs (CLPs) and multilevel concatenated circuits were fabricated based on the reverse dual-output of the above platform, enriching the building blocks of biocomputing. This work not only enlightened the design of affordable, “mix & act” type nanozyme-based ratiometric biosensors with high reliability, but also facilitated the pluralistic application of nucleic acid-templated nanozymes to innovative biocomputing.
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高影响因子
Metals
·
2021
·Vol. 11
·期 6
·919
·
IF 2.351
Feng Feng,Jiamei Liu,Mingxing Zhao,Lu Yu,Haixin Wang,Chunshan Lu,Qunfeng Zhang,Jia Zhao,Yanxia Sun,Jie Cen,Xiaonian Li
Gold as a precious metal resource has high recycling significance. However, the current extraction methods cannot achieve the both efficiency and environmental friendliness. In this paper, we propose a new gold leaching agent, which can leach gold under light condition by mixing iodoform (CHI3) with 1-butyl-3-methylimidazolium dicyanamide (BmimN(CN)2) ionic liquid. Under 25 °C and 13 W incandescent lamp irradiation, the leaching yield of gold can achieve 100 wt%, and the average leaching rate is 945 mg Au/(h·mol·CHI3) (18.9 times of that of the cyanidation method). Through the analysis of the results of radical inhibition experiment, UV-Vis and XPS, a possible leaching mechanism is proposed: the iodine radical generated by light oxidizes Au0to Au+, and then forms AuN(CN)2by coordinating with N(CN)2−. Subsequently, the ionic liquid and Au N(CN)2form a stable [Bmim]·[Au(N(CN)2)2] ion pair structure, further promoting the dissolution reaction. The leaching yield of gold can reach 81.9 wt% and 100 wt%, respectively, when applied to ore and waste electrical and electronic equipment (WEEE); the leaching yield of gold can also reach 100 wt% when applied to a waste catalyst by adding a Soxhlet extraction. The results show that this method is not only efficient, mild, and environmentally friendly, but also has strong adaptability and wide application prospects.Keywords:gold recovery;ionic liquid;free radical;waste catalyst;oxidation-complexation
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BIOMEDICAL CHROMATOGRAPHY
·
2021
·Vol. 36
·期 1
·e5239
·
IF 1.902
Xiao-fang Ma,Qi Zhao,Yan Cheng,Dong-Mei Yan,Wei-Feng Zhu,Fei Li
Coumarins are a group of natural compounds commonly found in the families of Rutaceae and Umbelliferae. 7-Isopentenyloxycoumarin (ISC), auraptene (AUR), and umbelliprenin (UM) belong to prenyloxycoumarins (PYCs), which link isopentenyl, geranyl, and farnesyl group at C7 position, respectively. The substituent of 7-ethoxycoumarin (ETC) is the ethyl group. In this study, UPLC–ESI–QTOF–MS (ultra-performance liquid chromatography–electrospray ionization–quadrupole time of flight–MS)-based metabolomics was used to evaluate the in vivo and in vitro metabolism of PYCs. Results showed that ETC produced 10 known metabolites, and ISC was transformed into 17 metabolites in vivo and in vitro , which were undescribed compounds. A total of 35 AUR metabolites, including 34 undescribed metabolites were identified, and 21 metabolites were reported for the first time in UM. The results indicated that hydroxylation and N -acetylcysteine conjugation were the common metabolic reactions for PYCs. The metabolic rates of ETC, ISC, AUR and UM were 26%, 36%, 81%, and 38%, respectively, in human liver microsome, while they were 24%, 40%, 80%, and 37%, respectively, in mouse liver microsomes. In addition, recombinant cytochrome P450s (CYPs) screening showed that CYP1A1, 2C19, 3A4, and 3A5 were the major metabolic enzymes involved in the formation of hydroxylation metabolites. Together, these results suggest that the isopentenyl group plays an important role in the metabolism of PYCs.
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ACS Applied Materials & Interfaces
·
2019
·
IF 8.456
Jinyao Zhong,Zheng Xiao,Wenyue Liang,Yifei Wu,Qiaojue Ye,Haitao Xu,Haidong Deng,Liang Shen,Xiliang Feng,Yongbing Long
Microcavity is an efficient approach to manufacture colorful semitransparent organic solar cells (ST-OSCs) with high color purity by tailoring the transmission spectrum to narrow peaks. However, in this type of colorful semitransparent devices, high power conversion efficiency (PCE) and high peak transmittance are not yet simultaneously achieved. This paper proposes a new type of microcavity structure to achieve colorful ST-OSCs with both high PCE and high peak transmittance, in which a hybrid Au/Ag electrode is used as a mirror and WO3 is used as a spacer layer. First, it is demonstrated that the hybrid Au/Ag electrode mirror brings about an improvement of 7.7 and 5.5% for PCE and peak transmittance, respectively, when compared with those of the reference devices using the Ag electrode mirror. Specifically, the PCE of the optimized devices reaches the satisfactory value of over 9%, and the peak transmittance is over 25%. This value of PCE is the highest one reported so far for the microcavity-based ST-OSCs with the same peak transmittance. Second, it is demonstrated that the second-order resonance of the microcavity can be used to improve the color purity of green ST-OSCs by narrowing the transmission peak, and the combination of the second-order and third-order resonance can be used to construct colorful ST-OSCs with mixed colors. Thus, a novel approach is developed to tune the color of ST-OSCs, which is based on high-order resonance modes of the microcavity.
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JOURNAL OF RAMAN SPECTROSCOPY
·
2018
·Vol. 50
·期 1
·26-33
·
IF 2.879
Si Chen,Zhinan Guo,David K. Sang,Huide Wang,Yanhua Xu,Siying Tang,Qian Luo,Rui Cao,Xiaolei Wang,Ling Zhang,Jianghai Liao,Han Zhang,Xue-Feng Yu,Bing Zhao,Dianyuan Fan
This paper reports the fabrication of gold-patterned microarray chips for fast and ultrasensitive surface enhanced Raman scattering (SERS) detection of trace samples. By micro-nano machining based on electron-beam lithography, magnetron sputtering, and chemical modification, gold-patterned microarray chips with hydrophilic and hydrophobic periodic structures are fabricated, and a polyethylene glycol (PEG) layer is coated on the surface of the gold well, making the chips long-term stable. The hydrophilic surface of each gold well is surrounded by a hydrophobic layer, which makes the ultratrace sample amount for SERS measurement only 0.3 μl. In the detection of malachite green (MG), 4-mercaptopyridine (4-MPY), rhodamine 6G (R6G), and melamine, great enhanced SERS signals with the detection limit reaching nM level can be achieved due to the enrichment effect of the periodic structures and the hot-spots generated between the sandwich structure built on the gold wells. Such gold-patterned microarray chip is promising in fast and ultrasensitive SERS detection of various chemical and biological species with trace amount.
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Chemical Science
·
2013
·Vol. 5
·期 3
·1082-1090
·
IF 8.314
Gang Lu,Peng Zhang,Dongqing Sun,Lei Wang,Kebin Zhou,Zhi-Xiang Wang,Guo-Cong Guo
Clean gold surface is inactive toward H2, however, computations, aided by experiments, reveal that gold surface could serve as a Lewis acid coupling with Lewis bases (e.g. imine and nitrile) to construct effective frustrated Lewis pairs (FLPs) to activate H2 and subsequently to achieve hydrogenation of small imines and nitriles. The Lewis base-coupled Au FLPs avoid tight adsorption of Lewis bases to gold surface via repulsion between nitrogen lone pair and the filled d-band electrons of the gold surface. This is different from the normal FLPs that use sterically demanding groups or a molecular scaffold to prevent formation of stable Lewis acid–base complexes. The enhanced reactivity of the gold surface toward H2 is due to the synergetic catalytic effects of Lewis acid (Au surface) and the coupled Lewis base (imine or nitrile), which is supported by projected density of states (PDOS) analyses. Among Cu, Ag and Au surfaces, Au surface exhibits such reactivity most significantly, because Au is much more electronegative than Cu and Ag. The study enriches the FLP chemistry by adding a new type (heterogeneous) of FLPs and reveals a new reaction mode for gold surface.
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ACS Applied Materials & Interfaces
·
2013
·
IF 5.008
Shi Peng,Qiang Zheng,Xin Zhang,Linghui Dai,Jingxian Zhu,Yanbin Pi,Xiaoqing Hu,Wenqing Cheng,Chunyan Zhou,Yinlin Sha,Yingfang Ao
A disintegrin and metalloproteinase with thrombospondin motif-4 (ADAMTS-4) plays a pivotal role in degrading aggrecan, which is an early event in cartilage degrading joint diseases such as osteoarthritis (OA). Detection of ADAMTS-4 activity could provide useful clinical information for early diagnosis of such diseases and disease-modifying therapy. Therefore, we developed a ADAMTS-4 detective fluorescent turn-on AuNP probe (ADAMTS-4-D-Au probe) by conjugating gold nanoparticles with a FITC-modified ADAMTS-4-specific peptide (DVQEFRGVTAVIR). When the ADAMTS-4-D-Au probe was incubated with ADAMTS-4, the fluorescence recovered and fluorescence intensity markedly increased in proportion to concentrations of ADAMTS-4 and the probe. A nearly 3-fold increase in fluorescent intensity in response to only 3.9 pM of ADAMTS-4 was detected, whereas almost no fluorescence recovery was observed when the probe was incubated with matrix metalloproteinase (MMP)-1, -3, and -13. These results indicate a relative high sensitivity and specificity of the probe. Moreover, ADAMTS-4-D-Au probe was used to detect ADAMTS-4 activity in synovial fluid from 11 knee surgery patients. A substantial increase in fluorescent intensity was observed in the acute joint injury group as compared to the chronic joint injury and end-stage OA groups, indicating that this simple and low-cost sensing system might serve as a new detection method for ADAMTS-4 activity in biological samples and in screens for inhibitors for ADAMTS-4-related joint diseases. Additionally, this probe could be a potential biomarker for early diagnosis of cartilage-degrading joint diseases.
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高影响因子
FOOD CONTROL
·
2024
·
IF 5.6
Jian-cheng Hu,Peng Wen,Yu Wang,Jin-yi Yang,Zhi-li Xiao,Zhen-lin Xu,Yu-dong Shen,Hong Wang,Bruce D. Hammock
The accumulation of quinalphos pesticide in agricultural products have detrimental effects to human body and environment, hence, an efficient and sensitive detection approach is desirable. In this study, a label-free electrochemical immunosensor based on the directly immobilizing nanobody onto functionalized polyvinyl alcohol/gelatin-gold nanoparticles nanofiber membrane (PVA/G-AuNPs NFM) was fabricated. First, a homogeneous PVA/G-AuNPs NFM with multiple-porosity structure and appropriate hydrophilicity was prepared. Then, the electrochemical immunosensor was assembled and under the optimized conditions, the prepared biosensor exhibited good detection performance towards quinalphos with the linear range and limit of detection being 0.06–1000 ng/mL and 50.74 pg/mL (S/N = 3), respectively. Moreover, the sensor presented good specificity, regenerability and stability, maintaining more than 90% activity after 5 times of regeneration and about 90% activity after 6 weeks of storage. Finally, the average recoveries of quinalphos from food samples were 89.68%–110.88% with the coefficient of variation being 1.65%–7.81%, showing good correlation with UPLC-MS/MS (R 2 = 0.9859), indicating the accuracy of the proposed electrochemical immunosensor assay. Overall, the label-free electrochemical immunosensor presents a novel approach for the rapid and sensitive detection of quinalphos and other pesticide residues.
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Chinese Physics B
·
2024
·Vol. 33
·期 9
·098501
·
IF 1.5
Heng Yang,Mingjun Ma,Yongfeng Pei,Yufan Kang,Jialu Yan,Dong He,Changzhong Jiang,Wenqing Li,Xiangheng Xiao
Ultraviolet photodetectors (UV PDs) are widely used in civilian, scientific, and military fields due to their high sensitivity and low false alarm rates. We present a temperature-dependent Lewis acid p-type doping method for transition metal dichalcogenides (TMDs), which can effectively be used to extend the optical response range. The p-type doping based on surface charge transfer involves the chemical adsorption of the Lewis acid SnCl4 as a light absorption layer on the surface of WS2, significantly enhancing its UV photodetection performance. Under 365 nm laser irradiation, WS2 PDs exhibit response speed of 24 ms/20 ms, responsivity of 660 mA/W, detectivity of 3.3 × 1011 Jones, and external quantum efficiency of 226%. Moreover, we successfully apply this doping method to other TMDs materials (such as MoS2, MoSe2, and WSe2) and fabricate WS2 lateral p–n heterojunction PDs.
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FOOD CHEMISTRY
·
2024
·
IF 8.5
Xia Niu,Wen-Yuan Pei,Jian-Fang Ma
Herein, a novel FeCoNi(b)-800 ternary metal nanoalloy was uniformly mixed with reduced graphene oxide (RGO) to synthesize the FeCoNi(b)-800@RGO(2:1) composite. The addition of RGO not only stopped the accumulation of FeCoNi(b)-800 alloy, but also heightened the electrocatalytic activity of composite. Particularly, the FeCoNi(b)-800@RGO(2:1) composite displayed the significantly strong electrocatalytic capacity for the reduction of roxarsone (ROX). Furthermore, the FeCoNi(b)-800@RGO(2:1) composite possessed enough porosity and metal catalytic sites, facilitating the transport and electrochemical reduction of the ROX. Thus, the FeCoNi(b)-800@RGO(2:1) composite modified glassy carbon electrode (FeCoNi(b)-800@RGO(2:1)/GCE) showed the superb electrochemical detection effect for ROX with relatively wide working range (0.1–1500 μM) and low detection limit (0.013 μM). Importantly, the FeCoNi(b)-800@RGO(2:1)/GCE sensor could accurately determine the contents of ROX in actual pork, chicken, duck and egg samples, indicating that it had good suitability in food safety monitoring.
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高影响因子
ANALYTICA CHIMICA ACTA
·
2025
·
IF 6
Yijing Kuang,Wei Yuan,Xuyuan Chen,Xiaoning Wang,Xiaoying Wang
Background The expression of oncoprotein c-Myc (OP c-Myc ) in blood is closely related to the occurrence and development of various tumors. Common detection methods have the disadvantages of complicated procedures, expensive instruments, or low sensitivity. Currently, several single-mode immunosensors have been developed to detect OP c-Myc and overcome the above shortcomings. However, they are susceptible to the interference of the sensing interface and the external environment, which may lead to false-positive or false-negative results. Therefore, sensitive and accurate assessment of OP c-Myc levels in the blood is very important for the early diagnosis and monitoring of tumors. Results A novel electrochemiluminescence (ECL)-electrochemical (EC) dual-mode immunosensor was developed for the sensitive detection of trace OP c-Myc . Gold nanoparticles-magnetic reduced graphene oxide (AuMrGO), with a large surface area and conductivity, were stably fixed on a magnetic glassy carbon electrode and utilized as the immobilization platform. Ruthenium(II)tris(bipyridine) (Ru) doped Au, Ag, and Pd trimetallic nanocomposite (Tri-Ru) with excellent ECL and EC properties was synthesized by mechanical alloying method and used as the bifunctional signaling label. Further, combined with the trace detection advantages of indirect competition, the convenient and sensitive dual-mode detection of OP c-Myc was realized. The results showed a strong linear relationship for concentrations from 10 pg L −1 to 0.1 μg L −1 in ECL mode and from 0.1 ng L −1 to 1 μg L −1 in EC mode, with limits of detection (LOD) of 4.9 pg L −1 and 30 pg L −1 , respectively. The assay performed good analytical performances and clinical practicability in lymphoma patients’ blood samples. Significance This is the first detection of OP c-Myc using an ECL immunosensor, and it is also the first attempt to use a dual-mode detection strategy for OP c-Myc . The strategy could be used for sensing and detecting other proteomic tumor markers and established a promising platform for early auxiliary diagnosis and monitoring of cancers.
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高影响因子
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